1 | ADRB1, ADRB2, ADRB3
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| Differential S-palmitoylation of the human and rodent β3-adrenergic receptor.
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| Adachi N, Hess DT, Kaku M, Ueda C, Numa C, Saito N.
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| J Biol Chem Biol Chem. 2018 Dec 12. pii: jbc.RA118.004978. doi: 10.1074/jbc.RA118.004978. [Epub ahead of print]
2018
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2 | ADRB1, GOPC, SNX1
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| The golgi-associated PDZ domain protein PIST/GOPC stabilizes the β1-adrenergic receptor in intracellular compartments after internalization.
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| Koliwer J, Park M, Bauch C, von Zastrow M, Kreienkamp HJ.
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| J Biol Chem 290(10):6120-9. doi: 10.1074/jbc.M114.605725. Epub 2015 Jan 22.
2015
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3 | ADRB1, PTGS2
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| β1-Adrenergic receptor downregulates the expression of cyclooxygenase-2.
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| Brender S, Barki-Harrington L.
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| Biochem Biophys Res Commun 451(2):319-21. doi: 10.1016/j.bbrc.2014.07.123. Epub 2014 Aug 1.
2014
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4 | ADRB1, TRPV5
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| β1-Adrenergic receptor signaling activates the epithelial calcium channel, transient receptor potential vanilloid type 5 (TRPV5), via the protein kinase A pathway.
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| van der Hagen EA, Tudpor K, Verkaart S, Lavrijsen M, van der Kemp A, van Zeeland F, Bindels RJ, Hoenderop JG.
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| J Biol Chem 289(26):18489-96. doi: 10.1074/jbc.M113.491274. Epub 2014 May 14.
2014
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5 | ADRB1, DLG1, PDE4D
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| A long lasting β1 adrenergic receptor stimulation of cAMP/protein kinase A (PKA) signal in cardiac myocytes.
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| Fu Q, Kim S, Soto D, De Arcangelis V, DiPilato L, Liu S, Xu B, Shi Q, Zhang J, Xiang YK.
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| J Biol Chem 289(21):14771-81. doi: 10.1074/jbc.M113.542589. Epub 2014 Apr 8.
2014
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6 | ADRB1, ADRB2, SSTR2
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| Somatostatin receptor-2 negatively regulates β-adrenergic receptor mediated Ca(2+) dependent signaling pathways in H9c2 cells.
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| Somvanshi RK, Zou S, Qiu X, Kumar U.
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| Biochim Biophys Acta 1843(4):735-45. doi: 10.1016/j.bbamcr.2014.01.002. Epub 2014 Jan 9.
2014
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7 | ADRB1, ADRB3
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| Differential expression and role of hyperglycemia induced oxidative stress in epigenetic regulation of β1, β2 and β3-adrenergic receptors in retinal endothelial cells.
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| Safi SZ, Qvist R, Yan GO, Ismail IS.
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| BMC Med Genomics 7:29. doi: 10.1186/1755-8794-7-29.
2014
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8 | ADRB1, AKAP5
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| Role of AKAP79/150 protein in β1-adrenergic receptor trafficking and signaling in mammalian cells.
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| Li X, Nooh MM, Bahouth SW.
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| J Biol Chem 288(47):33797-812. doi: 10.1074/jbc.M113.470559. Epub 2013 Oct 11.
2013
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9 | ADRB1, SNX27
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| β1-adrenergic receptor recycles via a membranous organelle, recycling endosome, by binding with sorting nexin27.
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| Nakagawa T, Asahi M.
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| J Membr Biol 246(7):571-9. doi: 10.1007/s00232-013-9571-6. Epub 2013 Jun 19.
2013
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10 | ADRB1, AKAP5, DLG1
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| SAP97 controls the trafficking and resensitization of the beta-1-adrenergic receptor through its PDZ2 and I3 domains.
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| Nooh MM, Naren AP, Kim SJ, Xiang YK, Bahouth SW.
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| PLoS One 8(5):e63379. doi: 10.1371/journal.pone.0063379. Print 2013.
2013
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11 | ADRB1, ADRB2
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| β1-Adrenoceptor mRNA level reveals distinctions between infantile hemangioma and vascular malformations.
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| Rössler J, Haubold M, Gilsbach R, Jüttner E, Schmitt D, Niemeyer CM, Hein L.
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| Pediatr Res 73(4 Pt 1):409-13. doi: 10.1038/pr.2013.16. Epub 2013 Jan 31.
2013
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12 | ADRB1, ADRB2
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| Deletion of β-adrenergic receptor 1, 2, or both leads to different bone phenotypes and response to mechanical stimulation.
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| Pierroz DD, Bonnet N, Bianchi EN, Bouxsein ML, Baldock PA, Rizzoli R, Ferrari SL.
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| J Bone Miner Res 27(6):1252-62. doi: 10.1002/jbmr.1594.
2012
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13 | ADRB1
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| Trans-Golgi Network (TGN) as a regulatory node for β1-adrenergic receptor (β1AR) down-modulation and recycling.
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| Cheng SB, Filardo EJ.
