| 1 | ABCA1, ABCG1, HECTD1
|
| The E3 ubiquitin ligase, HECTD1, is involved in ABCA1-mediated cholesterol export from macrophages.
|
| Aleidi SM, Yang A, Sharpe LJ, Rao G, Cochran BJ, Rye KA, Kockx M, Brown AJ, Gelissen IC.
|
| Biochim Biophys Acta 1863(4):359-368. doi: 10.1016/j.bbalip.2017.12.011. Epub 2018 Jan 3.
2018
|
| 2 | ABCA1
|
| ABCA1 affects placental function via trophoblast and macrophage.
|
| Chengmao X, Li L, Yan L, Jie Y, Xiaoju W, Xiaohui C, Huimin G.
|
| Life Sci 191:150-156. doi: 10.1016/j.lfs.2017.10.031. Epub 2017 Oct 21.
2017
|
| 3 | ABCA1
|
| Hepatic ABCA1 deficiency is associated with delayed apolipoprotein B secretory trafficking and augmented VLDL triglyceride secretion.
|
| Liu M, Chung S, Shelness GS, Parks JS.
|
| Biochim Biophys Acta 1862(10 Pt A):1035-1043. doi: 10.1016/j.bbalip.2017.07.001. Epub 2017 Jul 8.
2017
|
| 4 | ABCA1
|
| Structure of the Human Lipid Exporter ABCA1.
|
| Qian H, Zhao X, Cao P, Lei J, Yan N, Gong X.
|
| Cell 169(7):1228-1239.e10. doi: 10.1016/j.cell.2017.05.020. Epub 2017 Jun 8.
2017
|
| 5 | ABCA1
|
| Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis.
|
| Key CC, Liu M, Kurtz CL, Chung S, Boudyguina E, Dinh TA, Bashore A, Phelan PE, Freedman BI, Osborne TF, Zhu X, Ma L, Sethupathy P, Biddinger SB, Parks JS.
|
| Cell Rep 19(10):2116-2129. doi: 10.1016/j.celrep.2017.05.032.
2017
|
| 6 | ABCA1, HDLDT1
|
| ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion.
|
| Bi X, Pashos EE, Cuchel M, Lyssenko NN, Hernandez M, Picataggi A, McParland J, Yang W, Liu Y, Yan R, Yu C, DerOhannessian SL, Phillips MC, Morrisey EE, Duncan SA, Rader DJ.
|
| EBioMedicine 18:139-145. doi: 10.1016/j.ebiom.2017.03.018. Epub 2017 Mar 14.
2017
|
| 7 | ABCA1, EEPD1, NR1H2, NR1H3
|
| EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux.
|
| Nelson JK, Koenis DS, Scheij S, Cook EC, Moeton M, Santos A, Lobaccaro JA, Baron S, Zelcer N.
|
| Arterioscler Thromb Vasc Biol 37(3):423-432. doi: 10.1161/ATVBAHA.116.308434. Epub 2017 Jan 12.
2017
|
| 8 | ABCA1, ARF6
|
| Small GTPase ARF6 Regulates Endocytic Pathway Leading to Degradation of ATP-Binding Cassette Transporter A1.
|
| Mukhamedova N, Hoang A, Cui HL, Carmichael I, Fu Y, Bukrinsky M, Sviridov D.
|
| Arterioscler Thromb Vasc Biol 36(12):2292-2303. Epub 2016 Oct 6.
2016
|
| 9 | ABCA1
|
| Abca1 deficiency protects the heart against myocardial infarction-induced injury.
|
| Louwe MC, Lammers B, Frias MA, Foks AC, de Leeuw LR, Hildebrand RB, Kuiper J, Smit JWA, Van Berkel TJC, James RW, Geerling JJ, Rensen PCN, Van Eck M.
|
| Atherosclerosis 251:159-163. doi: 10.1016/j.atherosclerosis.2016.06.023. Epub 2016 Jun 11.
2016
|
| 10 | ABCA1
|
| TSH increases synthesis of hepatic ATP-binding cassette subfamily A member 1 in hypercholesterolemia.
|
| Zhang T, Zhou L, Li CC, Shi H, Zhou X.
|
| Biochem Biophys Res Commun 476(2):75-81. doi: 10.1016/j.bbrc.2016.05.054. Epub 2016 May 11.
