| 1 | ADAM10, TACSTD2
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| Trop-2 cleavage by ADAM10 is an activator switch for cancer growth and metastasis.
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| Trerotola M, Guerra E, Ali Z, Aloisi AL, Ceci M, Simeone P, Acciarito A, Zanna P, Vacca G, D'Amore A, Boujnah K, Garbo V, Moschella A, Lattanzio R, Alberti S.
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| Neoplasia. Apr;23(4):415-428. doi: 10.1016/j.neo.2021.03.006. Epub 2021 Apr 8. 2021
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| 2 | ADAM10, RELT
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| ADAM10 is Expressed by Ameloblasts, Cleaves the RELT TNF Receptor Extracellular Domain and Facilitates Enamel Development.
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| Ikeda A, Shahid S, Blumberg BR, Suzuki M, Bartlett JD.
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| Sci Rep 9(1):14086. doi: 10.1038/s41598-019-50277-y.
2019
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| 3 | ADAM10, NRCAM
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| NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease
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| Brummer T, Müller SA, Pan-Montojo F, Yoshida F, Fellgiebel A, Tomita T, Endres K, Lichtenthaler SF
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| EMBO Mol Med. Apr;11(4):e9695. doi: 10.15252/emmm.201809695. 2019
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| 4 | ADAM10, TSPAN10, TSPAN14, TSPAN15, TSPAN17, TSPAN33, TSPAN5
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| Regulation of the trafficking and the function of the metalloprotease ADAM10 by tetraspanins.
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| Saint-Pol J, Eschenbrenner E, Dornier E, Boucheix C, Charrin S, Rubinstein E.
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| Biochem Soc Trans 45(4):937-44. doi: 10.1042/BST20160296. Epub 2017 Jul 7. Review.
2017
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| 5 | ADAM10, TSPAN10, TSPAN14, TSPAN15, TSPAN17, TSPAN33, TSPAN5
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| Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins.
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| Matthews AL, Szyroka J, Collier R, Noy PJ, Tomlinson MG.
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| Biochem Soc Trans 45(3):719-730. doi: 10.1042/BST20160290. Review.
2017
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| 6 | ADAM10, ADAM17, TSPAN10, TSPAN14, TSPAN15, TSPAN17, TSPAN33, TSPAN5
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| Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids.
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| Matthews AL, Noy PJ, Reyat JS, Tomlinson MG.
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| Platelets 28(4):333-341. doi: 10.1080/09537104.2016.1184751. Epub 2016 Jun 2. Review.
2017
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| 7 | ADAM10, CDH5, TSPAN17, TSPAN5
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| ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration.
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| Reyat JS, Chimen M, Noy PJ, Szyroka J, Rainger GE, Tomlinson MG.
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| J Immunol 199(2):666-676. doi: 10.4049/jimmunol.1600713. Epub 2017 Jun 9.
2017
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| 8 | ADAM10, LSAMP
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| Ectodomain shedding of Limbic System-Associated Membrane Protein (LSAMP) by ADAM Metallopeptidases promotes neurite outgrowth in DRG neurons.
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| Sanz RL, Ferraro GB, Girouard MP, Fournier AE.
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| Sci Rep. Aug 11;7(1):7961. doi: 10.1038/s41598-017-08315-0 2017
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| 9 | ADAM10, DTX4, NOTCH1
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| Ligand-activated Notch undergoes DTX4-mediated ubiquitylation and bilateral endocytosis before ADAM10 processing.
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| Chastagner P, Rubinstein E, Brou C.
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| Sci Signal. Jun 13;10(483):eaag2989. doi: 10.1126/scisignal.aag2989 2017
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| 10 | ADAM10, TSPAN3
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| Tetraspanin 3: A central endocytic membrane component regulating the expression of ADAM10, presenilin and the amyloid precursor protein
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| Seipold L, Damme M, Prox J, Rabe B, Kasparek P, Sedlacek R, Altmeppen H, Willem M, Boland B, Glatzel M, Saftig P.
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| Biochim Biophys Acta Mol Cell Res. Jan;1864(1):217-230. doi: 10.1016/j.bbamcr.2016.11.003. Epub 2016 Nov 3. 2017
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| 11 | ADAM10, TSPAN14, TSPAN15
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| TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS.
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| Noy PJ, Yang J, Reyat JS, Matthews AL, Charlton AE, Furmston J, Rogers DA, Rainger GE, Tomlinson MG.
