| 1 | ADARB1, NEDHYMS
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| Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures.
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| Tan TY, Sedmík J, Fitzgerald MP, Halevy RS, Keegan LP, Helbig I, Basel-Salmon L, Cohen L, Straussberg R, Chung WK, Helal M, Maroofian R, Houlden H, Juusola J, Sadedin S, Pais L, Howell KB, White SM, Christodoulou J, O'Connell MA.
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| Am J Hum Genet. Apr 2;106(4):467-483. doi: 10.1016/j.ajhg.2020.02.015. Epub 2020 Mar 26 2020
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| 2 | ADARB1, NEDHYMS
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| Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy.
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| Maroofian R, Sedmík J, Mazaheri N, Scala M, Zaki MS, Keegan LP, Azizimalamiri R, Issa M, Shariati G, Sedaghat A, Beetz C, Bauer P, Galehdari H, O'Connell MA, Houlden H.
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| J Med Genet. Jul 27:jmedgenet-2020-107048. doi: 10.1136/jmedgenet-2020-107048. Online ahead of print 2020
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| 3 | ADARB1, ELAVL1, PARN
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| ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins.
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| Anantharaman A, Tripathi V, Khan A, Yoon JH, Singh DK, Gholamalamdari O, Guang S, Ohlson J, Wahlstedt H, Öhman M, Jantsch MF, Conrad NK, Ma J, Gorospe M, Prasanth SG, Prasanth KV.
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| Nucleic Acids Res 45(7):4189-4201. doi: 10.1093/nar/gkw1304.
2017
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| 4 | ADAR, ADARB1
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| RNA-editing enzymes ADAR1 and ADAR2 coordinately regulate the editing and expression of Ctn RNA.
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| Anantharaman A, Gholamalamdari O, Khan A, Yoon JH, Jantsch MF, Hartner JC, Gorospe M, Prasanth SG, Prasanth KV.
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| FEBS Lett 591(18):2890-2904. doi: 10.1002/1873-3468.12795. Epub 2017 Aug 30.
2017
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| 5 | ADAR, ADARB1
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| Testicular adenosine to inosine RNA editing in the mouse is mediated by ADARB1.
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| Snyder EM, Licht K, Braun RE.
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| Biol Reprod 96(1):244-253. doi: 10.1095/biolreprod.116.145151.
2017
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| 6 | ADARB1, KPNA3
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| Accumulation of nuclear ADAR2 regulates adenosine-to-inosine RNA editing during neuronal development.
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| Behm M, Wahlstedt H, Widmark A, Eriksson M, Öhman M.
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| J Cell Sci 130(4):745-753. doi: 10.1242/jcs.200055. Epub 2017 Jan 12.
2017
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| 7 | ADARB1
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| ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm.
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| Terajima H, Yoshitane H, Ozaki H, Suzuki Y, Shimba S, Kuroda S, Iwasaki W, Fukada Y.
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| Nat Genet 49(1):146-151. doi: 10.1038/ng.3731. Epub 2016 Nov 28.
2017
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| 8 | ADARB1
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| RNA editing enzyme ADAR2 is a mediator of neuropathic pain after peripheral nerve injury.
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| Uchida H, Matsumura S, Okada S, Suzuki T, Minami T, Ito S.
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| FASEB J 31(5):1847-1855. doi: 10.1096/fj.201600950R. Epub 2017 Jan 26.
2017
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| 9 | ADARB1
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| ADAR2 affects mRNA coding sequence edits with only modest effects on gene expression or splicing in vivo.
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| Dillman AA, Cookson MR, Galter D.
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| RNA Biol 13(1):15-24. doi: 10.1080/15476286.2015.1110675.
2016
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| 10 | ADARB1
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| Reduced levels of protein recoding by A-to-I RNA editing in Alzheimer's disease.
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| Khermesh K, D'Erchia AM, Barak M, Annese A, Wachtel C, Levanon EY, Picardi E, Eisenberg E.
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| RNA 22(2):290-302. doi: 10.1261/rna.054627.115. Epub 2015 Dec 11. 2016
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| 11 | ADARB1, ILF3
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| Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA.
