Citations for
1AGT, ERAP1, ERP44
ERp44 Exerts Redox-Dependent Control of Blood Pressure at the ER.
Hisatsune C, Ebisui E, Usui M, Ogawa N, Suzuki A, Mataga N, Takahashi-Iwanaga H, Mikoshiba K.
Mol Cell 58(6):1015-27. doi: 10.1016/j.molcel.2015.04.008. Epub 2015 May 7. 2015
2AGT, CEBPA
Dynamic CCAAT/enhancer binding protein-associated changes of DNA methylation in the angiotensinogen gene.
Wang F, Demura M, Cheng Y, Zhu A, Karashima S, Yoneda T, Demura Y, Maeda Y, Namiki M, Ono K, Nakamura Y, Sasano H, Akagi T, Yamagishi M, Saijoh K, Takeda Y.
Hypertension 63(2):281-8. doi: 10.1161/HYPERTENSIONAHA.113.02303. Epub 2013 Nov 4. 2014
3AGT, MSR1
Class A scavenger receptor deficiency augments angiotensin II-induced vascular remodeling.
Qian L, Li X, Fang R, Wang Z, Xu Y, Zhang H, Bai H, Yang Q, Zhu X, Ben J, Xu Y, Chen Q.
Biochem Pharmacol 90(3):254-64. doi: 10.1016/j.bcp.2014.05.015. Epub 2014 May 27. 2014
4AGT, CAV1
Caveolin 1 is critical for abdominal aortic aneurysm formation induced by angiotensin II and inhibition of lysyl oxidase.
Takayanagi T, Crawford KJ, Kobayashi T, Obama T, Tsuji T, Elliott KJ, Hashimoto T, Rizzo V, Eguchi S.
Clin Sci (Lond) 126(11):785-94. doi: 10.1042/CS20130660. 2014
5AGT, RGN
Senescence marker protein 30 inhibits angiotensin II-induced cardiac hypertrophy and diastolic dysfunction.
Misaka T, Suzuki S, Miyata M, Kobayashi A, Ishigami A, Shishido T, Saitoh S, Kubota I, Takeishi Y.
Biochem Biophys Res Commun 439(1):142-7. doi: 10.1016/j.bbrc.2013.08.002. Epub 2013 Aug 9. 2013
6ACE, AGT
The influence of Angiotensin converting enzyme and angiotensinogen gene polymorphisms on hypertrophic cardiomyopathy.
Luo R, Li X, Wang Y, Li Y, Deng Y, Wan Y, Jiang Z, Hua W, Wu X.
PLoS One 8(10):e77030. doi: 10.1371/journal.pone.0077030. eCollection 2013. Review. 2013
7AGT
Association of angiotensinogen gene polymorphisms and angiogenic factors with preeclampsia in Chinese women.
Song C, Xie S, Wang J, Lian J, Diao B, Tang Y.
Gynecol Obstet Invest 76(1):64-8. doi: 10.1159/000352070. Epub 2013 Jul 13. 2013
8AGT
Melatonin ameliorates angiotensin II-induced vascular endothelial damage via its antioxidative properties.
Nakao T, Morita H, Maemura K, Amiya E, Inajima T, Saito Y, Watanabe M, Manabe I, Kurabayashi M, Nagai R, Komuro I.
J Pineal Res 55(3):287-93. doi: 10.1111/jpi.12071. Epub 2013 Jul 1. 2013
9AGT
Angiotensin II contributes to diabetic renal dysfunction in rodents and humans via Notch1/Snail pathway.
Gagliardini E, Perico N, Rizzo P, Buelli S, Longaretti L, Perico L, Tomasoni S, Zoja C, Macconi D, Morigi M, Remuzzi G, Benigni A.
Am J Pathol 183(1):119-30. doi: 10.1016/j.ajpath.2013.03.025. Epub 2013 May 23. 2013
10AGT, MMP9
Important role of the angiotensin II pathway in producing matrix metalloproteinase-9 in human thoracic aortic aneurysms.
Nagasawa A, Yoshimura K, Suzuki R, Mikamo A, Yamashita O, Ikeda Y, Tsuchida M, Hamano K.
