Citations for
1ABCA1, ABCG1, HECTD1
The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.
Aleidi SM, Yang A, Sharpe LJ, Rao G, Cochran BJ, Rye KA, Kockx M, Brown AJ, Gelissen IC.
Biochim Biophys Acta 1863(4):359-368. doi: 10.1016/j.bbalip.2017.12.011. Epub 2018 Jan 3. 2018
2ABCG1, CAV1
Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.
Gu HM, Wang FQ, Zhang DW.
Biochim Biophys Acta 1841(6):847-58. doi: 10.1016/j.bbalip.2014.02.002. Epub 2014 Feb 24. 2014
3ABCA1, ABCG1, ABCG4
ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane.
Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, Matsuo M.
PLoS One 9(10):e109886. doi: 10.1371/journal.pone.0109886. eCollection 2014. 2014
4ABCG1, IL22, S100A12, S100A8, S100A9
IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1.
Chellan B, Yan L, Sontag TJ, Reardon CA, Hofmann Bowman MA.
J Lipid Res 55(3):443-54. doi: 10.1194/jlr.M044305. Epub 2013 Dec 23. 2014
5ABCG1
ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin.
Hirayama H, Kimura Y, Kioka N, Matsuo M, Ueda K.
J Lipid Res 54(2):496-502. doi: 10.1194/jlr.M033209. Epub 2012 Nov 19. 2013
6ABCG1
ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development.
Sag D, Wingender G, Nowyhed H, Wu R, Gebre AK, Parks JS, Kronenberg M, Hedrick CC.
J Immunol 189(11):5129-38. doi: 10.4049/jimmunol.1201570. Epub 2012 Oct 24. 2012
7ABCG1
Protein kinase A modulates the activity of a major human isoform of ABCG1.
Gelissen IC, Sharpe LJ, Sandoval C, Rao G, Kockx M, Kritharides L, Jessup W, Brown AJ.
J Lipid Res 53(10):2133-40. doi: 10.1194/jlr.M028795. Epub 2012 Aug 7. 2012
8ABCG1
ATP binding cassette transporter G1 deletion induces IL-17-dependent dysregulation of pulmonary adaptive immunity.
Draper DW, Gowdy KM, Madenspacher JH, Wilson RH, Whitehead GS, Nakano H, Pandiri AR, Foley JF, Remaley AT, Cook DN, Fessler MB.
J Immunol 188(11):5327-36. doi: 10.4049/jimmunol.1101605. Epub 2012 Apr 25. 2012
9ABCA1, ABCG1
Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.
Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Wellington CL, LütJohann D, Johnson JD, Brunham LR, Verchere CB, Hayden MR.
Diabetes 61(3):659-64. doi: 10.2337/db11-1341. Epub 2012 Feb 7. 2012
10ABCG1
Identification of an amino acid residue in ATP-binding cassette transport G1 critical for mediating cholesterol efflux.
Gao X, Gu H, Li G, Rye KA, Zhang DW.
Biochim Biophys Acta 1821(3):552-9. doi: 10.1016/j.bbalip.2011.07.012. Epub 2011 Jul 29. 2012
11ABCG1
ATP binding cassette transporter G1 (ABCG1) is an intracellular sterol transporter.
Tarling EJ, Edwards PA.
Proc Natl Acad Sci U S A 108(49):19719-24. doi: 10.1073/pnas.1113021108. Epub 2011 Nov 17. 2011
12ABCG1, EDN1
Endothelin-1 exacerbates lipid accumulation by increasing the protein degradation of the ATP-binding cassette transporter G1 in macrophages.
Lin CY, Lee TS, Chen CC, Chang CA, Lin YJ, Hsu YP, Ho LT.
J Cell Physiol 226(8):2198-205. doi: 10.1002/jcp.22556. 2011
13ABCG1
ATP binding cassette G1-dependent cholesterol efflux during inflammation.
de Beer MC, Ji A, Jahangiri A, Vaughan AM, de Beer FC, van der Westhuyzen DR, Webb NR.
J Lipid Res 52(2):345-53. doi: 10.1194/jlr.M012328. Epub 2010 Dec 7. 2011
14ABCG1
Regulation of ABCG1 expression in human keratinocytes and murine epidermis.
Jiang YJ, Lu B, Tarling EJ, Kim P, Man MQ, Crumrine D, Edwards PA, Elias PM, Feingold KR.
J Lipid Res 51(11):3185-95. doi: 10.1194/jlr.M006445. Epub 2010 Aug 1. 2010
15ABCA1, ABCG1
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.
Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR.
Science 328(5986):1689-93. doi: 10.1126/science.1189731. Epub 2010 May 20. 2010
16ABCG1
ABCG1 deficiency in mice promotes endothelial activation and monocyte-endothelial interactions.
Whetzel AM, Sturek JM, Nagelin MH, Bolick DT, Gebre AK, Parks JS, Bruce AC, Skaflen MD, Hedrick CC.
Arterioscler Thromb Vasc Biol 30(4):809-17. doi: 10.1161/ATVBAHA.109.199166. Epub 2010 Jan 28. 2010
17ABCG1
ATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.
Armstrong AJ, Gebre AK, Parks JS, Hedrick CC.
J Immunol 184(1):173-83. doi: 10.4049/jimmunol.0902372. Epub 2009 Nov 30. 2010
18ABCG1, ABCG4
Differential expression and function of ABCG1 and ABCG4 during development and aging.
Bojanic DD, Tarr PT, Gale GD, Smith DJ, Bok D, Chen B, Nusinowitz S, Lövgren-Sandblom A, Björkhem I, Edwards PA.
