Citations for
1AATF
Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.
Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M.
Cell Death Dis 6:e1764. doi: 10.1038/cddis.2015.117. 2015
2AATF
Discovering Che-1/AATF: a new attractive target for cancer therapy.
Iezzi S, Fanciulli M.
Front Genet 6:141. doi: 10.3389/fgene.2015.00141. eCollection 2015. Review. 2015
3AATF, HIPK2
HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation.
De Nicola F, Catena V, Rinaldo C, Bruno T, Iezzi S, Sorino C, Desantis A, Camerini S, Crescenzi M, Floridi A, Passananti C, Soddu S, Fanciulli M.
Cell Death Dis 5:e1414. doi: 10.1038/cddis.2014.381. 2014
4AATF, PPP1R7, PPP2R5D, TADA3
Identification of transcriptional and phosphatase regulators as interaction partners of human ADA3, a component of histone acetyltransferase complexes.
Zencir S, Sike A, Dobson MJ, Ayaydin F, Boros I, Topcu Z.
Biochem J 450(2):311-20. doi: 10.1042/BJ20120452. 2013
5AATF
Apoptosis-antagonizing transcription factor (AATF) gene silencing: role in induction of apoptosis and down-regulation of estrogen receptor in breast cancer cells.
Sharma M.
Biotechnol Lett 35(10):1561-70. doi: 10.1007/s10529-013-1257-8. Epub 2013 Jun 26. 2013
6AATF
Centrosomal Che-1 protein is involved in the regulation of mitosis and DNA damage response by mediating pericentrin (PCNT)-dependent Chk1 protein localization.
Sorino C, Bruno T, Desantis A, Di Certo MG, Iezzi S, De Nicola F, Catena V, Floridi A, Chessa L, Passananti C, Cundari E, Fanciulli M.
J Biol Chem 288(32):23348-57. doi: 10.1074/jbc.M113.465302. Epub 2013 Jun 24. 2013
7AATF, JUN
Nucleolar AATF regulates c-Jun-mediated apoptosis.
Ferraris SE, Isoniemi K, Torvaldson E, Anckar J, Westermarck J, Eriksson JE.
Mol Biol Cell 23(21):4323-32. doi: 10.1091/mbc.E12-05-0419. Epub 2012 Aug 29. 2012
8AATF
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T.
EMBO J 31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21. 2012
9AATF
Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.
Bruno T, Desantis A, Bossi G, Di Agostino S, Sorino C, De Nicola F, Iezzi S, Franchitto A, Benassi B, Galanti S, La Rosa F, Floridi A, Bellacosa A, Passananti C, Blandino G, Fanciulli M.
Cancer Cell 18(2):122-34. doi: 10.1016/j.ccr.2010.05.027. 2010
10AATF, WFS1
AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1.
Ishigaki S, Fonseca SG, Oslowski CM, Jurczyk A, Shearstone JR, Zhu LJ, Permutt MA, Greiner DL, Bortell R, Urano F.
Cell Death Differ 17(5):774-86. doi: 10.1038/cdd.2009.175. Epub 2009 Nov 13. 2010
11AATF, XIAP
Che-1 activates XIAP expression in response to DNA damage.
Bruno T, Iezzi S, De Nicola F, Di Padova M, Desantis A, Scarsella M, Di Certo MG, Leonetti C, Floridi A, Passananti C, Fanciulli M.
Cell Death Differ 15(3):515-20. Epub 2007 Nov 30. 2008
12AATF
The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage.
De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi A, Passananti C, Del Sal G, Fanciulli M.
J Biol Chem 282(27):19685-91. Epub 2007 Apr 27. 2007
13AATF
Functional characterization of AATF transcriptome in human leukemic cells.
Kaul D, Mehrotra A.
Mol Cell Biochem 297(1-2):215-20. Epub 2006 Sep 28. 2007
14AATF
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Bruno T, De Nicola F, Iezzi S, Lecis D, D'Angelo C, Di Padova M, Corbi N, Dimiziani L, Zannini L, Jekimovs C, Scarsella M, Porrello A, Chersi A, Crescenzi M, Leonetti C, Khanna KK, Soddu S, Floridi A, Passananti C, Delia D, Fanciulli M.
Cancer Cell 10(6):473-86. 2006
15TSG101, AATF
TSG101 interacts with apoptosis-antagonizing transcription factor and enhances androgen receptor-mediated transcription by promoting its monoubiquitination.
Burgdorf S, Leister P, Scheidtmann KH.
J Biol Chem 279(17):17524-34. Epub 2004 Feb 2. 2004
16AATF, CDKN1A, HDAC1
Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter.
Di Padova M, Bruno T, De Nicola F, Iezzi S, D'Angelo C, Gallo R, Nicosia D, Corbi N, Biroccio A, Floridi A, Passananti C, Fanciulli M.
J Biol Chem 278(38):36496-504. Epub 2003 Jul 7. 2003
17AATF
Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis.
Barbato C, Corbi N, Canu N, Fanciulli M, Serafino A, Ciotti M, Libri V, Bruno T, Amadoro G, De Angelis R, Calissano P, Passananti C.
Mol Cell Neurosci 24(4):1038-50. 2003
18AATF
Identification of novel transcription factor-like gene from human intestinal cells.
Lindfors K, Halttunen T, Huotari P, Nupponen N, Vihinen M, Visakorpi T, Maki M, Kainulainen H.
Biochem Biophys Res Commun 276(2):660-6. 2000
19AATF
AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis.
Page G, Lodige I, Kogel D, Scheidtmann KH.
FEBS Lett 462(1-2):187-91. 1999