| 1 | ADRB1, ADRB2, ADRB3
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| Differential S-palmitoylation of the human and rodent β3-adrenergic receptor.
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| Adachi N, Hess DT, Kaku M, Ueda C, Numa C, Saito N.
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| J Biol Chem Biol Chem. 2018 Dec 12. pii: jbc.RA118.004978. doi: 10.1074/jbc.RA118.004978. [Epub ahead of print]
2018
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| 2 | ADRB2, NEDD4, USP20, USP33
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| Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress.
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| Kommaddi RP, Jean-Charles PY, Shenoy SK.
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| J Biol Chem 290(14):8888-903. doi: 10.1074/jbc.M114.630541. Epub 2015 Feb 9.
2015
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| 3 | ADRB1, ADRB2, SSTR2
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| Somatostatin receptor-2 negatively regulates β-adrenergic receptor mediated Ca(2+) dependent signaling pathways in H9c2 cells.
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| Somvanshi RK, Zou S, Qiu X, Kumar U.
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| Biochim Biophys Acta 1843(4):735-45. doi: 10.1016/j.bbamcr.2014.01.002. Epub 2014 Jan 9.
2014
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| 4 | ADRB1, ADRB2
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| β1-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations.
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| Rössler J, Haubold M, Gilsbach R, Jüttner E, Schmitt D, Niemeyer CM, Hein L.
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| Pediatr Res 73(4 Pt 1):409-13. doi: 10.1038/pr.2013.16. Epub 2013 Jan 31.
2013
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| 5 | ADRB2, IFNA1, TLR9
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| Beta2-adrenoceptor stimulation suppresses TLR9-dependent IFNA1 secretion in human peripheral blood mononuclear cells.
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| Hilbert T, Bongartz J, Weisheit C, Knüfermann P, Baumgarten G, Hoeft A, Poth JM.
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| PLoS One 8(5):e65024. doi: 10.1371/journal.pone.0065024. Print 2013.
2013
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| 6 | ADRB1, ADRB2
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| Deletion of β-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation.
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| Pierroz DD, Bonnet N, Bianchi EN, Bouxsein ML, Baldock PA, Rizzoli R, Ferrari SL.
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| J Bone Miner Res 27(6):1252-62. doi: 10.1002/jbmr.1594.
2012
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| 7 | ADRB2, FOLR3, GSTM1
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| Monocyte gene expression signature of patients with early onset coronary artery disease.
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| Sivapalaratnam S, Basart H, Watkins NA, Maiwald S, Rendon A, Krishnan U, Sondermeijer BM, Creemers EE, Pinto-Sietsma SJ, Hovingh K, Ouwehand WH, Kastelein JJ, Goodall AH, Trip MD.
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| PLoS One 7(2):e32166. doi: 10.1371/journal.pone.0032166. Epub 2012 Feb 21.
2012
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| 8 | ADRB2, MARCHF2
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| MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors.
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| Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK.
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| J Cell Biol 199(5):817-30. doi: 10.1083/jcb.201208192. Epub 2012 Nov 19. 2012
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| 9 | ADRB2
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| ADRB2 haplotype is associated with glucose tolerance and insulin sensitivity in obese postmenopausal women.
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| Prior SJ, Goldberg AP, Ryan AS.
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| Obesity (Silver Spring) 19(2):396-401. Epub 2010 Sep 9.
2011
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| 10 | ADRB2
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| Promoter polymorphisms in the β-2 adrenergic receptor are associated with drug-induced gene expression changes and response in acute lymphoblastic leukemia.
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| Pottier N, Paugh SW, Ding C, Pei D, Yang W, Das S, Cook EH, Pui CH, Relling MV, Cheok MH, Evans WE.
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| Clin Pharmacol Ther 88(6):854-61. Epub 2010 Oct 27.
2010
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| 11 | ADRB2
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| Attenuation of beta2-adrenergic receptors and homocysteine metabolic enzymes cause diabetic cardiomyopathy.
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| Mishra PK, Givvimani S, Metreveli N, Tyagi SC.
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| Biochem Biophys Res Commun 401(2):175-81. Epub 2010 Sep 15.
2010
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| 12 | ADRB2
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| beta2-Adrenoceptor confers cardioprotection against hypoxia in isolated ventricular myocytes and the effects depend on estrogenic environment.