2016
|
| 11 | ABCA1
|
| ATP-binding cassette transporter 1 (ABCA1) deficiency decreases platelet reactivity and reduces thromboxane A2 production independently of hematopoietic ABCA1.
|
| Lhermusier T, Severin S, Van Rothem J, Garcia C, Bertrand-Michel J, Le Faouder P, Hechler B, Broccardo C, Couvert P, Chimini G, Sié P, Payrastre B.
|
| J Thromb Haemost 14(3):585-95. doi: 10.1111/jth.13247. Epub 2016 Feb 17.
2016
|
| 12 | ABCA1
|
| ABCA1 contributes to macrophage deposition of extracellular cholesterol.
|
| Jin X, Freeman SR, Vaisman B, Liu Y, Chang J, Varsano N, Addadi L, Remaley A, Kruth HS.
|
| J Lipid Res 56(9):1720-6. doi: 10.1194/jlr.M060053. Epub 2015 Jul 22.
2015
|
| 13 | ABCA1
|
| Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum.
|
| Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S.
|
| J Biol Chem 290(39):23464-77. doi: 10.1074/jbc.M115.662668. Epub 2015 Jul 20.
2015
|
| 14 | ABCA1
|
| Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease.
|
| Nordestgaard LT, Tybjærg-Hansen A, Nordestgaard BG, Frikke-Schmidt R.
|
| Alzheimers Dement 11(12):1430-1438. doi: 10.1016/j.jalz.2015.04.006. Epub 2015 Jun 13.
2015
|
| 15 | ABCA1
|
| Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1.
|
| Fond AM, Lee CS, Schulman IG, Kiss RS, Ravichandran KS.
|
| J Clin Invest 125(7):2748-58. doi: 10.1172/JCI80300. Epub 2015 Jun 15.
2015
|
| 16 | ABCA1
|
| Inhibition of ABCA1 protein degradation promotes HDL cholesterol efflux capacity and RCT and reduces atherosclerosis in mice.
|
| Huang L, Fan B, Ma A, Shaul PW, Zhu H.
|
| J Lipid Res 56(5):986-97. doi: 10.1194/jlr.M054742. Epub 2015 Mar 11.
2015
|
| 17 | ABCA1, APOA1
|
| ABCA1 and nascent HDL biogenesis.
|
| Wang S, Smith JD.
|
| Biofactors 40(6):547-54. doi: 10.1002/biof.1187. Epub 2014 Oct 30. Review.
2014
|
| 18 | ABCA1, ABCG1, ABCG4
|
| ABCA1, ABCG1, and ABCG4 are distributed to distinct membrane meso-domains and disturb detergent-resistant domains on the plasma membrane.
|
| Sano O, Ito S, Kato R, Shimizu Y, Kobayashi A, Kimura Y, Kioka N, Hanada K, Ueda K, Matsuo M.
|
| PLoS One 9(10):e109886. doi: 10.1371/journal.pone.0109886. eCollection 2014.
2014
|
| 19 | ABCA1, ELAVL1
|
| RNA binding protein HuR regulates the expression of ABCA1.
|
| Ramírez CM, Lin CS, Abdelmohsen K, Goedeke L, Yoon JH, Madrigal-Matute J, Martin-Ventura JL, Vo DT, Uren PJ, Penalva LO, Gorospe M, Fernández-Hernando C.
|
| J Lipid Res 55(6):1066-76. doi: 10.1194/jlr.M044925. Epub 2014 Apr 11.
2014
|
| 20 | ABCA1, AFAP1, GMDS
|
| Common variants near ABCA1, AFAP1 and GMDS confer risk of primary open-angle glaucoma.
|
| Gharahkhani P, Burdon KP, Fogarty R, Sharma S, Hewitt AW, Martin S, Law MH, Cremin K, Bailey JNC, Loomis SJ, Pasquale LR, Haines JL, Hauser MA, Viswanathan AC, McGuffin P, Topouzis F, Foster PJ, Graham SL, Casson RJ, Chehade M, White AJ, Zhou T, Souzeau E, Landers J, Fitzgerald JT, Klebe S, Ruddle JB, Goldberg I, Healey PR; Wellcome Trust Case Control Consortium 2, NEIGHBORHOOD consortium, Mills RA, Wang JJ, Montgomery GW, Martin NG, RadfordSmith G, Whiteman DC, Brown MA, Wiggs JL, Mackey DA, Mitchell P, MacGregor S, Craig JE.