J Surg Res 183(1):472-7. doi: 10.1016/j.jss.2012.12.012. Epub 2013 Jan 1. 2013
11AGT
Association of angiotensinogen M235T gene polymorphism with end-stage renal disease risk: a meta-analysis.
Zhou TB, Yin SS, Qin YH.
Mol Biol Rep 40(2):765-72. doi: 10.1007/s11033-012-2114-x. Epub 2012 Oct 13. 2013
12ACE, AGT, AGTR1, REN, RTD1, RTD2, RTD3, RTD4
Spectrum of mutations in the renin-angiotensin system genes in autosomal recessive renal tubular dysgenesis.
Gribouval O, Morinière V, Pawtowski A, Arrondel C, Sallinen SL, Saloranta C, Clericuzio C, Viot G, Tantau J, Blesson S, Cloarec S, Machet MC, Chitayat D, Thauvin C, Laurent N, Sampson JR, Bernstein JA, Clemenson A, Prieur F, Daniel L, Levy-Mozziconacci A, Lachlan K, Alessandri JL, Cartault F, Rivière JP, Picard N, Baumann C, Delezoide AL, Belar Ortega M, Chassaing N, Labrune P, Yu S, Firth H, Wellesley D, Bitzan M, Alfares A, Braverman N, Krogh L, Tolmie J, Gaspar H, Doray B, Majore S, Bonneau D, Triau S, Loirat C, David A, Bartholdi D, Peleg A, Brackman D, Stone R, DeBerardinis R, Corvol P, Michaud A, Antignac C, Gubler MC.
Hum Mutat 33(2):316-26. doi: 10.1002/humu.21661. Epub 2011 Dec 22. Review. 2012
13AGT, BGLAP
From skeleton to cytoskeleton: osteocalcin transforms vascular fibroblasts to myofibroblasts via angiotensin II and Toll-like receptor 4.
Yuen CY, Wong SL, Lau CW, Tsang SY, Xu A, Zhu Z, Ng CF, Yao X, Kong SK, Lee HK, Huang Y.
Circ Res 111(3):e55-66. doi: 10.1161/CIRCRESAHA.112.271361. Epub 2012 Jun 7. 2012
14AGT, STAR
Angiotensin II-dependent transcriptional activation of human steroidogenic acute regulatory protein gene by a 25-kDa cAMP-responsive element modulator protein isoform and Yin Yang 1.
Meier RK, Clark BJ.
Endocrinology 153(3):1256-68. doi: 10.1210/en.2011-1744. Epub 2012 Jan 17. 2012
15AGT
Angiotensin II increases the permeability and PV-1 expression of endothelial cells.
Bodor C, Nagy JP, Végh B, Németh A, Jenei A, MirzaHosseini S, Sebe A, Rosivall L.
Am J Physiol Cell Physiol 302(1):C267-76. doi: 10.1152/ajpcell.00138.2011. Epub 2011 Oct 19. 2012
16AGT, GATA6
Angiotensin II induces apoptosis in intestinal epithelial cells through the AT2 receptor, GATA-6 and the Bax pathway.
Sun L, Wang W, Xiao W, Liang H, Yang Y, Yang H.
Biochem Biophys Res Commun 424(4):663-8. doi: 10.1016/j.bbrc.2012.07.003. Epub 2012 Jul 7. 2012
17AGT, FLT1, SYK
Angiotensin II-induced process of angiogenesis is mediated by spleen tyrosine kinase via VEGF receptor-1 phosphorylation.
Buharalioglu CK, Song CY, Yaghini FA, Ghafoor HU, Motiwala M, Adris T, Estes AM, Malik KU.
Am J Physiol Heart Circ Physiol 301(3):H1043-55. doi: 10.1152/ajpheart.01018.2010. Epub 2011 Jun 3. 2011
18AGT, ARHGEF1
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.
Guilluy C, Brégeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G.
Nat Med 16(2):183-90. Epub 2010 Jan 24.PMID: 20098430 2010
19AGT, AGTR1
Angiotensin II/angiotensin II type I receptor (AT1R) signaling promotes MCF-7 breast cancer cells survival via PI3-kinase/Akt pathway.
