| 1 | ADAM12, TSPAN9
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| ADAM12 is A Potential Therapeutic Target Regulated by Hypomethylation in Triple-Negative Breast Cancer
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| Mendaza S, Ulazia-Garmendia A, Monreal-Santesteban I, Córdoba A, Azúa YR, Aguiar B, Beloqui R, Armendáriz P, Arriola M, Martín-Sánchez E, Guerrero-Setas D.
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| Int J Mol Sci. Jan 30;21(3):903. doi: 10.3390/ijms21030903. 2020
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| 2 | ADAM12
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| Predictive value of biochemical marker ADAM-12 at first trimester of pregnancy for hypertension and intrauterine growth restriction.
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| Kasimis C, Evangelinakis N, Rotas M, Georgitsi M, Pelekanos N, Kassanos D.
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| Clin Exp Obstet Gynecol 43(1):43-7.
2016
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| 3 | ADAM12
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| The Disintegrin and Metalloprotease ADAM12 Is Associated with TGF-β-Induced Epithelial to Mesenchymal Transition.
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| Ruff M, Leyme A, Le Cann F, Bonnier D, Le Seyec J, Chesnel F, Fattet L, Rimokh R, Baffet G, Théret N.
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| PLoS One 10(9):e0139179. doi: 10.1371/journal.pone.0139179.
2015
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| 4 | ADAM12, ADAM17
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| ADAM12 and ADAM17 are essential molecules for hypoxia-induced impairment of neural vascular barrier function.
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| Cui D, Arima M, Takubo K, Kimura T, Horiuchi K, Minagawa T, Matsuda S, Ikeda E.
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| Sci Rep 5:12796. doi: 10.1038/srep12796.
2015
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| 5 | ADAM12
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| ADAM12: a genetic modifier of preclinical peripheral arterial disease.
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| Dokun AO, Chen L, Okutsu M, Farber CR, Hazarika S, Jones WS, Craig D, Marchuk DA, Lye RJ, Shah SH, Annex BH.
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| Am J Physiol Heart Circ Physiol 309(5):H790-803. doi: 10.1152/ajpheart.00803.2014.
2015
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| 6 | ADAM12, CDH1
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| ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.
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| Aghababaei M, Hogg K, Perdu S, Robinson WP, Beristain AG.
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| Cell Death Differ 22(12):1970-84. doi: 10.1038/cdd.2015.44.
2015
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| 7 | ADAM12, LCN2, MMP9
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| Urinary ADAM12 and MMP-9/NGAL complex detect the presence of gastric cancer.
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| Shimura T, Dagher A, Sachdev M, Ebi M, Yamada T, Yamada T, Joh T, Moses MA.
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| Cancer Prev Res (Phila) 8(3):240-8. doi: 10.1158/1940-6207.CAPR-14-0229.
2015
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| 8 | ADAM12, BSG
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| EMMPRIN and ADAM12 in prostate cancer: preliminary results of a prospective study.
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| Bilgin Doğru E, Dizdar Y, Akşit E, Ural F, Şanlı Ö, Yasasever V.
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| Tumour Biol 35(11):11647-53. doi: 10.1007/s13277-014-2514-8.
2014
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| 9 | ADAM12
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| Maternal serum disintegrin and metalloprotease protein-12 in early pregnancy as a potential marker of adverse pregnancy outcomes.
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| Yang J, Wu J, Guo F, Wang D, Chen K, Li J, Du L, Yin A.
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| PLoS One 9(5):e97284. doi: 10.1371/journal.pone.0097284.
2014
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| 10 | ADAM12
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| Extravillous trophoblast-associated ADAM12 exerts pro-invasive properties, including induction of integrin beta 1-mediated cellular spreading.
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| Biadasiewicz K, Fock V, Dekan S, Proestling K, Velicky P, Haider S, Knöfler M, Fröhlich C, Pollheimer J.
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| Biol Reprod 90(5):101. doi: 10.1095/biolreprod.113.115279.
2014
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| 11 | ADAM12
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| A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.
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| Aghababaei M, Perdu S, Irvine K, Beristain AG.
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| Mol Hum Reprod 20(3):235-49. doi: 10.1093/molehr/gat084.
2014
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| 12 | ADAM12, EPHA1
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| ADAM12-cleaved ephrin-A1 contributes to lung metastasis.
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| Ieguchi K, Tomita T, Omori T, Komatsu A, Deguchi A, Masuda J, Duffy SL, Coulthard MG, Boyd A, Maru Y.
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| Oncogene ncogene. 2013 May 20. doi: 10.1038/onc.2013.180. [Epub ahead of print]
2013
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| 13 | ADAM12
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| Metalloproteinase-disintegrin ADAM12 is associated with a breast tumor-initiating cell phenotype.
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| Li H, Duhachek-Muggy S, Dubnicka S, Zolkiewska A.