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| J Biol Chem 291(7):3145-57. doi: 10.1074/jbc.M115.703058. Epub 2015 Dec 14.
2016
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| 12 | ADAM10, TSPAN10, TSPAN14, TSPAN15, TSPAN17, TSPAN33, TSPAN5
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| TspanC8 tetraspanins differentially regulate the cleavage of ADAM10 substrates, Notch activation and ADAM10 membrane compartmentalization.
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| Jouannet S, Saint-Pol J, Fernandez L, Nguyen V, Charrin S, Boucheix C, Brou C, Milhiet PE, Rubinstein E.
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| Cell Mol Life Sci 73(9):1895-915. doi: 10.1007/s00018-015-2111-z. Epub 2015 Dec 19.
2016
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| 13 | ADAM10, CTF1, MAZ, NOTCH1
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| MAZ mediates the cross-talk between CT-1 and NOTCH1 signaling during gliogenesis.
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| Liu B, Ma A, Zhang F, Wang Y, Li Z, Li Q, Xu Z, Zheng Y.
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| Sci Rep 6:21534. doi: 10.1038/srep21534. Erratum in: Sci Rep. 2016;6:23309.
2016
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| 14 | ADAM10, FGFR2, NEGR1
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| The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2.
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| Pischedda F, Piccoli G.
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| Front Mol Neurosci. Jan 13;8:89. doi: 10.3389/fnmol.2015.00089. eCollection 2015 2016
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| 15 | ADAM10, APP, FRAXA
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| Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome.
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| Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, Bagni C.
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| Neuron 87(2):382-98. doi: 10.1016/j.neuron.2015.06.032.
2015
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| 16 | ADAM10, ADAM17, FASLG
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| Subcellular localization and activation of ADAM proteases in the context of FasL shedding in T lymphocytes.
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| Ebsen H, Lettau M, Kabelitz D, Janssen O.
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| Mol Immunol 65(2):416-28. doi: 10.1016/j.molimm.2015.02.008. Epub 2015 Mar 5.
2015
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| 17 | ADAM10, TNFRSF13B
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| The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
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| Hoffmann FS, Kuhn PH, Laurent SA, Hauck SM, Berer K, Wendlinger SA, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister HW, Alexander T, Hiepe F, Kümpfel T, Crawford HC, Wekerle H, Hohlfeld R, Lichtenthaler SF, Meinl E.
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| J Immunol 194(2):542-52. doi: 10.4049/jimmunol.1402070. Epub 2014 Dec 10.
2015
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| 18 | ADAM10, ADAM17
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| ADAM10 and ADAM17 have opposite roles during sprouting angiogenesis.
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| Caolo V, Swennen G, Chalaris A, Wagenaar A, Verbruggen S, Rose-John S, Molin DG, Vooijs M, Post MJ.
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| Angiogenesis 18(1):13-22. doi: 10.1007/s10456-014-9443-4. Epub 2014 Sep 14.
2015
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| 19 | ADAM10, BTC
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| The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.
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| Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP.
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| J Biol Chem 290(12):7416-25. doi: 10.1074/jbc.M114.603753. Epub 2015 Jan 20.
2015
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| 20 | ADAM10, GNA12, PKD1
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| Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.
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| Xu JX, Lu TS, Li S, Wu Y, Ding L, Denker BM, Bonventre JV, Kong T.
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| Physiol Genomics 47(2):24-32. doi: 10.1152/physiolgenomics.00090.2014. Epub 2014 Dec 9.
2015
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| 21 | ADAM10, BACE1
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| ADAM10 and BACE1 are localized to synaptic vesicles.
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| Lundgren JL, Ahmed S, Schedin-Weiss S, Gouras GK, Winblad B, Tjernberg LO, Frykman S.
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| J Neurochem 135(3):606-15. doi: 10.1111/jnc.13287. Epub 2015 Sep 17.
2015
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| 22 | ADAM10, DLL4, HES1, HEY1
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| The disintegrin and metalloproteinase ADAM10 mediates a canonical Notch-dependent regulation of IL-6 through Dll4 in human endothelial cells.
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| Pabois A, Devallière J, Quillard T, Coulon F, Gérard N, Laboisse C, Toquet C, Charreau B.
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| Biochem Pharmacol 91(4):510-21. doi: 10.1016/j.bcp.2014.08.007. Epub 2014 Aug 15.
