1 | ABCG5, ABCG8
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| Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.
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| Apro J, Beckman L, Angelin B, Rudling M.
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| Biochem Biophys Res Commun 461(4):592-7. doi: 10.1016/j.bbrc.2015.04.070. Epub 2015 Apr 22.
2015
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2 | ABCG5, ABCG8
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| Recent advances in understanding the STSL locus and ABCG5/ABCG8 biology.
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| Patel SB.
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| Curr Opin Lipidol 25(3):169-75. doi: 10.1097/MOL.0000000000000071. Review.
2014
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3 | ABCG5, ABCG8
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| The ABCG5/8 cholesterol transporter and myocardial infarction versus gallstone disease.
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| Stender S, Frikke-Schmidt R, Nordestgaard BG, Tybjaerg-Hansen A.
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| J Am Coll Cardiol 63(20):2121-8. doi: 10.1016/j.jacc.2013.12.055. Epub 2014 Mar 19.
2014
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4 | ABCG5, ABCG8, RNF5, SYVN1
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| Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.
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| Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H.
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| Sci Rep 4:4258. doi: 10.1038/srep04258.
2014
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5 | ABCG5, ABCG8
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| ABCG5/ABCG8 in cholesterol excretion and atherosclerosis.
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| Yu XH, Qian K, Jiang N, Zheng XL, Cayabyab FS, Tang CK.
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| Clin Chim Acta 428:82-8. doi: 10.1016/j.cca.2013.11.010. Epub 2013 Nov 16. Review.
2014
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6 | ABCA1, ABCG5, ABCG8
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| ATP-binding cassette sterol transporters are differentially expressed in normal and diseased human gallbladder.
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| Yoon JH, Choi HS, Jun DW, Yoo KS, Lee J, Yang SY, Kuver R.
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| Dig Dis Sci 58(2):431-9. doi: 10.1007/s10620-012-2481-0. Epub 2012 Nov 22.
2013
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7 | ABCG5, ABCG8
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| The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.
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| Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA.
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| J Biol Chem 287(34):28564-75. doi: 10.1074/jbc.M112.360081. Epub 2012 Jun 19.
2012
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8 | ABCG5, ABCG8
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| ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.
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| Méndez-González J, Julve J, Rotllan N, Llaverias G, Blanco-Vaca F, Escolŕ-Gil JC.
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| Biochim Biophys Acta 1811(12):1186-93. doi: 10.1016/j.bbalip.2011.07.019. Epub 2011 Aug 10.
2011
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9 | ABCG5, ABCG8, NPC2
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| NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport.
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| Yamanashi Y, Takada T, Yoshikado T, Shoda J, Suzuki H.
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| Gastroenterology 140(5):1664-74. doi: 10.1053/j.gastro.2011.01.050. Epub 2011 Mar 21.
2011
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10 | ABCG5, ABCG8
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| Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport.
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| Wang J, Grishin N, Kinch L, Cohen JC, Hobbs HH, Xie XS.
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| J Biol Chem 286(9):7308-14. doi: 10.1074/jbc.M110.210880. Epub 2011 Jan 5.
2011
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11 | ABCG5, ABCG8
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| ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis.
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| Jakulj L, Vissers MN, Tanck MW, Hutten BA, Stellaard F, Kastelein JJ, Dallinga-Thie GM.
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| J Lipid Res 51(10):3016-23. doi: 10.1194/jlr.M008128. Epub 2010 Jun 25. Review.
2010
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12 | ABCG5, ABCG8, STSL
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| Clinical observations, molecular genetic analysis, and treatment of sitosterolemia in infants and children.
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| Niu DM, Chong KW, Hsu JH, Wu TJ, Yu HC, Huang CH, Lo MY, Kwok CF, Kratz LE, Ho LT.
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| J Inherit Metab Dis 33(4):437-43. doi: 10.1007/s10545-010-9126-2. Epub 2010 Jun 3.
2010
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13 | ABCG5, ABCG8
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| Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8.
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| Johnson BJ, Lee JY, Pickert A, Urbatsch IL.
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| Biochemistry 49(16):3403-11. doi: 10.1021/bi902064g.
2010
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14 | ABCG5, ABCG8
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| The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease.
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| Sabeva NS, Liu J, Graf GA.
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| Curr Opin Endocrinol Diabetes Obes 16(2):172-7. Review.
2009
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15 | ABCA1, ABCG5, ABCG8, ABLP, APOB, APOB, APOC2, ARH, FDB, FHBL1, HCHOLA3, HDLDT1, LDLR, LDLRAP1, LIPAD, LPL, MTTP, PBAM, PCSK9, SLC10A2, STSL
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| Monogenic pediatric dyslipidemias: classification, genetics and clinical spectrum.
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| Rahalkar AR, Hegele RA.
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| Mol Genet Metab 93(3):282-94. Epub 2007 Nov 26. Review. 2008
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16 | ABCG5, ABCG8
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| Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8.
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| Wang Z, Stalcup LD, Harvey BJ, Weber J, Chloupkova M, Dumont ME, Dean M, Urbatsch IL.
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| Biochemistry 45(32):9929-39. 2006
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17 | ABCG5, ABCG8, STSL, ABCB6
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| ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile.
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| Langheim S, Yu L, von Bergmann K, Lutjohann D, Xu F, Hobbs HH, Cohen JC.
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| J Lipid Res 46(8):1732-8. Epub 2005 Jun 1. 2005
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18 | ABCG5, ABCG8
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| Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion.
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| Yu L, Gupta S, Xu F, Liverman AD, Moschetta A, Mangelsdorf DJ, Repa JJ, Hobbs HH, Cohen JC.
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| J Biol Chem 280(10):8742-7. Epub 2004 Dec 16. 2005
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19 | ABCG5, ABCG8, STSL
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| Phenotypic heterogeneity of sitosterolemia.
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| Wang J, Joy T, Mymin D, Frohlich J, Hegele RA.
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| J Lipid Res 45(12):2361-7. Epub 2004 Sep 16. 2004
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20 | ABCG5, ABCG8
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| ABCG5 and ABCG8 are expressed in gallbladder epithelial cells.
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| Tauscher A, Kuver R.
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| Biochem Biophys Res Commun 307(4):1021-8. 2003
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21 | ABCG5, ABCG8
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| ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.
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| Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, Hobbs HH.
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| J Biol Chem 278(48):48275-82. Epub 2003 Sep 22. 2003
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22 | ABCG5, ABCG8, STSL
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| Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
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| Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ.
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| J Biol Chem 277(21):18793-800. Epub 2002 Mar 18. 2002
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23 | ABCG5
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| Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.
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| Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB.
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| Nat Genet 27(1):79-83. 2001
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24 | ABCG5
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| An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.
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| Shulenin S, Schriml LM, Remaley AT, Fojo S, Brewer B, Allikmets R, Dean M.
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| Cytogenet Cell Genet 92(3-4):204-8. 2001
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25 | ABCG5, ABCG8, STSL
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| Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia.
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| Hubacek JA, Berge KE, Cohen JC, Hobbs HH.
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| Hum Mutat 18(4):359-60. 2001
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26 | ABCG5, ABCG8, SSDI, STS
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| Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.
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| Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH.
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| Science 290(5497):1771-5. 2000
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