Zhao Y, Chen X, Cai L, Yang Y, Sui G, Fu S.
J Cell Physiol 225(1):168-73.PMID: 20458733 2010
20AGT, HNF4A
A nuclear receptor, hepatocyte nuclear factor 4, differently contributes to the human and mouse angiotensinogen promoter activities.
Oishi T, Date S, Shimamoto Y, Saito T, Hirota K, Sugaya T, Kon Y, Fukamizu A, Tanimoto K.
J Recept Signal Transduct Res 30(6):484-92. Epub 2010 Aug 4. 2010
21AGT, ELF3
The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling.
Zhan Y, Yuan L, Kondo M, Oettgen P.
Am J Hypertens 23(12):1312-7. doi: 10.1038/ajh.2010.164. Epub 2010 Aug 5. 2010
22AGT, AGTR1
Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging.
Modrick ML, Didion SP, Sigmund CD, Faraci FM.
Am J Physiol Heart Circ Physiol 296(6):H1914-9. Epub 2009 Apr 24.PMID: 19395552 2009
23AGT, AGTR1, AGTR2
Neuronal and glial cell expression of angiotensin II type 1 (AT1) and type 2 (AT2) receptors in the rat retina.
Downie LE, Vessey K, Miller A, Ward MM, Pianta MJ, Vingrys AJ, Wilkinson-Berka JL, Fletcher EL.
Neuroscience 161(1):195-213. Epub 2009 Mar 17.PMID: 19298848 2009
24AGT, TTF1
Expression and role of TTF-1 in the rat suprachiasmatic nucleus.
Son YJ, Yun CH, Kim JG, Park JW, Kim JH, Kang SG, Lee BJ.
Biochem Biophys Res Commun 380(3):559-63. doi: 10.1016/j.bbrc.2009.01.119. Epub 2009 Jan 25. 2009
25AGT, MGP
Upregulation of cardiac matrix Gla protein expression in response to hypertrophic stimuli.
Mustonen E, Pohjolainen V, Aro J, Pikkarainen S, Leskinen H, Ruskoaho H, Rysä J.
Blood Press 18(5):286-93. doi: 10.3109/08037050903244643. 2009
26AGT, INS, MAPK7, MODY10
Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells.
Sharma G, Goalstone ML.
Biochem Biophys Res Commun 354(4):1078-83. Epub 2007 Jan 26. 2007
27RTD1, AGT, AGTR1, ACE, RTD2, REN, RTD4, RTD3
Inherited renal tubular dysgenesis: the first patients surviving the neonatal period.
Zingg-Schenk A, Bacchetta J, Corvol P, Michaud A, Stallmach T, Cochat P, Gribouval O, Gubler MC, Neuhaus TJ.
Eur J Pediatr [Epub ahead of print] 2007
28AGTR1, CYP11B2, AGT, CMA1, ACE
RAAS gene polymorphisms influence progression of pediatric hypertrophic cardiomyopathy.
Kaufman BD, Auerbach S, Reddy S, Manlhiot C, Deng L, Prakash A, Printz BF, Gruber D, Papavassiliou DP, Hsu DT, Sehnert AJ, Chung WK, Mital S.
Hum Genet 122(5):515-23. Epub 2007 Sep 13. 2007
29AGT, CTSF
Angiotensin II increases expression and secretion of cathepsin F in cultured human monocyte-derived macrophages: an angiotensin II type 2 receptor-mediated effect.
Kaakinen R, Lindstedt KA, Sneck M, Kovanen PT, Oörni K.
Atherosclerosis 192(2):323-7. Epub 2006 Sep 11. 2007
30AGT
Sequence variants of ACE, AGT, AT1R, and PAI-1 as genetic risk factors for vascular dementia.
Kim Y, Kim JH, Nam YJ, Kim YJ, Yu KH, Lee BC, Lee C.
Neurosci Lett 401(3):276-9. Epub 2006 Apr 17. 2006
31RTD1, AGT
A case surviving for over a year of renal tubular dysgenesis with compound heterozygous angiotensinogen gene mutations.
Uematsu M, Sakamoto O, Nishio T, Ohura T, Matsuda T, Inagaki T, Abe T, Okamura K, Kondo Y, Tsuchiya S.
