Citations for
1ACKR3, ARX, LHX6
Lhx6 directly regulates Arx and CXCR7 to determine cortical interneuron fate and laminar position.
Vogt D, Hunt RF, Mandal S, Sandberg M, Silberberg SN, Nagasawa T, Yang Z, Baraban SC, Rubenstein JL.
Neuron 82(2):350-64. doi: 10.1016/j.neuron.2014.02.030. 2014
2ACKR3, CXCL12, CXCR4
CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.
Abe P, Mueller W, Schütz D, MacKay F, Thelen M, Zhang P, Stumm R.
Development 141(9):1857-63. doi: 10.1242/dev.104224. Epub 2014 Apr 9. 2014
3ACKR3, CXCR4
Chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 regulate vascular α₁-adrenergic receptor function.
Bach HH 4th, Wong YM, Tripathi A, Nevins AM, Gamelli RL, Volkman BF, Byron KL, Majetschak M.
Mol Med 20:435-47. doi: 10.2119/molmed.2014.00101. 2014
4ACKR3
Targeting CXCR7/ACKR3 as a therapeutic strategy to promote remyelination in the adult central nervous system.
Williams JL, Patel JR, Daniels BP, Klein RS.
J Exp Med 211(5):791-9. doi: 10.1084/jem.20131224. Epub 2014 Apr 14. 2014
5ACKR3, CXCR4
CXCR7 is highly expressed in acute lymphoblastic leukemia and potentiates CXCR4 response to CXCL12.
Melo Rde C, Longhini AL, Bigarella CL, Baratti MO, Traina F, Favaro P, de Melo Campos P, Saad ST.
PLoS One 9(1):e85926. doi: 10.1371/journal.pone.0085926. eCollection 2014. 2014
6ACKR3
CXCR7 influences the migration of B cells during maturation.
Humpert ML, Pinto D, Jarrossay D, Thelen M.
Eur J Immunol 44(3):694-705. doi: 10.1002/eji.201343907. Epub 2014 Feb 19. 2014
7ACKR3, CXCL2
Estrogen represses CXCR7 gene expression by inhibiting the recruitment of NFκB transcription factor at the CXCR7 promoter in breast cancer cells.
Kerdivel G, Boudot A, Pakdel F.
Biochem Biophys Res Commun 431(4):729-33. doi: 10.1016/j.bbrc.2013.01.050. Epub 2013 Jan 23. 2013
8ACKR3, CXCL12
CXCR7 silencing attenuates cell adaptive response to stromal cell derived factor 1α after hypoxia.
Liu S, Jia X, Li C, Han X, Yan W, Xing Y.
PLoS One 8(1):e55290. doi: 10.1371/journal.pone.0055290. Epub 2013 Jan 31. 2013
9ACKR3, CXCL12
CXCR7 mediates SDF1-induced melanocyte migration.
Lee E, Han J, Kim K, Choi H, Cho EG, Lee TR.
Pigment Cell Melanoma Res 26(1):58-66. doi: 10.1111/pcmr.12024. Epub 2012 Oct 26. 2013
10ACKR3, ADRBK1
Grk2 is an essential regulator of CXCR7 signalling in astrocytes.
Lipfert J, Ödemis V, Engele J.
Cell Mol Neurobiol 33(1):111-8. doi: 10.1007/s10571-012-9876-5. Epub 2012 Sep 2. 2013
11ACKR3, CXCL12
Rapid uptake and degradation of CXCL12 depend on CXCR7 carboxyl-terminal serine/threonine residues.
Hoffmann F, Müller W, Schütz D, Penfold ME, Wong YH, Schulz S, Stumm R.
J Biol Chem 287(34):28362-77. doi: 10.1074/jbc.M111.335679. Epub 2012 Jun 26. 2012
12ACKR3
Ubiquitination of CXCR7 controls receptor trafficking.
Canals M, Scholten DJ, de Munnik S, Han MK, Smit MJ, Leurs R.
PLoS One 7(3):e34192. doi: 10.1371/journal.pone.0034192. Epub 2012 Mar 23. 2012
13ACKR3
Carboxy-terminus of CXCR7 regulates receptor localization and function.
Ray P, Mihalko LA, Coggins NL, Moudgil P, Ehrlich A, Luker KE, Luker GD.
Int J Biochem Cell Biol 44(4):669-78. doi: 10.1016/j.biocel.2012.01.007. Epub 2012 Jan 25. 2012
14ACKR3, CXCL12
Chemokine receptor CXCR7 mediates human endothelial progenitor cells survival, angiogenesis, but not proliferation.
Yan X, Cai S, Xiong X, Sun W, Dai X, Chen S, Ye Q, Song Z, Jiang Q, Xu Z.
