Citations for
1ABL1, ERRFI1
Nuclear Gene 33/Mig6 regulates the DNA damage response through an ATM serine/threonine kinase-dependent mechanism.
Li C, Park S, Zhang X, Eisenberg LM, Zhao H, Darzynkiewicz Z, Xu D.
J Biol Chem 292(40):16746-16759. doi: 10.1074/jbc.M117.803338. Epub 2017 Aug 25. 2017
2ABL1, SMAD3, SNW1
Enhancement of TGF-β-induced Smad3 activity by c-Abl-mediated tyrosine phosphorylation of its coactivator SKI-interacting protein (SKIP).
Kuki K, Yamaguchi N, Iwasawa S, Takakura Y, Aoyama K, Yuki R, Nakayama Y, Kuga T, Hashimoto Y, Tomonaga T, Yamaguchi N.
Biochem Biophys Res Commun 490(3):1045-1051. doi: 10.1016/j.bbrc.2017.06.163. Epub 2017 Jun 28. 2017
3ABL1, HIPK2, PML
The Tyrosine Kinase c-Abl Promotes Homeodomain-interacting Protein Kinase 2 (HIPK2) Accumulation and Activation in Response to DNA Damage.
Reuven N, Adler J, Porat Z, Polonio-Vallon T, Hofmann TG, Shaul Y.
J Biol Chem 290(27):16478-88. doi: 10.1074/jbc.M114.628982. Epub 2015 May 5. 2015
4ABL1, CTTN
Role of c-Abl tyrosine kinase in smooth muscle cell migration.
Cleary RA, Wang R, Waqar O, Singer HA, Tang DD.
Am J Physiol Cell Physiol 306(8):C753-61. doi: 10.1152/ajpcell.00327.2013. Epub 2014 Jan 29. 2014
5ABL1, SNX2
Poor responses to tyrosine kinase inhibitors in a child with precursor B-cell acute lymphoblastic leukemia with SNX2-ABL1 chimeric transcript.
Masuzawa A, Kiyotani C, Osumi T, Shioda Y, Iijima K, Tomita O, Nakabayashi K, Oboki K, Yasuda K, Sakamoto H, Ichikawa H, Hata K, Yoshida T, Matsumoto K, Kiyokawa N, Mori T.
Eur J Haematol 92(3):263-7. doi: 10.1111/ejh.12234. Epub 2013 Nov 28. 2014
6ABL1, CLASP2
Abelson phosphorylation of CLASP2 modulates its association with microtubules and actin.
Engel U, Zhan Y, Long JB, Boyle SN, Ballif BA, Dorey K, Gygi SP, Koleske AJ, Vanvactor D.
Cytoskeleton (Hoboken) 71(3):195-209. doi: 10.1002/cm.21164. Epub 2014 Mar 12. 2014
7ABL1, ETV6
Variant of ETV6/ABL1 gene is associated with leukemia phenotype.
Park J, Kim M, Lim J, Kim Y, Han K, Kim JS, Lee S, Kim HJ, Min WS.
Acta Haematol 129(2):78-82. doi: 10.1159/000342490. Epub 2012 Nov 16. 2013
8ABL1, KAT5
KAT5 tyrosine phosphorylation couples chromatin sensing to ATM signalling.
Kaidi A, Jackson SP.
Nature 498(7452):70-4. doi: 10.1038/nature12201. Epub 2013 May 26. 2013
9ABL1, NOX5
NOX5 in human spermatozoa: expression, function, and regulation.
Musset B, Clark RA, DeCoursey TE, Petheo GL, Geiszt M, Chen Y, Cornell JE, Eddy CA, Brzyski RG, El Jamali A.
J Biol Chem 287(12):9376-88. doi: 10.1074/jbc.M111.314955. Epub 2012 Jan 30. 2012
10ABL1, STK3, STK4
Regulation of neuronal cell death by c-Abl-Hippo/MST2 signaling pathway.