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| Xu C, Liu A, Sun H, Sun Y, Wang G, Gao L, Hao Y, Yan C.
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| J Recept Signal Transduct Res 30(4):255-61.
2010
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| 13 | ADRB2
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| Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.
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| Nikolaev VO, Moshkov A, Lyon AR, Miragoli M, Novak P, Paur H, Lohse MJ, Korchev YE, Harding SE, Gorelik J.
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| Science 327(5973):1653-7. Epub 2010 Feb 25.
2010
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| 14 | ADRB2, ADRB3
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| beta2- and beta3-, but not beta1-adrenergic receptors are involved in osteogenesis of mouse mesenchymal stem cells via cAMP/PKA signaling.
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| Li H, Fong C, Chen Y, Cai G, Yang M.
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| Arch Biochem Biophys 496(2):77-83. doi: 10.1016/j.abb.2010.01.016. Epub 2010 Feb 4.
2010
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| 15 | ADRB2
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| Vascular smooth muscle cell-selective peroxisome proliferator-activated receptor-gamma deletion leads to hypotension.
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| Chang L, Villacorta L, Zhang J, Garcia-Barrio MT, Yang K, Hamblin M, Whitesall SE, D'Alecy LG, Chen YE.
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| Circulation 119(16):2161-9. Epub 2009 Apr 13.
2009
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| 16 | ADRA1B, ADRB2
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| Functional alpha1- and beta2-adrenergic receptors in human osteoblasts.
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| Huang HH, Brennan TC, Muir MM, Mason RS.
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| J Cell Physiol 220(1):267-75.
2009
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| 17 | ADRB2
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| Polymorphisms of the beta2 adrenoreceptor gene in chronic obstructive pulmonary disease.
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| Vacca G, Schwabe K, Dück R, Hlawa HP, Westphal A, Pabst S, Grohé C, Gillissen A.
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| Ther Adv Respir Dis 3(1):3-10.
2009
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| 18 | ADRB2
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| Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model.
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| Nguyen LP, Lin R, Parra S, Omoluabi O, Hanania NA, Tuvim MJ, Knoll BJ, Dickey BF, Bond RA.
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| Proc Natl Acad Sci U S A 106(7):2435-40. Epub 2009 Jan 26.
2009
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| 19 | ADRB2
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| Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization.
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| Krasel C, Zabel U, Lorenz K, Reiner S, Al-Sabah S, Lohse MJ.
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| J Biol Chem 283(46):31840-8. Epub 2008 Sep 18.
2008
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| 20 | ADRB2, NEDD4
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| Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor.
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| Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM.
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| J Biol Chem 283(32):22166-76. Epub 2008 Jun 10.
2008
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| 21 | ADRB1, ADRB2
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| Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.
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| Inagaki Y, Mashima Y, Fuse N, Funayama T, Ohtake Y, Yasuda N, Murakami A, Hotta Y, Fukuchi T, Tsubota K.
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| Mol Vis 12:673-80. 2006
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| 22 | ADRB3, GNB3, ADRB2
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| Impact of variation in ADRB2, ADRB3, and GNB3 genes on body mass index and waist circumference in a Brazilian population.
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| Mattevi VS, Zembrzuski VM, Hutz MH.
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| Am J Hum Biol 18(2):182-6. 2006
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| 23 | ADRB2,UCP3
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| Beta2-adrenergic receptor and UCP3 variants modulate the relationship between age and type 2 diabetes mellitus.
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| Pinelli M, Giacchetti M, Acquaviva F, Cocozza S, Donnarumma G, Lapice E, Riccardi G, Romano G, Vaccaro O, Monticelli A.
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| BMC Med Genet 7:85. 2006
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| 24 | ADRB2, ADRB3, UCP1
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| Common variants in beta2- and beta3-adrenergic receptor genes and uncoupling protein 1 as predictors of the risk for type 2 diabetes and body weight changes. The Finnish Diabetes Prevention Study.
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| Salopuro T, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne-Parikka P, Keinanen-Kiukaanniemi S, Tuomilehto J, Laakso M, Uusitupa M.
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| Clin Genet 66(4):365-7. No abstract available. 2004
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| 25 | ADRB1, ADRB2
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| The PDZ-binding motif of the beta2-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes.
|
| Xiang Y, Kobilka B.