|
| Nat Genet. Oct;46(10):1120-1125. doi: 10.1038/ng.3079. Epub 2014 Aug 31 2014
|
| 21 | ABCA1, ARFGEF1
|
| BIG1, a brefeldin A-inhibited guanine nucleotide-exchange protein modulates ATP-binding cassette transporter A-1 trafficking and function.
|
| Lin S, Zhou C, Neufeld E, Wang YH, Xu SW, Lu L, Wang Y, Liu ZP, Li D, Li C, Chen S, Le K, Huang H, Liu P, Moss J, Vaughan M, Shen X.
|
| Arterioscler Thromb Vasc Biol 33(2):e31-8. doi: 10.1161/ATVBAHA.112.300720. Epub 2012 Dec 6.
2013
|
| 22 | ABCA1, PLD2, PRKCH, TLR2
|
| TLR2 stimulates ABCA1 expression via PKC-η and PLD2 pathway.
|
| Park DW, Lee HK, Lyu JH, Chin H, Kang SW, Kim YJ, Bae YS, Baek SH.
|
| Biochem Biophys Res Commun 430(3):933-7. doi: 10.1016/j.bbrc.2012.11.135. Epub 2012 Dec 19.
2013
|
| 23 | ABCA1, ABCG5, ABCG8
|
| ATP-binding cassette sterol transporters are differentially expressed in normal and diseased human gallbladder.
|
| Yoon JH, Choi HS, Jun DW, Yoo KS, Lee J, Yang SY, Kuver R.
|
| Dig Dis Sci 58(2):431-9. doi: 10.1007/s10620-012-2481-0. Epub 2012 Nov 22.
2013
|
| 24 | ABCA1, NPC1, NPC2
|
| ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
|
| Boadu E, Nelson RC, Francis GA.
|
| Biochim Biophys Acta 1821(3):396-404. doi: 10.1016/j.bbalip.2011.11.013. Epub 2011 Dec 10.
2012
|
| 25 | ABCA1, ABCG1
|
| Loss of both ABCA1 and ABCG1 results in increased disturbances in islet sterol homeostasis, inflammation, and impaired β-cell function.
|
| Kruit JK, Wijesekara N, Westwell-Roper C, Vanmierlo T, de Haan W, Bhattacharjee A, Tang R, Wellington CL, LütJohann D, Johnson JD, Brunham LR, Verchere CB, Hayden MR.
|
| Diabetes 61(3):659-64. doi: 10.2337/db11-1341. Epub 2012 Feb 7.
2012
|
| 26 | ABCA1, IL10, PRKACA
|
| ABCA1 protein enhances Toll-like receptor 4 (TLR4)-stimulated interleukin-10 (IL-10) secretion through protein kinase A (PKA) activation.
|
| Ma L, Dong F, Zaid M, Kumar A, Zha X.
|
| J Biol Chem 287(48):40502-12. doi: 10.1074/jbc.M112.413245. Epub 2012 Oct 10.
2012
|
| 27 | ABCA1, NR1H2
|
| Liver X receptor beta (LXRbeta) interacts directly with ATP-binding cassette A1 (ABCA1) to promote high density lipoprotein formation during acute cholesterol accumulation.
|
| Hozoji-Inada M, Munehira Y, Nagao K, Kioka N, Ueda K.
|
| J Biol Chem 286(22):20117-24. Epub 2011 Apr 20.
2011
|
| 28 | ABCA1, LIPC
|
| Association of variants in the LIPC and ABCA1 genes with intermediate and large drusen and advanced age-related macular degeneration.
|
| Yu Y, Reynolds R, Fagerness J, Rosner B, Daly MJ, Seddon JM.
|
| Invest Ophthalmol Vis Sci. 52(7):4663-70. 2011
|
| 29 | ABCA1, APOE
|
| A novel function of apolipoprotein E: upregulation of ATP-binding cassette transporter A1 expression.
|
| Zhao Y, Chen X, Yang H, Zhou L, Okoro EU, Guo Z.
|
| PLoS One 6(7):e21453. doi: 10.1371/journal.pone.0021453. Epub 2011 Jul 11.
