1 | AFP, ZBTB20
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| ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein gene.
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| Zhang H, Cao D, Zhou L, Zhang Y, Guo X, Li H, Chen Y, Spear BT, Wu JW, Xie Z, Zhang WJ.
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| Sci Rep 5:11979. doi: 10.1038/srep11979.
2015
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2 | AFP, ALB
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| Molecular Analysis of AFP and HSA Interactions with PTEN Protein.
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| Zhu M, Lin B, Zhou P, Li M.
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| Biomed Res Int 2015:256916. doi: 10.1155/2015/256916. Epub 2015 May 20.
2015
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3 | AFP
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| Effects of AFP gene silencing on apoptosis and proliferation of a hepatocellular carcinoma cell line.
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| Zhang L, He T, Cui H, Wang Y, Huang C, Han F.
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| Discov Med 14(75):115-24.
2012
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4 | AFP
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| The effect of alpha-fetoprotein on the activation and phagocytosis of granulocytes and monocytes.
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| Kong M, Tian S, Shi H, Zhao J, Feng X, Zheng S, Duan Z, Chen Y.
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| Hepatogastroenterology 59(120):2385-8.
2012
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5 | AFP
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| Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma.
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| Wang S, Jiang W, Chen X, Zhang C, Li H, Hou W, Liu Z, McNutt MA, Lu F, Li G.
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| J Hepatol 57(2):322-9. doi: 10.1016/j.jhep.2012.03.029. Epub 2012 Apr 18.
2012
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6 | AFP
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| Autism spectrum disorders and maternal serum α-fetoprotein levels during pregnancy.
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| Abdallah MW, Grove J, Hougaard DM, Nørgaard-Pedersen B, Ibrahimov F, Mortensen EL.
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| Can J Psychiatry 56(12):727-34.
2011
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7 | AFP, LHX4
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| Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis.
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| Hung TM, Hu RH, Ho CM, Chiu YL, Lee JL, Jeng YM, Shih DT, Lee PH.
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| Carcinogenesis 32(12):1815-23. doi: 10.1093/carcin/bgr219. Epub 2011 Sep 28.
2011
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8 | AFP
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| First-trimester screening for trisomy 21 using alpha-fetoprotein.
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| Bredaki FE, Wright D, Matos P, Syngelaki A, Nicolaides KH.
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| Fetal Diagn Ther 30(3):215-8. doi: 10.1159/000330198. Epub 2011 Sep 23.
2011
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9 | AFP
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| α-Fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells.
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| Yamamoto M, Tatsumi T, Miyagi T, Tsunematsu H, Aketa H, Hosui A, Kanto T, Hiramatsu N, Hayashi N, Takehara T.
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| Clin Exp Immunol 165(2):211-9. doi: 10.1111/j.1365-2249.2011.04421.x. Epub 2011 May 19.
2011
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10 | AFP
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| Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function.
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| Setiyono A, Budiyati AD, Purwantomo S, Anggelia MR, Fanany I, Wibowo GA, Bachtiar I, Utama A, Tai S.
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| BMC Immunol 12:4. doi: 10.1186/1471-2172-12-4.
2011
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11 | AFP
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| alpha-Fetoprotein as a modulator of the pro-inflammatory response of human keratinocytes.
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| Potapovich AI, Pastore S, Kostyuk VA, Lulli D, Mariani V, De Luca C, Dudich EI, Korkina LG.
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| Br J Pharmacol 158(5):1236-47. doi: 10.1111/j.1476-5381.2009.00401.x. Epub 2009 Sep 28.
2009
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12 | AFP, ZBTB20
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| Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver.
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| Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ.
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| Proc Natl Acad Sci U S A 105(31):10859-64. Epub 2008 Jul 31.
2008
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13 | AFP, ZHX2
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| ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines.
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| Shen H, Luan F, Liu H, Gao L, Liang X, Zhang L, Sun W, Ma C.
