Citations for
1ABCG5, ABCG8
Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.
Apro J, Beckman L, Angelin B, Rudling M.
Biochem Biophys Res Commun 461(4):592-7. doi: 10.1016/j.bbrc.2015.04.070. Epub 2015 Apr 22. 2015
2ABCG5, ABCG8
Recent advances in understanding the STSL locus and ABCG5/ABCG8 biology.
Patel SB.
Curr Opin Lipidol 25(3):169-75. doi: 10.1097/MOL.0000000000000071. Review. 2014
3ABCG5, ABCG8
The ABCG5/8 cholesterol transporter and myocardial infarction versus gallstone disease.
Stender S, Frikke-Schmidt R, Nordestgaard BG, Tybjaerg-Hansen A.
J Am Coll Cardiol 63(20):2121-8. doi: 10.1016/j.jacc.2013.12.055. Epub 2014 Mar 19. 2014
4ABCG5, ABCG8, RNF5, SYVN1
Inhibition of post-translational N-glycosylation by HRD1 that controls the fate of ABCG5/8 transporter.
Suzuki S, Shuto T, Sato T, Kaneko M, Takada T, Suico MA, Cyr DM, Suzuki H, Kai H.
Sci Rep 4:4258. doi: 10.1038/srep04258. 2014
5ABCG5, ABCG8
ABCG5/ABCG8 in cholesterol excretion and atherosclerosis.
Yu XH, Qian K, Jiang N, Zheng XL, Cayabyab FS, Tang CK.
Clin Chim Acta 428:82-8. doi: 10.1016/j.cca.2013.11.010. Epub 2013 Nov 16. Review. 2014
6ABCA1, ABCG5, ABCG8
ATP-binding cassette sterol transporters are differentially expressed in normal and diseased human gallbladder.
Yoon JH, Choi HS, Jun DW, Yoo KS, Lee J, Yang SY, Kuver R.
Dig Dis Sci 58(2):431-9. doi: 10.1007/s10620-012-2481-0. Epub 2012 Nov 22. 2013
7ABCG5, ABCG8
The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation.
Su K, Sabeva NS, Liu J, Wang Y, Bhatnagar S, van der Westhuyzen DR, Graf GA.
J Biol Chem 287(34):28564-75. doi: 10.1074/jbc.M112.360081. Epub 2012 Jun 19. 2012
8ABCG5, ABCG8
ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.
Méndez-González J, Julve J, Rotllan N, Llaverias G, Blanco-Vaca F, Escolŕ-Gil JC.
Biochim Biophys Acta 1811(12):1186-93. doi: 10.1016/j.bbalip.2011.07.019. Epub 2011 Aug 10. 2011
9ABCG5, ABCG8, NPC2
NPC2 regulates biliary cholesterol secretion via stimulation of ABCG5/G8-mediated cholesterol transport.
Yamanashi Y, Takada T, Yoshikado T, Shoda J, Suzuki H.
Gastroenterology 140(5):1664-74. doi: 10.1053/j.gastro.2011.01.050. Epub 2011 Mar 21. 2011
10ABCG5, ABCG8
Sequences in the nonconsensus nucleotide-binding domain of ABCG5/ABCG8 required for sterol transport.
Wang J, Grishin N, Kinch L, Cohen JC, Hobbs HH, Xie XS.
J Biol Chem 286(9):7308-14. doi: 10.1074/jbc.M110.210880. Epub 2011 Jan 5. 2011
11ABCG5, ABCG8
ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis.
Jakulj L, Vissers MN, Tanck MW, Hutten BA, Stellaard F, Kastelein JJ, Dallinga-Thie GM.
J Lipid Res 51(10):3016-23. doi: 10.1194/jlr.M008128. Epub 2010 Jun 25. Review. 2010
12ABCG5, ABCG8, STSL
Clinical observations, molecular genetic analysis, and treatment of sitosterolemia in infants and children.
Niu DM, Chong KW, Hsu JH, Wu TJ, Yu HC, Huang CH, Lo MY, Kwok CF, Kratz LE, Ho LT.
J Inherit Metab Dis 33(4):437-43. doi: 10.1007/s10545-010-9126-2. Epub 2010 Jun 3. 2010
13ABCG5, ABCG8
Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8.
