| 1 | ACR, SPGF87
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| ACROSIN deficiency causes total fertilization failure in humans by preventing the sperm from penetrating the zona pellucida.
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| Hua R, Xue R, Liu Y, Li Y, Sha X, Li K, Gao Y, Shen Q, Lv M, Xu Y, Zhang Z, He X, Cao Y, Wu H.
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| Hum Reprod. Jun 1;38(6):1213-1223. doi: 10.1093/humrep/dead059. 2023
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| 2 | ACR
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| Low acrosin activity is associated with decreased Spam1/acrosin expression and GSH deficiency-caused premature acrosome release of human sperm cells.
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| Lin M, Ling P, He Q, Chen D, Zheng L, Tang L, Jiang SW.
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| Cell Tissue Res. Dec;394(3):529-545. doi: 10.1007/s00441-023-03826-x. Epub 2023 Oct 14. 2023
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| 3 | ACR
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| Mitochondrial functionality modifies human sperm acrosin activity, acrosome reaction capability and chromatin integrity.
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| Zhang G, Yang W, Zou P, Jiang F, Zeng Y, Chen Q, Sun L, Yang H, Zhou N, Wang X, Liu J, Cao J, Zhou Z, Ao L.
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| Hum Reprod. Jan 1;34(1):3-11. doi: 10.1093/humrep/dey335. 2019
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| 4 | ACR
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| A delayed sperm penetration of cumulus layers by disruption of acrosin gene in rats.
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| Isotani A, Matsumura T, Ogawa M, Tanaka T, Yamagata K, Ikawa M, Okabe M.
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| Biol Reprod. Jul 1;97(1):61-68. doi: 10.1093/biolre/iox066. 2017
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| 5 | ACR
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| Design and synthesis of phenylisoxazole derivatives as novel human acrosin inhibitors. 2014 PMID: .
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| Zhao J, Tian W, Qi J, Lv D, Liu Y, Jiang Y, Dong G, Chen Q, Zhou Y, Zhu J, Wang H, Sheng C, Lv J.
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| Bioorg Med Chem Lett. Jul 1;24(13):2802-6. doi: 10.1016/j.bmcl.2014.04.118. Epub 2014 May 9. 2014
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| 6 | ACR
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| Modes of acrosin functioning during fertilization.
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| Mao HT, Yang WX.
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| Gene. Sep 10;526(2):75-9. doi: 10.1016/j.gene.2013.05.058. Epub 2013 Jun 4. 2013
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| 7 | ACR, MMP2
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| MMP2 and acrosin are major proteinases associated with the inner acrosomal membrane and may cooperate in sperm penetration of the zona pellucida during fertilization
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| Ferrer M, Rodriguez H, Zara L, Yu Y, Xu W, Oko R.
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| Cell Tissue Res. Sep;349(3):881-95. doi: 10.1007/s00441-012-1429-1. Epub 2012 May 22. 2012
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| 8 | ACR
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| The proacrosin binding protein, sp32, is tyrosine phosphorylated during capacitation of pig sperm.
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| DubŽ C, Leclerc P, Baba T, Reyes-Moreno C, Bailey JL.
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| J Androl 26(4):519-28. 2005
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| 9 | ACR
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| Biochemical and molecular studies of the proacrosin/acrosin system in patients with unexplained infertility.
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| Mar’ SI, Rawe V, Biancotti JC, Charreau EH, Dain L, Vazquez-Levin MH.
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| Fertil Steril 79 Suppl 3:1676-9. No abstract available. 2003
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| 10 | ACR
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| Role of acrosomal matrix proteases in sperm-zona pellucida interactions.
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| Honda A, Siruntawineti J, Baba T.
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| Hum Reprod Update 8(5):405-12. Review. 2002
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| 11 | ACR, MTM1, SETDB1
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| Assignment of a novel bifurcated SET domain gene, SETDB1, to human chromosome band 1q21 by in situ hybridization and radiation hybrids.
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| Harte PJ, Wu W, Carrasquillo MM, Matera AG.
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| Cytogenet Cell Genet 84(1-2):83-6. 1999
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| 12 | ACR, COL3A1, EDS4A, FAN
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| COL3A1 mutations cause variable clinical phenotypes including acrogeria and vascular rupture.
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| Pope FM, et al.
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| Br J Dermatol 135 : 163-181. 1996
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| 13 | ACR
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| Mapping of the proacrosin locus in mouse and humans.
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| Bucan M, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 2045. 1991
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| 14 | ACR
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| Molecular cloning of preproacrosin and analysis of its expression pattern in spermatogenesis.
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| Adham IM, Klemm U, Maier WM, Hoyer-Fender S, Tsaousidou S, Engel W.
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| Eur J Biochem 182(3):563-8. 1989
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| 15 | ACR
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| The gene encoding the human preproacrosin (ACR) maps to the q13-qter region on chromosome 22.
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| Adham IM, et al.
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| Hum Genet 84 : 59-62. 1989
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