Liu W, Wu J, Xiao L, Bai Y, Qu A, Zheng Z, Yuan Z.
PLoS One 7(5):e36562. doi: 10.1371/journal.pone.0036562. Epub 2012 May 9. 2012
11ABL1
A positive role for c-Abl in Atm and Atr activation in DNA damage response.
Wang X, Zeng L, Wang J, Chau JF, Lai KP, Jia D, Poonepalli A, Hande MP, Liu H, He G, He L, Li B.
Cell Death Differ. 18(1):5-15. 2011
12ABL1, BCR, MTOR
BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription.
Sheng Z, Ma L, Sun JE, Zhu LJ, Green MR.
Blood 118(10):2840-8. doi: 10.1182/blood-2010-12-322537. Epub 2011 Jun 29. 2011
13ABL1, CHEK2, EWSR1, MAP4K2
The Ewing sarcoma protein regulates DNA damage-induced alternative splicing.
Paronetto MP, Miñana B, Valcárcel J.
Mol Cell 43(3):353-68. doi: 10.1016/j.molcel.2011.05.035. 2011
14ABL1, FOXP1, SNX2
Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.
Ernst T, Score J, Deininger M, Hidalgo-Curtis C, Lackie P, Ershler WB, Goldman JM, Cross NC, Grand F.
Br J Haematol 153(1):43-6. doi: 10.1111/j.1365-2141.2010.08457.x. Epub 2011 Feb 1. 2011
15ABL1, EML1
ABL1 fusion genes in hematological malignancies: a review.
De Braekeleer E, Douet-Guilbert N, Rowe D, Bown N, Morel F, Berthou C, Férec C, De Braekeleer M.
Eur J Haematol. May;86(5):361-71. doi: 10.1111/j.1600-0609.2011.01586.x. Epub 2011 Mar 23. 2011
16ABL1, MAVS
c-Abl tyrosine kinase interacts with MAVS and regulates innate immune response.
Song T, Wei C, Zheng Z, Xu Y, Cheng X, Yuan Y, Guan K, Zhang Y, Ma Q, Shi W, Zhong H.
FEBS Lett 584(1):33-8. Epub .PMID: 19914245 2010
17ABL1
ABL1 rearrangements in T-cell acute lymphoblastic leukemia.
Hagemeijer A, Graux C.
Genes Chromosomes Cancer 49(4):299-308.PMID: 20073070 2010
18ABL1, AIMP2, FBP1, PRKN
Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function.
Ko HS, Lee Y, Shin JH, Karuppagounder SS, Gadad BS, Koleske AJ, Pletnikova O, Troncoso JC, Dawson VL, Dawson TM.
Proc Natl Acad Sci U S A 107(38):16691-6. Epub 2010 Sep 7. 2010
19ABL1, PITX1
The c-Abl tyrosine kinase stabilizes Pitx1 in the apoptotic response to DNA damage.
Yamaguchi T, Miki Y, Yoshida K.
Apoptosis 15(8):927-35. 2010
20ABL1
c-Abl kinase is required for beta 2 integrin-mediated neutrophil adhesion.
Cui L, Chen C, Xu T, Zhang J, Shang X, Luo J, Chen L, Ba X, Zeng X.
J Immunol 182(5):3233-42. 2009
21ABL1, BRCA2, RAD51
c-ABL tyrosine kinase stabilizes RAD51 chromatin association.
Shimizu H, Popova M, Fleury F, Kobayashi M, Hayashi N, Sakane I, Kurumizaka H, Venkitaraman AR, Takahashi M, Yamamoto K.
Biochem Biophys Res Commun 382(2):286-91. Epub 2009 Mar 11. 2009
22ABL1, CDON
Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation.
Bae GU, Kim BG, Lee HJ, Oh JE, Lee SJ, Zhang W, Krauss RS, Kang JS.