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| Breast Cancer Res Treat 139(3):691-703. doi: 10.1007/s10549-013-2602-2.
2013
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| 14 | ADAM12
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| A disintegrin and metalloproteinase-12 (ADAM12): function, roles in disease progression, and clinical implications.
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| Nyren-Erickson EK, Jones JM, Srivastava DK, Mallik S.
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| Biochim Biophys Acta 1830(10):4445-55. doi: 10.1016/j.bbagen.2013.05.011. Review.
2013
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| 15 | ADAM12
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| ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.
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| Fröhlich C, Klitgaard M, Noer JB, Kotzsch A, Nehammer C, Kronqvist P, Berthelsen J, Blobel C, Kveiborg M, Albrechtsen R, Wewer UM.
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| Biochem J 452(1):97-109. doi: 10.1042/BJ20121558.
2013
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| 16 | ADAM12, ILK
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| Identification of ILK as a new partner of the ADAM12 disintegrin and metalloprotease in cell adhesion and survival.
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| Leyme A, Bourd-Boittin K, Bonnier D, Falconer A, Arlot-Bonnemains Y, Théret N.
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| Mol Biol Cell 23(17):3461-72. doi: 10.1091/mbc.E11-11-0918. Epub 2012 Jul 5.
2012
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| 17 | ADAM12
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| Cell-surface metalloprotease ADAM12 is internalized by a clathrin- and Grb2-dependent mechanism.
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| Stautz D, Leyme A, Grandal MV, Albrechtsen R, van Deurs B, Wewer U, Kveiborg M.
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| Traffic 13(11):1532-46. doi: 10.1111/j.1600-0854.2012.01405.x.
2012
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| 18 | ADAM12, ERBB2
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| A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
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| Rao VH, Kandel A, Lynch D, Pena Z, Marwaha N, Deng C, Watson P, Hansen LA.
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| Oncogene 31(23):2888-98. doi: 10.1038/onc.2011.460. Epub 2011 Oct 10.
2012
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| 19 | ADAM12
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| Exosome release of ADAM15 and the functional implications of human macrophage-derived ADAM15 exosomes.
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| Lee HD, Koo BH, Kim YH, Jeon OH, Kim DS.
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| FASEB J 26(7):3084-95. doi: 10.1096/fj.11-201681. Epub 2012 Apr 13.
2012
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| 20 | ADAM12
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| Extracellular engagement of ADAM12 induces clusters of invadopodia with localized ectodomain shedding activity.
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| Albrechtsen R, Stautz D, Sanjay A, Kveiborg M, Wewer UM.
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| Exp Cell Res 317(2):195-209. Epub 2010 Oct 14.
2011
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| 21 | ADAM12
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| ADAM12 transmembrane and secreted isoforms promote breast tumor growth: a distinct role for ADAM12-S protein in tumor metastasis.
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| Roy R, Rodig S, Bielenberg D, Zurakowski D, Moses MA.
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| J Biol Chem 286(23):20758-68. Epub 2011 Apr 14.
2011
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| 22 | ADAM12, ADAM22
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| Differential regional expression of multiple ADAMs during feather bud formation.
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| Lin J, Luo J, Redies C.
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| Dev Dyn 240(9):2142-52. doi: 10.1002/dvdy.22703. Epub 2011 Jul 20.
2011
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| 23 | ADAM12, ADAM17, TIMP2
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| Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2).
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| Kveiborg M, Jacobsen J, Lee MH, Nagase H, Wewer UM, Murphy G.
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| Biochem J 430(1):79-86.
2010
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| 24 | ADAM12, SKIL
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| The role of SnoN in transforming growth factor beta1-induced expression of metalloprotease-disintegrin ADAM12.
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| Solomon E, Li H, Duhachek Muggy S, Syta E, Zolkiewska A.
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| J Biol Chem 285(29):21969-77. doi: 10.1074/jbc.M110.133314. Epub 2010 May 10.
2010
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| 25 | ADAM12, SH3PXD2A
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| A study of the association between the ADAM12 and SH3PXD2A (SH3MD1) genes and Alzheimer's disease.
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| Laumet G, Petitprez V, Sillaire A, Ayral AM, Hansmanel F, Chapuis J, Hannequin D, Pasquier F, Scarpini E, Galimberti D, Lendon C, Campion D, Amouyel P, Lambert JC.
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| Neurosci Lett eurosci Lett. 2009 Oct 15. [Epub ahead of print]
2009
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| 26 | ADAM12, RACK1
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| RACK1, a new ADAM12 interacting protein. Contribution to liver fibrogenesis.
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| Bourd-Boittin K, Le Pabic H, Bonnier D, L'Helgoualc'h A, Théret N.
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| J Biol Chem 283(38):26000-9. Epub 2008 Jul 11. 2008
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| 27 | ADAM12
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| Heparan sulfate regulates ADAM12 through a molecular switch mechanism.
