Citations for
Dimerization of pro-oncogenic protein Anterior Gradient 2 is required for the interaction with BiP/GRP78.
Ryu J, Park SG, Lee PY, Cho S, Lee do H, Kim GH, Kim JH, Park BC.
Biochem Biophys Res Commun 430(2):610-5. doi: 10.1016/j.bbrc.2012.11.105. Epub 2012 Dec 4. 2013
AGR2 gene function requires a unique endoplasmic reticulum localization motif.
Gupta A, Dong A, Lowe AW.
J Biol Chem 287(7):4773-82. doi: 10.1074/jbc.M111.301531. Epub 2011 Dec 19. 2012
AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D.
Dumartin L, Whiteman HJ, Weeks ME, Hariharan D, Dmitrovic B, Iacobuzio-Donahue CA, Brentnall TA, Bronner MP, Feakins RM, Timms JF, Brennan C, Lemoine NR, Crnogorac-Jurcevic T.
Cancer Res 71(22):7091-102. Epub 2011 Sep 26. 2011
AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration.
Park K, Chung YJ, So H, Kim K, Park J, Oh M, Jo M, Choi K, Lee EJ, Choi YL, Song SY, Bae DS, Kim BG, Lee JH.
Exp Mol Med 43(2):91-100. 2011
The anterior gradient 2 (AGR2) gene is overexpressed in prostate cancer and may be useful as a urine sediment marker for prostate cancer detection.
Bu H, Bormann S, Schäfer G, Horninger W, Massoner P, Neeb A, Lakshmanan VK, Maddalo D, Nestl A, Sültmann H, Cato AC, Klocker H.
Prostate 71(6):575-87. doi: 10.1002/pros.21273. Epub 2010 Oct 13. 2011
The human adenocarcinoma-associated gene, AGR2, induces expression of amphiregulin through Hippo pathway co-activator YAP1 activation.
Dong A, Gupta A, Pai RK, Tun M, Lowe AW.
J Biol Chem 286(20):18301-10. Epub 2011 Mar 26. 2011
Role of pro-oncogenic protein disulfide isomerase (PDI) family member anterior gradient 2 (AGR2) in the control of endoplasmic reticulum homeostasis.
Higa A, Mulot A, Delom F, Bouchecareilh M, Nguyên DT, Boismenu D, Wise MJ, Chevet E.
J Biol Chem 286(52):44855-68. doi: 10.1074/jbc.M111.275529. Epub 2011 Oct 24. 2011
Differential expression of anterior gradient gene AGR2 in prostate cancer.
Maresh EL, Mah V, Alavi M, Horvath S, Bagryanova L, Liebeskind ES, Knutzen LA, Zhou Y, Chia D, Liu AY, Goodglick L.
BMC Cancer 10:680. 2010
Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin.
Vanderlaag KE, Hudak S, Bald L, Fayadat-Dilman L, Sathe M, Grein J, Janatpour MJ.
Breast Cancer Res 12(3):R32. Epub 2010 Jun 4. 2010
The metastasis-associated anterior gradient 2 protein is correlated with poor survival of breast cancer patients.
Barraclough DL, Platt-Higgins A, de Silva Rudland S, Barraclough R, Winstanley J, West CR, Rudland PS.
Am J Pathol 175(5):1848-57. Epub 2009 Oct 15. 2009
The protein disulfide isomerase AGR2 is essential for production of intestinal mucus.
Park SW, Zhen G, Verhaeghe C, Nakagami Y, Nguyenvu LT, Barczak AJ, Killeen N, Erle DJ.
Proc Natl Acad Sci U S A 106(17):6950-5. Epub 2009 Apr 9. 2009
Anterior gradient 2 is expressed and secreted during the development of pancreatic cancer and promotes cancer cell survival.
Ramachandran V, Arumugam T, Wang H, Logsdon CD.
Cancer Res 68(19):7811-8. 2008
Physiological stress induces the metastasis marker AGR2 in breast cancer cells.
Zweitzig DR, Smirnov DA, Connelly MC, Terstappen LW, O'Hara SM, Moran E.
Mol Cell Biochem 306(1-2):255-60. Epub 2007 Aug 11. 2007
Evaluation of AGR2 and AGR3 as candidate genes for inflammatory bowel disease.
Zheng W, Rosenstiel P, Huse K, Sina C, Valentonyte R, Mah N, Zeitlmann L, Grosse J, Ruf N, Nürnberg P, Costello CM, Onnie C, Mathew C, Platzer M, Schreiber S, Hampe J.
Genes Immun 7(1):11-8. 2006
AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer.
Zhang JS, Gong A, Cheville JC, Smith DI, Young CY.
Genes Chromosomes Cancer 43(3):249-59. 2005
Localization of the human anterior gradient-2 gene (AGR2) to chromosome band 7p21.3 by radiation hybrid mapping and fluorescencein situ hybridisation.
Petek E, Windpassinger C, Egger H, Kroisel PM, Wagner K.
Cytogenet Cell Genet 89(3-4):141-2. No abstract available. 2000
Anterior specification of embryonic ectoderm: the role of the Xenopus cement gland-specific gene XAG-2.
Aberger F, Weidinger G, Grunz H, Richter K.
Mech Dev 72(1-2):115-30. 1998
hAG-2, the human homologue of the Xenopus laevis cement gland gene XAG-2, is coexpressed with estrogen receptor in breast cancer cell lines.
Thompson DA, Weigel RJ.
Biochem Biophys Res Commun 251(1):111-6. 1998