2011
|
| 30 | ABCA1, LIPA, LIPAD
|
| Lysosomal acid lipase deficiency impairs regulation of ABCA1 gene and formation of high density lipoproteins in cholesteryl ester storage disease.
|
| Bowden KL, Bilbey NJ, Bilawchuk LM, Boadu E, Sidhu R, Ory DS, Du H, Chan T, Francis GA.
|
| J Biol Chem 286(35):30624-35. doi: 10.1074/jbc.M111.274381. Epub 2011 Jul 10.
2011
|
| 31 | ABCA1, ABCA3
|
| Expression of the lipid transporters ABCA3 and ABCA1 is diminished in human breast cancer tissue.
|
| Schimanski S, Wild PJ, Treeck O, Horn F, Sigruener A, Rudolph C, Blaszyk H, Klinkhammer-Schalke M, Ortmann O, Hartmann A, Schmitz G.
|
| Horm Metab Res 42(2):102-9. Epub 2009 Nov 9.
2010
|
| 32 | ABCA1
|
| Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.
|
| Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML.
|
| Biochemistry 49(38):8338-49.
2010
|
| 33 | ABCA1
|
| ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.
|
| Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR.
|
| Science. 328(5986):1689-93. 2010
|
| 34 | ABCA1, ABCG1
|
| ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.
|
| Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR.
|
| Science 328(5986):1689-93. doi: 10.1126/science.1189731. Epub 2010 May 20.
2010
|
| 35 | ABCA1
|
| ABCA1 modulates the oligomerization and Golgi exit of caveolin-1 during HDL-mediated cholesterol efflux in aortic endothelial cells.
|
| Lin YC, Lin CH, Kuo CY, Yang VC.
|
| Biochem Biophys Res Commun 382(1):189-95. Epub 2009 Mar 9.
2009
|
| 36 | ABCA1
|
| The COP9 signalosome controls ubiquitinylation of ABCA1.
|
| Azuma Y, Takada M, Maeda M, Kioka N, Ueda K.
|
| Biochem Biophys Res Commun. 382(1):145-8. 2009
|
| 37 | ABCA1, ABCG5, ABCG8, ABLP, APOB, APOB, APOC2, ARH, FDB, FHBL1, HCHOLA3, HDLDT1, LDLR, LDLRAP1, LIPAD, LPL, MTTP, PBAM, PCSK9, SLC10A2, STSL
|
| Monogenic pediatric dyslipidemias: classification, genetics and clinical spectrum.
|
| Rahalkar AR, Hegele RA.
|
| Mol Genet Metab 93(3):282-94. Epub 2007 Nov 26. Review. 2008
|
| 38 | ABCA1, SLOS
|
| Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.
|
| Lindegaard ML, Wassif CA, Vaisman B, Amar M, Wasmuth EV, Shamburek R, Nielsen LB, Remaley AT, Porter FD.
|
| Hum Mol Genet 17(23):3806-13. Epub 2008 Sep 5.
2008
|
| 39 | ABCA1, SPTLC1
|
| SPTLC1 binds ABCA1 to negatively regulate trafficking and cholesterol efflux activity of the transporter.
|
| Tamehiro N, Zhou S, Okuhira K, Benita Y, Brown CE, Zhuang DZ, Latz E, Hornemann T, von Eckardstein A, Xavier RJ, Freeman MW, Fitzgerald ML.
|
| Biochemistry 47(23):6138-47. Epub 2008 May 17.PMID: 18484747 2008
|
| 40 | ABCA1, ABCA7
|
| ATP-binding cassette transporters ABCA1, ABCA7, and ABCG1 in mouse spermatozoa.
|
| Morales CR, Marat AL, Ni X, Yu Y, Oko R, Smith BT, Argraves WS.
|
| Biochem Biophys Res Commun 376(3):472-7. Epub 2008 Sep 13.
