1 | ADGRG6
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| The COPD GWAS gene ADGRG6 instructs function and injury response in human iPSC-derived type II alveolar epithelial cells
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| Werder RB, Berthiaume KA, Merritt C, Gallagher M, Villacorta-Martin C, Wang F, Bawa P, Malik V, Lyons SM, Basil MC, Morrisey EE, Kotton DN, Zhou X, Cho MH, Wilson AA.
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| Am J Hum Genet. Oct 5;110(10):1735-1749. doi: 10.1016/j.ajhg.2023.08.017. Epub 2023 Sep 20 2023
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2 | ADGRG6
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| Structure, ligands, and roles of GPR126/ADGRG6 in the development and diseases.
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| Li Q, Huo A, Li M, Wang J, Yin Q, Chen L, Chu X, Qin Y, Qi Y, Li Y, Cui H, Cong Q.
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| Genes Dis Mar 27;11(1):294-305. doi: 10.1016/j.gendis.2023.02.016. 2023
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3 | ADGRG6
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| Adhesion GPCR Gpr126 (Adgrg6) Expression Profiling in Zebrafish, Mouse, and Human Kidney.
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| Cazorla-Vázquez S, Kösters P, Bertz S, Pfister F, Daniel C, Dedden M, Zundler S, Jobst-Schwan T, Amann K, Engel FB.
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| Cells Aug 2;12(15):1988. doi: 10.3390/cells12151988. 2023
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4 | ADGRG6, AMCN4
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| A novel biallelic variant c.2219T > A p.(Leu740*) in ADGRG6 as a cause of lethal congenital contracture syndrome 9. 2023 PMID:
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| Shravya MS, Mathew M, Vasudeva A, Girisha KM, Nayak SS.
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| Clin Genet. Jan;103(1):127-129. doi: 10.1111/cge.14237. Epub 2022 Oct 9. 2022
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5 | ADGRG6
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| Adhesion G protein-coupled receptor Gpr126/Adgrg6 is essential for placental development. 2021. PMID:
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| Torregrosa-Carrión R, Pińeiro-Sabarís R, Siguero-Álvarez M, Grego-Bessa J, Luna-Zurita L, Fernandes VS, MacGrogan D, Stainier DYR, de la Pompa JL.
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| Sci Adv. Nov 12;7(46):eabj5445. doi: 10.1126/sciadv.abj5445. Epub 2021 Nov 12 2021
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6 | ADGRG6
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| Gpr126/Adgrg6 contributes to the terminal Schwann cell response at the neuromuscular junction following peripheral nerve injury. 2020 . PMID:
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| Jablonka-Shariff A, Lu CY, Campbell K, Monk KR, Snyder-Warwick AK.
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| Glia. Jun;68(6):1182-1200. doi: 10.1002/glia.23769. Epub 2019 Dec 24 2020
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7 | ADGRG6
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| Structural basis for adhesion G protein-coupled receptor Gpr126 function.
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| Leon K, Cunningham RL, Riback JA, Feldman E, Li J, Sosnick TR, Zhao M, Monk KR, Araç D.
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| Nat Commun. Jan 10;11(1):194. doi: 10.1038/s41467-019-14040-1 2020
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8 | ADGRG6
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| Gpr126 (Adgrg6) is expressed in cell types known to be exposed to mechanical stimuli.
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| Musa G, Cazorla-Vázquez S, van Amerongen MJ, Stemmler MP, Eckstein M, Hartmann A, Braun T, Brabletz T, Engel FB.
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| Ann N Y Acad Sci. Nov;1456(1):96-108. doi: 10.1111/nyas.14135. Epub 2019 Jun 19. 2019
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9 | ADGRG6
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| Gpr126/Adgrg6 Has Schwann Cell Autonomous and Nonautonomous Functions in Peripheral Nerve Injury and Repair
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| Mogha A, Harty BL, Carlin D, Joseph J, Sanchez NE, Suter U, Piao X, Cavalli V, Monk KR.
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| J Neurosci. Dec 7;36(49):12351-12367. doi: 10.1523/JNEUROSCI.3854-15.2016. 2016
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10 | ADGRG6, AMCN4
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| Mutations of GPR126 Are Responsible for Severe Arthrogryposis Multiplex Congenita.
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| Ravenscroft G, Nolent F, Rajagopalan S, Meireles AM, Paavola KJ, Gaillard D, Alanio E, Buckland M, Arbuckle S, Krivanek M, Maluenda J, Pannell S, Gooding R, Ong RW, Allcock RJ, Carvalho ED, Carvalho MD, Kok F, Talbot WS, Melki J, Laing NG.
