1 | NR4A1, WT1
|
| The stress-response molecule NR4A1 resists ROS-induced pancreatic β-cells apoptosis via WT1.
|
| Zong C, Qin D, Yu C, Gao P, Chen J, Lu S, Zhang Y, Liu Y, Yang Y, Pu Z, Li X, Fu Y, Guan Q, Wang X.
|
| Cell Signal 35:129-139. doi: 10.1016/j.cellsig.2017.03.012. [Epub ahead of print]
2017
|
2 | MAGI2, WT1
|
| Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.
|
| Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas-Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, Schedl A.
|
| Kidney Int 88(2):321-31. doi: 10.1038/ki.2015.140. Epub 2015 May 20.
2015
|
3 | ABCB1, EPS8, WT1
|
| Overexpression of EPS8 is associated with poor prognosis in patients with acute lymphoblastic leukemia.
|
| He YZ, Liang Z, Wu MR, Wen Q, Deng L, Song CY, Wu BY, Tu SF, Huang R, Li YH.
|
| Leuk Res. Jun;39(6):575-81. doi: 10.1016/j.leukres.2015.03.007. Epub 2015 Mar 20. 2015
|
4 | MAD2L1, WT1
|
| WT1 interacts with MAD2 and regulates mitotic checkpoint function.
|
| Shandilya J, Toska E, Richard DJ, Medler KF, Roberts SG.
|
| Nat Commun 5:4903. doi: 10.1038/ncomms5903.
2014
|
5 | WT1, ZNF224
|
| Role of WT1-ZNF224 interaction in the expression of apoptosis- regulating genes.
|
| Montano G, Cesaro E, Fattore L, Vidovic K, Palladino C, Crescitelli R, Izzo P, Turco MC, Costanzo P.
|
| Hum Mol Genet um Mol Genet. 2013 Jan 28. [Epub ahead of print]
2013
|
6 | WT1
|
| The Wilms Tumor Gene, Wt1, Maintains Testicular Cord Integrity by Regulating the Expression of Col4a1 and Col4a2.
|
| Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX.
|
| Biol Reprod iol Reprod. 2013 Jan 16. [Epub ahead of print]
2013
|
7 | WT1
|
| The Wilms' tumor gene (WT1) regulates E-cadherin expression and migration of prostate cancer cells.
|
| Brett A, Pandey S, Fraizer G.
|
| Mol Cancer 12(1):3. [Epub ahead of print] 2013
|
8 | USP18, WT1
|
| Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target.
|
| Shahidul Makki M, Cristy Ruteshouser E, Huff V.
|
| Exp Cell Res xp Cell Res. 2013 Jan 2. doi:pii: S0014-4827(12)00498-3. 10.1016/j.yexcr.2012.12.021. [Epub ahead of print]
2013
|
9 | DEL9Q22, PTCH1, WT1
|
| Wilms' tumor in patients with 9q22.3 microdeletion syndrome suggests a role for PTCH1 in nephroblastomas.
|
| Isidor B, Bourdeaut F, Lafon D, Plessis G, Lacaze E, Kannengiesser C, Rossignol S, Pichon O, Briand A, Martin-Coignard D, Piccione M, David A, Delattre O, Jeanpierre C, Sévenet N, Le Caignec C.
|
| Eur J Hum Genet ur J Hum Genet. 2012 Nov 21. doi: 10.1038/ejhg.2012.252. [Epub ahead of print] 2012
|
10 | SOX11, WNT4, WT1
|
| WT1 and Sox11 regulate synergistically the promoter of the Wnt4 gene that encodes a critical signal for nephrogenesis.
|
| Murugan S, Shan J, Kühl SJ, Tata A, Pietilä I, Kühl M, Vainio SJ.
|
| Exp Cell Res 318(10):1134-45. doi: 10.1016/j.yexcr.2012.03.008. Epub 2012 Mar 17.
2012
|
11 | IDMS, WT1
|
| Focal segmental glomerulosclerosis in patients with complete deletion of one WT1 allele.
|
| Iijima K, Someya T, Ito S, Nozu K, Nakanishi K, Matsuoka K, Ohashi H, Nagata M, Kamei K, Sasaki S.
|
| Pediatrics 129(6):e1621-5. doi: 10.1542/peds.2011-1323. Epub 2012 May 14.
