1 | ADM, AGTRAP, ALOX5, ENTPD1, IRAK3, MMP9, S100A8
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| Identification of key pathogenic genes of sepsis based on the Gene Expression Omnibus database.
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| Lu X, Xue L, Sun W, Ye J, Zhu Z, Mei H.
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| Mol Med Rep. Feb;17(2):3042-3054. doi: 10.3892/mmr.2017.8258. Epub 2017 Dec 12 2018
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2 | ADM, RAMP2
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| Adrenomedullin-RAMP2 system suppresses ER stress-induced tubule cell death and is involved in kidney protection.
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| Uetake R, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Kawate H, Iesato Y, Yoshizawa T, Koyama T, Yang L, Toriyama Y, Yamauchi A, Igarashi K, Tanaka M, Kuwabara T, Mori K, Yanagita M, Mukoyama M, Shindo T.
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| PLoS One 9(2):e87667. doi: 10.1371/journal.pone.0087667. eCollection 2014.
2014
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3 | ADM, CALCRL, RAMP2, RAMP3
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| Adrenomedullin expression in the developing human fetal lung.
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| Ramos CG, Sun X, Johnson EB, Nelson HE, Gonzalez Bosc LV.
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| J Investig Med 62(1):49-55. doi: 10.231/JIM.0000000000000020. 2014
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4 | ADM
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| Is the Cytoskeleton an Intracellular Receptor for Adrenomedullin and PAMP?
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| Larráyoz IM, Martínez-Herrero S, Ochoa-Callejero L, García-Sanmartín J, Martínez A.
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| Curr Protein Pept Sci urr Protein Pept Sci. 2013 Jun 5. [Epub ahead of print]
2013
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5 | ADM
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| Roles of CLR/RAMP Receptor Signaling in Reproduction and Development.
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| Chang CL, Hsu SY.
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| Curr Protein Pept Sci urr Protein Pept Sci. 2013 Jun 5. [Epub ahead of print]
2013
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6 | ADM
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| Adrenomedullin in Cardiovascular Disease: A Useful Biomarker, Its Pathological Roles and Therapeutic Application.
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| Nishikimi T, Kuwahara K, Nakagawa Y, Kangawa K, Nakao K.
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| Curr Protein Pept Sci urr Protein Pept Sci. 2013 Jun 4. [Epub ahead of print]
2013
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7 | ADM
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| Adrenomedullin as a Potential Therapeutic Agent for Inflammatory Bowel Disease.
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| Ashizuka S, Inatsu H, Inagaki-Ohara K, Kita T, Kita T, Kitamura K.
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| Curr Protein Pept Sci urr Protein Pept Sci. 2013 Jun 4. [Epub ahead of print]
2013
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8 | ADM
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| Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta.
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| Li M, Schwerbrock NM, Lenhart PM, Fritz-Six KL, Kadmiel M, Christine KS, Kraus DM, Espenschied ST, Willcockson HH, Mack CP, Caron KM.
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| J Clin Invest 123(6):2408-20. doi: 10.1172/JCI67039. Epub 2013 May 1.
2013
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9 | ADM
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| The hypoxia target adrenomedullin is aberrantly expressed in multiple myeloma and promotes angiogenesis.
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| Kocemba KA, van Andel H, de Haan-Kramer A, Mahtouk K, Versteeg R, Kersten MJ, Spaargaren M, Pals ST.
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| Leukemia eukemia. 2013 Mar 12. doi: 10.1038/leu.2013.76. [Epub ahead of print]
2013
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10 | ADM, TNF
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| Serum levels of adrenomedullin and inflammatory cytokines in women with term idiopathic intrauterine growth restriction.
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| Elfayomy AK, Habib FA, Almasry SM, Safwat MD, Eldomiaty MA.
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| J Obstet Gynaecol 33(2):135-9. doi: 10.3109/01443615.2012.721821.
2013
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11 | ADM, RAMP2
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| Vascular endothelial adrenomedullin-RAMP2 system is essential for vascular integrity and organ homeostasis.
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| Koyama T, Ochoa-Callejero L, Sakurai T, Kamiyoshi A, Ichikawa-Shindo Y, Iinuma N, Arai T, Yoshizawa T, Iesato Y, Lei Y, Uetake R, Okimura A, Yamauchi A, Tanaka M, Igarashi K, Toriyama Y, Kawate H, Adams RH, Kawakami H, Mochizuki N, Martínez A, Shindo T.
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| Circulation 127(7):842-53. doi: 10.1161/CIRCULATIONAHA.112.000756. Epub 2013 Jan 25.
2013
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12 | ADM
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| Pro-adrenomedullin as a novel biomarker for predicting infections and response to antimicrobials in febrile patients with hematologic malignancies.