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| Jayachandran U, Grey H, Cook AG.
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| Nucleic Acids Res 44(4):1924-36. doi: 10.1093/nar/gkv1508. Epub 2015 Dec 27.
2016
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| 12 | ADARB1
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| Aberrant alternative splicing pattern of ADAR2 downregulates adenosine-to-inosine editing in glioma.
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| Li Z, Tian Y, Tian N, Zhao X, Du C, Han L, Zhang H.
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| Oncol Rep 33(6):2845-52. doi: 10.3892/or.2015.3907. Epub 2015 Apr 8.
2015
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| 13 | ADARB1
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| Down-regulation of the RNA editing enzyme ADAR2 contributes to RGC death in a mouse model of glaucoma.
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| Wang AL, Carroll RC, Nawy S.
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| PLoS One 9(3):e91288. doi: 10.1371/journal.pone.0091288. eCollection 2014.
2014
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| 14 | ADARB1
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| Unique nuclear vacuoles in the motor neurons of conditional ADAR2-knockout mice.
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| Sasaki S, Takenari Yamashita, Hideyama T, Kwak S.
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| Brain Res 1550:36-46. doi: 10.1016/j.brainres.2014.01.006. Epub 2014 Jan 15.
2014
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| 15 | ADARB1
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| ADAR2-editing activity inhibits glioblastoma growth through the modulation of the CDC14B/Skp2/p21/p27 axis.
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| Galeano F, Rossetti C, Tomaselli S, Cifaldi L, Lezzerini M, Pezzullo M, Boldrini R, Massimi L, Di Rocco CM, Locatelli F, Gallo A.
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| Oncogene 32(8):998-1009. doi: 10.1038/onc.2012.125. Epub 2012 Apr 23.
2013
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| 16 | ADARB1
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| Profound downregulation of the RNA editing enzyme ADAR2 in ALS spinal motor neurons.
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| Hideyama T, Yamashita T, Aizawa H, Tsuji S, Kakita A, Takahashi H, Kwak S.
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| Neurobiol Dis 45(3):1121-8. Epub 2011 Dec 28.
2012
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| 17 | ADARB1, MAPK8
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| c-Jun amino-terminal kinase-1 mediates glucose-responsive upregulation of the RNA editing enzyme ADAR2 in pancreatic beta-cells.
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| Yang L, Huang P, Li F, Zhao L, Zhang Y, Li S, Gan Z, Lin A, Li W, Liu Y.
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| PLoS One 7(11):e48611. doi: 10.1371/journal.pone.0048611. Epub 2012 Nov 6.
2012
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| 18 | ADAR, ADARB1
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| Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: loss of ADAR1 in insects.
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| Keegan LP, McGurk L, Palavicini JP, Brindle J, Paro S, Li X, Rosenthal JJ, O'Connell MA.
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| Nucleic Acids Res 39(16):7249-62. Epub 2011 May 27.
2011
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| 19 | ADARB1, PIN1, WWP2
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| Pin1 and WWP2 regulate GluR2 Q/R site RNA editing by ADAR2 with opposing effects.
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| Marcucci R, Brindle J, Paro S, Casadio A, Hempel S, Morrice N, Bisso A, Keegan LP, Del Sal G, O'Connell MA.
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| EMBO J 30(20):4211-22. doi: 10.1038/emboj.2011.303.
2011
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| 20 | ADARB1
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| ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor.
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| Doria M, Tomaselli S, Neri F, Ciafrč SA, Farace MG, Michienzi A, Gallo A.
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| J Gen Virol 92(Pt 5):1228-32. Epub 2011 Feb 2.
2011
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| 21 | ADARB1
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| TDP-43 pathology in sporadic ALS occurs in motor neurons lacking the RNA editing enzyme ADAR2.
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| Aizawa H, Sawada J, Hideyama T, Yamashita T, Katayama T, Hasebe N, Kimura T, Yahara O, Kwak S.
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| Acta Neuropathol 120(1):75-84. Epub 2010 Apr 7.