2012
|
12 | WT1
|
| Nuclear transport of Wilms' tumour protein Wt1 involves importins α and β.
|
| Depping R, Schindler SG, Jacobi C, Kirschner KM, Scholz H.
|
| Cell Physiol Biochem 29(1-2):223-32. doi: 10.1159/000337603. Epub 2012 Mar 1.
2012
|
13 | WT1
|
| Abnormal WT1 expression in human fetuses with bilateral renal agenesis and cardiac malformations.
|
| Loo CK, Pereira TN, Ramm GA.
|
| Birth Defects Res A Clin Mol Teratol 94(2):116-22. doi: 10.1002/bdra.22881. Epub 2012 Jan 13.
2012
|
14 | BASP1, INPP5J, WT1
|
| Repression of transcription by WT1-BASP1 requires the myristoylation of BASP1 and the PIP2-dependent recruitment of histone deacetylase.
|
| Toska E, Campbell HA, Shandilya J, Goodfellow SJ, Shore P, Medler KF, Roberts SG.
|
| Cell Rep 2(3):462-9. doi: 10.1016/j.celrep.2012.08.005. Epub 2012 Aug 30. 2012
|
15 | WT1
|
| Common variants at 11p13 are associated with susceptibility to tuberculosis.
|
| Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewski F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff TH, Hill AV, Horstmann RD, Meyer CG.
|
| Nat Genet 44(3):257-9. doi: 10.1038/ng.1080.
2012
|
16 | EYA1, NR2F2, WT1
|
| COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival.
|
| Yu CT, Tang K, Suh JM, Jiang R, Tsai SY, Tsai MJ.
|
| Development 139(13):2330-9. doi: 10.1242/dev.076299.
2012
|
17 | MEN1, PAX2, WT1
|
| Tumor suppressor menin represses paired box gene 2 expression via Wilms tumor suppressor protein-polycomb group complex.
|
| Xu B, Zeng DQ, Wu Y, Zheng R, Gu L, Lin X, Hua X, Jin GH.
|
| J Biol Chem 286(16):13937-44. Epub 2011 Mar 4.
2011
|
18 | WT1
|
| WT1 regulates epicardial epithelial to mesenchymal transition through β-catenin and retinoic acid signaling pathways.
|
| von Gise A, Zhou B, Honor LB, Ma Q, Petryk A, Pu WT.
|
| Dev Biol 356(2):421-31. Epub 2011 May 30.
2011
|
19 | SRPK1, WT1
|
| WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.
|
| Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR.
|
| Cancer Cell 20(6):768-80. doi: 10.1016/j.ccr.2011.10.016.
2011
|
20 | WT1
|
| WT1 protein directly regulates expression of vascular endothelial growth factor and is a mediator of tumor response to hypoxia.
|
| McCarty G, Awad O, Loeb DM.
|
| J Biol Chem 286(51):43634-43. doi: 10.1074/jbc.M111.310128. Epub 2011 Oct 26.
2011
|
21 | WT1
|
| Expression of WT1 during normal human kidney development.
|
| Fanni D, Fanos V, Monga G, Gerosa C, Locci A, Nemolato S, Van Eyken P, Faa G.
|
| J Matern Fetal Neonatal Med 24 Suppl 2:44-7. doi: 10.3109/14767058.2011.606619. Epub 2011 Sep 2.
2011
|
22 | LIMS1, WT1
|
| PINCH1 is transcriptional regulator in podocytes that interacts with WT1 and represses podocalyxin expression.
|
| Wang D, Li Y, Wu C, Liu Y.
|
| PLoS One 6(2):e17048. doi: 10.1371/journal.pone.0017048.
2011
|
23 | ALDH1A2, WT1
|
| Wt1 controls retinoic acid signalling in embryonic epicardium through transcriptional activation of Raldh2.
|
| Guadix JA, Ruiz-Villalba A, Lettice L, Velecela V, Muñoz-Chápuli R, Hastie ND, Pérez-Pomares JM, Martínez-Estrada OM.
|
| Development 138(6):1093-7. doi: 10.1242/dev.044594.
