Citations for
ZBTB20 is a sequence-specific transcriptional repressor of alpha-fetoprotein gene.
Zhang H, Cao D, Zhou L, Zhang Y, Guo X, Li H, Chen Y, Spear BT, Wu JW, Xie Z, Zhang WJ.
Sci Rep 5:11979. doi: 10.1038/srep11979. 2015
Molecular Analysis of AFP and HSA Interactions with PTEN Protein.
Zhu M, Lin B, Zhou P, Li M.
Biomed Res Int 2015:256916. doi: 10.1155/2015/256916. Epub 2015 May 20. 2015
Effects of AFP gene silencing on apoptosis and proliferation of a hepatocellular carcinoma cell line.
Zhang L, He T, Cui H, Wang Y, Huang C, Han F.
Discov Med 14(75):115-24. 2012
The effect of alpha-fetoprotein on the activation and phagocytosis of granulocytes and monocytes.
Kong M, Tian S, Shi H, Zhao J, Feng X, Zheng S, Duan Z, Chen Y.
Hepatogastroenterology 59(120):2385-8. 2012
Alpha-fetoprotein acts as a novel signal molecule and mediates transcription of Fn14 in human hepatocellular carcinoma.
Wang S, Jiang W, Chen X, Zhang C, Li H, Hou W, Liu Z, McNutt MA, Lu F, Li G.
J Hepatol 57(2):322-9. doi: 10.1016/j.jhep.2012.03.029. Epub 2012 Apr 18. 2012
Autism spectrum disorders and maternal serum α-fetoprotein levels during pregnancy.
Abdallah MW, Grove J, Hougaard DM, Nørgaard-Pedersen B, Ibrahimov F, Mortensen EL.
Can J Psychiatry 56(12):727-34. 2011
Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis.
Hung TM, Hu RH, Ho CM, Chiu YL, Lee JL, Jeng YM, Shih DT, Lee PH.
Carcinogenesis 32(12):1815-23. doi: 10.1093/carcin/bgr219. Epub 2011 Sep 28. 2011
First-trimester screening for trisomy 21 using alpha-fetoprotein.
Bredaki FE, Wright D, Matos P, Syngelaki A, Nicolaides KH.
Fetal Diagn Ther 30(3):215-8. doi: 10.1159/000330198. Epub 2011 Sep 23. 2011
α-Fetoprotein impairs activation of natural killer cells by inhibiting the function of dendritic cells.
Yamamoto M, Tatsumi T, Miyagi T, Tsunematsu H, Aketa H, Hosui A, Kanto T, Hiramatsu N, Hayashi N, Takehara T.
Clin Exp Immunol 165(2):211-9. doi: 10.1111/j.1365-2249.2011.04421.x. Epub 2011 May 19. 2011
Immunoregulatory effects of AFP domains on monocyte-derived dendritic cell function.
Setiyono A, Budiyati AD, Purwantomo S, Anggelia MR, Fanany I, Wibowo GA, Bachtiar I, Utama A, Tai S.
BMC Immunol 12:4. doi: 10.1186/1471-2172-12-4. 2011
alpha-Fetoprotein as a modulator of the pro-inflammatory response of human keratinocytes.
Potapovich AI, Pastore S, Kostyuk VA, Lulli D, Mariani V, De Luca C, Dudich EI, Korkina LG.
Br J Pharmacol 158(5):1236-47. doi: 10.1111/j.1476-5381.2009.00401.x. Epub 2009 Sep 28. 2009
Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver.
Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ.
Proc Natl Acad Sci U S A 105(31):10859-64. Epub 2008 Jul 31. 2008
ZHX2 is a repressor of alpha-fetoprotein expression in human hepatoma cell lines.
Shen H, Luan F, Liu H, Gao L, Liang X, Zhang L, Sun W, Ma C.
J Cell Mol Med 12(6B):2772-80. doi: 10.1111/j.1582-4934.2008.00233.x. Epub 2008 Jan 11. 2008
Clinical value of tumor markers in gestational trophoblastic diseases.
Ahmad AE, Dehaghani AS, Shaker M, Fattahi MJ.
J Reprod Med 53(12):930-4. 2008
Identification of CCAAT enhancer binding protein alpha binding sites on the human alpha-fetoprotein gene.
Li HM, Ikeda H, Nakabayashi H, Nishi S, Sakai M.
Gene 389(2):128-35. Epub 2006 Nov 11. 2007
Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
Dudich E, Semenkova L, Dudich I, Denesyuk A, Tatulov E, Korpela T.
FEBS J 273(16):3837-49. Epub 2006 Jul 26. 2006
17FN1, POU5F1, MMP7, EGR1, AFP, IRX1, NR6A1
Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures.
Juric D, Sale S, Hromas RA, Yu R, Wang Y, Duran GE, Tibshirani R, Einhorn LH, Sikic BI.
Proc Natl Acad Sci U S A 102(49):17763-8. Epub 2005 Nov 23. 2005
Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription.
Cui R, Nguyen TT, Taube JH, Stratton SA, Feuerman MH, Barton MC.
J Biol Chem 280(47):39152-60. Epub 2005 Oct 2. 2005
Detecting AFP mRNA in peripheral blood of the patients with hepatocellular carcinoma, liver cirrhosis and hepatitis.
Yao F, Guo JM, Xu CF, Lou YL, Xiao BX, Zhou WH, Chen J, Hu YR, Liu Z, Hong GF.
Clin Chim Acta 361(1-2):119-27. 2005
Striking differences between the mouse and the human alpha-fetoprotein enhancers.
Long L, Davidson JN, Spear BT.
Genomics 83(4):694-705. 2004
Congenital deficiency of alpha feto-protein.
Sharony R, Zadik I, Parvari R.
Eur J Hum Genet 12(10):871-4. 2004
22AFP, NKX2-8
Regulation of alpha-fetoprotein expression by Nkx2.8.
Kajiyama Y, Tian J, Locker J.
Mol Cell Biol 22(17):6122-30. 2002
Identification of an enhancer and an alternative promoter in the first intron of the alpha-fetoprotein gene.
Scohy S, Gabant P, Szpirer C, Szpirer J.
Nucleic Acids Res 28(19):3743-51. 2000
Physical and meiotic mapping of the region of human chromosome 4q11-q13 encompassing the vitamin D binding protein DBP/Gc-globulin and albumin multigene cluster.
Song YH, et al.
Genome Res 9(6):581-7. 1999
Genomic expansion across the albumin gene family on human chromosome 4q is directional.
Nishio H, Hamdi HK, Dugaiczyk A.
Biol Chem 380(12):1431-4. 1999
Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.
Gibbs PEM, et al.
Biochemistry 26 : 1332-1343. 1987
Hereditary persistence of alphafetoprotein maps to the long arm ofchromosome 4.
Ferguson-Smith MA, et al.
(HGM8) Cytogenet Cell Genet 40 : 628. 1985
Tandem arrangement of the albumin and alpha-fetoprotein genes in the human genome.
Urano Y, et al.
Gene 32 : 255-261. 1984
Human alpha-fetoprotein gene is located on chromosome 4.
Sakai M, et al.
Am J Hum Genet 35 : A151. 1983
Linkage of the evolutionarily-related serum albumin and alpha-fetoprotein genes within q11->22 of human chromosome 4.
Harper ME, et al.
Am J Hum Genet 35 : 565-572. 1983