| 1 | AFF1, AFF4
|
| Structure of the super-elongation complex subunit AFF4 C-terminal homology domain reveals requirements for AFF homo- and heterodimerization.
|
| Chen Y, Cramer P.
|
| J Biol Chem. Jul 5;294(27):10663-10673. doi: 10.1074/jbc.RA119.008577. Epub 2019 May 30 2019
|
| 2 | AFF1, AFF4, DKK1
|
| AFF1 and AFF4 differentially regulate the osteogenic differentiation of human MSCs.
|
| Zhou CC, Xiong QC, Zhu XX, Du W, Deng P, Li XB, Jiang YZ, Zou SJ, Wang CY, Yuan Q.
|
| Bone Res. Sep 26;5:17044. doi: 10.1038/boneres.2017.44. eCollection 2017. 2017
|
| 3 | AFF1, AFF2, AFF3, AFF4
|
| Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.
|
| Melko M, Douguet D, Bensaid M, Zongaro S, Verheggen C, Gecz J, Bardoni B.
|
| Hum Mol Genet 20(10):1873-85. Epub 2011 Feb 17.
2011
|
| 4 | AFF1, AFF4
|
| A higher-order complex containing AF4 and ENL family proteins with P-TEFb facilitates oncogenic and physiologic MLL-dependent transcription.
|
| Yokoyama A, Lin M, Naresh A, Kitabayashi I, Cleary ML.
|
| Cancer Cell 17(2):198-212. 2010
|
| 5 | AFF4
|
| MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription.
|
| Niedzielski MF, Hopewell R, Ismail Z, Estable MC.
|
| Int J Biol Sci 3(4):225-36.
2007
|
| 6 | AFF4
|
| The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling.
|
| Bitoun E, Oliver PL, Davies KE.
|
| Hum Mol Genet 16(1):92-106. Epub 2006 Nov 29.
2007
|
| 7 | AFF4
|
| The eleven-nineteen-leukemia protein ENL connects nuclear MLL fusion partners with chromatin.
|
| Zeisig DT, Bittner CB, Zeisig BB, García-Cuéllar MP, Hess JL, Slany RK.
|
| Oncogene 24(35):5525-32.
2005
|
| 8 | AFF4, KMT2A
|
| Insertion of MLL sequences into chromosome band 5q31 results in an MLL-AF5Q31 fusion and is a rare but recurrent abnormality associated with infant leukemia.
|
| Deveney R, Chervinsky DS, Jani-Sait SN, Grossi M, Aplan PD.
|
| Genes Chromosomes Cancer 37(3):326-31. 2003
|
| 9 | AFF4, EAF1, AFF2, AFF1
|
| FMR2 function: insight from a mouse knockout model.
|
| Gu Y, Nelson DL.
|
| Cytogenet Genome Res 100(1-4):129-39. 2003
|
| 10 | AFF4
|
| MCEF, the newest member of the AF4 family of transcription factors involved in leukemia, is a positive transcription elongation factor-b-associated protein.
|
| Estable MC, Naghavi MH, Kato H, Xiao H, Qin J, Vahlne A, Roeder RG.
|
| J Biomed Sci 9(3):234-45. 2002
|
| 11 | AFF4
|
| AF5q31, a newly identified AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia with ins(5;11)(q31;q13q23).
|
| Taki T, Kano H, Taniwaki M, Sako M, Yanagisawa M, Hayashi Y.
|
| Proc Natl Acad Sci U S A 96(25):14535-40 1999
|
| 12 | AFF4, ARAP3, CCNL1, FACLL, IL5, IRF1, KIF3A, P4HA2, PDLIM4, RAD50, SEPTIN8, SHROOM1
|
| Computational and biological analysis of 680 kb of DNA sequence from the human 5q31 cytokine gene cluster region.
|
| Frazer KA, Ueda Y, Zhu Y, Gifford VR, Garofalo MR, Mohandas N, Martin CH, Palazzolo MJ, Cheng JF, Rubin EM.
|
| Genome Res 7 : 495-512. 1997
|
| 13 | AFF1, AFF4
|
| AF4/FEL, a gene involved in infant leukemia : sequence variations, gene structure, and possible homology with a genomic sequence on 5q31.
|
| Frestedt JL, et al.
|
| DNA Cell Biol 15 : 669-678. 1996
|