1 | ACER1, ACER2, ACER3, ASAH1, ASAH2B
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| Ceramidases, roles in sphingolipid metabolism and in health and disease.
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| Coant N, Sakamoto W, Mao C, Hannun YA.
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| Adv Biol Regul 63:122-131. doi: 10.1016/j.jbior.2016.10.002. Epub 2016 Oct 11. Review.
2017
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2 | ACER1
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| Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure.
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| Liakath-Ali K, Vancollie VE, Lelliott CJ, Speak AO, Lafont D, Protheroe HJ, Ingvorsen C, Galli A, Green A, Gleeson D, Ryder E, Glover L, Vizcay-Barrena G, Karp NA, Arends MJ, Brenn T, Spiegel S, Adams DJ, Watt FM, van der Weyden L.
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| J Pathol 239(3):374-83. doi: 10.1002/path.4737. Epub 2016 May 30.
2016
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3 | ACER1, ACER2, ACER3
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| Role of alkaline ceramidases in the generation of sphingosine and its phosphate in erythrocytes.
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| Xu R, Sun W, Jin J, Obeid LM, Mao C.
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| FASEB J 24(7):2507-15. doi: 10.1096/fj.09-153635. Epub 2010 Mar 5.
2010
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4 | ACER1, ACER2, ACER3
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| Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate.
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| Mao C, Obeid LM.
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| Biochim Biophys Acta 1781(9):424-34. Epub 2008 Jun 13. Review.PMID: 18619555 2008
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5 | ACER1, ASAH1
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| Upregulation of the human alkaline ceramidase 1 and acid ceramidase mediates calcium-induced differentiation of epidermal keratinocytes.
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| Sun W, Xu R, Hu W, Jin J, Crellin HA, Bielawski J, Szulc ZM, Thiers BH, Obeid LM, Mao C.
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| J Invest Dermatol 128(2):389-97. Epub 2007 Aug 23.
2008
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6 | ACER1, ACER2, ACER3, ASAH1
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| Kinetic characteristics of acidic and alkaline ceramidase in human epidermis.
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| Houben E, Uchida Y, Nieuwenhuizen WF, De Paepe K, Vanhaecke T, Holleran WM, Rogiers V.
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| Skin Pharmacol Physiol 20(4):187-94. Epub 2007 Mar 29.
2007
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7 | ACER1
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| Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides.
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| Mao C, Xu R, Szulc ZM, Bielawski J, Becker KP, Bielawska A, Galadari SH, Hu W, Obeid LM.
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| J Biol Chem 278(33):31184-91. Epub 2003 Jun 3.
2003
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