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| Al Shuaibi M, Bahu RR, Chaftari AM, Al Wohoush I, Shomali W, Jiang Y, Debiane L, Raad S, Jabbour J, Al Akhrass F, Hachem RY, Raad I.
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| Clin Infect Dis 56(7):943-50. doi: 10.1093/cid/cis1029. Epub 2013 Jan 3.
2013
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13 | ADM
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| Evidence for a functional adrenomedullin signaling pathway in the mouse retina.
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| Blom J, Giove TJ, Pong WW, Blute TA, Eldred WD.
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| Mol Vis 18:1339-53. Epub 2012 May 30.
2012
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14 | ADM
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| Adrenomedullin inhibits choroidal neovascularization via CCL2 in the retinal pigment epithelium.
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| Yuda K, Takahashi H, Inoue T, Ueta T, Iriyama A, Kadonosono K, Tamaki Y, Aburatani H, Nagai R, Yanagi Y.
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| Am J Pathol 181(4):1464-72. doi: 10.1016/j.ajpath.2012.06.028. Epub 2012 Jul 27.
2012
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15 | ADM, CFH
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| The critical role of adrenomedullin and its binding protein, AMBP-1, in neuroprotection.
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| Cheyuo C, Yang WL, Wang P.
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| Biol Chem 393(6):429-39. doi: 10.1515/hsz-2012-0103. Review.
2012
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16 | ADM
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| Adrenomedullin is up-regulated in patients with pancreatic cancer and causes insulin resistance in β cells and mice.
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| Aggarwal G, Ramachandran V, Javeed N, Arumugam T, Dutta S, Klee GG, Klee EW, Smyrk TC, Bamlet W, Han JJ, Rumie Vittar NB, de Andrade M, Mukhopadhyay D, Petersen GM, Fernandez-Zapico ME, Logsdon CD, Chari ST.
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| Gastroenterology 143(6):1510-1517.e1. doi: 10.1053/j.gastro.2012.08.044. Epub 2012 Sep 6.
2012
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17 | ADM
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| Adrenomedullin facilitates calcium channel currents in osteoblasts.
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| Tazaki M, Endoh T, Kobayashi H, Nobushima H, Shibukawa Y, Tsumura M, Sato M, Ubaidus S, Sueishi K.
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| Bull Tokyo Dent Coll 53(4):203-6.
2012
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18 | ADM
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| Adrenomedullin as a growth and cell fate regulatory factor for adult neural stem cells.
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| Martínez-Herrero S, Larráyoz IM, Ochoa-Callejero L, García-Sanmartín J, Martínez A.
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| Stem Cells Int 2012:804717. doi: 10.1155/2012/804717. Epub 2012 Sep 24.
2012
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19 | ADM
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| Plasma adrenomedullin and subclinical cardiorenal syndrome in patients with type 2 diabetes mellitus.
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| Pecková M, Charvat J, Schuck O, Zamrazil V, Bilek R, Hill M, Svab P, Horackova M.
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| J Int Med Res 40(4):1552-9.
2012
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20 | ADM
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| Role of adrenomedullin in the growth and differentiation of stem and progenitor cells.
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| Larrayoz IM, Ochoa-Callejero L, García-Sanmartín J, Vicario-Abejón C, Martínez A.
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| Int Rev Cell Mol Biol 297:175-234. doi: 10.1016/B978-0-12-394308-8.00005-4. Review.
2012
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21 | ADM, HIF1A, P4HTM
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| Adrenomedullin promotes human endothelial cell proliferation via HIF-1α.
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| Chen L, Qiu JH, Zhang LL, Luo XD.
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| Mol Cell Biochem 365(1-2):263-73. doi: 10.1007/s11010-012-1267-1. Epub 2012 Mar 11. 2012
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22 | ADM
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| Adrenomedullin: a possible regulator of germinal vesicle breakdown.
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| Hiradate Y, Ohtake J, Hoshino Y, Tanemura K, Sato E.
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| Biochem Biophys Res Commun 415(4):691-5. doi: 10.1016/j.bbrc.2011.10.139. Epub 2011 Nov 4.
2011
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23 | ADM
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| Changes in adrenomedullin in patients with proliferative diabetic retinopathy.
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| Lu Y, Xu Y, Tang C.
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| Curr Eye Res 36(11):1047-52. doi: 10.3109/02713683.2011.594200. Epub 2011 Sep 23.
2011
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24 | ADM
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| Signal transduction pathways mediating the effect of adrenomedullin on osteoblast survival.
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| Lausson S, Cressent M.
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| J Cell Biochem 112(12):3807-15. doi: 10.1002/jcb.23311.
2011
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25 | ADM
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| Adrenomedullin augments the angiogenic potential of late outgrowth endothelial progenitor cells.