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| J Biol Chem 287(17):14178-91. doi: 10.1074/jbc.M111.323782. Epub 2012 Feb 29.
2012
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14 | ADRB1
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| Analysis of beta1 and beta2-adrenergic receptors polymorphism in patients with apical ballooning cardiomyopathy.
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| Vriz O, Minisini R, Citro R, Guerra V, Zito C, De Luca G, Pavan D, Pirisi M, Limongelli G, Bossone E.
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| Acta Cardiol 66(6):787-90.
2011
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15 | ADRB1
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| Induced loss of ADAR2 engenders slow death of motor neurons from Q/R site-unedited GluR2.
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| Hideyama T, Yamashita T, Suzuki T, Tsuji S, Higuchi M, Seeburg PH, Takahashi R, Misawa H, Kwak S.
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| J Neurosci 30(36):11917-25.
2010
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16 | ADRB1
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| Human beta1-adrenergic receptor is subject to constitutive and regulated N-terminal cleavage.
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| Hakalahti AE, Vierimaa MM, Lilja MK, Kumpula EP, Tuusa JT, Petäjä-Repo UE.
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| J Biol Chem 285(37):28850-61. doi: 10.1074/jbc.M110.149989. Epub 2010 Jun 29.
2010
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17 | ADRB1
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| Association of ADRB1 gene polymorphism with atrial fibrillation.
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| Nicoulina S, Shulman V, Shesternya P, Chernova A, Salmina A, Issachenko O, Maksimov V, Voevoda M.
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| Genet Test Mol Biomarkers 14(2):249-53. doi: 10.1089/gtmb.2009.0100.
2010
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18 | ADRB1
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| Functional rescue of beta-adrenoceptor dimerization and trafficking by pharmacological chaperones.
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| Kobayashi H, Ogawa K, Yao R, Lichtarge O, Bouvier M.
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| Traffic 10(8):1019-33. doi: 10.1111/j.1600-0854.2009.00932.x. Epub 2009 Jun 9.
2009
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19 | ADRB1, ADRB2
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| Polymorphism of beta-adrenergic receptors and susceptibility to open-angle glaucoma.
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| Inagaki Y, Mashima Y, Fuse N, Funayama T, Ohtake Y, Yasuda N, Murakami A, Hotta Y, Fukuchi T, Tsubota K.
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| Mol Vis 12:673-80. 2006
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20 | ADRB1, GOLGA3
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| Golgin-160 promotes cell surface expression of the beta-1 adrenergic receptor.
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| Hicks SW, Horn TA, McCaffery JM, Zuckerman DM, Machamer CE.
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| Traffic 7(12):1666-77.
2006
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21 | ADRB1, ADRB2
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| The PDZ-binding motif of the beta2-adrenoceptor is essential for physiologic signaling and trafficking in cardiac myocytes.
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| Xiang Y, Kobilka B.
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| Proc Natl Acad Sci U S A 100(19):10776-81. Epub 2003 Sep 03. 2003
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22 | ADRB1
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| Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.
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| Mialet Perez J, Rathz DA, Petrashevskaya NN, Hahn HS, Wagoner LE, Schwartz A, Dorn GW, Liggett SB.
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| Nat Med 9(10):1300-5. Epub 2003 Sep 14. 2003
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23 | ADRB1, ADRBK1
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| Clathrin box in G protein-coupled receptor kinase 2.
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| Shiina T, Arai K, Tanabe S, Yoshida N, Haga T, Nagao T, Kurose H.
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| J Biol Chem 276(35):33019-26. 2001
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24 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
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| Sequence diversity in 36 candidate genes for cardiovascular disorders.
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| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
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| Am J Hum Genet 65(1):183-91. 1999
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25 | ADRB1
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| A gain-of-function polymorphism in a G-protein coupling domain of the human beta1-adrenergic receptor.
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| Mason DA, et al.
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| J Biol Chem 274(18):12670-4. 1999
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26 | ADRB1
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| Characterization of a unique genetic variant in the beta1-adrenoceptor gene and evaluation of its role in idiopathic dilated cardiomyopathy. CARDIGENE Group.
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| Tesson F, et al.
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| J Mol Cell Cardiol 31(5):1025-32. 1999
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27 | ADRB1
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| Characterization of two human beta1-adrenergic receptor transcripts: cloning and alterations in the failing heart.
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| Ellis CE, et al.
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| Biochem Biophys Res Commun 258(3):552-8. 1999
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28 | ADRA1A, ADRA1B, ADRB1
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| Chromosomal organization of adrenergic receptor genes.
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| Yang-Feng TL, et al.
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| Proc Natl Acad Sci U S A 87 : 1516-1520. 1990
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29 | ICAM1, ADRB1
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| The major human rhinovirus receptor is ICAM-1.
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| Greve JM, et al.
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| Cell 56 : 839-847. 1989
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30 | ADRB1, ADRA2C, ADRA2A, ADRB2
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| Genetic mapping of adrenergic receptor genes.
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| Hoehe M, et al.
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| Am J Hum Genet 45 : A143. 1989
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