2010
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| 22 | ADAR, ADARB1
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| ADAR1 and ADAR2 expression and editing activity during forebrain development.
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| Jacobs MM, Fogg RL, Emeson RB, Stanwood GD.
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| Dev Neurosci 31(3):223-37. Epub 2009 Mar 27.
2009
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| 23 | ADARB1
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| Novel exon of mammalian ADAR2 extends open reading frame.
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| Maas S, Gommans WM.
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| PLoS One 4(1):e4225. Epub 2009 Jan 19.
2009
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| 24 | ADAR, ADARB1
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| Down-regulation of RNA editing in pediatric astrocytomas: ADAR2 editing activity inhibits cell migration and proliferation.
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| Cenci C, Barzotti R, Galeano F, Corbelli S, Rota R, Massimi L, Di Rocco C, O'Connell MA, Gallo A.
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| J Biol Chem 283(11):7251-60. Epub 2008 Jan 4.
2008
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| 25 | ADARB1
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| Changes in serum adenosine deaminase activity during normal pregnancy.
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| Lee SJ, Hwang HS, Kim BN, Kim MA, Lee JW, Park YW, Kim YH.
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| J Korean Med Sci 22(4):718-21. 2007
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| 26 | ADARB1
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| Dimerization of ADAR2 is mediated by the double-stranded RNA binding domain.
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| Poulsen H, Jorgensen R, Heding A, Nielsen FC, Bonven B, Egebjerg J.
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| RNA 12(7):1350-60. Epub 2006 May 8. 2006
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| 27 | ADARB1
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| ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs.
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| Vitali P, Basyuk E, Le Meur E, Bertrand E, Muscatelli F, Cavaillé J, Huttenhofer A.
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| J Cell Biol 169(5):745-53.
2005
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| 28 | ADAR, ADARB2, ADARB1
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| RNA editing activity is associated with splicing factors in lnRNP particles: The nuclear pre-mRNA processing machinery.
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| Raitskin O, Cho DS, Sperling J, Nishikura K, Sperling R.
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| Proc Natl Acad Sci U S A 98(12):6571-6. 2001
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| 29 | ADARB1, C21orf33, CABIN1, COL18A1, COL6A1, COL6A2, CSTB, ILVBL, ITGB2, KRTAP12-1, PDXK, PFKL, PGA1, PRMT2, S100B, TRAPPC10, TRPM2, UBE2G2
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| Perfect conserved linkage across the entire mouse chromosome 10 region homologous to human chromosome 21.
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| Wiltshire T, Pletcher M, Cole SE, Villanueva M, Birren B, Lehoczky J, Dewar K, Reeves RH.
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| Genome Res 9(12):1214-22 1999
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| 30 | ADARB1, CFAP410, LSS, PFKL, SLC19A1, SUMO3
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| Construction of a 2.5-Mb integrated physical and gene map of distal 21q22.3.
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| Lapenta V, Sossi V, Gosset P, Vayssettes C, Vitali T, Rabatel N, Tassone F, Blouin JL, Scott HS, Antonarakis SE, Creau N, Brahe C.
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| Genomics 49(1):1-13. 1998
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| 31 | ADARB1
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| Cloning of a human RNA editing deaminase (ADARB1) of glutamate receptors that maps to chromosome 21q22.3.
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| Mittaz L, et al.
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| Genomics 41 : 210-217. 1997
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| 32 | ADARB1, HTR2A, HTR2B, HTR2C
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| Regulation of serotonin-2C receptor G-protein coupling by RNA editing.
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| Burns CM, Chu H, Rueter SM, Hutchinson LK, Canton H, Sanders-Bush E, Emeson RB.
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| Nature 387(6630):303-8. 1997
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| 33 | ADARB1, ADARB2
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| Human RNA editing deaminases (hREDs) : characterisation of hRED1 which maps to chromosome 21q22.3, and localisation of hRED2 to chromosome 10p15. (abstr)
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| Mittaz L, et al.
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| Medizinische Genetik 9 : 115. 1997
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