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| Hermansen SE, Lund T, Kalstad T, Ytrehus K, Myrmel T.
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| Am J Physiol Cell Physiol 300(4):C783-91. doi: 10.1152/ajpcell.00044.2010. Epub 2011 Jan 5.
2011
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26 | ADM, GDF15, HIF1A, KDM3A
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| Regulation of the histone demethylase JMJD1A by hypoxia-inducible factor 1 alpha enhances hypoxic gene expression and tumor growth.
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| Krieg AJ, Rankin EB, Chan D, Razorenova O, Fernandez S, Giaccia AJ.
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| Mol Cell Biol 30(1):344-53. Epub .
2010
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27 | ADM
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| Adrenomedullin as a therapeutic target in angiogenesis.
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| Deville JL, Salas S, Figarella-Branger D, Ouafik L, Daniel L.
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| Expert Opin Ther Targets 14(10):1059-72. doi: 10.1517/14728222.2010.522328. Review.
2010
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28 | ADM
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| Expression of adrenomedullin in human oviduct, its regulation by the hormonal cycle and contact with spermatozoa, and its effect on ciliary beat frequency of the oviductal epithelium.
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| Li HW, Liao SB, Chiu PC, Tam WW, Ho JC, Ng EH, Ho PC, Yeung WS, Tang F, O WS.
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| J Clin Endocrinol Metab 95(9):E18-25. doi: 10.1210/jc.2010-0273. Epub 2010 Jun 9.
2010
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29 | ADM
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| Adrenomedullin regulates sperm motility and oviductal ciliary beat via cyclic adenosine 5'-monophosphate/protein kinase A and nitric oxide.
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| Chiu PC, Liao S, Lam KK, Tang F, Ho JC, Ho PC, O WS, Yao YQ, Yeung WS.
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| Endocrinology 151(7):3336-47. doi: 10.1210/en.2010-0077. Epub 2010 May 5.
2010
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30 | ADM, KLF15
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| The Krüppel-like factor KLF15 inhibits transcription of the adrenomedullin gene in adipocytes.
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| Nagare T, Sakaue H, Takashima M, Takahashi K, Gomi H, Matsuki Y, Watanabe E, Hiramatsu R, Ogawa W, Kasuga M.
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| Biochem Biophys Res Commun 379(1):98-103. Epub 2008 Dec 16.
2009
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31 | ADM
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| Adrenomedullin stabilizes the lymphatic endothelial barrier in vitro and in vivo.
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| Dunworth WP, Fritz-Six KL, Caron KM.
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| Peptides 29(12):2243-9. Epub 2008 Sep 24.
2008
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32 | ADM, CALCA
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| Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway.
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| Uzan B, Villemin A, Garel JM, Cressent M.
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| J Cell Physiol 215(1):122-8.
2008
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33 | ADM, CFH
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| Purification and characterization of human adrenomedullin binding protein-1.
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| Qiang X, Wu R, Ji Y, Zhou M, Wang P.
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| Mol Med 14(7-8):443-50.PMID: 18496585 2008
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34 | ADM, RAMP2
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| The GPCR modulator protein RAMP2 is essential for angiogenesis and vascular integrity.
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| Ichikawa-Shindo Y, Sakurai T, Kamiyoshi A, Kawate H, Iinuma N, Yoshizawa T, Koyama T, Fukuchi J, Iimuro S, Moriyama N, Kawakami H, Murata T, Kangawa K, Nagai R, Shindo T.
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| J Clin Invest 118(1):29-39.
2008
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35 | ADM
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| Adrenomedullin and endothelial barrier function.
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| Temmesfeld-Wollbrück B, Hocke AC, Suttorp N, Hippenstiel S.
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| Thromb Haemost 98(5):944-51. Review.
2007
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36 | ADM, CALCRL, RAMP2
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| Human calcitonin receptor-like receptor for adrenomedullin: genomic structure, eight single-nucleotide polymorphisms, and haplotype analysis.
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| Nakazawa I, Nakajima T, Harada H, Ishigami T, Umemura S, Emi M.
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| J Hum Genet 46(3):132-6. 2001
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37 | ADM
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| The Adrenomedullin gene is a target for negative regulation by the Myc transcription complex.
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| Wang X, et al.
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| Mol Endocrinol 13(2):254-67. 1999
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38 | ADM
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| Genomic structure of human adrenomedullin gene.
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| Ishimitsu T, et al.
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| Biochem Biophys Res Commun 203 : 631-639. 1994
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39 | ADM
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| Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. ERRATA : vol.202 : p.643 (1994)
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| Kitamura K, et al.
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| Biochem Biophys Res Commun 194 : 720-725. 1993
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