2014
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| 23 | ADAM10, DLG1
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| SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation.
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| Saraceno C, Marcello E, Di Marino D, Borroni B, Claeysen S, Perroy J, Padovani A, Tramontano A, Gardoni F, Di Luca M.
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| Cell Death Dis 5:e1547. doi: 10.1038/cddis.2014.492.
2014
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| 24 | ADAM10
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| ADAM10 regulates Notch function in intestinal stem cells of mice.
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| Tsai YH, VanDussen KL, Sawey ET, Wade AW, Kasper C, Rakshit S, Bhatt RG, Stoeck A, Maillard I, Crawford HC, Samuelson LC, Dempsey PJ.
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| Gastroenterology 147(4):822-834.e13. doi: 10.1053/j.gastro.2014.07.003. Epub 2014 Jul 16.
2014
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| 25 | ADAM10
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| ADAM10 is required for SCF-induced mast cell migration.
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| Faber TW, Pullen NA, Fernando JF, Kolawole EM, McLeod JJ, Taruselli M, Williams KL, Rivera KO, Barnstein BO, Conrad DH, Ryan JJ.
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| Cell Immunol 290(1):80-8. doi: 10.1016/j.cellimm.2014.05.005. Epub 2014 May 21.
2014
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| 26 | ADAM10
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| ADAM10 negatively regulates neuronal differentiation during spinal cord development.
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| Yan X, Lin J, Talabattula VA, Mußmann C, Yang F, Wree A, Rolfs A, Luo J.
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| PLoS One 9(1):e84617. doi: 10.1371/journal.pone.0084617. eCollection 2014.
2014
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| 27 | ADAM10, RAK
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| Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease.
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| Kono M, Sugiura K, Suganuma M, Hayashi M, Takama H, Suzuki T, Matsunaga K, Tomita Y, Akiyama M.
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| Hum Mol Genet 22(17):3524-33. doi: 10.1093/hmg/ddt207. Epub 2013 May 10.
2013
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| 28 | ADAM10, CXCL16, P2RX7
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| Human P2X7 receptor activation induces the rapid shedding of CXCL16.
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| Pupovac A, Foster CM, Sluyter R.
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| Biochem Biophys Res Commun 432(4):626-31. doi: 10.1016/j.bbrc.2013.01.134. Epub 2013 Feb 18.
2013
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| 29 | ADAM10
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| ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function.
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| Suh J, Choi SH, Romano DM, Gannon MA, Lesinski AN, Kim DY, Tanzi RE.
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| Neuron 80(2):385-401. doi: 10.1016/j.neuron.2013.08.035. Epub 2013 Sep 19.
2013
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| 30 | ADAM10
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| Postnatal disruption of the disintegrin/metalloproteinase ADAM10 in brain causes epileptic seizures, learning deficits, altered spine morphology, and defective synaptic functions.
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| Prox J, Bernreuther C, Altmeppen H, Grendel J, Glatzel M, D'Hooge R, Stroobants S, Ahmed T, Balschun D, Willem M, Lammich S, Isbrandt D, Schweizer M, Horré K, De Strooper B, Saftig P.
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| J Neurosci 33(32):12915-28, 12928a. doi: 10.1523/JNEUROSCI.5910-12.2013.
2013
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| 31 | ADAM10
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| ADAM10 mediates N-cadherin ectodomain shedding during retinal ganglion cell differentiation in primary cultured retinal cells from the developing chick retina.
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| Paudel S, Kim YH, Huh MI, Kim SJ, Chang Y, Park YJ, Lee KW, Jung JC.
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| J Cell Biochem 114(4):942-54. doi: 10.1002/jcb.24435.
2013
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| 32 | ADAM10, AGER, MMP9
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| Induction of RAGE shedding by activation of G protein-coupled receptors.
|
| Metz VV, Kojro E, Rat D, Postina R.
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| PLoS One 7(7):e41823. doi: 10.1371/journal.pone.0041823. Epub 2012 Jul 30.
2012
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| 33 | ADAM10, CADM1
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| Tumor suppressor cell adhesion molecule 1 (CADM1) is cleaved by a disintegrin and metalloprotease 10 (ADAM10) and subsequently cleaved by γ-secretase complex.
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| Nagara Y, Hagiyama M, Hatano N, Futai E, Suo S, Takaoka Y, Murakami Y, Ito A, Ishiura S.