Mol Cell Biol 29(15):4130-43. Epub 2009 May 26. 2009
23ABL1, MSH5, TP73
Evidence for a direct involvement of hMSH5 in promoting ionizing radiation induced apoptosis
Tompkins JD, Wu X, Chu YL, Her C.
Exp Cell Res. Aug 15;315(14):2420-32. doi: 10.1016/j.yexcr.2009.05.004. Epub 2009 May 12. 2009
24DYRK2, ABL1, PRKCD, PRKDC
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage.
Yoshida K.
Trends Mol Med 14(7):305-13. Epub 2008 Jun 6. 2008
25ABL1, BCR
Deletions adjacent to BCR and ABL1 breakpoints occur in a substantial minority of chronic myeloid leukemia patients with masked Philadelphia rearrangements.
De Melo VA, Milojkovic D, Marin D, Apperley JF, Nacheva EP, Reid AG.
Cancer Genet Cytogenet 182(2):111-5. 2008
26ABL1, CPSF6, FGFR1, SFPQ
The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.
Hidalgo-Curtis C, Chase A, Drachenberg M, Roberts MW, Finkelstein JZ, Mould S, Oscier D, Cross NC, Grand FH.
Genes Chromosomes Cancer 47(5):379-85.PMID: 18205209 2008
27ABL1
Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
Oh AS, Lahusen JT, Chien CD, Fereshteh MP, Zhang X, Dakshanamurthy S, Xu J, Kagan BL, Wellstein A, Riegel AT.
Mol Cell Biol. 28(21):6580-93. 2008
28ABL1, ZMIZ1
Fusion of ZMIZ1 to ABL1 in a B-cell acute lymphoblastic leukaemia with a t(9;10)(q34;q22.3) translocation.
Soler G, Radford-Weiss I, Ben-Abdelali R, Mahlaoui N, Ponceau JF, Macintyre EA, Vekemans M, Bernard OA, Romana SP.
Leukemia 22(6):1278-80. Epub 2007 Nov 15. No abstract available. 2008
29WASF3, ABL1
c-Abl-mediated Phosphorylation of WAVE3 Is Required for Lamellipodia Formation and Cell Migration.
Sossey-Alaoui K, Li X, Cowell JK.
J Biol Chem 282(36):26257-65. Epub 2007 Jul 9. 2007
30ERCC6, ABL1
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase.
Imam SZ, Indig FE, Cheng WH, Saxena SP, Stevnsner T, Kufe D, Bohr VA.
Nucleic Acids Res 35(15):4941-51. Epub 2007 Jul 11. 2007
31ABL1, FGFR1OP, WRNIP1
Fibroblast growth factor receptor 1 oncogene partner as a novel prognostic biomarker and therapeutic target for lung cancer.
Mano Y, Takahashi K, Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Tsuchiya E, Nakamura Y, Daigo Y.
Cancer Sci 98(12):1902-13. Epub 2007 Sep 18. 2007
32ABL1
Characterization of ABL1 expression in adult T-cell acute lymphoblastic leukemia by oligonucleotide array analysis.
Chiaretti S, Tavolaro S, Ghia EM, Ariola C, Matteucci C, Elia L, Maggio R, Messina M, Ricciardi MR, Vitale A, Ritz J, Mecucci C, Guarini A, Foà R.
Haematologica 92(5):619-26. 2007
33ABL1,
Nuclear accumulations of p53 and Mdm2 are accompanied by reductions in c-Abl and p300 in zinc-depleted human hepatoblastoma cells.
Alshatwi AA, Han CT, Schoene NW, Lei KY.
Exp Biol Med (Maywood) 231(5):611-8. 2006
34ABL1,
Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.
Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.
J Biol Chem 281(11):7049-59. Epub 2006 Jan 12. 2006
35RB1, BCR, ABL1
Rb plays a role in survival of Abl-dependent human tumor cells as a downstream effector of Abl tyrosine kinase.
