| 1 | ACSL4
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| Overexpression of Acyl-CoA Ligase 4 (ACSL4) in Patients with Hepatocellular Carcinoma and its Prognosis.
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| Sun XJ, Xu GL.
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| Med Sci Monit 23:4343-4350.
2017
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| 2 | ACSL4
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| ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
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| Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M.
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| Nat Chem Biol 13(1):91-98. doi: 10.1038/nchembio.2239. Epub 2016 Nov 14.
2017
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| 3 | ACSL3, ACSL4, ACSL5
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| Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.
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| Ansari IH, Longacre MJ, Stoker SW, Kendrick MA, O'Neill LM, Zitur LJ, Fernandez LA, Ntambi JM, MacDonald MJ.
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| Arch Biochem Biophys 618:32-43. doi: 10.1016/j.abb.2017.02.001. Epub 2017 Feb 11. 2017
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| 4 | ACSL4
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| Identification of ACSL4 as a biomarker and contributor of ferroptosis.
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| Yuan H, Li X, Zhang X, Kang R, Tang D.
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| Biochem Biophys Res Commun 478(3):1338-43. doi: 10.1016/j.bbrc.2016.08.124. Epub 2016 Aug 23.
2016
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| 5 | ACSL4, PPARD
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| PPARδ activation induces hepatic long-chain acyl-CoA synthetase 4 expression in vivo and in vitro.
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| Kan CF, Singh AB, Dong B, Shende VR, Liu J.
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| Biochim Biophys Acta 1851(5):577-87. doi: 10.1016/j.bbalip.2015.01.008. Epub 2015 Jan 31.
2015
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| 6 | ACSL4
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| Differentially localized acyl-CoA synthetase 4 isoenzymes mediate the metabolic channeling of fatty acids towards phosphatidylinositol.
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| Küch EM, Vellaramkalayil R, Zhang I, Lehnen D, Brügger B, Sreemmel W, Ehehalt R, Poppelreuther M, Füllekrug J.
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| Biochim Biophys Acta 1841(2):227-39.
2014
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| 7 | ACSL4
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| Long-chain acyl-CoA synthetase 4 is regulated by phosphorylation.
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| Smith ME, Saraceno GE, Capani F, Castilla R.
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| Biochem Biophys Res Commun 430(1):272-7. doi: 10.1016/j.bbrc.2012.10.138. Epub 2012 Nov 15.
2013
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| 8 | ACSL4
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| Characterization of the mouse promoter region of the acyl-CoA synthetase 4 gene: role of Sp1 and CREB.
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| Orlando U, Cooke M, Cornejo Maciel F, Papadopoulos V, Podestá EJ, Maloberti P.
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| Mol Cell Endocrinol 369(1-2):15-26. doi: 10.1016/j.mce.2013.01.016. Epub 2013 Jan 31.
2013
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| 9 | ACSL4
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| A novel role of brain-type ACS4 isotype in neuronal differentiation.
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| Cho YY.
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| Biochem Biophys Res Commun 419(3):505-10. doi: 10.1016/j.bbrc.2012.02.046. Epub 2012 Feb 15.
2012
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| 10 | ACSL4, PTPN11
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| Tyrosine phosphatase SHP2 regulates the expression of acyl-CoA synthetase ACSL4.
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| Cooke M, Orlando U, Maloberti P, Podesta EJ, Cornejo Maciel F.
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| J Lipid Res Lipid Res. 2011 Sep 8. [Epub ahead of print]
2011
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| 11 | ACSL4, MRX63, MRX68
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| X inactivation testing for identifying a non-syndromic X-linked mental retardation gene.
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| Yonath H, Marek-Yagel D, Resnik-Wolf H, Abu-Horvitz A, Baris HN, Shohat M, Frydman M, Pras E.
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| J Appl Genet Appl Genet. 2011 May 17. [Epub ahead of print]
2011
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| 12 | ACSL4, HTATIP2, RAB5A, SH3GLB1
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| A novel TIP30 protein complex regulates EGF receptor signaling and endocytic degradation.
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| Zhang C, Li A, Zhang X, Xiao H.
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| J Biol Chem 286(11):9373-81. Epub 2011 Jan 20.
2011
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| 13 | ACSL4, HTATIP2, RAB5A, SH3GLB1
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| The TIP30 protein complex, arachidonic acid and coenzyme a are required for vesicle membrane fusion.
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| Zhang C, Li A, Gao S, Zhang X, Xiao H.
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| PLoS One 6(6):e21233. Epub 2011 Jun 24.
2011
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| 14 | ACSL4
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| Long-chain acyl-CoA synthetase 4 modulates prostaglandin E₂ release from human arterial smooth muscle cells.
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| Golej DL, Askari B, Kramer F, Barnhart S, Vivekanandan-Giri A, Pennathur S, Bornfeldt KE.
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| J Lipid Res 52(4):782-93. Epub 2011 Jan 17.
2011
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| 15 | ACSL4, AMME, ATS1
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| Intellectual disability, midface hypoplasia, facial hypotonia, and Alport syndrome are associated with a deletion in Xq22.3.
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| Rodriguez JD, Bhat SS, Meloni I, Ladd S, Leslie ND, Doyne EO, Renieri A, Dupont BR, Stevenson RE, Schwartz CE, Srivastava AK.