2011
|
24 | BASP1, WT1
|
| WT1 and its transcriptional cofactor BASP1 redirect the differentiation pathway of an established blood cell line.
|
| Goodfellow SJ, Rebello MR, Toska E, Zeef LA, Rudd SG, Medler KF, Roberts SG.
|
| Biochem J 435(1):113-25. doi: 10.1042/BJ20101734.
2011
|
25 | TBX18, WT1
|
| Developmental patterns and characteristics of epicardial cell markers Tbx18 and Wt1 in murine embryonic heart.
|
| Zeng B, Ren XF, Cao F, Zhou XY, Zhang J.
|
| J Biomed Sci 18:67. doi: 10.1186/1423-0127-18-67.
2011
|
26 | IDMS, WT1
|
| A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes.
|
| Ratelade J, Arrondel C, Hamard G, Garbay S, Harvey S, Biebuyck N, Schulz H, Hastie N, Pontoglio M, Gubler MC, Antignac C, Heidet L.
|
| Hum Mol Genet 19(1):1-15. Epub .PMID: 19797313 2010
|
27 | WT1
|
| Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.
|
| Martínez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Muñoz-Chapuli R, Hastie ND.
|
| Nat Genet 42(1):89-93. Epub 2009 Dec 20.PMID: 20023660 2010
|
28 | CXXC5, WT1
|
| A novel Wilms tumor 1 (WT1) target gene negatively regulates the WNT signaling pathway.
|
| Kim MS, Yoon SK, Bollig F, Kitagaki J, Hur W, Whye NJ, Wu YP, Rivera MN, Park JY, Kim HS, Malik K, Bell DW, Englert C, Perantoni AO, Lee SB.
|
| J Biol Chem 285(19):14585-93. Epub 2010 Mar 10. 2010
|
29 | WT1, ZNF224
|
| Biochemical and functional interaction between ZNF224 and ZNF255, two members of the Kruppel-like zinc-finger protein family and WT1 protein isoforms.
|
| Florio F, Cesaro E, Montano G, Izzo P, Miles C, Costanzo P.
|
| Hum Mol Genet 19(18):3544-56. Epub 2010 Jun 30.PMID: 20591825 2010
|
30 | WT1
|
| Wilms' tumor protein Wt1 regulates the Interleukin-10 (IL-10) gene.
|
| Sciesielski LK, Kirschner KM, Scholz H, Persson AB.
|
| FEBS Lett 584(22):4665-71. doi: 10.1016/j.febslet.2010.10.045. Epub 2010 Oct 26.
2010
|
31 | HTRA2, WT1
|
| The Wilms' tumor suppressor protein WT1 is processed by the serine protease HtrA2/Omi.
|
| Hartkamp J, Carpenter B, Roberts SG.
|
| Mol Cell 37(2):159-71. doi: 10.1016/j.molcel.2009.12.023.
2010
|
32 | CITED2, NR5A1, SRY, WT1
|
| The transcription co-factor CITED2 functions during sex determination and early gonad development.
|
| Buaas FW, Val P, Swain A.
|
| Hum Mol Genet 18(16):2989-3001. Epub 2009 May 20.PMID: 19457926 2009
|
33 | BASP1, WT1
|
| Dynamic interaction between WT1 and BASP1 in transcriptional regulation during differentiation.
|
| Green LM, Wagner KJ, Campbell HA, Addison K, Roberts SG.
|
| Nucleic Acids Res 37(2):431-40. doi: 10.1093/nar/gkn955. Epub 2008 Dec 2.
2009
|
34 | WT1
|
| WT1 expression at diagnosis does not predict survival in pediatric AML: a report from the Children's Oncology Group.
|
| Noronha SA, Farrar JE, Alonzo TA, Gerbing RB, Lacayo NJ, Dahl GV, Ravindranath Y, Arceci RJ, Loeb DM.
|
| Pediatr Blood Cancer 53(6):1136-9.PMID: 19618455 2009
|
35 | IDMS, WT1
|
| Membranoproliferative glomerulonephritis associated with a mutation in Wilms' tumour suppressor gene 1.
|
| Bockenhauer D, van't Hoff W, Chernin G, Heeringa SF, Sebire NJ.
|
| Pediatr Nephrol 24(7):1399-401. Epub 2009 Feb 11.PMID: 19205749 2009
|
36 | DDS, WT1, CDH
|
| Denys-Drash syndrome and congenital diaphragmatic hernia: another case with the 1097G > A(Arg366His) mutation.
