| 1 | ADAM22, LGI3
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| LGI3 is secreted and binds to ADAM22 via TRIF-dependent NF-κB pathway in response to LPS in human keratinocytes
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| Lee SH, Kwon NS, Baek KJ, Yun HY, Kim DS.
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| Cytokine. Feb;126:154872. doi: 10.1016/j.cyto.2019.154872. Epub 2019 Oct 15 2020
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| 2 | ADAM22, ADAM23, LGI1
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| ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment
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| Hivert B, Marien L, Agbam KN, Faivre-Sarrailh C.
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| J Cell Sci. Jan 16;132(2):jcs219774. doi: 10.1242/jcs.219774. 2019
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| 3 | ADAM22, LCCS12, LGI4
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| Loss-of-Function Mutations in LGI4, a Secreted Ligand Involved in Schwann Cell Myelination, Are Responsible for Arthrogryposis Multiplex Congenita.
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| Xue S, Maluenda J, Marguet F, Shboul M, Quevarec L, Bonnard C, Ng AY, Tohari S, Tan TT, Kong MK, Monaghan KG, Cho MT, Siskind CE, Sampson JB, Rocha CT, Alkazaleh F, Gonzales M, Rigonnot L, Whalen S, Gut M, Gut I, Bucourt M, Venkatesh B, Laquerrière A, Reversade B, Melki J.
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| Am J Hum Genet 100(4):659-665. doi: 10.1016/j.ajhg.2017.02.006. Epub 2017 Mar 16. 2017
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| 4 | ADAM22, LGI1
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| The LGI1-ADAM22 protein complex in synaptic transmission and synaptic disorders.
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| Fukata Y, Yokoi N, Miyazaki Y, Fukata M.
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| Neurosci Res 116:39-45. doi: 10.1016/j.neures.2016.09.011. Epub 2016 Oct 4. Review.
2017
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| 5 | ADAM22, ADAM23, LGI3
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| Leucine-rich glioma inactivated 3: integrative analyses support its prognostic role in glioma.
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| Kwon NS, Kim DS, Yun HY.
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| Onco Targets Ther. May 24;10:2721-2728. doi: 10.2147/OTT.S138912. 2017
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| 6 | ADAM22, ADAM23, EPT, LGI1
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| Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors.
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| Dazzo E, Leonardi E, Belluzzi E, Malacrida S, Vitiello L, Greggio E, Tosatto SC, Nobile C.
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| PLoS Genet 12(10):e1006376. doi: 10.1371/journal.pgen.1006376. eCollection 2016 Oct.
2016
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| 7 | ADAM22, EIEECA
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| Dysfunctional ADAM22 implicated in progressive encephalopathy with cortical atrophy and epilepsy.
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| Muona M, Fukata Y, Anttonen AK, Laari A, Palotie A, Pihko H, Lönnqvist T, Valanne L, Somer M, Fukata M, Lehesjoki AE.
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| Neurol Genet 2(1):e46. doi: 10.1212/NXG.0000000000000046. eCollection 2016 Feb.
2016
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| 8 | ADAM22, DLG4, LGI1
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| The LGI1-ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function.
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| Lovero KL, Fukata Y, Granger AJ, Fukata M, Nicoll RA.
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| Proc Natl Acad Sci U S A 112(30):E4129-37. doi: 10.1073/pnas.1511910112. Epub 2015 Jul 15.
2015
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| 9 | ADAM22, LGI1
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| Autoantibodies to epilepsy-related LGI1 in limbic encephalitis neutralize LGI1-ADAM22 interaction and reduce synaptic AMPA receptors.
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| Ohkawa T, Fukata Y, Yamasaki M, Miyazaki T, Yokoi N, Takashima H, Watanabe M, Watanabe O, Fukata M.
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| J Neurosci 33(46):18161-74. doi: 10.1523/JNEUROSCI.3506-13.2013.
2013
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| 10 | ADAM12, ADAM22
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| Differential regional expression of multiple ADAMs during feather bud formation.
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| Lin J, Luo J, Redies C.
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| Dev Dyn 240(9):2142-52. doi: 10.1002/dvdy.22703. Epub 2011 Jul 20.