Nagano K, Itagaki C, Izumi T, Nunomura K, Soda Y, Tani K, Takahashi N, Takenawa T, Isobe T.
Oncogene 25(4):493-502. 2006
36ABL1
MUC1 oncoprotein blocks nuclear targeting of c-Abl in the apoptotic response to DNA damage.
Raina D, Ahmad R, Kumar S, Ren J, Yoshida K, Kharbanda S, Kufe D.
EMBO J. 25(16):3774-83. 2006
37ABL1
Abl kinase interacts with and phosphorylates vinexin.
Mitsushima M, Takahashi H, Shishido T, Ueda K, Kioka N.
FEBS Lett. 580(17):4288-95. 2006
38ABL1,
c-Abl regulates early growth response protein (EGR1) in response to oxidative stress.
Stuart JR, Kawai H, Tsai KK, Chuang EY, Yuan ZM.
Oncogene 24(55):8085-92. 2005
39ABL1, ABI1, WASF2
Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation.
Leng Y, Zhang J, Badour K, Arpaia E, Freeman S, Cheung P, Siu M, Siminovitch K.
Proc Natl Acad Sci U S A 102(4):1098-103. Epub 2005 Jan 18. 2005
40NUP214, ABL1, EML1
Fusion of EML1 to ABL1 in T-cell acute lymphoblastic leukemia with cryptic t(9;14)(q34;q32).
De Keersmaecker K, Graux C, Odero MD, Mentens N, Somers R, Maertens J, Wlodarska I, Vandenberghe P, Hagemeijer A, Marynen P, Cools J.
Blood 105(12):4849-52. Epub 2005 Feb 15. 2005
41TOPBP1, ABL1
Identification of TopBP1 as a c-Abl-interacting protein and a repressor for c-Abl expression.
Zeng L, Hu Y, Li B.
J Biol Chem 280(32):29374-80. Epub 2005 Jun 16. 2005
42ABL1
ABL1 amplification in T-cell acute lymphoblastic leukemia.
Bernasconi P, Calatroni S, Giardini I, Inzoli A, Castagnola C, Cavigliano PM, Rocca B, Boni M, Quarna J, Zappatore R, Caresana M, Bianchessi C, Pallavicini EB, Lazzarino M.
Cancer Genet Cytogenet 162(2):146-50. 2005
43ABL1
RIN1 is an ABL tyrosine kinase activator and a regulator of epithelial-cell adhesion and migration.
Hu H, Bliss JM, Wang Y, Colicelli J.
Curr Biol. 15(9):815-23. 2005
44YTHDC1, ABL1
The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation.
Rafalska I, Zhang Z, Benderska N, Wolff H, Hartmann AM, Brack-Werner R, Stamm S.
Hum Mol Genet 13(15):1535-49. Epub 2004 Jun 02. 2004
45ABL1, NUP214, FUBP3
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia.
Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLeod RA, Drexler HG, Look AT, Gilliland DG, Michaux L, Vandenberghe P, Wlodarska I, Marynen P, Hagemeijer A.
Nat Genet 36(10):1084-9. Epub 2004 Sep 12. 2004
46ABL1
Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response.
Cao C, Leng Y, Li C, Kufe D.
J Biol Chem. 278(15):12961-7. 2003
47ABL1
Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl.
Soubeyran P, Barac A, Szymkiewicz I, Dikic I.
Biochem J. 370(Pt 1):29-34. 2003
48ABL1
Glutathione peroxidase 1 is regulated by the c-Abl and Arg tyrosine kinases.
Cao C, Leng Y, Huang W, Liu X, Kufe D.
J Biol Chem. 278(41):39609-14. 2003
49ABL1
Catalase activity is regulated by c-Abl and Arg in the oxidative stress response.
Cao C, Leng Y, Kufe D.
J Biol Chem. 278(32):29667-75. 2003
50ABL1, BRCA1
Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.
Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P.
Mol Cell Biol. 22(12):4020-32. 2002
51ABL1
Brain armadillo protein delta-catenin interacts with Abl tyrosine kinase and modulates cellular morphogenesis in response to growth factors.
Lu Q, Mukhopadhyay NK, Griffin JD, Paredes M, Medina M, Kosik KS.
J Neurosci Res. 67(5):618-24. 2002
52ABL1
Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase.
Cong F, Tang J, Hwang BJ, Vuong BQ, Chu G, Goff SP.
J Biol Chem. 277(38):34870-8. 2002
53ABL1
Li B, Cong F, Tan CP, Wang SX, Goff SP.
J Biol Chem. 277(32):28870-6. 2002
54ABL1
Association of Bcr-Abl with the proto-oncogene Vav is implicated in activation of the Rac-1 pathway.
Bassermann F, Jahn T, Miething C, Seipel P, Bai RY, Coutinho S, Tybulewicz VL, Peschel C, Duyster J.
J Biol Chem. 277(14):12437-45. 2002
55ABL1
c-Abl tyrosine kinase regulates the human Rad9 checkpoint protein in response to DNA damage.
Yoshida K, Komatsu K, Wang HG, Kufe D.
Mol Cell Biol. 22(10):3292-300. 2002
56ABL1, ETV6
Molecular cytogenetic and clinical findings in ETV6/ABL1-positive leukemia.
Van Limbergen H, Beverloo H, van Drunen E, Janssens A, Hahlen K, Poppe B, Van Roy N, Marynen P, De Paepe A, Slater R, Speleman F.
Genes Chromosomes Cancer 30(3):274-82. 2001
57ABL1, APP
The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.
Zambrano N, Bruni P, Minopoli G, Mosca R, Molino D, Russo C, Schettini G, Sudol M, Russo T.
J Biol Chem. 276(23):19787-92. 2001
58ABL1
Inhibition of c-Abl tyrosine kinase activity by filamentous actin.
Woodring PJ, Hunter T, Wang JY.
J Biol Chem. 276(29):27104-10. 2001
59ABL1
Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor.
Yu HH, Zisch AH, Dodelet VC, Pasquale EB.
Oncogene. 20(30):3995-4006. 2001
60ABL1
Specific association of Type I c-Abl with Ran GTPase in lipopolysaccharide-mediated differentiation.
Daniel R, Chung SW, Eisenstein TK, Sultzer BM, Wong PM.
Oncogene. 20(21):2618-25. 2001
61ABL1
Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress.
Ito Y, Pandey P, Sathyanarayana P, Ling P, Rana A, Weichselbaum R, Tan TH, Kufe D, Kharbanda S.
J Biol Chem. 276(21):18130-8. 2001
62ABL1
c-Abl tyrosine kinase binds and phosphorylates phospholipid scramblase 1.
Sun J, Zhao J, Schwartz MA, Wang JY, Wiedmer T, Sims PJ.
J Biol Chem. 276(31):28984-90. 2001
63ABL1
Mice deficient in abl are osteoporotic and have defects in osteoblast maturation.
Li B, Boast S, de Los Santos K, Schieren I, Quiroz M, Teitelbaum SL, M Tondravi M, Goff SP.
Nat Genet 24(3):304-8. No abstract available. 2000
64ABL1
Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor.
Bashaw GJ, Kidd T, Murray D, Pawson T, Goodman CS.
Cell. 101(7):703-15. 2000
65ABL1
Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold.
Westphal RS, Soderling SH, Alto NM, Langeberg LK, Scott JD.
EMBO J. 19(17):4589-600. 2000
66ABL1
The c-Abl tyrosine kinase is regulated downstream of the B cell antigen receptor and interacts with CD19.
Zipfel PA, Grove M, Blackburn K, Fujimoto M, Tedder TF, Pendergast AM.
J Immunol. 165(12):6872-9. 2000
67ABL1, CDK5
Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth.
