Citations for
1ADGRV1, DNAH5
A novel role for ciliary function in atopy: ADGRV1 and DNAH5 interactions.
Sugier PE, Brossard M, Sarnowski C, Vaysse A, Morin A, Pain L, Margaritte-Jeannin P, Dizier MH, Cookson WOCM, Lathrop M, Moffatt MF, Laprise C, Demenais F, Bouzigon E.
J Allergy Clin Immunol 141(5):1659-1667.e11. doi: 10.1016/j.jaci.2017.06.050. Epub 2017 Sep 18. 2018
2ADGRV1, PDZD7, USH1C, USH2A, WHRN
The roles of USH1 proteins and PDZ domain-containing USH proteins in USH2 complex integrity in cochlear hair cells.
Zou J, Chen Q, Almishaal A, Mathur PD, Zheng T, Tian C, Zheng QY, Yang J.
Hum Mol Genet 26(3):624-636. doi: 10.1093/hmg/ddw421. 2017
3ADGRV1, USH2C
USH2 caused by GPR98 mutation diagnosed by massively parallel sequencing in advance of the occurrence of visual symptoms.
Moteki H, Yoshimura H, Azaiez H, Booth KT, Shearer AE, Sloan CM, Kolbe DL, Murata T, Smith RJ, Usami S.
Ann Otol Rhinol Laryngol 124 Suppl 1:123S-8S. doi: 10.1177/0003489415574070. Epub 2015 Mar 5. 2015
4ADGRV1, CLRN1
Domain analyses of Usher syndrome causing Clarin-1 and GPR98 protein models.
Khan SH, Javed MR, Qasim M, Shahzadi S, Jalil A, Rehman SU.
Bioinformation 10(8):491-5. doi: 10.6026/97320630010491. eCollection 2014. 2014
5ADGRV1, PDZD7
Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein.
Hu QX, Dong JH, Du HB, Zhang DL, Ren HZ, Ma ML, Cai Y, Zhao TC, Yin XL, Yu X, Xue T, Xu ZG, Sun JP.
J Biol Chem 289(35):24215-25. doi: 10.1074/jbc.M114.549816. Epub 2014 Jun 24. 2014
6ADGRV1, MAG
Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.
Shin D, Lin ST, Fu YH, Ptácek LJ.
Proc Natl Acad Sci U S A 110(47):19101-6. doi: 10.1073/pnas.1318501110. Epub 2013 Nov 4. 2013
7ADGRV1, USH2C, WHRN
The contribution of GPR98 and DFNB31 genes to a Spanish Usher syndrome type 2 cohort.
García-García G, Besnard T, Baux D, Vaché C, Aller E, Malcolm S, Claustres M, Millan JM, Roux AF.
Mol Vis 19:367-73. Epub 2013 Feb 13. 2013
8ADGRV1
The very large G protein coupled receptor (Vlgr1) in hair cells.
Sun JP, Li R, Ren HZ, Xu AT, Yu X, Xu ZG.
J Mol Neurosci 50(1):204-14. doi: 10.1007/s12031-012-9911-5. Epub 2012 Nov 20. Review. 2013
9ADGRV1, SNAP25
Regulated vesicular trafficking of specific PCDH15 and VLGR1 variants in auditory hair cells.
Zallocchi M, Delimont D, Meehan DT, Cosgrove D.
J Neurosci 32(40):13841-59. doi: 10.1523/JNEUROSCI.1242-12.2012. 2012
10ADGRV1
GPR98/Gpr98 gene is involved in the regulation of human and mouse bone mineral density.
Urano T, Shiraki M, Yagi H, Ito M, Sasaki N, Sato M, Ouchi Y, Inoue S.
J Clin Endocrinol Metab 97(4):E565-74. doi: 10.1210/jc.2011-2393. Epub 2012 Mar 14. 2012
11ADGRV1, CDH23, CLRN1, PCDH15
Role for a novel Usher protein complex in hair cell synaptic maturation.
Zallocchi M, Meehan DT, Delimont D, Rutledge J, Gratton MA, Flannery J, Cosgrove D.
PLoS One 7(2):e30573. doi: 10.1371/journal.pone.0030573. Epub 2012 Feb 17. 2012
12ADGRV1, CDH23, CLRN1, MYO7A, PCDH15, USH1B, USH1C, USH1D, USH1F, USH1G, USH2A, USH2C, USH2D, USH3A, WHRN
Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.
Zallocchi M, Sisson JH, Cosgrove D.
Biochemistry 49(6):1236-47.PMID: 20058854 2010
13ADGRV1, USH2A, USH2C, USH2D, WHRN
An USH2A founder mutation is the major cause of Usher syndrome type 2 in Canadians of French origin and confirms common roots of Quebecois and Acadians.
Ebermann I, Koenekoop RK, Lopez I, Bou-Khzam L, Pigeon R, Bolz HJ.
