Citations for
1ADAM9, FGFR2, MMP14
MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.
Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z.
Dev Cell 22(6):1176-90. doi: 10.1016/j.devcel.2012.04.014. Epub 2012 May 24. 2012
2ACE, ADAM9
LPS activates ADAM9 dependent shedding of ACE from endothelial cells.
English WR, Corvol P, Murphy G.
Biochem Biophys Res Commun 421(1):70-5. doi: 10.1016/j.bbrc.2012.03.113. Epub 2012 Mar 29. 2012
3ADAM10, ADAM9
ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW.
J Biol Chem 286(47):40443-51. doi: 10.1074/jbc.M111.280495. Epub 2011 Sep 28. 2011
4ADAM9
The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts.
Zigrino P, Nischt R, Mauch C.
J Biol Chem 286(8):6801-7. doi: 10.1074/jbc.M110.168617. Epub 2010 Dec 6. 2011
5ADAM9
Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer's disease.
Cong L, Jia J.
Neurobiol Aging 32(1):54-62. doi: 10.1016/j.neurobiolaging.2009.01.001. Epub 2009 Feb 23. 2011
6ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
Regional expression of the ADAMs in developing chicken cochlea.
Yan X, Lin J, Wang H, Markus A, Wree A, Rolfs A, Luo J.
Dev Dyn 239(8):2256-65.PMID: 20658692 2010
7ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
Expression of seven members of the ADAM family in developing chicken spinal cord.
Lin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.
Dev Dyn 239(4):1246-54.PMID: 20235233 2010
8ADAM9, CORD12
An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9.
Goldstein O, Mezey JG, Boyko AR, Gao C, Wang W, Bustamante CD, Anguish LJ, Jordan JA, Pearce-Kelling SE, Aguirre GD, Acland GM.
Mol Vis 16:1549-69. 2010
9ADAM9
Secreted and membrane-bound isoforms of protease ADAM9 have opposing effects on breast cancer cell migration.
Fry JL, Toker A.
Cancer Res 70(20):8187-98. doi: 10.1158/0008-5472.CAN-09-4231. Epub 2010 Aug 24. 2010
10ADAM9, CORD12
Loss of the metalloprotease ADAM9 leads to cone-rod dystrophy in humans and retinal degeneration in mice.
Parry DA, Toomes C, Bida L, Danciger M, Towns KV, McKibbin M, Jacobson SG, Logan CV, Ali M, Bond J, Chance R, Swendeman S, Daniele LL, Springell K, Adams M, Johnson CA, Booth AP, Jafri H, Rashid Y, Banin E, Strom TM, Farber DB, Sharon D, Blobel CP, Pugh EN Jr, Pierce EA, Inglehearn CF.
Am J Hum Genet 84(5):683-91. Epub 2009 Apr 30. 2009
11ADAM10, ADAM15, ADAM9
ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
Tousseyn T, Thathiah A, Jorissen E, Raemaekers T, Konietzko U, Reiss K, Maes E, Snellinx A, Serneels L, Nyabi O, Annaert W, Saftig P, Hartmann D, De Strooper B.
J Biol Chem 284(17):11738-47. Epub 2009 Feb 11. 2009
12ADAM9
ADAM9 is involved in pathological retinal neovascularization.
Guaiquil V, Swendeman S, Yoshida T, Chavala S, Campochiaro PA, Blobel CP.
Mol Cell Biol 29(10):2694-703. Epub 2009 Mar 9. 2009
13ADAM9
Role of ADAM-9 disintegrin-cysteine-rich domains in human keratinocyte migration.
Zigrino P, Steiger J, Fox JW, Lffek S, Schild A, Nischt R, Mauch C.
J Biol Chem 282(42):30785-93. Epub 2007 Aug 17. 2007
14ADAM15, ADAM9
Increased expression of ADAM 9 and ADAM 15 mRNA in pancreatic cancer.
Yamada D, Ohuchida K, Mizumoto K, Ohhashi S, Yu J, Egami T, Fujita H, Nagai E, Tanaka M.
Anticancer Res 27(2):793-9. 2007
15ADAM9, ADAM12, ADAM15
The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer.
Carl-McGrath S, Lendeckel U, Ebert M, Roessner A, Rocken C.
Int J Oncol 26(1):17-24. 2005
16ADAM17,ADAM19,ADAM9
Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2.
Horiuchi K, Zhou HM, Kelly K, Manova K, Blobel CP.
Dev Biol 283(2):459-71. 2005
17ADAM9
Overexpression of ADAM9 in non-small cell lung cancer correlates with brain metastasis.
Shintani Y, Higashiyama S, Ohta M, Hirabayashi H, Yamamoto S, Yoshimasu T, Matsuda H, Matsuura N.
Cancer Res 64(12):4190-6. 2004
18ADAM9
Expression of ADAM-9 mRNA and protein in human breast cancer.
O'Shea C, McKie N, Buggy Y, Duggan C, Hill AD, McDermott E, O'Higgins N, Duffy MJ.
Int J Cancer 105(6):754-61. 2003
19ADAM9
A secreted form of human ADAM9 has an alpha-secretase activity for APP.
Hotoda N, Koike H, Sasagawa N, Ishiura S.
Biochem Biophys Res Commun 293(2):800-5. 2002
20TMPRSS5, ADAM9
ADAM-9 is an insulin-like growth factor binding protein-5 protease produced and secreted by human osteoblasts.
Mohan S, Thompson GR, Amaar YG, Hathaway G, Tschesche H, Baylink DJ.
Biochemistry 41(51):15394-403. 2002
21ADAM9
MDC-9 (ADAM-9/Meltrin gamma) functions as an adhesion molecule by binding the alpha(v)beta(5) integrin.
Zhou M, Graham R, Russell G, Croucher PI.
Biochem Biophys Res Commun 280(2):574-80. 2001
22ADAM15, ADAM9, SNX9
Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1.
Howard L, Nelson KK, Maciewicz RA, Blobel CP.
J Biol Chem 274(44):31693-9. 1999
23ADAM17, ADAM9, MAD2L1, MAD2L2
Evidence for an interaction of the metalloprotease-disintegrin tumour necrosis factor alpha convertase (TACE) with mitotic arrest deficient 2 (MAD2), and of the metalloprotease-disintegrin MDC9 with a novel MAD2-related protein, MAD2beta.
Nelson KK, Schlondorff J, Blobel CP.
Biochem J 343 Pt 3:673-80. 1999
24ADAM9
MDC9, a widely expressed cellular disintegrin containing cytoplasmic SH3 ligand domains.
Weskamp G, Kratzschmar J, Reid MS, Blobel CP.
J Cell Biol 132(4):717-26 1996
25ADAM9
Cloning of a novel membrane-linked metalloproteinase from human myeloma cells.
McKie N, Dallas DJ, Edwards T, Apperley JF, Russell RG, Croucher PI.
Biochem J 318 ( Pt 2):459-62 1996