Citations for
1ABCB1
ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux.
Margier M, Collet X, le May C, Desmarchelier C, André F, Lebrun C, Defoort C, Bluteau A, Borel P, Lespine A, Reboul E.
FASEB J. Feb;33(2):2084-2094. doi: 10.1096/fj.201800956R. Epub 2018 Sep 17 2019
2ABCB1
P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer's Disease.
Sita G, Hrelia P, Tarozzi A, Morroni F.
Oxid Med Cell Longev. 2017:7905486. doi: 10.1155/2017/7905486. Epub 2017 Nov 26 2017
3ABCB1
Loss of constitutive ABCB1 expression in breast cancer associated with worse prognosis.
Delou JMA, Vignal GM, Índio-do-Brasil V, Accioly MTS, da Silva TSL, Piranda DN, Sobral-Leite M, de Carvalho MA, Capella MAM, Vianna-Jorge R.
Breast Cancer (Dove Med Press) Jun 10;9:415-428. doi: 10.2147/BCTT.S131284. eCollection 2017 2017
4ABCB1, TLR4
ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells.
Grybauskas A, Koga T, Kuprys PV, Nolan M, McCarty R, Walker L, Green KA, Norkett WM, Yue BY, Knepper PA.
Mol Vis. Mar 5;21:201-12. eCollection 2015 2015
5ABCB1, BAALC
Low MDR1 and BAALC expression identifies a new subgroup of intermediate cytogenetic risk acute myeloid leukemia with a favorable outcome.
Guo X, Shi P, Chen F, Zha J, Liu B, Li R, Dong H, Zheng H, Xu B.
Blood Cells Mol Dis 53(3):144-8. doi: 10.1016/j.bcmd.2014.05.001. Epub 2014 May 20. 2014
6ABCB1, PPP2R3C
Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function.
Katayama K, Yamaguchi M, Noguchi K, Sugimoto Y.
Cancer Lett. Apr 1;345(1):124-31. doi: 10.1016/j.canlet.2013.12.007. Epub 2013 Dec 11 2014
7ABCB1
Low ABCB1 gene expression is an early event in colorectal carcinogenesis.
Andersen V, Vogel U, Godiksen S, Frenzel FB, Sæbø M, Hamfjord J, Kure E, Vogel LK.
PLoS One. Aug 19;8(8):e72119. doi: 10.1371/journal.pone.0072119. eCollection 2013. 2013
8ABCB1, APEX1, YBX1
Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1.
Sengupta S, Mantha AK, Mitra S, Bhakat KK.
Oncogene 30(4):482-93. Epub 2010 Sep 20. 2011
9ABCB1, OCLN, PTK2, TJP1
P-glycoprotein regulates blood-testis barrier dynamics via its effects on the occludin/zonula occludens 1 (ZO-1) protein complex mediated by focal adhesion kinase (FAK).
Su L, Mruk DD, Lui WY, Lee WM, Cheng CY.
Proc Natl Acad Sci U S A 108(49):19623-8. doi: 10.1073/pnas.1111414108. Epub 2011 Nov 21. 2011
10ABCB1, ABCC2
Cholesterol but not association with detergent resistant membranes is necessary for the transport function of MRP2/ABCC2.
Ito K, Hoekstra D, van Ijzendoorn SC.
FEBS Lett 582(30):4153-7. Epub 2008 Nov 25. 2008
11ABCB1, ABCC1, ABCG2
ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS.
Daood M, Tsai C, Ahdab-Barmada M, Watchko JF.
Neuropediatrics 39(4):211-8. Epub 2009 Jan 22.PMID: 19165709 2008
12ABCB1
Thyroid hormone receptor mediates human MDR1 gene expression-Identification of the response region essential for gene expression.
Kurose K, Saeki M, Tohkin M, Hasegawa R.
Arch Biochem Biophys 474(1):82-90. Epub 2008 Mar 25.PMID: 18395509 2008
13ABCB1
The P-glycoprotein (ABCB1) linker domain encodes high-affinity binding sequences to alpha- and beta-tubulins.
Georges E.
Biochemistry 46(25):7337-42. Epub 2007 May 27. 2007
14ABCB1
ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach.
Ho GT, Soranzo N, Nimmo ER, Tenesa A, Goldstein DB, Satsangi J.
Hum Mol Genet 15(5):797-805. Epub 2006 Jan 24. 2006
15ABCB1, HSF1
Heat shock-independent induction of multidrug resistance by heat shock factor 1.
Tchénio T, Havard M, Martinez LA, Dautry F.
Mol Cell Biol 26(2):580-91. 2006
16ABCB1
Characterization of ABC transporter ABCB1 expressed in human neural stem/progenitor cells.
Islam MO, Kanemura Y, Tajria J, Mori H, Kobayashi S, Shofuda T, Miyake J, Hara M, Yamasaki M, Okano H.