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| Biochem Biophys Res Commun 417(1):462-7. doi: 10.1016/j.bbrc.2011.11.140. Epub 2011 Dec 7.
2012
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| 34 | ADAM10, ADAM17, SIGMAR1
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| Overexpression of sigma-1 receptor inhibits ADAM10 and ADAM17 mediated shedding in vitro.
|
| Li J, Liu B, Gao X, Ma Z, CaoSong T, Mei YA, Zheng Y.
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| Protein Cell 3(2):153-9. doi: 10.1007/s13238-012-2006-9. Epub 2012 Feb 9. Erratum in: Protein Cell. 2012 May;3(5):400.
2012
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| 35 | ADAM10, TSPAN15
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| Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10.
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| Prox J, Willenbrock M, Weber S, Lehmann T, Schmidt-Arras D, Schwanbeck R, Saftig P, Schwake M.
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| Cell Mol Life Sci 69(17):2919-32. doi: 10.1007/s00018-012-0960-2. Epub 2012 Mar 25.
2012
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| 36 | ADAM10, TSPAN10, TSPAN14, TSPAN15, TSPAN17, TSPAN33, TSPAN5
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| The TspanC8 subgroup of tetraspanins interacts with A disintegrin and metalloprotease 10 (ADAM10) and regulates its maturation and cell surface expression.
|
| Haining EJ, Yang J, Bailey RL, Khan K, Collier R, Tsai S, Watson SP, Frampton J, Garcia P, Tomlinson MG.
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| J Biol Chem 287(47):39753-65. doi: 10.1074/jbc.M112.416503. Epub 2012 Oct 3.
2012
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| 37 | ADAM10, PCDH12
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| Protocadherin-12 cleavage is a regulated process mediated by ADAM10 protein: evidence of shedding up-regulation in pre-eclampsia.
|
| Bouillot S, Tillet E, Carmona G, Prandini MH, Gauchez AS, Hoffmann P, Alfaidy N, Cand F, Huber P.
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| J Biol Chem 286(17):15195-204. Epub 2011 Mar 14.
2011
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| 38 | ADAM10, SFRP1, SFRP2
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| SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis.
|
| Esteve P, Sandonìs A, Cardozo M, Malapeira J, Ibañez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P.
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| Nat Neurosci 14(5):562-9. Epub 2011 Apr 10.
2011
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| 39 | ADAM10, CDH1, EPHB1, EPHB3
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| Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling.
|
| Solanas G, Cortina C, Sevillano M, Batlle E.
|
| Nat Cell Biol 13(9):1100-7. doi: 10.1038/ncb2298.
2011
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| 40 | ADAM10
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| Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway.
|
| Armanious H, Gelebart P, Anand M, Belch A, Lai R.
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| Blood 117(23):6237-46. Epub 2011 Mar 25.
2011
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| 41 | ADAM10, BACE1, NRG1
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| Cleavage of neuregulin-1 by BACE1 or ADAM10 protein produces differential effects on myelination.
|
| Luo X, Prior M, He W, Hu X, Tang X, Shen W, Yadav S, Kiryu-Seo S, Miller R, Trapp BD, Yan R.
|
| J Biol Chem 286(27):23967-74. Epub 2011 May 16.
2011
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| 42 | ADAM10, ADAM9
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| ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.
|
| Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW.
|
| J Biol Chem 286(47):40443-51. doi: 10.1074/jbc.M111.280495. Epub 2011 Sep 28.
2011
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| 43 | ADAM10, ADAM19, ADAM28, ADAMTS6
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| Gene expression profile of ADAMs and ADAMTSs metalloproteinases in normal and malignant plasma cells and in the bone marrow environment.
|
| Bret C, Hose D, Reme T, Kassambara A, Seckinger A, Meissner T, Schved JF, Kanouni T, Goldschmidt H, Klein B.
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| Exp Hematol 39(5):546-557.e8. doi: 10.1016/j.exphem.2011.02.002. Epub 2011 Mar 3.
2011
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| 44 | ADAM10, MICA
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| Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide.
|
| Barsoum IB, Hamilton TK, Li X, Cotechini T, Miles EA, Siemens DR, Graham CH.
|
| Cancer Res 71(24):7433-41. doi: 10.1158/0008-5472.CAN-11-2104. Epub 2011 Oct 17. Erratum in: Cancer Res. 2012 Feb 1;72(3):827. 2011
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| 45 | ADAM10
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| Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis.
|
| Yoda M, Kimura T, Tohmonda T, Uchikawa S, Koba T, Takito J, Morioka H, Matsumoto M, Link DC, Chiba K, Okada Y, Toyama Y, Horiuchi K.
|
| Blood 118(26):6939-42. doi: 10.1182/blood-2011-06-357210. Epub 2011 Oct 31.