Am J Med Genet A 140(21):2355-60. 2006
32AGT
Upregulation of human angiotensinogen (AGT) gene transcription by interferon-gamma: involvement of the STAT1-binding motif in the AGT promoter.
Jain S, Shah M, Li Y, Vinukonda G, Sehgal PB, Kumar A.
Biochim Biophys Acta 1759(7):340-7. Epub 2006 Jul 28. 2006
33AGT, ADAM17, EGFR
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach.
Lautrette A, Li S, Alili R, Sunnarborg SW, Burtin M, Lee DC, Friedlander G, Terzi F.
Nat Med 11(8):867-74. Epub 2005 Jul 24. 2005
34RTD1, AGT, AGTR1, ACE, RTD2, REN, RTD4, RTD3
Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis.
Gribouval O, Gonzales M, Neuhaus T, Aziza J, Bieth E, Laurent N, Bouton JM, Feuillet F, Makni S, Ben Amar H, Laube G, Delezoide AL, Bouvier R, Dijoud F, Ollagnon-Roman E, Roume J, Joubert M, Antignac C, Gubler MC.
Nat Genet 37(9):964-8. Epub 2005 Aug 14. 2005
35AGTRAP, CAMLG, NFATC2, AGT
Identification of calcium-modulating cyclophilin ligand (CAML) as transducer of angiotensin II-mediated nuclear factor of activated T cells (NFAT) activation.
Guo S, Lopez-Ilasaca M, Dzau VJ.
J Biol Chem 280(13):12536-41. Epub 2005 Jan 24. 2005
36RREB1, AGT
Finb, a multiple zinc finger protein, represses transcription of the human angiotensinogen gene.
Date S, Nibu Y, Yanai K, Hirata J, Yagami K, Fukamizu A.
Int J Mol Med 13(5):637-42. 2004
37SPP1, AGT
AP-1 is involved in UTP-induced osteopontin expression in arterial smooth muscle cells.
Renault MA, Jalvy S, Belloc I, Pasquet S, Sena S, Olive M, Desgranges C, Gadeau AP.
Circ Res 93(7):674-81. Epub 2003 Sep 11. 2003
38AGT, YBX1
Molecular cloning and functional analysis of a factor that binds to the proximal promoter of human angiotensinogen.
Nakajima T, Inoue I, Cheng T, Lalouel JM.
J Hum Genet 47(1):7-13. 2002
39ACE, AGT
Angiotensin I-converting enzyme gene insertion/deletion and angiotensinogen M235T polymorphisms: risk of chronic renal failure. End-Stage Renal Disease Study Group.
Gumprecht J, Zychma MJ, Grzeszczak W, Zukowska-Szczechowska E.
Kidney Int 58(2):513-9. 2000
40AGT
Role of C/A polymorphism at -20 on the expression of human angiotensinogen gene.
Zhao YY, et al.
Hypertension 33(1):108-15. 1999
41AGT
Angiotensinogen M235T polymorphism is associated with plasma angiotensinogen and cardiovascular disease.
Winkelmann BR, et al.
Am Heart J 137(4 Pt 1):698-705. 1999
42AGT, AGTR1, ACE
A multilocus genotyping assay for candidate markers of cardiovascular disease risk.
Cheng S, Grow MA, Pallaud C, Klitz W, Erlich HA, Visvikis S, Chen JJ, Pullinger CR, Malloy MJ, Siest G, Kane JP.
Genome Res 9(10):936-49 1999
43AGT
Angiotensinogen T174M and M235T gene polymorphisms are associated with the extent of coronary atherosclerosis.
Gardemann A, Stricker J, Humme J, Nguyen QD, Katz N, Philipp M, Tillmanns H, Hehrlein FW, Haberbosch W.
Atherosclerosis 145(2):309-14 1999
44AGT
Exclusion of angiotensinogen gene in molecular basis of human hypertension: sibpair linkage and association analyses in Australian anglo-caucasians.
Wang WY, Glenn CL, Zhang W, Benjafield AV, Nyholt DR, Morris BJ.
