| 1 | ADAMTS5, KLHL10, TEX11
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| An in silico analysis of human sperm genes associated with asthenozoospermia and its implication in male infertility
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| Liu XX, Cai L, Liu FJ.
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| Medicine (Baltimore). Dec;97(49):e13338. doi: 10.1097/MD.0000000000013338. 2018
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| 2 | ADAMTS5, MMP3, SDC4
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| Syndecan-4 in intervertebral disc and cartilage: Saint or synner?
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| Binch AL, Shapiro IM, Risbud MV.
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| Matrix Biol 52-54:355-62. doi: 10.1016/j.matbio.2016.01.005. Epub 2016 Jan 18. Review.
2016
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| 3 | ADAMTS4, ADAMTS5, MATN2
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| Matrilin-2 is proteolytically cleaved by ADAMTS-4 and ADAMTS-5
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| Wang Z, Luo J, Iwamoto S, Chen Q.
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| Molecules. Jun 23;19(6):8472-87. doi: 10.3390/molecules19068472. 2014
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| 4 | ADAMTS5, LRP1
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| LRP-1-mediated endocytosis regulates extracellular activity of ADAMTS-5 in articular cartilage.
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| Yamamoto K, Troeberg L, Scilabra SD, Pelosi M, Murphy CL, Strickland DK, Nagase H.
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| FASEB J 27(2):511-21. doi: 10.1096/fj.12-216671. Epub 2012 Oct 11.
2013
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| 5 | ADAMTS5, RELA
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| Transcriptional induction of ADAMTS5 protein by nuclear factor-κB (NF-κB) family member RelA/p65 in chondrocytes during osteoarthritis development.
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| Kobayashi H, Hirata M, Saito T, Itoh S, Chung UI, Kawaguchi H.
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| J Biol Chem 288(40):28620-9. doi: 10.1074/jbc.M113.452169. Epub 2013 Aug 20.
2013
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| 6 | ADAMTS5, SMAD2, VCAN
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| Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves.
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| Dupuis LE, Osinska H, Weinstein MB, Hinton RB, Kern CB.
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| J Mol Cell Cardiol 60:50-9. doi: 10.1016/j.yjmcc.2013.03.010. Epub 2013 Mar 24.
2013
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| 7 | ADAMTS5
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| Regulation of aggrecanases from the ADAMTS family and aggrecan neoepitope formation during in vitro chondrogenesis of human mesenchymal stem cells.
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| Boeuf S, Graf F, Fischer J, Moradi B, Little CB, Richter W.
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| Eur Cell Mater 23:320-32.
2012
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| 8 | ADAMTS5
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| Murine tendon function is adversely affected by aggrecan accumulation due to the knockout of ADAMTS5.
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| Wang VM, Bell RM, Thakore R, Eyre DR, Galante JO, Li J, Sandy JD, Plaas A.
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| J Orthop Res 30(4):620-6. doi: 10.1002/jor.21558. Epub 2011 Sep 16.
2012
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| 9 | ADAMTS5
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| Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.
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| Dupuis LE, McCulloch DR, McGarity JD, Bahan A, Wessels A, Weber D, Diminich AM, Nelson CM, Apte SS, Kern CB.
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| Dev Biol 357(1):152-64. Epub 2011 Jul 1.
2011
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| 10 | ADAMTS5
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| Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis.
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| Hattori N, Carrino DA, Lauer ME, Vasanji A, Wylie JD, Nelson CM, Apte SS.
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| J Biol Chem 286(39):34298-310. Epub 2011 Aug 2.
2011
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| 11 | ADAMTS4, ADAMTS5
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| Matrilin-4 is processed by ADAMTS-5 in late Golgi vesicles present in growth plate chondrocytes of defined differentiation state.
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| Groma G, Grskovic I, Schael S, Ehlen HW, Wagener R, Fosang A, Aszodi A, Paulsson M, Brachvogel B, Zaucke F.
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| Matrix Biol 30(4):275-80. doi: 10.1016/j.matbio.2011.04.002. Epub 2011 Apr 22.
2011
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| 12 | ADAMTS5, SDC4
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| Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown in osteoarthritis.
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| Echtermeyer F, Bertrand J, Dreier R, Meinecke I, Neugebauer K, Fuerst M, Lee YJ, Song YW, Herzog C, Theilmeier G, Pap T.
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| Nat Med 15(9):1072-6. Epub 2009 Aug 16.
2009
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| 13 | ADAMTS4, ADAMTS5
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| The C-terminal domains of ADAMTS-4 and ADAMTS-5 promote association with N-TIMP-3.
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| Troeberg L, Fushimi K, Scilabra SD, Nakamura H, Dive V, Thøgersen IB, Enghild JJ, Nagase H.
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| Matrix Biol 28(8):463-9. Epub 2009 Jul 28.