Johnson BJ, Lee JY, Pickert A, Urbatsch IL.
Biochemistry 49(16):3403-11. doi: 10.1021/bi902064g. 2010
14ABCG5, ABCG8
The ABCG5 ABCG8 sterol transporter and phytosterols: implications for cardiometabolic disease.
Sabeva NS, Liu J, Graf GA.
Curr Opin Endocrinol Diabetes Obes 16(2):172-7. Review. 2009
15ABCA1, ABCG5, ABCG8, ABLP, APOB, APOB, APOC2, ARH, FDB, FHBL1, HCHOLA3, HDLDT1, LDLR, LDLRAP1, LIPAD, LPL, MTTP, PBAM, PCSK9, SLC10A2, STSL
Monogenic pediatric dyslipidemias: classification, genetics and clinical spectrum.
Rahalkar AR, Hegele RA.
Mol Genet Metab 93(3):282-94. Epub 2007 Nov 26. Review. 2008
16ABCG5, ABCG8
Purification and ATP hydrolysis of the putative cholesterol transporters ABCG5 and ABCG8.
Wang Z, Stalcup LD, Harvey BJ, Weber J, Chloupkova M, Dumont ME, Dean M, Urbatsch IL.
Biochemistry 45(32):9929-39. 2006
17ABCG5, ABCG8, STSL, ABCB6
ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile.
Langheim S, Yu L, von Bergmann K, Lutjohann D, Xu F, Hobbs HH, Cohen JC.
J Lipid Res 46(8):1732-8. Epub 2005 Jun 1. 2005
18ABCG5, ABCG8
Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion.
Yu L, Gupta S, Xu F, Liverman AD, Moschetta A, Mangelsdorf DJ, Repa JJ, Hobbs HH, Cohen JC.
J Biol Chem 280(10):8742-7. Epub 2004 Dec 16. 2005
19ABCG5, ABCG8, STSL
Phenotypic heterogeneity of sitosterolemia.
Wang J, Joy T, Mymin D, Frohlich J, Hegele RA.
J Lipid Res 45(12):2361-7. Epub 2004 Sep 16. 2004
20ABCG5, ABCG8
ABCG5 and ABCG8 are expressed in gallbladder epithelial cells.
Tauscher A, Kuver R.
Biochem Biophys Res Commun 307(4):1021-8. 2003
21ABCG5, ABCG8
ABCG5 and ABCG8 are obligate heterodimers for protein trafficking and biliary cholesterol excretion.
Graf GA, Yu L, Li WP, Gerard R, Tuma PL, Cohen JC, Hobbs HH.
J Biol Chem 278(48):48275-82. Epub 2003 Sep 22. 2003
22ABCG5, ABCG8, STSL
Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.
Repa JJ, Berge KE, Pomajzl C, Richardson JA, Hobbs H, Mangelsdorf DJ.
J Biol Chem 277(21):18793-800. Epub 2002 Mar 18. 2002
23ABCG5
Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption.
Lee MH, Lu K, Hazard S, Yu H, Shulenin S, Hidaka H, Kojima H, Allikmets R, Sakuma N, Pegoraro R, Srivastava AK, Salen G, Dean M, Patel SB.
Nat Genet 27(1):79-83. 2001
24ABCG5
An ATP-binding cassette gene (ABCG5) from the ABCG (White) gene subfamily maps to human chromosome 2p21 in the region of the Sitosterolemia locus.
Shulenin S, Schriml LM, Remaley AT, Fojo S, Brewer B, Allikmets R, Dean M.
Cytogenet Cell Genet 92(3-4):204-8. 2001
25ABCG5, ABCG8, STSL
Mutations in ATP-cassette binding proteins G5 (ABCG5) and G8 (ABCG8) causing sitosterolemia.
Hubacek JA, Berge KE, Cohen JC, Hobbs HH.
Hum Mutat 18(4):359-60. 2001
26ABCG5, ABCG8, SSDI, STS
Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters.
Berge KE, Tian H, Graf GA, Yu L, Grishin NV, Schultz J, Kwiterovich P, Shan B, Barnes R, Hobbs HH.
Science 290(5497):1771-5. 2000