| 1 | ABCB11, NR0B2, NR1H4, SLC10A1
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| The nuclear receptor FXR, but not LXR, up-regulates bile acid transporter expression in non-alcoholic fatty liver disease.
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| Aguilar-Olivos NE, Carrillo-Córdova D, Oria-Hernández J, Sánchez-Valle V, Ponciano-Rodríguez G, Ramírez-Jaramillo M, Chablé-Montero F, Chávez-Tapia NC, Uribe M, Méndez-Sánchez N.
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| Ann Hepatol 14(4):487-93.
2015
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| 2 | ABCB11, ATP8B1
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| Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content.
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| Paulusma CC, de Waart DR, Kunne C, Mok KS, Elferink RP.
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| J Biol Chem 284(15):9947-54. Epub 2009 Feb 19.
2009
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| 3 | ABCB11
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| Genetic variations of the ABC transporter gene ABCB11 encoding the human bile salt export pump (BSEP) in a Japanese population.
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| Kim SR, Saito Y, Itoda M, Maekawa K, Kawamoto M, Kamatani N, Ozawa S, Sawada J.
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| Drug Metab Pharmacokinet 24(3):277-81.
2009
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| 4 | ABCB11, PFIC2
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| Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing.
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| Byrne JA, Strautnieks SS, Ihrke G, Pagani F, Knisely AS, Linton KJ, Mieli-Vergani G, Thompson RJ.
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| Hepatology 49(2):553-67. 2009
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| 5 | ABCB11
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| Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy.
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| Dixon PH, van Mil SW, Chambers J, Strautnieks S, Thompson RJ, Lammert F, Kubitz R, Keitel V, Glantz A, Mattsson LA, Marschall HU, Molokhia M, Moore GE, Linton KJ, Williamson C.
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| Gut 58(4):537-44. Epub 2008 Nov 5.
2009
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| 6 | ABCB11, ABCB4
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| Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls.
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| Acalovschi M, Tirziu S, Chiorean E, Krawczyk M, Grünhage F, Lammert F.
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| Lipids 44(6):521-6. Epub 2009 Apr 30.
2009
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| 7 | ABCB11, PFIC2
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| Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families.
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| Strautnieks SS, Byrne JA, Pawlikowska L, Cebecauerová D, Rayner A, Dutton L, Meier Y, Antoniou A, Stieger B, Arnell H, Ozçay F, Al-Hussaini HF, Bassas AF, Verkade HJ, Fischler B, Németh A, Kotalová R, Shneider BL, Cielecka-Kuszyk J, McClean P, Whitington PF, Sokal E, Jirsa M, Wali SH, Jankowska I, Paw³owska J, Mieli-Vergani G, Knisely AS, Bull LN, Thompson RJ.
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| Gastroenterology 134(4):1203-14. Epub 2008 Jan 18.
2008
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| 8 | ABCB11, G6PC2
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| Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
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| Chen WM, Erdos MR, Jackson AU, Saxena R, Sanna S, Silver KD, Timpson NJ, Hansen T, Orrù M, Grazia Piras M, Bonnycastle LL, Willer CJ, Lyssenko V, Shen H, Kuusisto J, Ebrahim S, Sestu N, Duren WL, Spada MC, Stringham HM, Scott LJ, Olla N, Swift AJ, Najjar S, Mitchell BD, Lawlor DA, Smith GD, Ben-Shlomo Y, Andersen G, Borch-Johnsen K, Jørgensen T, Saramies J, Valle TT, Buchanan TA, Shuldiner AR, Lakatta E, Bergman RN, Uda M, Tuomilehto J, Pedersen O, Cao A, Groop L, Mohlke KL, Laakso M, Schlessinger D, Collins FS, Altshuler D, Abecasis GR, Boehnke M, Scuteri A, Watanabe RM.
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| J Clin Invest 118(7):2620-8.
2008
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| 9 | ABCB11, ABCB4
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| Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury.