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| Sørensen HP, Vivès RR, Manetopoulos C, Albrechtsen R, Lydolph MC, Jacobsen J, Couchman JR, Wewer UM.
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| J Biol Chem 283(46):31920-32. Epub 2008 Sep 17.
2008
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| 28 | ADAM12, TSPAN8
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| TM4SF3 promotes esophageal carcinoma metastasis via upregulating ADAM12m expression.
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| Zhou Z, Ran YL, Hu H, Pan J, Li ZF, Chen LZ, Sun LC, Peng L, Zhao XL, Yu L, Sun LX, Yang ZH.
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| Clin Exp Metastasis 25(5):537-48. Epub 2008 Mar 26.PMID: 18365756 2008
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| 29 | ADAM12
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| ADAM12: a potential target for the treatment of chronic wounds.
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| Harsha A, Stojadinovic O, Brem H, Sehara-Fujisawa A, Wewer U, Loomis CA, Blobel CP, Tomic-Canic M.
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| J Mol Med 86(8):961-9. Epub 2008 Jul 5.PMID: 18604515 2008
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| 30 | ADAM12, SH3PXD2A
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| Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease.
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| Harold D, Jehu L, Turic D, Hollingworth P, Moore P, Summerhayes P, Moskvina V, Foy C, Archer N, Hamilton BA, Lovestone S, Powell J, Brayne C, Rubinsztein DC, Jones L, O'Donovan MC, Owen MJ, Williams J.
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| Am J Med Genet B Neuropsychiatr Genet 144B(4):448-52.
2007
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| 31 | ADAM9, ADAM12, ADAM15
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| The disintegrin-metalloproteinases ADAM9, ADAM12, and ADAM15 are upregulated in gastric cancer.
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| Carl-McGrath S, Lendeckel U, Ebert M, Roessner A, Rocken C.
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| Int J Oncol 26(1):17-24. 2005
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| 32 | ADAM12
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| Role of meltrin {alpha} (ADAM12) in obesity induced by high- fat diet.
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| Masaki M, Kurisaki T, Shirakawa K, Sehara-Fujisawa A.
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| Endocrinology 146(4):1752-63. Epub 2005 Jan 6. 2005
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| 33 | ADAM12,ITGB1,ITGB3
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| ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.
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| Thodeti CK, Frohlich C, Nielsen CK, Takada Y, Fassler R, Albrechtsen R, Wewer UM.
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| FEBS Lett 579(25):5589-95. Epub 2005 Sep 28. 2005
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| 34 | ADAM12, SH3PXD2A
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| Amyloid-beta neurotoxicity is mediated by FISH adapter protein and ADAM12 metalloprotease activity.
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| Malinin NL, Wright S, Seubert P, Schenk D, Griswold-Prenner I.
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| Proc Natl Acad Sci U S A 102(8):3058-63. Epub 2005 Feb 14.
2005
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| 35 | ADAM12
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| ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage.
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| Roy R, Wewer UM, Zurakowski D, Pories SE, Moses MA.
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| J Biol Chem 279(49):51323-30. Epub 2004 Sep 20. 2004
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| 36 | ADAM12
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| Intracellular processing of metalloprotease disintegrin ADAM12.
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| Cao Y, Kang Q, Zhao Z, Zolkiewska A.
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| J Biol Chem 277(29):26403-11. Epub 2002 May 08. 2002
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| 37 | ADAM12
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| Metalloprotease-disintegrin ADAM 12 interacts with alpha-actinin-1.
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| Cao Y, Kang Q, Zolkiewska A.
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| Biochem J 357(Pt 2):353-61. 2001
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| 38 | ADAM12
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| Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion.
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| Galliano MF, Huet C, Frygelius J, Polgren A, Wewer UM, Engvall E.
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| J Biol Chem 275(18):13933-9. 2000
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| 39 | ADAM12, IGFBP3
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| ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3.
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| Shi Z, Xu W, Loechel F, Wewer UM, Murphy LJ.
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| J Biol Chem 275(24):18574-80. 2000
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| 40 | ADAM12
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| Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion.
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| Iba K, et al.
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| Am J Pathol 154(5):1489-501. 1999
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| 41 | ADAM12
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| Human ADAM 12 (meltrin alpha) is an active metalloprotease.
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| Loechel F, et al.
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| J Biol Chem 273 : 16993-16997. 1998
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| 42 | ADAM12
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| A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.
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| Gilpin BJ, Loechel F, Mattei MG, Engvall E, Albrechtsen R, Wewer UM.
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| J Biol Chem 273(1):157-66. 1998
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| 43 | ADAM12
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| A metalloprotease-disintegrin participating in myoblast fusion.
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| Yagami-Hiromasa T, et al.
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| Nature 377 : 652-656. 1995
|