FEBS Lett 579(17):3473-80. 2005
17RUNDC3B, ABCB1
Expression of RPIP9 (Rap2 interacting protein 9) is activated in breast carcinoma and correlates with a poor prognosis.
Raguz S, De Bella MT, Slade MJ, Higgins CF, Coombes RC, YagŸe E.
Int J Cancer 117(6):934-41. 2005
18ABCB1, MVP, LRPPRC
New invMED1 element cis-activates human multidrug-related MDR1 and MVP genes, involving the LRP130 protein.
Labialle S, Dayan G, Gayet L, Rigal D, Gambrelle J, Baggetto LG.
Nucleic Acids Res 32(13):3864-76. Print 2004. 2004
19ABCB1
MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.
Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH.
Am J Hum Genet 73(6):1282-92. Epub 2003 Nov 07. 2003
20ABCA7, ABCC1, ABCC2, ABCC3, ABCG1, ABCB1
Adenosine triphosphate binding cassette (ABC) transporters are expressed and regulated during terminal keratinocyte differentiation: a potential role for ABCA7 in epidermal lipid reorganization.
Kielar D, Kaminski WE, Liebisch G, Piehler A, Wenzel JJ, Mohle C, Heimerl S, Langmann T, Friedrich SO, Bottcher A, Barlage S, Drobnik W, Schmitz G.
J Invest Dermatol 121(3):465-74. 2003
21ABCB1
Preferential expression of a mutant allele of the amplified MDR1 (ABCB1) gene in drug-resistant variants of a human sarcoma.
Chen GK, Lacayo NJ, Duran GE, Wang Y, Bangs CD, Rea S, Kovacs M, Cherry AM, Brown JM, Sikic BI.
Genes Chromosomes Cancer 34(4):372-83. 2002
22ABCB1
Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptibility to renal epithelial tumors.
Siegsmund M, Brinkmann U, Schaffeler E, Weirich G, Schwab M, Eichelbaum M, Fritz P, Burk O, Decker J, Alken P, Rothenpieler U, Kerb R, Hoffmeyer S, Brauch H.
J Am Soc Nephrol 13(7):1847-54. 2002
23ABCB1, ABCC1
Interaction of tyrosine kinase inhibitors with the human multidrug transporter proteins, MDR1 and MRP1.
Hegedus T, Orfi L, Seprodi A, Varadi A, Sarkadi B, Keri G.
Biochim Biophys Acta 1587(2-3):318-25. Review. 2002
24ABCB1
Association of 5' CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells.
Kusaba H, et al.
Eur J Biochem 262(3):924-32 1999
25ABCB1
Genetic polymorphism in MDR-1 : a tool for examining allelic expression in normal cells, unselected and drug-selected cell lines, and human tumors.
Mickley LA, et al.
Blood 91 : 1749-1756. 1998
26ABCB1, ABCB4, ADAM22, DMTF1, CROT, NADHDL1, SCNEDL, SRI
Localization of 67 exons on a YAC contig spanning 1.5 Mb around the multidrug resistance gene region of human chromosome 7q21.1.
Torigoe K, et al.
Genomics 49 : 14-22. 1998
27ABCB1
Cytogenetic and molecular characterization of random chromosomal rearrangements activating the drug resistance gene, MDRI/P-glycoprotein, in drug-selected cell lines and patients with drug refractory ALL.
Knutsen T, Mickley LA, Ried T, Green ED, du Manoir S, Schrock E, Macville M, Ning Y, Robey R, Polymeropoulos M, Torres R, Fojo T.
Genes Chromosomes Cancer 23 : 44-54. 1998
28ABCB1
Hypomethylation status of CpG sites at the promoter region and overexpression of the human MDR1 gene in acute myeloid leukemias.
Nakayama M, Wada M, Harada T, Nagayama J, Kusaba H, Ohshima K, Kozuru M, Komatsu H, Ueda R, Kuwano M.
Blood 92 : 4296-4307. 1998
29NFYA, ABCB1
Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.
Jin S, et al.
Mol Cell Biol 18(7):4377-84. 1998
30ABCB5, ABCB1
MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.
Van Helvoort A, et al.
Cell 87 : 507-517. 1996
31ABCB1
The human mdr1 (multidrug-resistance) gene harbours a long homopyrimidine homopurine sequence next to a cluster of Alu repeated sequences in intron 14.
Pauly M, et al.
Gene 153 : 299-300. 1995
32MDRE, ABCB1, ABCB4, SLC5A1, SLC5A2, SLC6A1, SLC6A2, SLC6A4, SLC6A6, SLC6A8, SLC6A9
Molecular characterization of neurotransmitter transporters.
Shafqat S, et al.