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| J Cell Mol Med 12(6B):2772-80. doi: 10.1111/j.1582-4934.2008.00233.x. Epub 2008 Jan 11.
2008
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14 | AFP
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| Clinical value of tumor markers in gestational trophoblastic diseases.
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| Ahmad AE, Dehaghani AS, Shaker M, Fattahi MJ.
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| J Reprod Med 53(12):930-4.
2008
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15 | AFP, CEBPA
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| Identification of CCAAT enhancer binding protein alpha binding sites on the human alpha-fetoprotein gene.
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| Li HM, Ikeda H, Nakabayashi H, Nishi S, Sakai M.
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| Gene 389(2):128-35. Epub 2006 Nov 11. 2007
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16 | AFP, XIAP
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| Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
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| Dudich E, Semenkova L, Dudich I, Denesyuk A, Tatulov E, Korpela T.
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| FEBS J 273(16):3837-49. Epub 2006 Jul 26. 2006
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17 | FN1, POU5F1, MMP7, EGR1, AFP, IRX1, NR6A1
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| Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures.
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| Juric D, Sale S, Hromas RA, Yu R, Wang Y, Duran GE, Tibshirani R, Einhorn LH, Sikic BI.
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| Proc Natl Acad Sci U S A 102(49):17763-8. Epub 2005 Nov 23. 2005
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18 | AFP
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| Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription.
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| Cui R, Nguyen TT, Taube JH, Stratton SA, Feuerman MH, Barton MC.
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| J Biol Chem 280(47):39152-60. Epub 2005 Oct 2. 2005
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19 | AFP
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| Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis.
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| Yao F, Guo JM, Xu CF, Lou YL, Xiao BX, Zhou WH, Chen J, Hu YR, Liu Z, Hong GF.
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| Clin Chim Acta 361(1-2):119-27. 2005
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20 | AFP
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| Striking differences between the mouse and the human alpha-fetoprotein enhancers.
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| Long L, Davidson JN, Spear BT.
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| Genomics 83(4):694-705. 2004
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21 | AFP
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| Congenital deficiency of alpha feto-protein.
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| Sharony R, Zadik I, Parvari R.
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| Eur J Hum Genet 12(10):871-4. 2004
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22 | AFP, NKX2-8
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| Regulation of alpha-fetoprotein expression by Nkx2.8.
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| Kajiyama Y, Tian J, Locker J.
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| Mol Cell Biol 22(17):6122-30. 2002
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23 | AFP
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| Identification of an enhancer and an alternative promoter in the first intron of the alpha-fetoprotein gene.
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| Scohy S, Gabant P, Szpirer C, Szpirer J.
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| Nucleic Acids Res 28(19):3743-51. 2000
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24 | AFM, ALB, GC, AFP
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| Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster.
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| Song YH, et al.
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| Genome Res 9(6):581-7. 1999
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25 | AFM, AFP, ALB, GC
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| Genomic expansion across the albumin gene family on human chromosome 4q is directional.
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| Nishio H, Hamdi HK, Dugaiczyk A.
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| Biol Chem 380(12):1431-4. 1999
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26 | AFP
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| Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.
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| Gibbs PEM, et al.
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| Biochemistry 26 : 1332-1343. 1987
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27 | HPAFP, AFP
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| Hereditary persistence of alphafetoprotein maps to the long arm ofchromosome 4.
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| Ferguson-Smith MA, et al.
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| (HGM8) Cytogenet Cell Genet 40 : 628. 1985
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28 | AFP, ALB
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| Tandem arrangement of the albumin and alpha-fetoprotein genes in the human genome.
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| Urano Y, et al.
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| Gene 32 : 255-261. 1984
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29 | AFP
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| Human alpha-fetoprotein gene is located on chromosome 4.
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| Sakai M, et al.
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| Am J Hum Genet 35 : A151. 1983
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30 | AFP, ALB
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| Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11->22 of human chromosome 4.
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| Harper ME, et al.
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| Am J Hum Genet 35 : 565-572. 1983
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