2011
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| 46 | ADAM10, FCER2
|
| CD23 Sheddase A disintegrin and metalloproteinase 10 (ADAM10) is also required for CD23 sorting into B cell-derived exosomes.
|
| Mathews JA, Gibb DR, Chen BH, Scherle P, Conrad DH.
|
| J Biol Chem 285(48):37531-41. Epub 2010 Sep 28. 2010
|
| 47 | ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
|
| Regional expression of the ADAMs in developing chicken cochlea.
|
| Yan X, Lin J, Wang H, Markus A, Wree A, Rolfs A, Luo J.
|
| Dev Dyn 239(8):2256-65.PMID: 20658692 2010
|
| 48 | ADAM10, ADAM17, ADAM22, ADAM23, ADAM9
|
| Expression of seven members of the ADAM family in developing chicken spinal cord.
|
| Lin J, Yan X, Markus A, Redies C, Rolfs A, Luo J.
|
| Dev Dyn 239(4):1246-54.PMID: 20235233 2010
|
| 49 | ADAM10
|
| ADAM10 is the physiologically relevant, constitutive alpha-secretase of the amyloid precursor protein in primary neurons.
|
| Kuhn PH, Wang H, Dislich B, Colombo A, Zeitschel U, Ellwart JW, Kremmer E, Rossner S, Lichtenthaler SF.
|
| EMBO J 29(17):3020-32. Epub 2010 Jul 30.
2010
|
| 50 | ADAM10, ESR1
|
| EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.
|
| Fernandez JW, Rezai-Zadeh K, Obregon D, Tan J.
|
| FEBS Lett 584(19):4259-67. Epub 2010 Sep 17.
2010
|
| 51 | ADAM10, CDH2
|
| Synaptic localization and activity of ADAM10 regulate excitatory synapses through N-cadherin cleavage.
|
| Malinverno M, Carta M, Epis R, Marcello E, Verpelli C, Cattabeni F, Sala C, Mulle C, Di Luca M, Gardoni F.
|
| J Neurosci 30(48):16343-55.
2010
|
| 52 | ADAM10, GPNMB
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| ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.
|
| Rose AA, Annis MG, Dong Z, Pepin F, Hallett M, Park M, Siegel PM.
|
| PLoS One 5(8):e12093. doi: 10.1371/journal.pone.0012093.
2010
|
| 53 | ADAM10, ADAM15, ADAM9
|
| ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase.
|
| Tousseyn T, Thathiah A, Jorissen E, Raemaekers T, Konietzko U, Reiss K, Maes E, Snellinx A, Serneels L, Nyabi O, Annaert W, Saftig P, Hartmann D, De Strooper B.
|
| J Biol Chem 284(17):11738-47. Epub 2009 Feb 11.
2009
|
| 54 | ADAM10, ADAM17, NOTCH1
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| Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling.
|
| Bozkulak EC, Weinmaster G.
|
| Mol Cell Biol 29(21):5679-95. Epub 2009 Aug 24.
2009
|
| 55 | ADAM10, TSPAN12
|
| Tetraspanin12 regulates ADAM10-dependent cleavage of amyloid precursor protein.
|
| Xu D, Sharma C, Hemler ME.
|
| FASEB J 23(11):3674-81. Epub 2009 Jul 8.PMID: 19587294 2009
|
| 56 | ADAM10
|
| Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma.
|
| Kohga K, Takehara T, Tatsumi T, Miyagi T, Ishida H, Ohkawa K, Kanto T, Hiramatsu N, Hayashi N.
|
| Cancer Res 69(20):8050-7. Epub 2009 Oct 13.PMID: 19826051 2009
|
| 57 | ADAM10
|
| Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.
|
| Kim M, Suh J, Romano D, Truong MH, Mullin K, Hooli B, Norton D, Tesco G, Elliott K, Wagner SL, Moir RD, Becker KD, Tanzi RE.
|
| Hum Mol Genet 18(20):3987-96. Epub 2009 Jul 15.PMID: 19608551 2009
|
| 58 | ADAM10
|
| Human mesenchymal stem cells induce E-cadherin degradation in breast carcinoma spheroids by activating ADAM10.
|
| Dittmer A, Hohlfeld K, Lützkendorf J, Müller LP, Dittmer J.