Mol Endocrinol 7 : 1517-1529. 1993
33ABCB1
Quantitative expression patterns of multidrug-resistance P-glycoprotein (MDR1) and differentially spliced cystic-fibrosis transmembrane-conductance regulator mRNA transcripts in human epithelia.
Bremer S, et al.
Eur J Biochem 206 : 137-149. 1992
34ABCB1
Appearance and detection of multiple copies of the mdr-1 gene in clinical samples of mammary carcinoma.
Lšnn U, et al.
Int J Cancer 51 : 682-686. 1992
35ABCB1
Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance.
Devine SE, et al.
Proc Natl Acad Sci U S A 89 : 4564-4568. 1992
36ABCB1
Primer-dependent amplification of mdr1 mRNA by polymerase chain reaction.
Sugawara I, et al.
Jpn J Cancer Res 83 : 131-133. 1992
37ABCB1
PCR-determined expression of the MDR1 gene in chronic lymphocytic leukemia.
Rochlitz CF, et al.
Ann Hematol 65 : 241-246. 1992
38ABCB1
Analysis of multidrug resistance (MDR-1) gene expression in chronic lymphocytic leukemia (CLL).
Shustik C, et al.
Br J Haematol 79 : 50-56. 1991
39ABCB1, ABCB4
Structure of the human MDR3 gene and physical mapping of the human MDR locus.
Lincke CR, et al.
J Biol Chem 266 : 5303-5310. 1991
40ABCB1, ABCB4
MspI/HpaII polymorphism in the human multidrug resistance gene 1.
Haber DA, et al.
Nucleic Acids Res 17 : 10142. 1989
41ABCB1, ABCB4
Structure and expression of the human MDR (P-glycoprotein) gene family.
Chin JE, et al.
Mol Cell Biol 9 : 3808-3820. 1989
42ABCB1, ABCB4
Utility of the polymerase chain reaction in detection of gene expression in drug-resistant human tumors.
Scanlon KJ, et al.
J Clin Lab Analysis 3 : 323-329. 1989
43ABCB1, ABCB4
A polymorphic HindIII site within the human multidrug resistance gene 1 (MDR1).
Yoshimoto K, Iwahana H, Yokogoshi Y, Saito S, Shiraishi M, Sekiya T, Gottesman MM, Pastan I.
Nucleic Acids Res 16 : 11850. 1988
44ABCB1, ABCB4
Detection of drug resistance in human tumors by in vitro enzymatic amplification.
Kashani-Sabet M, et al.
Cancer Res 48 : 5775-5778. 1988
45ABCB1, ABCB4
Clarification of the chromosomal assignment of the human P-glycoprotein/MDR1 gene (PGY1).
Trent JM, et al.
(HGM9) Cytogenet Cell Genet 46 : 705. 1987
46ABCB1, ABCB4
Detection of a multidrug resistant phenotype in acute non-lymphoblastic leukaemia.
Ma DDF, et al.
Lancet I : 135-137. 1987
47CFTR, MET, ABCB1, ABCB4
Mapping of DNA markers linked to the cystic fibrosis locus on the long arm of chromosome 7.
Zengerling S, et al.
Am J Hum Genet 40 : 228-236. 1987
48ABCB1, ABCB4
Chromosomal location of human P-glycoprotein gene sequences.
Bell DR, et al.
Cancer Genet Cytogenet 25 : 141-148. 1987
49ABCB1, ABCB4
Clarification of the chromosomal assignment of the human P-glycoprotein/mdr1 gene : possible coincidence with the cystic fibrosis and c-met oncogene.
Trent JM, et al.
Cancer Genet Cytogenet 26 : 187-190. 1987
50ABCB1, ABCB4
RFLPs associated with MDR2, a member of the human multidrug resistance gene family mapped to chromosome 7.
Choi K, et al.
Nucleic Acids Res 15 : 6305. 1987
51ABCB1, ABCB4
Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.
Callen DF, et al.
Hum Genet 77 : 142-144. 1987
52ABCB1, ABCB4
The mdr1 gene, responsible for multidrug-resistance, codes for P-glycoprotein.
Ueda K, et al.
Biochem Biophys Res Commun 141 : 956-962. 1986
53ABCB1, ABCB4
Localization of multidrug resistance-associated DNA sequences to human chromosome 7.
Fojo A, et al.
Somat Cell Mol Genet 12 : 415-420. 1986
54ABCB1, ABCB4
Multidrug resistance of DNA-mediated transformants is linked to transfer of the human mdr1 gene.
Shen DW, et al.
Mol Cell Biol 6 : 4039-4045. 1986
55ABCB1, ABCB4
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.
Chen C, et al.
Cell 47 : 381-389. 1986
56ABCB1, ABCB4
Chromosomal localization in normal human cells and CHO cells of asequence derived from P-glycoprotein (PGY1).
Trent J, et al.
(HGM8) Cytogenet Cell Genet 40 : 761-762. 1985