2008
|
| 41 | ABCA1
|
| Functional polymorphism in ABCA1 influences age of symptom onset in coronary artery disease patients.
|
| Kyriakou T, Pontefract DE, Viturro E, Hodgkinson CP, Laxton RC, Bogari N, Cooper G, Davies M, Giblett J, Day IN, Simpson IA, Albrecht C, Ye S.
|
| Hum Mol Genet 16(12):1412-22. Epub 2007 Apr 5. 2007
|
| 42 | ABCA1
|
| Association of genetic variants of ABCA1 with Alzheimer's disease risk.
|
| Rodr’guez-Rodr’guez E, Mateo I, Llorca J, S‡nchez-Quintana C, Infante J, Garc’a-Gorostiaga I, S‡nchez-Juan P, Berciano J, Combarros O.
|
| Am J Med Genet B Neuropsychiatr Genet 144(7):964-8. 2007
|
| 43 | ABCA1,PDGFA
|
| Platelet derived growth factor regulates ABCA1 expression in vascular smooth muscle cells.
|
| Nagao S, Murao K, Imachi H, Cao WM, Yu X, Li J, Matsumoto K, Nishiuchi T, Ahmed RA, Wong NC, Ueda K, Ishida T.
|
| FEBS Lett 580(18):4371-6. Epub 2006 Jul 10. 2006
|
| 44 | ABCA1, ABCG1, ABCG4
|
| ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL.
|
| Vaughan AM, Oram JF.
|
| J Lipid Res 47(11):2433-43. Epub 2006 Aug 10. 2006
|
| 45 | ABCA1, MEGF10
|
| Cooperation between engulfment receptors: the case of ABCA1 and MEGF10.
|
| Hamon Y, Trompier D, Ma Z, Venegas V, Pophillat M, Mignotte V, Zhou Z, Chimini G.
|
| PLoS One 1:e120.PMID: 17205124 2006
|
| 46 | ABCA1, ABCG1
|
| Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.
|
| Kobayashi A, Takanezawa Y, Hirata T, Shimizu Y, Misasa K, Kioka N, Arai H, Ueda K, Matsuo M.
|
| J Lipid Res. 47(8):1791-802. 2006
|
| 47 | CETP, ABCA1, LPL, APOC3, APOA4
|
| Genetic determinants of plasma HDL-cholesterol levels in familial hypercholesterolemia.
|
| van Aalst-Cohen ES, Jansen AC, Boekholdt SM, Tanck MW, Fontecha MR, Cheng S, Li J, Defesche JC, Kuivenhoven JA, Kastelein JJ.
|
| Eur J Hum Genet 13(10):1137-42. 2005
|
| 48 | ABCA1
|
| A PEST deletion mutant of ABCA1 shows impaired internalization and defective cholesterol efflux from late endosomes.
|
| Chen W, Wang N, Tall AR.
|
| J Biol Chem 280(32):29277-81. Epub 2005 Jun 10. 2005
|
| 49 | ABCA1, HDLDT1
|
| Genotypic effect of the -565C>T polymorphism in the ABCA1 gene promoter on ABCA1 expression and severity of atherosclerosis.
|
| Kyriakou T, Hodgkinson C, Pontefract DE, Iyengar S, Howell WM, Wong YK, Eriksson P, Ye S.
|
| Arterioscler Thromb Vasc Biol 25(2):418-23. Epub 2004 Nov 4. 2005
|
| 50 | ABCA1, PLIN1
|
| Genes of cholesterol metabolism in human atheroma: overexpression of perilipin and genes promoting cholesterol storage and repression of ABCA1 expression.
|
| Forcheron F, Legedz L, Chinetti G, Feugier P, Letexier D, Bricca G, Beylot M.
|
| Arterioscler Thromb Vasc Biol 25(8):1711-7. Epub 2005 Jun 16. 2005
|
| 51 | ABCA1, ABCA7
|
| Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7.
|
| Hayashi M, Abe-Dohmae S, Okazaki M, Ueda K, Yokoyama S.
|
| J Lipid Res 46(8):1703-11. Epub 2005 Jun 1.
2005
|
| 52 | ABCA1
|
| Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.
|
| Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW.
|
| J Biol Chem. 280(47):39653-64. 2005
|
| 53 | ABCA1
|
| The ATP-binding cassette transporter 1 mediates lipid efflux from Sertoli cells and influences male fertility.
|
| Selva DM, Hirsch-Reinshagen V, Burgess B, Zhou S, Chan J, McIsaac S, Hayden MR, Hammond GL, Vogl AW, Wellington CL.
|
| J Lipid Res 45(6):1040-50. Epub 2004 Mar 16. 2004
|
| 54 | HDLD, ABCA1
|
| Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency.
|
| Albrecht C, Baynes K, Sardini A, Schepelmann S, Eden ER, Davies SW, Higgins CF, Feher MD, Owen JS, Soutar AK.