Zukerberg LR, Patrick GN, Nikolic M, Humbert S, Wu CL, Lanier LM, Gertler FB, Vidal M, Van Etten RA, Tsai LH.
Neuron. 26(3):633-46. 2000
68ABL1
Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization.
Nie Y, Li HH, Bula CM, Liu X.
Mol Cell Biol. 20(3):741-8. 2000
69ABL1
Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop.
Koch A, Mancini A, Stefan M, Niedenthal R, Niemann H, Tamura T.
FEBS Lett. 469(1):72-6. 2000
70ABL1
Functional interaction between c-Abl and the p21-activated protein kinase gamma-PAK.
Roig J, Tuazon PT, Zipfel PA, Pendergast AM, Traugh JA.
Proc Natl Acad Sci U S A. 97(26):14346-51. 2000
71ABL1
Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor.
Yano H, Cong F, Birge RB, Goff SP, Chao MV.
J Neurosci Res. 59(3):356-64. 2000
72ABL1
Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase.
Kumar V, Sabatini D, Pandey P, Gingras AC, Majumder PK, Kumar M, Yuan ZM, Carmichael G, Weichselbaum R, Sonenberg N, Kufe D, Kharbanda S.
J Biol Chem. 275(15):10779-87. 2000
73ABL1
Interaction of the N-methyl-D-aspartic acid receptor NR2D subunit with the c-Abl tyrosine kinase.
Glover RT, Angiolieri M, Kelly S, Monaghan DT, Wang JY, Smithgall TE, Buller AL.
J Biol Chem. 275(17):12725-9. 2000
74ABL1
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase.
Kharbanda S, Kumar V, Dhar S, Pandey P, Chen C, Majumder P, Yuan ZM, Whang Y, Strauss W, Pandita TK, Weaver D, Kufe D.
Curr Biol. 10(10):568-75. 2000
75BCR, ABL1
The biology of chronic myeloid leukemia.
Faderl S, et al.
N Engl J Med 341(3):164-72. Review. No abstract available 1999
76ABL1, TP73
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis.
Agami R, et al.
Nature 399(6738):809-13. 1999
77BCR, ABL1
Two patients with novel BCR/ABL fusion transcripts (e8/a2 and e13/a2) resulting from translocation breakpoints within BCR exons.
How GF, et al.
Br J Haematol 105(2):434-6. 1999
78ABL1, TP73
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Yuan ZM, et al.
Nature 399(6738):814-7. 1999
79ABL1, TP73
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage.
Gong JG, et al.
Nature 399(6738):806-9. 1999
80ABL1, MAP2K6
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation.
Cong F, Goff SP.
Proc Natl Acad Sci U S A 96(24):13819-24 1999
81ABL1
Characterization of a novel member of the DOK family that binds and modulates Abl signaling.
Cong F, Yuan B, Goff SP.
Mol Cell Biol. 19(12):8314-25. 1999
82ABL1
GCKR links the Bcr-Abl oncogene and Ras to the stress-activated protein kinase pathway.
Shi CS, Tuscano JM, Witte ON, Kehrl JH.
Blood. 93(4):1338-45. 1999
83ABL1
Nuclear-cytoplasmic shuttling of C-ABL tyrosine kinase.
Taagepera S, et al.
Proc Natl Acad Sci U S A 95(13):7457-62. 1998
84ABL1
Expression, localization and functional interactions of Ku70 subunit of DNA-PK in peripheral lymphocytes and Nalm-19 cells after irradiation.
Kumaravel TS, Bharathy K, Kudoh S, Tanaka K, Kamada N.
Int J Radiat Biol. 74(4):481-9. 1998
85ABL1
Integrins regulate the association and phosphorylation of paxillin by c-Abl.
Lewis JM, Schwartz MA.
J Biol Chem. 273(23):14225-30. 1998
86ABL1
The SH2-containing adapter protein GRB10 interacts with BCR-ABL.