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| Cell Mol Life Sci 66(18):3053-65. Epub 2009 Jul 15.PMID: 19603142 2009
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| 59 | ADAM10
|
| Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein.
|
| Taylor DR, Parkin ET, Cocklin SL, Ault JR, Ashcroft AE, Turner AJ, Hooper NM.
|
| J Biol Chem 284(34):22590-600. Epub 2009 Jun 29.PMID: 19564338 2009
|
| 60 | ADAM10
|
| Up-regulation of the alpha-secretase ADAM10 by retinoic acid receptors and acitretin.
|
| Tippmann F, Hundt J, Schneider A, Endres K, Fahrenholz F.
|
| FASEB J 23(6):1643-54. Epub 2009 Jan 14.PMID: 19144697 2009
|
| 61 | ADAM10, ADAM17, CXCL16
|
| The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells.
|
| Schramme A, Abdel-Bakky MS, Kämpfer-Kolb N, Pfeilschifter J, Gutwein P.
|
| Biochem Biophys Res Commun 370(2):311-6. Epub 2008 Mar 26.
2008
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| 62 | ADAM10
|
| The isolated N-terminal domains of TIMP-1 and TIMP-3 are insufficient for ADAM10 inhibition.
|
| Rapti M, Atkinson SJ, Lee MH, Trim A, Moss M, Murphy G.
|
| Biochem J 411(2):433-9.PMID: 18215140 2008
|
| 63 | ADAM10
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| Functional role of N-glycosylation from ADAM10 in processing, localization and activity of the enzyme.
|
| Escrevente C, Morais VA, Keller S, Soares CM, Altevogt P, Costa J.
|
| Biochim Biophys Acta 1780(6):905-13. Epub 2008 Mar 13.PMID: 18381078 2008
|
| 64 | ADAM10
|
| The metalloproteinase-disintegrin ADAM10 is exclusively expressed by type I muscle fibers.
|
| Dehmel T, Goebel HH, Hartung HP, Lehmann H, Wiendl H, Kieseier BC.
|
| Muscle Nerve 38(2):1049-51.
2008
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| 65 | ADAM10,FASLG
|
| ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.
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| Schulte M, Reiss K, Lettau M, Maretzky T, Ludwig A, Hartmann D, de Strooper B, Janssen O, Saftig P.
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| Cell Death Differ 14(5):1040-9. Epub 2007 Feb 9. 2007
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| 66 | RECK, ADAM10
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| RECK modulates Notch signaling during cortical neurogenesis by regulating ADAM10 activity.
|
| Muraguchi T, Takegami Y, Ohtsuka T, Kitajima S, Chandana EP, Omura A, Miki T, Takahashi R, Matsumoto N, Ludwig A, Noda M, Takahashi C.
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| Nat Neurosci 10(7):838-45. Epub 2007 Jun 10. 2007
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| 67 | KL, ADAM10, ADAM17
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| Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17.
|
| Chen CD, Podvin S, Gillespie E, Leeman SE, Abraham CR.
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| Proc Natl Acad Sci U S A 104(50):19796-801. Epub 2007 Dec 3. 2007
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| 68 | ADAM10, SPPL2A
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| The Fas ligand intracellular domain is released by ADAM10 and SPPL2a cleavage in T-cells.
|
| Kirkin V, Cahuzac N, Guardiola-Serrano F, Huault S, Lückerath K, Friedmann E, Novac N, Wels WS, Martoglio B, Hueber AO, Zörnig M.
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| Cell Death Differ 14(9):1678-87. Epub 2007 Jun 8. 2007
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| 69 | ADAM10, FASLG
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| ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.
|
| Schulte M, Reiss K, Lettau M, Maretzky T, Ludwig A, Hartmann D, de Strooper B, Janssen O, Saftig P.
|
| Cell Death Differ 14(5):1040-9. Epub 2007 Feb 9.