|
| Biochim Biophys Acta 1689(1):47-57. 2004
|
| 55 | ABCA1, SREBF2
|
| Sterol-responsive element-binding protein (SREBP) 2 down-regulates ATP-binding cassette transporter A1 in vascular endothelial cells: a novel role of SREBP in regulating cholesterol metabolism.
|
| Zeng L, Liao H, Liu Y, Lee TS, Zhu M, Wang X, Stemerman MB, Zhu Y, Shyy JY.
|
| J Biol Chem 279(47):48801-7. Epub 2004 Sep 8. 2004
|
| 56 | ABCA1
|
| Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter.
|
| Roosbeek S, Peelman F, Verhee A, Labeur C, Caster H, Lensink MF, Cirulli C, Grooten J, Cochet C, Vandekerckhove J, Amoresano A, Chimini G, Tavernier J, Rosseneu M.
|
| J Biol Chem. 279(36):37779-88. 2004
|
| 57 | ABCA1
|
| Alpha1-syntrophin modulates turnover of ABCA1.
|
| Munehira Y, Ohnishi T, Kawamoto S, Furuya A, Shitara K, Imamura M, Yokota T, Takeda S, Amachi T, Matsuo M, Kioka N, Ueda K.
|
| J Biol Chem. 279(15):15091-5. 2004
|
| 58 | ABCA1
|
| Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
|
| Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G.
|
| Mol Biol Cell. 15(12):5399-407. 2004
|
| 59 | ABCA1
|
| Impaired platelet activation in familial high density lipoprotein deficiency (Tangier disease).
|
| Nofer JR, Herminghaus G, Brodde M, Morgenstern E, Rust S, Engel T, Seedorf U, Assmann G, Bluethmann H, Kehrel BE.
|
| J Biol Chem. 279(32):34032-7. 2004
|
| 60 | ABCA1
|
| Deficiency of ABCA1 impairs apolipoprotein E metabolism in brain.
|
| Hirsch-Reinshagen V, Zhou S, Burgess BL, Bernier L, McIsaac SA, Chan JY, Tansley GH, Cohn JS, Hayden MR, Wellington CL.
|
| J Biol Chem. 279(39):41197-207. 2004
|
| 61 | ABCA1
|
| ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.
|
| Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, Kowalewski T, Holtzman DM.
|
| J Biol Chem. 279(39):40987-93. 2004
|
| 62 | ABCA1, FLOT1, STX12
|
| Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells.
|
| Bared SM, Buechler C, Boettcher A, Dayoub R, Sigruener A, Grandl M, Rudolph C, Dada A, Schmitz G.
|
| Mol Biol Cell 15(12):5399-407. Epub 2004 Oct 6.
2004
|
| 63 | ABCA1
|
| A common variant in the ABCA1 gene is associated with a lower risk for premature coronary heart disease in familial hypercholesterolaemia.
|
| Cenarro A, Artieda M, Castillo S, Mozas P, Reyes G, Tejedor D, Alonso R, Mata P, Pocovi M, Civeira F.
|
| J Med Genet 40(3):163-8. 2003
|
| 64 | ABCA1
|
| ABCA1 gene polymorphisms and their associations with coronary artery disease and plasma lipids in males from three ethnic populations in Singapore.
|
| Tan JH, Low PS, Tan YS, Tong MC, Saha N, Yang H, Heng CK.
|
| Hum Genet 113(2):106-17. Epub 2003 Apr 23. 2003
|
| 65 | ABCA7, ABCA1
|
| ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux.
|
| Wang N, Lan D, Gerbod-Giannone M, Linsel-Nitschke P, Jehle AW, Chen W, Martinez LO, Tall AR.
|
| J Biol Chem 278(44):42906-12. Epub 2003 Aug 12. 2003
|
| 66 | ABCA1
|
| Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells.
|
| Oram JF, Wolfbauer G, Vaughan AM, Tang C, Albers JJ.
|
| J Biol Chem. 278(52):52379-85. 2003
|
| 67 | ABCA1
|
| ABCA1 regulatory variants influence coronary artery disease independent of effects on plasma lipid levels.
|
| Zwarts KY, Clee SM, Zwinderman AH, Engert JC, Singaraja R, Loubser O, James E, Roomp K, Hudson TJ, Jukema JW, Kastelein JJ, Hayden MR.
