| 1 | ACER2
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| Alkaline ceramidase 2 is essential for the homeostasis of plasma sphingoid bases and their phosphates.
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| Li F, Xu R, Low BE, Lin CL, Garcia-Barros M, Schrandt J, Mileva I, Snider A, Luo CK, Jiang XC, Li MS, Hannun YA, Obeid LM, Wiles MV, Mao C.
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| FASEB J 32(6):3058-3069. doi: 10.1096/fj.201700445RR. Epub 2018 Jan 22.
2018
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| 2 | ACER1, ACER2, ACER3, ASAH1, ASAH2B
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| Ceramidases, roles in sphingolipid metabolism and in health and disease.
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| Coant N, Sakamoto W, Mao C, Hannun YA.
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| Adv Biol Regul 63:122-131. doi: 10.1016/j.jbior.2016.10.002. Epub 2016 Oct 11. Review.
2017
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| 3 | ACER2
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| Alkaline ceramidase 2 and its bioactive product sphingosine are novel regulators of the DNA damage response.
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| Xu R, Wang K, Mileva I, Hannun YA, Obeid LM, Mao C.
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| Oncotarget 7(14):18440-57. doi: 10.18632/oncotarget.7825.
2016
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| 4 | ACER2, ACER3
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| Alkaline ceramidase 3 (ACER3) hydrolyzes unsaturated long-chain ceramides, and its down-regulation inhibits both cell proliferation and apoptosis.
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| Hu W, Xu R, Sun W, Szulc ZM, Bielawski J, Obeid LM, Mao C.
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| J Biol Chem 285(11):7964-76. Epub 2010 Jan 12.PMID: 20068046 2010
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| 5 | ACER1, ACER2, ACER3
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| Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.
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| Xu R, Sun W, Jin J, Obeid LM, Mao C.
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| FASEB J 24(7):2507-15. doi: 10.1096/fj.09-153635. Epub 2010 Mar 5.
2010
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| 6 | ACER2
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| Substrate specificity, membrane topology, and activity regulation of human alkaline ceramidase 2 (ACER2).
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| Sun W, Jin J, Xu R, Hu W, Szulc ZM, Bielawski J, Obeid LM, Mao C.
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| J Biol Chem 285(12):8995-9007. doi: 10.1074/jbc.M109.069203. Epub 2010 Jan 20.
2010
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| 7 | ACER2
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| Alkaline ceramidase 2 regulates beta1 integrin maturation and cell adhesion.
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| Sun W, Hu W, Xu R, Jin J, Szulc ZM, Zhang G, Galadari SH, Obeid LM, Mao C.
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| FASEB J 23(2):656-66. doi: 10.1096/fj.08-115634. Epub 2008 Oct 22.
2009
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| 8 | ACER1, ACER2, ACER3
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| Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate.
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| Mao C, Obeid LM.
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| Biochim Biophys Acta 1781(9):424-34. Epub 2008 Jun 13. Review.PMID: 18619555 2008
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| 9 | ACER1, ACER2, ACER3, ASAH1
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| Kinetic characteristics of acidic and alkaline ceramidase in human epidermis.
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| Houben E, Uchida Y, Nieuwenhuizen WF, De Paepe K, Vanhaecke T, Holleran WM, Rogiers V.
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| Skin Pharmacol Physiol 20(4):187-94. Epub 2007 Mar 29.
2007
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| 10 | ACER2
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| Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P.
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| Xu R, Jin J, Hu W, Sun W, Bielawski J, Szulc Z, Taha T, Obeid LM, Mao C.
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| FASEB J 20(11):1813-25. 2006
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