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| Am J Med Genet A 152A(3):713-7.PMID: 20186809 2010
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| 16 | ACSL4
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| Functional interaction between acyl-CoA synthetase 4, lipooxygenases and cyclooxygenase-2 in the aggressive phenotype of breast cancer cells.
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| Maloberti PM, Duarte AB, Orlando UD, Pasqualini ME, Solano AR, López-Otín C, Podestá EJ.
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| PLoS One 5(11):e15540.
2010
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| 17 | ACSL4
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| Analyses of mental dysfunction-related ACSl4 in Drosophila reveal its requirement for Dpp/BMP production and visual wiring in the brain.
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| Zhang Y, Chen D, Wang Z.
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| Hum Mol Genet 18(20):3894-905. Epub 2009 Jul 19.
2009
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| 18 | ACSL4
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| The effect of fatty acid-CoA ligase 4 on the growth of hepatic cancer cells.
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| Hu C, Chen L, Jiang Y, Li Y, Wang S.
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| Cancer Biol Ther 7(1):131-4. Epub 2007 Oct 19.
2008
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| 19 | ACSL4
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| Regulation of cell growth by fatty acid-CoA ligase 4 in human hepatocellular carcinoma cells.
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| Sung YK, Park MK, Hong SH, Hwang SY, Kwack MH, Kim JC, Kim MK.
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| Exp Mol Med 39(4):477-82.
2007
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| 20 | ACSL4, MRX68, MRX63
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| Disruption of DMD and deletion of ACSL4 causing developmental delay, hypotonia, and multiple congenital anomalies.
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| Bhat SS, Schmidt KR, Ladd S, Kim KC, Schwartz CE, Simensen RJ, DuPont BR, Stevenson RE, Srivastava AK.
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| Cytogenet Genome Res 112(1-2):170-5. 2006
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| 21 | ACSL4, AFF2, AGTR2, ARHGEF6, ARX, ATRX, DLG3, ESMR, FTSJ1, GDI1, IL1RAPL1, KDM5C, MECP2, MRX68, MRX89, MRX90, MRXS31, NLGN3, NLGN4X, OPHN1, PQBP1, RPS6KA3, RTTM, SLC16A2, SLC6A8, SYN1, TSPAN7, ZNF41
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| X linked mental retardation: a clinical guide.
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| Raymond FL.
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| J Med Genet 43(3):193-200. Epub 2005 Aug 23. 2006
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| 22 | ACSL4
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| Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: roles of cyclic AMP and p38 mitogen-activated protein kinase.
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| Liang YC, Wu CH, Chu JS, Wang CK, Hung LF, Wang YJ, Ho YS, Chang JG, Lin SY.
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| World J Gastroenterol 11(17):2557-63. 2005
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| 23 | ACSL4
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| Two more genes involved in recental retardation in an ever x-panding repertoire of proteins and pathways.
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| Devon R.
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| Clin Genet 62(1):24-25. No abstract available. 2002
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| 24 | ACSL4
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| FACL4, encoding fatty acid-CoA ligase 4, is mutated in nonspecific X-linked mental retardation.
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| Meloni I, Muscettola M, Raynaud M, Longo I, Bruttini M, Moizard MP, Gomot M, Chelly J, des Portes V, Fryns JP, Ropers HH, Magi B, Bellan C, Volpi N, Yntema HG, Lewis SE, Schaffer JE, Renieri A.
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| Nat Genet 30(4):436-40. 2002
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| 25 | ACSL4
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| Abnormal uterus with polycysts, accumulation of uterine prostaglandins, and reduced fertility in mice heterozygous for acyl-CoA synthetase 4 deficiency.
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| Cho YY, Kang MJ, Sone H, Suzuki T, Abe M, Igarashi M, Tokunaga T, Ogawa S, Takei YA, Miyazawa T, Sasano H, Fujino T, Yamamoto TT.
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| Biochem Biophys Res Commun 284(4):993-7. 2001
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| 26 | ACSL4
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| Exon/intron organization and transcription units of the human acyl-CoA synthetase 4 gene.
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| Minekura H, Kang MJ, Inagaki Y, Cho YY, Suzuki H, Fujino T, Yamamoto TT.
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| Biochem Biophys Res Commun 286(1):80-6. 2001
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| 27 | ACSL4
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| Fatty acid CoA ligase 4 is up-regulated in colon adenocarcinoma.
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| Cao Y, Dave KB, Doan TP, Prescott SM.
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| Cancer Res 61(23):8429-34. 2001
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| 28 | ACSL4
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| FACL4, a new gene encoding long-chain acyl-CoA synthetase 4, is deleted in a family with Alport syndrome, elliptocytosis, and mental retardation.
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| Piccini M, Vitelli F, Bruttini M, Pober BR, Jonsson JJ, Villanova M, Zollo M, Borsani G, Ballabio A, Renieri A.
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| Genomics 47(3):350-8. 1998
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| 29 | ACSL4
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| Cloning, expression, and chromosomal localization of human long-chain fatty acid-CoA ligase 4 (FACL4).
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| Cao Y, et al.
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| Genomics 49 : 327-330. 1998
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| 30 | ACSL1, ACSL3, ACSL4
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| Mutational analysis of a fatty acyl-coenzyme A synthetase signature motif identifies seven amino acid residues that modulate fatty acid substrate specificity.
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| Black PN, et al.
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| J Biol Chem 272 : 4896-4903. 1997
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