J Cell Biochem 113(4):1437-46. doi: 10.1002/jcb.24015. 2012
15ACKR3, CXCL12, CXCR4
The role of CXCR7 on the adhesion, proliferation and angiogenesis of endothelial progenitor cells.
Dai X, Tan Y, Cai S, Xiong X, Wang L, Ye Q, Yan X, Ma K, Cai L.
J Cell Mol Med 15(6):1299-309. doi: 10.1111/j.1582-4934.2011.01301.x. 2011
16ACKR3
The chemokine receptor CXCR7 functions to regulate cardiac valve remodeling.
Yu S, Crawford D, Tsuchihashi T, Behrens TW, Srivastava D.
Dev Dyn 240(2):384-93. doi: 10.1002/dvdy.22549. 2011
17ACKR3
CXCR7 protein is not expressed on human or mouse leukocytes.
Berahovich RD, Zabel BA, Penfold ME, Lewén S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ.
J Immunol 185(9):5130-9. doi: 10.4049/jimmunol.1001660. Epub 2010 Oct 1. 2010
18ACKR3, CXCL11, CXCL12
CXCR7 functions as a scavenger for CXCL12 and CXCL11.
Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, Rot A, Thelen M.
PLoS One 5(2):e9175. doi: 10.1371/journal.pone.0009175. 2010
19ACKR3, HIC1
Scavenger Chemokine (CXC Motif) Receptor 7 (CXCR7) Is a Direct Target Gene of HIC1 (Hypermethylated in Cancer 1).
Van Rechem C, Rood BR, Touka M, Pinte S, Jenal M, Guérardel C, Ramsey K, Monté D, Bégue A, Tschan MP, Stephan DA, Leprince D.
J Biol Chem 284(31):20927-35. Epub 2009 Jun 12. 2009
20ACKR3
Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer.
Iwakiri S, Mino N, Takahashi T, Sonobe M, Nagai S, Okubo K, Wada H, Date H, Miyahara R.
Cancer 115(11):2580-93. 2009
21ACKR3
Differential expression of RDC1/CXCR7 in the human placenta.
Tripathi V, Verma R, Dinda A, Malhotra N, Kaur J, Luthra K.
J Clin Immunol 29(3):379-86. Epub 2008 Oct 28. 2009
22ACKR3
A crosstalk between intracellular CXCR7 and CXCR4 involved in rapid CXCL12-triggered integrin activation but not in chemokine-triggered motility of human T lymphocytes and CD34+ cells.
Hartmann TN, Grabovsky V, Pasvolsky R, Shulman Z, Buss EC, Spiegel A, Nagler A, Lapidot T, Thelen M, Alon R.
J Leukoc Biol 84(4):1130-40. Epub 2008 Jul 24. 2008
23ACKR3
The role of CXCR7/RDC1 as a chemokine receptor for CXCL12/SDF-1 in prostate cancer.
Wang J, Shiozawa Y, Wang J, Wang Y, Jung Y, Pienta KJ, Mehra R, Loberg R, Taichman RS.
J Biol Chem 283(7):4283-94. Epub 2007 Dec 5. 2008
24ACKR3
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature.
Miao Z, Luker KE, Summers BC, Berahovich R, Bhojani MS, Rehemtulla A, Kleer CG, Essner JJ, Nasevicius A, Luker GD, Howard MC, Schall TJ.
Proc Natl Acad Sci U S A 104(40):15735-40. Epub 2007 Sep 26. 2007
25ACKR3
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.
Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, Wei K, McMaster BE, Wright K, Howard MC, Schall TJ.
J Exp Med 203(9):2201-13. Epub 2006 Aug 28. 2006
26ACKR3
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development.
Burns JM, Summers BC, Wang Y, Melikian A, Berahovich R, Miao Z, Penfold ME, Sunshine MJ, Littman DR, Kuo CJ, Wei K, McMaster BE, Wright K, Howard MC, Schall TJ.
J Exp Med 203(9):2201-13. Epub 2006 Aug 28. 2006
27ACKR3, CXCL12
The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes.
Balabanian K, Lagane B, Infantino S, Chow KY, Harriague J, Moepps B, Arenzana-Seisdedos F, Thelen M, Bachelerie F.
J Biol Chem 280(42):35760-6. Epub 2005 Aug 17. 2005
28ACKR3, HMGA2
Fusion of RDC1 with HMGA2 in lipomas as the result of chromosome aberrations involving 2q35-37 and 12q13-15.
Broberg K, Zhang M, Strombeck B, Isaksson M, Nilsson M, Mertens F, Mandahl N, Panagopoulos I.
Int J Oncol 21(2):321-6. 2002