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| Am J Hum Genet 96(6):955-61. doi: 10.1016/j.ajhg.2015.04.014. Epub 2015 May 21. 2015
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11 | ADGRG6
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| GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling.
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| Cui H, Wang Y, Huang H, Yu W, Bai M, Zhang L, Bryan BA, Wang Y, Luo J, Li D, Ma Y, Liu M
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| J Biol Chem. Dec 12;289(50):34871-85. doi: 10.1074/jbc.M114.571000. Epub 2014 Sep 12. 2014
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12 | ADGRG6
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| Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activation.
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| Mogha A, Benesh AE, Patra C, Engel FB, Schöneberg T, Liebscher I, Monk KR.
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| J Neurosci 33(46):17976-85. doi: 10.1523/JNEUROSCI.1809-13.2013. 2013
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13 | ADGRG6
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| Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent.
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| Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB.
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| Proc Natl Acad Sci U S A 110(42):16898-903. doi: 10.1073/pnas.1304837110. Epub 2013 Sep 30. Erratum in: Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1222 2013
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14 | ADGRG6
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| Gpr126 is essential for peripheral nerve development and myelination in mammals.
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| Monk KR, Oshima K, Jörs S, Heller S, Talbot WS.
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| Development 138(13):2673-80. Epub 2011 May 25. 2011
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15 | ADGRG6
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| The orphan adhesion-GPCR GPR126 is required for embryonic development in the mouse.
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| Waller-Evans H, Prömel S, Langenhan T, Dixon J, Zahn D, Colledge WH, Doran J, Carlton MB, Davies B, Aparicio SA, Grosse J, Russ AP.
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| PLoS One 5(11):e14047. 2010
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16 | ADGRG6
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| A G protein-coupled receptor is essential for Schwann cells to initiate myelination.
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| Monk KR, Naylor SG, Glenn TD, Mercurio S, Perlin JR, Dominguez C, Moens CB, Talbot WS.
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| Science 325(5946):1402-5.PMID: 19745155 2009
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17 | ADGRG6, STQTL1
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| Many sequence variants affecting diversity of adult human height.
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| Gudbjartsson DF, Walters GB, Thorleifsson G, Stefansson H, Halldorsson BV, Zusmanovich P, Sulem P, Thorlacius S, Gylfason A, Steinberg S, Helgadottir A, Ingason A, Steinthorsdottir V, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Pedersen O, Aben KK, Witjes JA, Swinkels DW, den Heijer M, Franke B, Verbeek AL, Becker DM, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Gulcher J, Kiemeney LA, Kong A, Thorsteinsdottir U, Stefansson K.
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| Nat Genet 40(5):609-15. Epub 2008 Apr 6. 2008
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18 | ADGRA3, ADGRB1, ADGRB2, ADGRG1, ADGRG2, ADGRG6, ADGRL1, ADGRL2, ADGRL3, CD97, CELSR2, CELSR3, EMR1, EMR2, EMR3, EMR4P, GPR110, GPR112, GPR113, GPR114, GPR116, GPR123, GPR124, GPR133, GPR97
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| Identification of novel splice variants of Adhesion G protein-coupled receptors.
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| Bjarnadottir TK, Geirardsdottir K, Ingemansson M, Mirza MA, Fredriksson R, Schioth HB.
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| Gene 387(1-2):38-48. Epub 2006 Aug 30. 2007
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19 | ADGRG6
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| VIGR--a novel inducible adhesion family G-protein coupled receptor in endothelial cells.
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| Stehlik C, Kroismayr R, Dorfleutner A, Binder BR, Lipp J.
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| FEBS Lett 569(1-3):149-55. 2004
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20 | ADGRA3, ADGRB1, ADGRB2, ADGRB3, ADGRG1, ADGRG2, ADGRG6, ADGRL1, ADGRL2, ADGRL3, ADGRL4, ADGRV1, CD97, EMR3, GPR110, GPR111, GPR114, GPR115, GPR116, GPR124, GPR133, GPR144, GPR97
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| The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.
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| Bjarnadottir TK, Fredriksson R, Hoglund PJ, Gloriam DE, Lagerstrom MC, Schioth HB.
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| Genomics 84(1):23-33. 2004
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21 | ADGRA3, ADGRG6, EMR4P, GPR128
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| There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini.
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| Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB.
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| Biochem Biophys Res Commun 301(3):725-34. 2003
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