Bai RY, Jahn T, Schrem S, Munzert G, Weidner KM, Wang JY, Duyster J.
Oncogene. 17(8):941-8. 1998
87ABL1, ABL2, SORBS2
ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks.
Wang B, Golemis EA, Kruh GD.
J Biol Chem 272(28):17542-50. 1997
88ABL1, PAG1
The PAG gene product, a stress-induced protein with antioxidant properties, is an Abl SH3-binding protein and a physiological inhibitor of c-Abl tyrosine kinase activity.
Wen ST, Van Etten RA.
Genes Dev 11(19):2456-67. 1997
89ABL1
Interaction between ATM protein and c-Abl in response to DNA damage.
Shafman T, Khanna KK, Kedar P, Spring K, Kozlov S, Yen T, Hobson K, Gatei M, Zhang N, Watters D, Egerton M, Shiloh Y, Kharbanda S, Kufe D, Lavin MF.
Nature. 387(6632):520-3. 1997
90ABL1
The amphiphysin-like protein 1 (ALP1) interacts functionally with the cABL tyrosine kinase and may play a role in cytoskeletal regulation.
Kadlec L, Pendergast AM.
Proc Natl Acad Sci U S A. 94(23):12390-5. 1997
91ABL1
Direct binding of CRKL to BCR-ABL is not required for BCR-ABL transformation.
Heaney C, Kolibaba K, Bhat A, Oda T, Ohno S, Fanning S, Druker BJ.
89(1):297-306. 89(1):297-306. 1997
92ABL1
The Src family kinase Hck interacts with Bcr-Abl by a kinase-independent mechanism and phosphorylates the Grb2-binding site of Bcr.
Warmuth M, Bergmann M, Priess A, Häuslmann K, Emmerich B, Hallek M.
J Biol Chem. 272(52):33260-70. 1997
93ABL1
Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport.
Lewis JM, et al.
Proc Natl Acad Sci U S A 93(26):15174-9. 1996
94ABL1
c-ABL tyrosine kinase activity is regulated by association with a novel SH3-domain-binding protein.
Zhu J, Shore SK.
Mol Cell Biol. 16(12):7054-62. 1996
95ABL1
The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Kharbanda S, Bharti A, Pei D, Wang J, Pandey P, Ren R, Weichselbaum R, Walsh CT, Kufe D.
Proc Natl Acad Sci U S A. 93(14):6898-901. 1996
96ABL1, ETV6
The novel activation of ABL by fusion to an ets-related gene, TEL.
Papadopoulos P, et al.
Cancer Res 55 : 34-38. 1995
97ABL1, ETV6
The fusion of TEL and ABL in human acute lymphoblastic leukaemia is a rare event.
Janssen JWG, et al.
Br J Haematol 90 : 222-224. 1995
98ABI2, ABL1
Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity.
Dai Z, Pendergast AM.
Genes Dev 9(21):2569-82. 1995
99ABL1, CREB1
Nuclear localization of v-Abl leads to complex formation with cyclic AMP response element (CRE)-binding protein and transactivation through CRE motifs.
Birchenall-Roberts MC, Ruscetti FW, Kasper JJ, Bertolette DC 3rd, Yoo YD, Bang OS, Roberts MS, Turley JM, Ferris DK, Kim SJ.
Mol Cell Biol. 15(11):6088-99. 1995
100ABL1
The nuclear tyrosine kinase c-Abl negatively regulates cell growth.
Sawyers CL, et al.
Cell 77 : 121-131. 1994
101ABL1
Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.
Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T.
EMBO J. 13(4):764-73. 1994
102ABL1
A limited set of SH2 domains binds BCR through a high-affinity phosphotyrosine-independent interaction.
Muller AJ, Pendergast AM, Havlik MH, Puil L, Pawson T, Witte ON.