2009
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| 14 | ADAMTS4, ADAMTS5
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| Conserved sequence in the aggrecan interglobular domain modulates cleavage by ADAMTS-4 and ADAMTS-5.
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| Miwa HE, Gerken TA, Huynh TD, Duesler LR, Cotter M, Hering TM.
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| Biochim Biophys Acta 1790(3):161-72. Epub 2008 Dec 6.
2009
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| 15 | ADAMTS4, ADAMTS5
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| Functional differences of the catalytic and non-catalytic domains in human ADAMTS-4 and ADAMTS-5 in aggrecanolytic activity.
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| Fushimi K, Troeberg L, Nakamura H, Lim NH, Nagase H.
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| J Biol Chem 283(11):6706-16. Epub 2007 Dec 22. 2008
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| 16 | ADAMTS5
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| A transcriptional enhancer from the coding region of ADAMTS5.
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| Barthel KK, Liu X.
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| PLoS One 3(5):e2184.
2008
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| 17 | ADAMTS4,ADAMTS5
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| Proteolytic activities of human ADAMTS-5: comparative studies with ADAMTS-4.
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| Gendron C, Kashiwagi M, Lim NH, Enghild JJ, Thogersen IB, Hughes C, Caterson B, Nagase H.
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| J Biol Chem 282(25):18294-306. Epub 2007 Apr 12. 2007
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| 18 | ADAMTS16, ADAMTS18, ADAMTS4, ADAMTS5, ADAMTS9
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| Glycosaminoglycan-binding properties and aggrecanase activities of truncated ADAMTSs: comparative analyses with ADAMTS-5, -9, -16 and -18.
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| Zeng W, Corcoran C, Collins-Racie LA, Lavallie ER, Morris EA, Flannery CR.
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| Biochim Biophys Acta 1760(3):517-24. Epub 2006 Feb 17.
2006
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| 19 | ADAMTS5,BCAN
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| Human glioblastomas overexpress ADAMTS-5 that degrades brevican.
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| Nakada M, Miyamori H, Kita D, Takahashi T, Yamashita J, Sato H, Miura R, Yamaguchi Y, Okada Y.
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| Acta Neuropathol (Berl) 110(3):239-46. Epub 2005 Aug 30. 2005
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| 20 | ADAMTS4, ADAMTS5
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| Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes.
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| Tortorella MD, Arner EC, Hills R, Easton A, Korte-Sarfaty J, Fok K, Wittwer AJ, Liu RQ, Malfait AM.
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| J Biol Chem 279(17):17554-61. Epub 2004 Jan 7. 2004
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| 21 | ADAMTS1, ADAMTS2, ADAMTS3, ADAMTS4, ADAMTS5, ADAMTS6, ADAMTS7, ADAMTS8, ADAMTS9, TIMP3
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| Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: transcriptional regulation by TNFalpha.
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| Bevitt DJ, Mohamed J, Catterall JB, Li Z, Arris CE, Hiscott P, Sheridan C, Langton KP, Barker MD, Clarke MP, McKie N.
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| Biochim Biophys Acta 1626(1-3):83-91. 2003
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| 22 | ADAMTS4, ADAMTS5
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| Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage.
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| Malfait AM, Liu RQ, Ijiri K, Komiya S, Tortorella MD.
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| J Biol Chem 277(25):22201-8. Epub 2002 Apr 15. 2002
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| 23 | ADAMTS5
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| Expression and activity of ADAMTS-5 in synovium.
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| Vankemmelbeke MN, Holen I, Wilson AG, Ilic MZ, Handley CJ, Kelner GS, Clark M, Liu C, Maki RA, Burnett D, Buttle DJ.
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| Eur J Biochem 268(5):1259-68. 2001
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| 24 | ADAMTS4, ADAMTS5
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| TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5).
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| Kashiwagi M, Tortorella M, Nagase H, Brew K.
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| J Biol Chem 276(16):12501-4. 2001
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| 25 | ADAMTS1, ADAMTS2, ADAMTS5, ADAMTS6, ADAMTS7
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| ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.
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| Hurskainen TL, et al.
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| J Biol Chem 274(36):25555-63 1999
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| 26 | ADAMTS1, ADAMTS5
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| METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity.
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| Vazquez F, Hastings G, Ortega MA, Lane TF, Oikemus S, Lombardo M, Iruela-Arispe ML.
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| J Biol Chem 274(33):23349-57 1999
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| 27 | ADAMTS5
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| Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family.
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| Abbaszade I, Liu RQ, Yang F, Rosenfeld SA, Ross OH, Link JR, Ellis DM, Tortorella MD, Pratta MA, Hollis JM, Wynn R, Duke JL, George HJ, Hillman MC Jr, Murphy K, Wiswall BH, Copeland RA, Decicco CP, Bruckner R, Nagase H, Itoh Y, Newton RC, Magolda RL, Trzaskos JM, Burn TC, et al.
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| J Biol Chem 274(33):23443-50 1999
|