J Lipid Res 51(1):169-81. doi: 10.1194/M900250-JLR200. Epub . 2010
19ABCG1
Small discoidal pre-beta1 HDL particles are efficient acceptors of cell cholesterol via ABCA1 and ABCG1.
Favari E, Calabresi L, Adorni MP, Jessup W, Simonelli S, Franceschini G, Bernini F.
Biochemistry 48(46):11067-74. 2009
20ABCG1, GPS2
GPS2 is required for cholesterol efflux by triggering histone demethylation, LXR recruitment, and coregulator assembly at the ABCG1 locus.
Jakobsson T, Venteclef N, Toresson G, Damdimopoulos AE, Ehrlund A, Lou X, Sanyal S, Steffensen KR, Gustafsson JA, Treuter E.
Mol Cell 34(4):510-8. doi: 10.1016/j.molcel.2009.05.006. 2009
21ABCG1
Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element.
Uehara Y, Miura S, von Eckardstein A, Abe S, Fujii A, Matsuo Y, Rust S, Lorkowski S, Assmann G, Yamada T, Saku K.
Atherosclerosis 191(1):11-21. Epub 2006 May 30. 2007
22ABCG1
ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines.
Sporstol M, Mousavi SA, Eskild W, Roos N, Berg T.
BMC Mol Biol 8:5. 2007
23ABCG1
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation.
Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, Jessup W, Hill AF, Garner B.
J Biol Chem 282(5):2851-61. Epub 2006 Nov 22. 2007
24BACE1, ABCG1
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL.
J Lipid Res 48(5):1022-34. Epub 2007 Feb 10. 2007
25ABCG1
Expression and functional characterization of ABCG1 splice variant ABCG1(666).
Engel T, Bode G, Lueken A, Knop M, Kannenberg F, Nofer JR, Assmann G, Seedorf U.
FEBS Lett 580(18):4551-9. Epub 2006 Jul 13. 2006
26ABCG1
Deletion of the transmembrane transporter ABCG1 results in progressive pulmonary lipidosis.
Bald‡n A, Tarr P, Vales CS, Frank J, Shimotake TK, Hawgood S, Edwards PA.
J Biol Chem 281(39):29401-10. Epub 2006 Aug 3. 2006
27ABCA1, ABCG1, ABCG4
ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL.
Vaughan AM, Oram JF.
J Lipid Res 47(11):2433-43. Epub 2006 Aug 10. 2006
28ABCA1, ABCG1
Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.
Kobayashi A, Takanezawa Y, Hirata T, Shimizu Y, Misasa K, Kioka N, Arai H, Ueda K, Matsuo M.
J Lipid Res. 47(8):1791-802. 2006
29ABCG1
ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation
Kennedy MA, Barrera GC, Nakamura K, Baldan A, Tarr P, Fishbein MC, Frank J, Francone OL, Edwards PA.
Cell metabolism 1(2):121-131. 2005
30ABCG1
The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver.
Sabol SL, Brewer HB Jr, Santamarina-Fojo S.
J Lipid Res 46(10):2151-67. Epub 2005 Jul 16. 2005
31ABCG1, POSTN, SPINK5, S100A9, CD24, TGM3, EHF, ZNF185
Identification of 9 genes differentially expressed in head and neck squamous cell carcinoma.
Gonzalez HE, Gujrati M, Frederick M, Henderson Y, Arumugam J, Spring PW, Mitsudo K, Kim HW, Clayman GL.
Arch Otolaryngol Head Neck Surg 129(7):754-9. 2003
32ABCA7, ABCC1, ABCC2, ABCC3, ABCG1, ABCB1
Adenosine triphosphate binding cassette (ABC) transporters are expressed and regulated during terminal keratinocyte differentiation: a potential role for ABCA7 in epidermal lipid reorganization.
Kielar D, Kaminski WE, Liebisch G, Piehler A, Wenzel JJ, Mohle C, Heimerl S, Langmann T, Friedrich SO, Bottcher A, Barlage S, Drobnik W, Schmitz G.
J Invest Dermatol 121(3):465-74. 2003
33ABCG1
Genomic sequence and structure of the human ABCG1 (ABC8) gene.
Lorkowski S, Rust S, Engel T, Jung E, Tegelkamp K, Galinski EA, Assmann G, Cullen P.
Biochem Biophys Res Commun 280(1):121-31. 2001
34ABCG1
Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease.
Lorkowski S, Kratz M, Wenner C, Schmidt R, Weitkamp B, Fobker M, Reinhardt J, Rauterberg J, Galinski EA, Cullen P.
Biochem Biophys Res Commun 283(4):821-30. 2001
35ABCG1
Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein.
Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA.
J Biol Chem 276(42):39438-47. 2001
36ABCG1
ABCG1 (ABC8), the human homolog of the drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport.
Klucken J, Buchler C, Orso E, Kaminski WE, Porsch-Ozcurumez M, Liebisch G, Kapinsky M, Diederich W, Drobnik W, Dean M, Allikmets R, Schmitz G.
Proc Natl Acad Sci U S A 97(2):817-22 2000
37ABCG1
Genomic organization and characterization of the promoter of the human ATP-binding cassette transporter-G1 (ABCG1) gene.
Langmann T, Porsch-Ozcurumez M, Unkelbach U, Klucken J, Schmitz G.
Biochim Biophys Acta 1494(1-2):175-80. 2000
38ABCG1
Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3.
Chen H, Rossier C, Lalioti MD, Lynn A, Chakravarti A, Perrin G, Antonarakis SE.
Am J Hum Genet 59(1):66-75. 1996