2007
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| 70 | ADAM10, ADAM17, FURIN
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| Furin is an endogenous regulator of alpha-secretase associated APP processing.
|
| Hwang EM, Kim SK, Sohn JH, Lee JY, Kim Y, Kim YS, Mook-Jung I.
|
| Biochem Biophys Res Commun 349(2):654-9. Epub 2006 Aug 22. 2006
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| 71 | CDH1, ADAM10
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| ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation.
|
| Maretzky T, Reiss K, Ludwig A, Buchholz J, Scholz F, Proksch E, de Strooper B, Hartmann D, Saftig P.
|
| Proc Natl Acad Sci U S A 102(26):9182-7. Epub 2005 Jun 15. 2005
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| 72 | BTC, ADAM10
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| ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.
|
| Sanderson MP, Erickson SN, Gough PJ, Garton KJ, Wille PT, Raines EW, Dunbar AJ, Dempsey PJ.
|
| J Biol Chem 280(3):1826-37. Epub 2004 Oct 26. 2005
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| 73 | ADAM10, CDH2
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| ADAM10 cleavage of N-cadherin and regulation of cell-cell adhesion and beta-catenin nuclear signalling.
|
| Reiss K, Maretzky T, Ludwig A, Tousseyn T, de Strooper B, Hartmann D, Saftig P.
|
| EMBO J 24(4):742-52. Epub 2005 Feb 3. Erratum in: EMBO J. 2005 May 4;24(9):1762. 2005
|
| 74 | ADAM10
|
| ADAM10-mediated cleavage of L1 adhesion molecule at the cell surface and in released membrane vesicles.
|
| Gutwein P, Mechtersheimer S, Riedle S, Stoeck A, Gast D, Joumaa S, Zentgraf H, Fogel M, Altevogt DP.
|
| FASEB J 17(2):292-4. Epub 2002 Dec 03. 2003
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| 75 | CX3CL1, ADAM10
|
| The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.
|
| Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A.
|
| Blood 102(4):1186-95. Epub 2003 Apr 24. 2003
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| 76 | ADAM10
|
| The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts.
|
| Hartmann D, de Strooper B, Serneels L, Craessaerts K, Herreman A, Annaert W, Umans L, Lubke T, Lena Illert A, von Figura K, Saftig P.
|
| Hum Mol Genet 11(21):2615-24. 2002
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| 77 | ADAM10
|
| [alpha]-Secretase ADAM10 as well as [alpha]APPs is reduced in platelets and CSF of Alzheimer disease patients.
|
| Colciaghi F, Borroni B, Pastorino L, Marcello E, Zimmermann M, Cattabeni F, Padovani A, Di Luca M.
|
| Mol Med 8(2):67-74. 2002
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| 78 | ADAM10, YWHAZ, MLF1
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| MADM, a novel adaptor protein that mediates phosphorylation of the 14-3-3 binding site of myeloid leukemia factor 1.
|
| Lim R, Winteringham LN, Williams JH, McCulloch RK, Ingley E, Tiao JY, Lalonde JP, Tsai S, Tilbrook PA, Sun Y, Wu X, Morris SW, Klinken SP.
|
| J Biol Chem 277(43):40997-1008. Epub 2002 Aug 09. 2002
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| 79 | ADAM10, ADAM17
|
| Metalloprotease-disintegrin (ADAM) genes are widely and differentially expressed in the adult CNS.
|
| Karkkainen I, Rybnikova E, Pelto-Huikko M, Huovila AP.
|
| Mol Cell Neurosci 15(6):547-60. 2000
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| 80 | ADAM10, APP
|
| Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease.
|
| Lammich S, et al.
|
| Proc Natl Acad Sci U S A 96(7):3922-7. 1999
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| 81 | ADAM10
|
| Localization of ADAM10 and Notch receptors in bone.
|
| Dallas DJ, et al.
|
| Bone 25(1):9-15 1999
|
| 82 | ADAM10
|
| Human metalloprotease-disintegrin Kuzbanian regulates sympathoadrenal cell fate in development and neoplasia.
|
| Yavari R, et al.
|
| Hum Mol Genet 7 : 1161-1167. 1998
|
| 83 | ADAM10
|
| Radiation hybrid mapping of human ADAM10 gene to chromosome 15.
|
| Yamazaki K, Mizui Y, Tanaka I.
|
| Genomics 45(2):457-9. 1997
|
| 84 | ADAM8, ADAM10, ADAM11
|
| ADAM, a novel family of membrane proteins containing A disintegrin and metalloprotease domain : multipotential functions in cell-cell and cell-matrix interactions.
|
| Wolfsberg TG, et al.
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| J Cell Biol 131 : 275-278. 1995
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