1 | ABCG5, ABCG8
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| Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.
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| Apro J, Beckman L, Angelin B, Rudling M.
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| Biochem Biophys Res Commun 461(4):592-7. doi: 10.1016/j.bbrc.2015.04.070. Epub 2015 Apr 22.
2015
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2 | ABCG5, ABCG8
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| Recent advances in understanding the STSL locus and ABCG5/ABCG8 biology.
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| Patel SB.
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| Curr Opin Lipidol 25(3):169-75. doi: 10.1097/MOL.0000000000000071. Review.
2014
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3 | ABCG5, ABCG8
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| The ABCG5/8 cholesterol transporter and myocardial infarction versus gallstone disease.
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| Stender S, Frikke-Schmidt R, Nordestgaard BG, Tybjaerg-Hansen A.
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| J Am Coll Cardiol 63(20):2121-8. doi: 10.1016/j.jacc.2013.12.055. Epub 2014 Mar 19.
2014
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4 | ABCG5, ABCG8, RNF5, SYVN1
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| Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.
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| Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H.
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| Sci Rep 4:4258. doi: 10.1038/srep04258.
2014
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5 | ABCG5, ABCG8
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| ABCG5/ABCG8 in cholesterol excretion and atherosclerosis.
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| Yu XH, Qian K, Jiang N, Zheng XL, Cayabyab FS, Tang CK.
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| Clin Chim Acta 428:82-8. doi: 10.1016/j.cca.2013.11.010. Epub 2013 Nov 16. Review.
2014
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6 | ABCA1, ABCG5, ABCG8
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| ATP-binding cassette sterol transporters are differentially expressed in normal and diseased human gallbladder.
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| Yoon JH, Choi HS, Jun DW, Yoo KS, Lee J, Yang SY, Kuver R.
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| Dig Dis Sci 58(2):431-9. doi: 10.1007/s10620-012-2481-0. Epub 2012 Nov 22.
2013
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7 | ABCG5, ABCG8
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| The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.
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| Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA.
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| J Biol Chem 287(34):28564-75. doi: 10.1074/jbc.M112.360081. Epub 2012 Jun 19.
2012
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8 | ABCG5, ABCG8
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| ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.
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| Méndez-González J, Julve J, Rotllan N, Llaverias G, Blanco-Vaca F, Escolŕ-Gil JC.
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| Biochim Biophys Acta 1811(12):1186-93. doi: 10.1016/j.bbalip.2011.07.019. Epub 2011 Aug 10.
2011
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9 | ABCG5, ABCG8, NPC2
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| NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport.
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| Yamanashi Y, Takada T, Yoshikado T, Shoda J, Suzuki H.
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| Gastroenterology 140(5):1664-74. doi: 10.1053/j.gastro.2011.01.050. Epub 2011 Mar 21.
2011
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10 | ABCG5, ABCG8
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| Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport.
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| Wang J, Grishin N, Kinch L, Cohen JC, Hobbs HH, Xie XS.
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| J Biol Chem 286(9):7308-14. doi: 10.1074/jbc.M110.210880. Epub 2011 Jan 5.
2011
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11 | ABCG5, ABCG8
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| ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis.
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| Jakulj L, Vissers MN, Tanck MW, Hutten BA, Stellaard F, Kastelein JJ, Dallinga-Thie GM.
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| J Lipid Res 51(10):3016-23. doi: 10.1194/jlr.M008128. Epub 2010 Jun 25. Review.
2010
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12 | ABCG5, ABCG8, STSL
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| Clinical observations, molecular genetic analysis, and treatment of sitosterolemia in infants and children.
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| Niu DM, Chong KW, Hsu JH, Wu TJ, Yu HC, Huang CH, Lo MY, Kwok CF, Kratz LE, Ho LT.
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| J Inherit Metab Dis 33(4):437-43. doi: 10.1007/s10545-010-9126-2. Epub 2010 Jun 3.
2010
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13 | ABCG5, ABCG8
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| Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8.
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| Johnson BJ, Lee JY, Pickert A, Urbatsch IL.
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| Biochemistry 49(16):3403-11. doi: 10.1021/bi902064g.
2010
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14 | ABCG5, ABCG8
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| The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease.
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| Sabeva NS, Liu J, Graf GA.
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| Curr Opin Endocrinol Diabetes Obes 16(2):172-7. Review.
2009
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15 | ABCA1, ABCG5, ABCG8, ABLP, APOB, APOB, APOC2, ARH, FDB, FHBL1, HCHOLA3, HDLDT1, LDLR, LDLRAP1, LIPAD, LPL, MTTP, PBAM, PCSK9, SLC10A2, STSL
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| Monogenic pediatric dyslipidemias: classification, genetics and clinical spectrum.
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| Rahalkar AR, Hegele RA.
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| Mol Genet Metab 93(3):282-94. Epub 2007 Nov 26. Review. 2008
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16 | ABCG8
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| A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease.
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| Buch S, Schafmayer C, Volzke H, Becker C, Franke A, von Eller-Eberstein H, Kluck C, Bassmann I, Brosch M, Lammert F, Miquel JF, Nervi F, Wittig M, Rosskopf D, Timm B, Holl C, Seeger M, ElSharawy A, Lu T, Egberts J, Fandrich F, Folsch UR, Krawczak M, Schreiber S, Nurnberg P, Tepel J, Hampe J.
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| Nat Genet 39(8):995-9. Epub 2007 Jul 15. 2007
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17 | ABCG5, ABCG8
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| Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8.
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| Wang Z, Stalcup LD, Harvey BJ, Weber J, Chloupkova M, Dumont ME, Dean M, Urbatsch IL.
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| Biochemistry 45(32):9929-39. 2006
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18 | ABCG5, ABCG8, STSL, ABCB6
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| ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile.
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| Langheim S, Yu L, von Bergmann K, Lutjohann D, Xu F, Hobbs HH, Cohen JC.
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| J Lipid Res 46(8):1732-8. Epub 2005 Jun 1. 2005
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19 | ABCG5, ABCG8
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| Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion.
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| Yu L, Gupta S, Xu F, Liverman AD, Moschetta A, Mangelsdorf DJ, Repa JJ, Hobbs HH, Cohen JC.
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| J Biol Chem 280(10):8742-7. Epub 2004 Dec 16. 2005
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20 | ABCG5, ABCG8, STSL
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| Phenotypic heterogeneity of sitosterolemia.
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| Wang J, Joy T, Mymin D, Frohlich J, Hegele RA.
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| J Lipid Res 45(12):2361-7. Epub 2004 Sep 16. 2004
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21 | ABCG5, ABCG8
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| ABCG5 and ABCG8 are expressed in gallbladder epithelial cells.
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| Tauscher A, Kuver R.
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| Biochem Biophys Res Commun 307(4):1021-8. 2003
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22 | ABCG5, ABCG8
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| ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.
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| Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, Hobbs HH.
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| J Biol Chem 278(48):48275-82. Epub 2003 Sep 22. 2003
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23 | ABCG5, ABCG8, STSL
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| Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
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| Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ.
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| J Biol Chem 277(21):18793-800. Epub 2002 Mar 18. 2002
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24 | ABCG5, ABCG8, STSL
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| Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia.
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| Hubacek JA, Berge KE, Cohen JC, Hobbs HH.
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| Hum Mutat 18(4):359-60. 2001
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25 | ABCG5, ABCG8, SSDI, STS
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| Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.
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| Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH.
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| Science 290(5497):1771-5. 2000
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