Eur J Hum Genet 17(1):80-4. Epub 2008 Jul 30. 2009
14ADGRV1, USH2C
A large deletion in GPR98 causes type IIC Usher syndrome in male and female members of an Iranian family.
Hilgert N, Kahrizi K, Dieltjens N, Bazazzadegan N, Najmabadi H, Smith RJ, Van Camp G.
J Med Genet 46(4):272-6. 2009
15ADGRV1, USH2C
GPR98 mutations cause Usher syndrome type 2 in males.
Ebermann I, Wiesen MH, Zrenner E, Lopez I, Pigeon R, Kohl S, Löwenheim H, Koenekoop RK, Bolz HJ.
J Med Genet 46(4):277-80. 2009
16ADGRV1, PDE6B
Identification of two new mutations in the GPR98 and the PDE6B genes segregating in a Tunisian family.
Hmani-Aifa M, Benzina Z, Zulfiqar F, Dhouib H, Shahzadi A, Ghorbel A, Rebaï A, Söderkvist P, Riazuddin S, Kimberling WJ, Ayadi H.
Eur J Hum Genet 17(4):474-82. Epub 2008 Oct 15. 2009
17ADGRV1, CETN3, DEL5Q14, LYSMD3, POLR3G
A novel microdeletion syndrome involving 5q14.3-q15: clinical and molecular cytogenetic characterization of three patients.
Engels H, Wohlleber E, Zink A, Hoyer J, Ludwig KU, Brockschmidt FF, Wieczorek D, Moog U, Hellmann-Mersch B, Weber RG, Willatt L, Kreiss-Nachtsheim M, Firth HV, Rauch A.
Eur J Hum Genet 17(12):1592-9. Epub 2009 May 27. 2009
18ADGRV1, MYO7A, USH1G, VEZT, WHRN
A novel Usher protein network at the periciliary reloading point between molecular transport machineries in vertebrate photoreceptor cells.
Maerker T, van Wijk E, Overlack N, Kersten FF, McGee J, Goldmann T, Sehn E, Roepman R, Walsh EJ, Kremer H, Wolfrum U.
Hum Mol Genet 17(1):71-86. Epub 2007 Sep 28. 2008
19ADGRV1, MYO7A, PCDH15, USH1B, USH1F, USH2A, USH2C
Usher syndromes due to MYO7A, PCDH15, USH2A or GPR98 mutations share retinal disease mechanism.
Jacobson SG, Cideciyan AV, Aleman TS, Sumaroka A, Roman AJ, Gardner LM, Prosser HM, Mishra M, Bech-Hansen NT, Herrera W, Schwartz SB, Liu XZ, Kimberling WJ, Steel KP, Williams DS.
Hum Mol Genet 17(15):2405-15. Epub 2008 May 7. 2008
20ADGRV1, USH2A, VEZT, WHRN
Molecular characterization of the ankle-link complex in cochlear hair cells and its role in the hair bundle functioning.
Michalski N, Michel V, Bahloul A, Lefèvre G, Barral J, Yagi H, Chardenoux S, Weil D, Martin P, Hardelin JP, Sato M, Petit C.
J Neurosci 27(24):6478-88. 2007
21ADGRV1, USH2A, WHRN
The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1.
van Wijk E, van der Zwaag B, Peters T, Zimmermann U, Te Brinke H, Kersten FF, Marker T, Aller E, Hoefsloot LH, Cremers CW, Cremers FP, Wolfrum U, Knipper M, Roepman R, Kremer H.
Hum Mol Genet 15(5):751-65. Epub 2006 Jan 24. 2006
22ADGRV1, CDH23, CLRN1, MYO7A, PCDH15, USH1B, USH1C, USH1D, USH1F, USH2B, USH2C
First evidence for a molecular link between Usher 1 and Usher 2 syndromes.
Stein R.
Clin Genet 69(6):483-485. No abstract available. 2006
23ADGRV1, USH1C
The Mass1frings mutation underlies early onset hearing impairment in BUB/BnJ mice, a model for the auditory pathology of Usher syndrome IIC.
Johnson KR, Zheng QY, Weston MD, Ptacek LJ, Noben-Trauth K.
Genomics 85(5):582-90. 2005
24ADGRV1, SLC4A7, USH1C, USH2A
Scaffold protein harmonin (USH1C) provides molecular links between Usher syndrome type 1 and type 2.
Reiners J, van Wijk E, Marker T, Zimmermann U, Jurgens K, te Brinke H, Overlack N, Roepman R, Knipper M, Kremer H, Wolfrum U.
Hum Mol Genet 14(24):3933-43. Epub 2005 Nov 21. 2005
25ADGRV1, USH2A, USH2C
Disease expression in Usher syndrome caused by VLGR1 gene mutation (USH2C) and comparison with USH2A phenotype.