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| Lang C, Meier Y, Stieger B, Beuers U, Lang T, Kerb R, Kullak-Ublick GA, Meier PJ, Pauli-Magnus C.
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| Pharmacogenet Genomics 17(1):47-60.
2007
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| 10 | ABCB11, SLC10A1
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| Regulation of hepatic bile acid transporters Ntcp and Bsep expression.
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| Cheng X, Buckley D, Klaassen CD.
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| Biochem Pharmacol 74(11):1665-76. Epub 2007 Aug 19.
2007
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| 11 | ABCB11, PFIC2, ABCB4
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| Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy.
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| Keitel V, Vogt C, Haussinger D, Kubitz R.
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| Gastroenterology 131(2):624-9. 2006
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| 12 | ABCB11, PFIC2
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| Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency.
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| Knisely AS, Strautnieks SS, Meier Y, Stieger B, Byrne JA, Portmann BC, Bull LN, Pawlikowska L, Bilezikci B, Ozcay F, Laszlo A, Tiszlavicz L, Moore L, Raftos J, Arnell H, Fischler B, Nemeth A, Papadogiannakis N, Cielecka-Kuszyk J, Jankowska I, Pawlowska J, Melin-Aldana H, Emerick KM, Whitington PF, Mieli-Vergani G, Thompson RJ.
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| Hepatology 44(2):478-86. 2006
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| 13 | ABCB11, PFIC2
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| High-speed screening and QSAR analysis of human ATP-binding cassette transporter ABCB11 (bile salt export pump) to predict drug-induced intrahepatic cholestasis.
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| Hirano H, Kurata A, Onishi Y, Sakurai A, Saito H, Nakagawa H, Nagakura M, Tarui S, Kanamori Y, Kitajima M, Ishikawa T.
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| Mol Pharm 3(3):252-65. 2006
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| 14 | PFIC2, ABCB11
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| Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.
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| Hayashi H, Takada T, Suzuki H, Akita H, Sugiyama Y.
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| Hepatology 41(4):916-24. 2005
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| 15 | ABCB11, PFIC2
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| Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11.
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| van Mil SW, van der Woerd WL, van der Brugge G, Sturm E, Jansen PL, Bull LN, van den Berg IE, Berger R, Houwen RH, Klomp LW.
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| Gastroenterology 127(2):379-84. 2004
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| 16 | ABCB11
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| Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump.
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| Plass JR, Mol O, Heegsma J, Geuken M, Faber KN, Jansen PL, Muller M.
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| Hepatology 35(3):589-96. 2002
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| 17 | ABCB11
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| The human bile salt export pump: characterization of substrate specificity and identification of inhibitors.
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| Byrne JA, Strautnieks SS, Mieli-Vergani G, Higgins CF, Linton KJ, Thompson RJ.
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| Gastroenterology 123(5):1649-58. 2002
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| 18 | ABCA1, ABCB11, NR0B2, NR1H3, NR1H4, NR5A2, SCARB1, SLC10A1, SCARB1
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| Don't know much bile-ology.
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| Chawla A, Saez E, Evans RM.
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| Cell 103(1):1-4. No abstract available. 2000
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| 19 | ABCB11
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| The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver.
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| Gerloff T, Stieger B, Hagenbuch B, Madon J, Landmann L, Roth J, Hofmann AF, Meier PJ.
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| J Biol Chem 273 : 10046-10050. 1998
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| 20 | ABCB11, PFIC2
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| A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis.
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| Strautnieks SS, Bull LN, Knisely AS, Kocoshis SA, Dahl N, Arnell H, Sokal E, Dahan K, Childs S, Ling V, Tanner MS, Kagalwalla AF, Nemeth A, Pawlowska J, Baker A, Mieli-Vergani G, Freimer NB, Gardiner RM, Thompson RJ.
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| Nat Genet 20 : 233. 1998
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