Mol Cell Biol. 12(11):5087-93. 1992
103ABL1
Application of methylase-limited partial Notl cleavage for a long-range restriction map of the human ABL locus.
Hanish J, et al.
Genomics 10 : 681-685. 1991
104ABL1
Dinucleotide repeat polymorphism at the ABL locus (9q34).
Kwiatkowski DJ.
Nucleic Acids Res 19 : 967. 1991
105ABL1
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene.
Tybulewicz VL, Crawford CE, Jackson PK, Bronson RT, Mulligan RC.
Cell. 65(7):1153-63. 1991
106ABL1
Mice homozygous for the ablm1 mutation show poor viability and depletion of selected B and T cell populations.
Schwartzberg PL, Stall AM, Hardin JD, Bowdish KS, Humaran T, Boast S, Harbison ML, Robertson EJ, Goff SP.
Cell. 65(7):1165-75. 1991
107ABL1
Stul RFLP in the human ABL locus.
Baumann R, et al.
Nucleic Acids Res 18 : 693. 1990
108ABL1, TSC1
Genetic recombination between tuberous sclerosis and oncogene v-abl.
Povey S, et al.
Lancet II : 279-280. 1988
109BCR@, ABL1
Long-range mapping of the Philadelphia chromosome by pulsed-field gel electrophoresis.
Westbrook CA, et al.
Blood 71 : 697-702. 1988
110BCR-ABL, ABL1
Unique forms of the abl tyrosine kinase distinguish Ph-1-positive CML from Ph-1-positive ALL.
Clark SS, McLaughlin J, Crist WM, Champlin R, Witte ON
Science 235 : 85-8. 1987
111BCR-ABL, ABL1
A novel c-abl protein product in Philadelphia-positive acute lymphoblastic leukaemia.
Kurzrock R, et al.
Nature 325 : 631-635. 1987
112ABL1, BCR-ABL
A novel abl protein expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia.
Chan LC, et al.
Nature 325 : 635-637. 1987
113ABL1, BCR-ABL
Genomic diversity correlates with clinical variation in Ph'-negative chronic myeloid leukaemia.
Morris CM, et al.
Nature 320 : 281-283. 1986
114BCR-ABL, ABL1
Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.
Mes-Masson AM, et al.
Proc Natl Acad Sci U S A 83 : 9768-9772. 1986
115BCR-ABL, ABL1
Molecular analysis of both translocation products of a Philadelphia-positive CML patient.
Klein A de, et al.
Nucleic Acids Res 14 : 7071-7082. 1986
116ABL1, BCR-ABL
The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript.
Grosveld G, et al.
Mol Cell Biol 6 : 607-616. 1986
117ABL1
Chromosomal localization and characterization of c-abl in the t(6;9) of acute nonlymphocytic leukemia.
Westbrook CA, et al.
Proc Natl Acad Sci U S A 82 : 8742-8746. 1985
118ABL1
Localization of the cellular oncogenes ABL, SIS, and FES on human germ-line chromosomes.
Jhanwar SC, Neel BG, Hayward WS, Chaganti RS.
Cytogenet Cell Genet 38 : 73-75. 1984
119ABL1, PDGFB
Oncogene translocation in chronic myelocytic leukemia.
Bartram CR, et al.
(HGM7) Cytogenet Cell Genet 37 : 415. 1984
120ABL1
An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.
Konopka JB, et al.
Cell 37 : 1035-1042. 1984
121ABL1
The human c-abl oncogene in the Philadelphia translocation.
Groffen J, et al.
J Cell Physiol 3(S) : 179-191. 1984
122ABL1, FES
Chromosomal localization of human cellular homologues of two viral oncogenes.
Heisterkamp N, et al.
Nature 299 : 747-749. 1982
123ABL1
A cellular oncogene is translocated to the Philadelphia chromosome in chronic myelocytic leukemia.
Klein A de, et al.
Nature 300 : 765-767. 1982