Am J Med Genet 87(1):53-60 1999
45AGT, ACE
Polymorphism in the angiotensin converting enzyme but not in the angiotensinogen gene is associated with hypertension and type 2 diabetes: the Skaraborg Hypertension and diabetes project.
Bengtsson K, Orho-Melander M, Lindblad U, Melander O, Bog-Hansen E, Ranstam J, Rastam L, Groop L.
J Hypertens 17(11):1569-75 1999
46AGT
Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression.
Cui Y, et al.
Gene 224(1-2):97-107. 1998
47AGT, AGTR1, ACE
Genetic polymorphisms of the renin-angiotensin system and angiographic extent and severity of coronary artery disease : the CORGENE study.
Jeunemaitre X, et al.
Hum Genet 99 : 66-73. 1997
48AGT
Haplotypes of angiotensinogen in essential hypertension.
Jeunemaitre X, Inoue I, Williams C, Charru A, Tichet J, Powers M, Sharma AM, Gimenez-Roqueplo AP, Hata A, Corvol P, Lalouel JM.
Am J Hum Genet 60(6):1448-60. 1997
49AGT, ACE
Association of angiotensinogen gene T235 variant with progression of immunoglobin A nephropathy in Caucasian patients.
Pei Y, Scholey J, Thai K, Suzuki M, Cattran D.
J Clin Invest 100(4):814-20. 1997
50AGT
DNA polymorphisms and linkage disequilibrium in the angiotensinogen gene.
Morgan L, et al.
Hum Genet 98 : 194-198. 1996
51AGT
Short report on DNA marker at candidate locus. Nested PCR for detection of the Met235-Thr variant of the human angiotensinogen gene from small volumes of serum.
Davis DR, et al.
Clin Genet 50 : 435-436. 1996
52AGT
Genetic control of blood pressure and the angiotensinogen locus.
Kim HS, et al.
Proc Natl Acad Sci U S A 92 : 2735-2739. 1995
53AGT
Detection and characterization of new mutations in the human angiotensinogen gene (AGT).
Hixson JE, et al.
Hum Genet 96 : 110-112. 1995
54AGT
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease.
Katsuya T, et al.
Lancet 345 : 1600-1603. 1995
55AGT
Variation at the M235T locus of the angiotensinogen gene and essential hypertension : a population-based case-control study from Rochester, Minnesota.
Fornage M, et al.
Hum Genet 96 : 295-300. 1995
56AGT
Linkage of the angiotensinogen gene locus to human essential hypertension in African Caribbeans.
Caulfield M, et al.
J Clin Invest 96 : 687-692. 1995
57AGT
A mutation of angiotensinogen in a patient with preeclampsia leads to altered kinetics of the renin-angiotensin system.
Inoue I, et al.
J Biol Chem 270 : 11430-11436. 1995
58AGT
Linkage of the angiotensinogen gene to essential hypertension.
Caulfield M, et al.
N Engl J Med 330 : 1629-1633. 1994
59AGT
Rapid detection of the hypertension-associated Met235-Thr allele of the human angiotensinogen gene.
Russ AP, et al.
Hum Mol Genet 2 : 609-610. 1993
60AGT
Cross-sectional analysis of Met235-Thr variant of angiotensinogen gene in severe, familial hypertension.
Bennett CL, et al.
Biochem Biophys Res Commun 197 : 833-839. 1993
61AGT
A molecular variant of angiotensinogen associated with preeclampsia.
Ward K, et al.
Nat Genet 4 : 59-61. 1993
62AGT
Molecular basis of human hypertension : role of angiotensinogen.
Jeunemaitre X, et al.
Cell 71 : 169-180. 1992
63AGT
Dinucleotide repeat polymorphism in the human angiotensinogen gene.
Kotelevtsev YV, et al.
Nucleic Acids Res 19 : 6978. 1991
64AGT
Assignment of the human angiotensinogen gene to chromosome 1q42-43 by nonisotopic in situ hybridization.
Isa MN, et al.
Genomics 8 : 598-600. 1990
65AGT
Assignment by in situ hybridization of the angiotensinogen gene to chromosome band 1q4, the same region as the human renin gene.
Gaillard-Sanchez I, et al.
Hum Genet 84 : 341-343. 1990