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| Proc Natl Acad Sci U S A 100(19):10776-81. Epub 2003 Sep 03. 2003
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| 26 | ADRB2
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| The 27Glu polymorphism of the beta2-adrenergic receptor gene interacts with physical activity influencing obesity risk among female subjects.
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| No authors listed
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| Clin Genet 61(4):305-307. No abstract available. 2002
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| 27 | ADRB2
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| beta-2 adrenoceptor genetic variation is associated with genetic predisposition to essential hypertension : the Bergen blood pressure study.
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| Timmermann B, et al.
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| Kidney Int 53 : 1455-1460. 1998
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| 28 | ADRB2
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| Polymorphisms of the 5' leader cistron of the human beta2-adrenergic receptor regulate receptor expression.
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| McGraw DW, et al.
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| J Clin Invest 102 : 1927-1932. 1998
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| 29 | ADRB2, GM2A
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| Novel genes mapping to the critical region of the 5q-syndrome.
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| Boultwood J, Fidler C, Soularue P, Strickson AJ, Kostrzewa M, Jaju RJ, Cotter FE, Fairweather N, Monaco AP, Muller U, Lovett M, Jabs EW, Auffray C, Wainscoat JS.
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| Genomics 45(1):88-96. 1997
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| 30 | ADRB2
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| Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.
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| Large V, Hellstrom L, Reynisdottir S, Lonnqvist F, Eriksson P, Lannfelt L, Arner P.
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| J Clin Invest 100(12):3005-13. 1997
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| 31 | ADRB2
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| Polymorphism in the human beta2 adrenergic receptor gene detected by restriction endonuclease digestion with Fnu4HI.
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| McQuitty CK, et al.
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| Hum Genet 93 : 225. 1994
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| 32 | ADRA1A, ADRB2, ADRA1B
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| Genes encoding adrenergic receptors are not clustered on the long arm of human chromosome 5.
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| Loftus SK, et al.
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| Cytogenet Cell Genet 67 : 69-74. 1994
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| 33 | ADRB2
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| Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties.
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| Green SA, et al.
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| Biochemistry 33 : 9414-9419. 1994
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| 34 | ADRB2
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| The peptide product of a 5' leader cistron in the beta 2 adrenergic receptor mRNA inhibits receptor synthesis.
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| Parola AL, et al.
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| J Biol Chem 269 : 4497-4505. 1994
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| 35 | CSF1R, ADRB2
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| A physical map of 15 loci on human chromosome 5q23-q33 by two-color fluorescence in situ hybridization.
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| Saltman DL, et al.
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| Genomics 16 : 726-732. 1993
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| 36 | ADRB2, CD14, CSF1R, FGF1, GABRA1, IL3, IL9, GABRG2
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| A radiation hybrid map of 18 growth factor , growth factor receptor, hormone receptor, or neurotransmitter receptor genes on the distal region of the long arm of chromosome 5.
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| Warrington JA, et al.
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| Genomics 13 : 803-808. 1992
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| 37 | ADRB1, ADRA2C, ADRA2A, ADRB2
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| Genetic mapping of adrenergic receptor genes.
|
| Hoehe M, et al.
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| Am J Hum Genet 45 : A143. 1989
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| 38 | ADRB2
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| A biallelic DNA polymorphism of the human beta-2-adrenergic receptor detected by Ban I-Adrbr-2.
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| Lentes KU, et al.
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| Nucleic Acids Res 16 : 2359. 1988
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| 39 | ADRB2
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| cDNA for the human beta2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
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| Kobilka BK, et al.
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| Proc Natl Acad Sci U S A 84 : 46-50. 1987
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| 40 | ADRB2
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| Cloning and sequence analysis of the human brain beta-adrenergic receptor. Evolutionary relationship to rodent and avian beta-receptors and porcine muscarinic receptors.
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| Chung FZ, et al.
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| FEBS Lett 211 :200-206. 1987
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| 41 | ADRB2
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| Delineation of the intronless nature of the genes for the human and hamster beta-2-adrenergic receptor and their putative promoter regions.
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| Kobilka BK, et al.
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| J Biol Chem 262 : 7321-7327. 1987
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| 42 | ADRB2
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| Chromosomal assignment of the gene for the human beta-2-adrenergic receptor.
|
| Sheppard JR, et al.
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| Proc Natl Acad Sci U S A 80 : 233-236. 1983
|