2011
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| 11 | ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
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| Regional expression of the ADAMs in developing chicken cochlea.
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| Yan X, Lin J, Wang H, Markus A, Wree A, Rolfs A, Luo J.
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| Dev Dyn 239(8):2256-65.PMID: 20658692 2010
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| 12 | ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
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| Expression of seven members of the ADAM family in developing chicken spinal cord.
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| Lin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.
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| Dev Dyn 239(4):1246-54.PMID: 20235233 2010
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| 13 | ADAM22, LGI4
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| Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling.
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| Ozkaynak E, Abello G, Jaegle M, van Berge L, Hamer D, Kegel L, Driegen S, Sagane K, Bermingham JR Jr, Meijer D.
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| J Neurosci 30(10):3857-64. doi: 10.1523/JNEUROSCI.6287-09.2010.
2010
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| 14 | ADAM22, LGI1
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| Structural characterization of the ectodomain of a disintegrin and metalloproteinase-22 (ADAM22), a neural adhesion receptor instead of metalloproteinase: insights on ADAM function.
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| Liu H, Shim AH, He X.
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| J Biol Chem 284(42):29077-86. Epub 2009 Aug 18.PMID: 19692335 2009
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| 15 | ADAM11, ADAM22, ADAM23, LGI1, LGI4
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| LGI1 and LGI4 bind to ADAM22, ADAM23 and ADAM11.
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| Sagane K, Ishihama Y, Sugimoto H.
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| Int J Biol Sci 4(6):387-96. Epub 2008 Oct 21.PMID: 18974846 2008
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| 16 | ADAM22, LGI1
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| Autosomal dominant lateral temporal epilepsy: absence of mutations in ADAM22 and Kv1 channel genes encoding LGI1-associated proteins.
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| Diani E, Di Bonaventura C, Mecarelli O, Gambardella A, Elia M, Bovo G, Bisulli F, Pinardi F, Binelli S, Egeo G, Castellotti B, Striano P, Striano S, Bianchi A, Ferlazzo E, Vianello V, Coppola G, Aguglia U, Tinuper P, Giallonardo AT, Michelucci R, Nobile C.
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| Epilepsy Res 80(1):1-8. Epub 2008 Apr 28.PMID: 18440780 2008
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| 17 | ADAM22
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| Differential coding potential of ADAM22 mRNAs.
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| Gšdde NJ, D'Abaco GM, Paradiso L, Novak U.
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| Gene 403(1-2):80-8. Epub 2007 Aug 23. 2007
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| 18 | LGI1, ADAM22
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| Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission.
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| Fukata Y, Adesnik H, Iwanaga T, Bredt DS, Nicoll RA, Fukata M.
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| Science 313(5794):1792-5. 2006
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| 19 | ADAM11, ADAM22
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| ADAM22, expressed in normal brain but not in high-grade gliomas, inhibits cellular proliferation via the disintegrin domain.
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| D'Abaco GM, Ng K, Paradiso L, Godde NJ, Kaye A, Novak U.
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| Neurosurgery 58(1):179-86; discussion 179-86. 2006
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| 20 | YWHAZ, ADAM22
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| ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3.
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| Zhu P, Sang Y, Xu H, Zhao J, Xu R, Sun Y, Xu T, Wang X, Chen L, Feng H, Li C, Zhao S.
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| Biochem Biophys Res Commun 331(4):938-46. 2005
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| 21 | USP9X, ADAM22
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| Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.
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| Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL.
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| Genomics 84(1):205-10. 2004
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| 22 | ADAM21, ADAM22, ADAM23
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| The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries.
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| Poindexter K, Nelson N, DuBose RF, Black RA, Cerretti DP.
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| Gene 237(1):61-70 1999
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| 23 | ABCB1, ABCB4, ADAM22, DMTF1, CROT, NADHDL1, SCNEDL, SRI
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| Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1.
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| Torigoe K, et al.
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| Genomics 49 : 14-22. 1998
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| 24 | ADAM22, ADAM23
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| Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain.
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| Sagane K, Ohya Y, Hasegawa Y, Tanaka I.
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| Biochem J 334 ( Pt 1):93-8 1998
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