Schwartz SB, Aleman TS, Cideciyan AV, Windsor EA, Sumaroka A, Roman AJ, Rane T, Smilko EE, Bennett J, Stone EM, Kimberling WJ, Liu XZ, Jacobson SG.
Invest Ophthalmol Vis Sci 46(2):734-43. 2005
26ADGRV1, USH2C
Mutations in the VLGR1 Gene Implicate G-Protein Signaling in the Pathogenesis of Usher Syndrome Type II.
Weston MD, Luijendijk MW, Humphrey KD, Moller C, Kimberling WJ.
Am J Hum Genet 74(2):357-66. Epub 2004 Jan 20. 2004
27ADGRA3, ADGRB1, ADGRB2, ADGRB3, ADGRG1, ADGRG2, ADGRG6, ADGRL1, ADGRL2, ADGRL3, ADGRL4, ADGRV1, CD97, EMR3, GPR110, GPR111, GPR114, GPR115, GPR116, GPR124, GPR133, GPR144, GPR97
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.
Bjarnadottir TK, Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB.
Genomics 84(1):23-33. 2004
28ADGRV1
Very large G protein-coupled receptor-1, the largest known cell surface protein, is highly expressed in the developing central nervous system.
McMillan DR, Kayes-Wandover KM, Richardson JA, White PC.
J Biol Chem 277(1):785-92. 2002
29ADGRV1, FEB4
A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures.
Nakayama J, Fu YH, Clark AM, Nakahara S, Hamano K, Iwasaki N, Matsui A, Arinami T, Ptacek LJ.
Ann Neurol 52(5):654-7. 2002
30ADGRV1, LGI1, LGI2, LGI3, LGI4, TSPEAR
A common protein interaction domain links two recently identified epilepsy genes.
Scheel H, Tomiuk S, Hofmann K.
Hum Mol Genet 11(15):1757-62. 2002
31ADGRV1, FEB4
A nonsense mutation of the MASS1 gene in a family with febrile and afebrile seizures.
Nakayama J, Fu YH, Clark AM, Nakahara S, Hamano K, Iwasaki N, Matsui A, Arinami T, Ptácek LJ.
Ann Neurol 52(5):654-7. 2002
32ADGRV1
A novel gene causing a mendelian audiogenic mouse epilepsy.
Skradski SL, Clark AM, Jiang H, White HS, Fu YH, Ptacek LJ.
Neuron 31(4):537-44. 2001
33ADGRV1
Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain.
Nikkila H, McMillan DR, Nunez BS, Pascoe L, Curnow KM, White PC.
Mol Endocrinol 14(9):1351-64. 2000
34ADGRV1
Structural requirements for alpha-latrotoxin binding and alpha-latrotoxin-stimulated secretion. A study with calcium-independent receptor of alpha-latrotoxin (cirl) deletion mutants.
Krasnoperov V, et al.
J Biol Chem 274 : 3590-3596. 1999
35ADGRV1, LPHN2
The latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution.
Matsushita H, et al.
FEBS Lett 443(3):348-52. 1999
36ADGRV1
Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor.
Lang J, et al.
EMBO J 17 : 648-657. 1998
37ADGRV1, NRXN1
Alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis.
Sugita S, et al.
J Biol Chem 273 : 32715-32724. 1998
38AATK, ACIN1, ACOT11, ACSBG1, ADAMTS4, ADGRV1, AKAP11, ANKLE2, ARHGAP26, ARHGEF2, ASTN2, ATP2C2, ATP9A, BICD2, BZRAP1, C12orf51, CAND2, CEP135, CLASP1, CLASP2, CLUAP1, CLUH, CNOT3, COBL, CPNE3, CRTC1, CRY2, CSTF2T, CUL3, CUL4B, DAAM1, DAGLA, DEPDC5, DNAJC13, DOCK10, DZIP3, FBXW11, FKBP15, G3BP2, HEPH, HIP1R, HIPK1, ICOSLG, KIAA0649, KIAA0652, KIF13B, KIF1C, KIF21A, L3MBTL1, LDB3, MAGI2, MAP4K4, MFAP3L, MGEA5, MRC2, MTMR4, N4BP1, NPHP4, OBSL1, PAN2, PHACTR2, PHF2, PHLDB1, PLXND1, PPFIA3, PTCD1, RAB11FIP3, RBM19, RICH2, RNF40, RNF8, ROCK2, RRP12, SAPS2, SETX, SIN3B, SLC24A1, SMCHD1, SNAP91, SOCS5, SS18L1, SWAP70, TBC1D9B, TELO2, TNRC15, TSC22D2, UBE4B, UHRF1BP1L, ULK2, ZBED4, ZC3H11A, ZNF623
Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N,Ohara O.
DNA Res 5(3):169-76. 1998
39ADGRV1
Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors.
Lelianova VG, et al.
J Biol Chem 272 : 21504-21508. 1997