|
| Clin Genet 61(2):115-25. 2002
|
| 68 | ABCA1
|
| Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.
|
| van Eck M, Bos IS, Kaminski WE, Orso E, Rothe G, Twisk J, Bottcher A, Van Amersfoort ES, Christiansen-Weber TA, Fung-Leung WP, Van Berkel TJ, Schmitz G.
|
| Proc Natl Acad Sci U S A 99(9):6298-303. 2002
|
| 69 | ABCA1, HDLD
|
| Expression and functional analyses of novel mutations of ATP-binding cassette transporter-1 in Japanese patients with high-density lipoprotein deficiency.
|
| Nishida Y, Hirano K, Tsukamoto K, Nagano M, Ikegami C, Roomp K, Ishihara M, Sakane N, Zhang Z, Tsujii Ki K, Matsuyama A, Ohama T, Matsuura F, Ishigami M, Sakai N, Hiraoka H, Hattori H, Wellington C, Yoshida Y, Misugi S, Hayden MR, Egashira T, Yamashita S, Matsuzawa Y.
|
| Biochem Biophys Res Commun 290(2):713-21. 2002
|
| 70 | ABCA1, HDLDT1
|
| Double deletions and missense mutations in the first nucleotide-binding fold of the ATP-binding cassette transporter A1 ( ABCA1) gene in Japanese patients with Tangier disease.
|
| Guo Z, Inazu A, Yu W, Suzumura T, Okamoto M, Nohara A, Higashikata T, Sano R, Wakasugi K, Hayakawa T, Yoshida K, Suehiro T, Schmitz G, Mabuchi H.
|
| J Hum Genet 47(6):325-9. 2002
|
| 71 | ABCA1
|
| Increased ABCA1 activity protects against atherosclerosis.
|
| Singaraja RR, Fievet C, Castro G, James ER, Hennuyer N, Clee SM, Bissada N, Choy JC, Fruchart JC, McManus BM, Staels B, Hayden MR.
|
| J Clin Invest 110(1):35-42. 2002
|
| 72 | FADD, ABCA1
|
| Molecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein.
|
| Buechler C, Bared SM, Aslanidis C, Ritter M, Drobnik W, Schmitz G.
|
| J Biol Chem 277(44):41307-10. Epub 2002 Sep 13. 2002
|
| 73 | ABCA1
|
| Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.
|
| Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW.
|
| J Biol Chem. 277(36):33178-87. 2002
|
| 74 | ABCA1
|
| The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.
|
| Buechler C, Boettcher A, Bared SM, Probst MC, Schmitz G.
|
| Biochem Biophys Res Commun. 293(2):759-65. 2002
|
| 75 | ABCA1
|
| Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences.
|
| Qiu Y, Cavelier L, Chiu S, Yang X, Rubin E, Cheng JF.
|
| Genomics 73(1):66-76. 2001
|
| 76 | ABCA1
|
| Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease.
|
| Clee SM, Zwinderman AH, Engert JC, Zwarts KY, Molhuizen HO, Roomp K, Jukema JW, van Wijland M, van Dam M, Hudson TJ, Brooks-Wilson A, Genest J Jr, Kastelein JJ, Hayden MR.
|
| Circulation 103(9):1198-205. 2001
|
| 77 | ABCA1
|
| Identification of an alternative transcript of ABCA1 gene in different human cell types.
|
| Bellincampi L, Simone ML, Motti C, Cortese C, Bernardini S, Bertolini S, Calandra S.
|
| Biochem Biophys Res Commun 283(3):590-7. 2001
|
| 78 | ABCA1
|
| Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjogren's Syndrome.
|
| Tanaka AR, Ikeda Y, Abe-Dohmae S, Arakawa R, Sadanami K, Kidera A, Nakagawa S, Nagase T, Aoki R, Kioka N, Amachi T, Yokoyama S, Ueda K.
|
| Biochem Biophys Res Commun 283(5):1019-25. 2001
|
| 79 | ABCA1
|
| ATP-binding cassette transporter A1 (ABCA1) functions as a cholesterol efflux regulatory protein.
|
| Wang N, Silver DL, Thiele C, Tall AR.
|
| J Biol Chem 276(26):23742-7. 2001
|
| 80 | ABCA1
|
| Characterization of the ATPase cycle of human ABCA1: implications for its function as a regulator rather than an active transporter
|
| Szakacs G, Langmann T, Ozvegy C, Orso E, Schmitz G, Varadi A, Sarkadi B.
|
| Biochem Biophys Res Commun 288(5):1258-64. 2001
|
| 81 | ABCA1
|
| Complete genomic sequence of the human ABCA1 gene: analysis of the human and mouse ATP-binding cassette A promoter.
|
| Santamarina-Fojo S, Peterson K, Knapper C, Qiu Y, Freeman L, Cheng JF, Osorio J, Remaley A, Yang XP, Haudenschild C, Prades C, Chimini G, Blackmon E, Francois T, Duverger N, Rubin EM, Rosier M, Denefle P, Fredrickson DS, Brewer HB Jr.
|
| Proc Natl Acad Sci U S A 97(14):7987-92. 2000
|
| 82 | ABCA1, ABCB11, NR0B2, NR1H3, NR1H4, NR5A2, SCARB1, SLC10A1, SCARB1
|
| Don't know much bile-ology.
|
| Chawla A, Saez E, Evans RM.
|
| Cell 103(1):1-4. No abstract available. 2000
|
| 83 | ABCA1
|
| Analysis of hABC1 gene 5' end: additional peptide sequence, promoter region, and four polymorphisms.
|
| Pullinger CR, Hakamata H, Duchateau PN, Eng C, Aouizerat BE, Cho MH, Fielding CJ, Kane JP.
|
| Biochem Biophys Res Commun 271(2):451-5. 2000
|
| 84 | ABCA1
|
| Transport of lipids from golgi to plasma membrane is defective in tangier disease patients and Abc1-deficient mice.
|
| Orsó E, Broccardo C, Kaminski WE, Böttcher A, Liebisch G, Drobnik W, Götz A, Chambenoit O, Diederich W, Langmann T, Spruss T, Luciani MF, Rothe G, Lackner KJ, Chimini G, Schmitz G.
|
| Nat Genet. 24(2):192-6. 2000
|
| 85 | ABCA1
|
| High density lipoprotein deficiency and foam cell accumulation in mice with targeted disruption of ATP-binding cassette transporter-1.
|
| McNeish J, Aiello RJ, Guyot D, Turi T, Gabel C, Aldinger C, Hoppe KL, Roach ML, Royer LJ, de Wet J, Broccardo C, Chimini G, Francone OL.
|
| Proc Natl Acad Sci U S A. 97(8):4245-50. 2000
|
| 86 | ABCA1, HDLDT1, HDLD
|
| Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency.
|
| Brooks-Wilson A, et al.
|
| Nat Genet 22(4):336-45. 1999
|
| 87 | ABCA1, HDLDT1
|
| The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease.
|
| Bodzioch M, et al.
|
| Nat Genet 22(4):347-51. 1999
|
| 88 | HDLDT1, ABCA1
|
| Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1.
|
| Rust S, et al.
|
| Nat Genet 22(4):352-5. 1999
|
| 89 | ABCA1, HDLDT1
|
| Human ATP-binding cassette transporter 1 (ABC1): genomic organization and identification of the genetic defect in the original tangier disease kindred.
|
| Remaley AT, et al.
|
| Proc Natl Acad Sci U S A 96(22):12685-90 1999
|
| 90 | ABCA1
|
| The Tangier disease gene product ABC1 controls the cellular apolipoprotein-mediated lipid removal pathway.
|
| Lawn RM, Wade DP, Garvin MR, Wang X, Schwartz K, Porter JG, Seilhamer JJ, Vaughan AM, Oram JF.
|
| J Clin Invest. 104(8):R25-31. 1999
|
| 91 | ABCA1
|
| Molecular cloning of the human ATP-binding cassette transporter 1 (hABC1): evidence for sterol-dependent regulation in macrophages.
|
| Langmann T, Klucken J, Reil M, Liebisch G, Luciani MF, Chimini G, Kaminski WE, Schmitz G.
|
| Biochem Biophys Res Commun. 257(1):29-33. 1999
|
| 92 | ABCA1, ABCA2, ABCA3
|
| Cloning of two novel ABC transporters mapping on human chromosome 9.
|
| Luciani MF, et al.
|
| Genomics 21 : 150-159. 1994
|