|
| Antonius T, van Bon B, Eggink A, van der Burgt I, Noordam K, van Heijst A.
|
| Am J Med Genet A 146(4):496-9. 2008
|
37 | AMER1, CTNNB1, WT1
|
| Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors.
|
| Ruteshouser EC, Robinson SM, Huff V.
|
| Genes Chromosomes Cancer 47(6):461-70. 2008
|
38 | WT1
|
| Wilms tumour gene 1 overexpression in bone marrow as a marker for minimal residual disease in acute myeloid leukaemia.
|
| Hämäläinen MM, Kairisto V, Juvonen V, Johansson J, Aurén J, Kohonen K, Remes K, Salmi TT, Helenius H, Pelliniemi TT.
|
| Eur J Haematol 80(3):201-7. Epub 2007 Dec 10.PMID: 18081724 2008
|
39 | FS, WT1
|
| Characteristics of testicular dysgenesis syndrome and decreased expression of SRY and SOX9 in Frasier syndrome.
|
| Schumacher V, Gueler B, Looijenga LH, Becker JU, Amann K, Engers R, Dotsch J, Stoop H, Schulz W, Royer-Pokora B.
|
| Mol Reprod Dev 75(9):1484-94.
2008
|
40 | WT1, WT1, WAGR
|
| A CTCF-binding silencer regulates the imprinted genes AWT1 and WT1-AS and exhibits sequential epigenetic defects during Wilms' tumourigenesis.
|
| Hancock AL, Brown KW, Moorwood K, Moon H, Holmgren C, Mardikar SH, Dallosso AR, Klenova E, Loukinov D, Ohlsson R, Lobanenkov VV, Malik K.
|
| Hum Mol Genet 16(3):343-54. Epub 2007 Jan 8. 2007
|
41 | IGF2, BWS, WT1
|
| Paternally inherited submicroscopic duplication at 11p15.5 implicates insulin-like growth factor II in overgrowth and Wilms' tumorigenesis.
|
| Algar EM, St Heaps L, Darmanian A, Dagar V, Prawitt D, Peters GB, Collins F.
|
| Cancer Res 67(5):2360-5. Epub 2007 Feb 26. 2007
|
42 | WAGR, WT1
|
| Complete sex reversal in a WAGR syndrome patient.
|
| Le Caignec C, Delnatte C, Vermeesch JR, Boceno M, Joubert M, Lavenant F, David A, Rival JM.
|
| Am J Med Genet A 143(22):2692-5. 2007
|
43 | WAGR, WT1, AN
|
| Raised risk of Wilms tumour in patients with aniridia and submicroscopic WT1 deletion.
|
| van Heyningen V, Hoovers JM, de Kraker J, Crolla JA.
|
| J Med Genet 44(12):787-90. Epub 2007 Jul 14. 2007
|
44 | WT1
|
| Human lymphocytes express the transcriptional regulator, Wilms tumor 1: the role of WT1 in mediating nitric oxide-dependent repression of lymphocyte proliferation.
|
| Marcet-Palacios M, Davoine F, Adamko DJ, Moqbel R, Befus AD.
|
| Biochem Biophys Res Commun 363(2):283-7. Epub 2007 Sep 4. 2007
|
45 | WAGR, PAX6, WT1
|
| WAGR(O?) syndrome and congenital ptosis caused by an unbalanced t(11;15)(p13;p11.2)dn demonstrating a 7 megabase deletion by FISH.
|
| Lennon PA, Scott DA, Lonsdorf D, Wargowski DS, Kirkpatrick S, Patel A, Cheung SW.
|
| Am J Med Genet A 140(11):1214-8. 2006
|
46 | WT1, SOX9
|
| The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis.
|
| Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Lecureuil C, Guillou F, Huff V.
|
| Proc Natl Acad Sci U S A 103(32):11987-92. Epub 2006 Jul 28. 2006
|
47 | WT1, WTAP
|
| Wilms' tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA.
|
| Horiuchi K, Umetani M, Minami T, Okayama H, Takada S, Yamamoto M, Aburatani H, Reid PC, Housman DE, Hamakubo T, Kodama T.
|
| Proc Natl Acad Sci U S A 103(46):17278-83. Epub 2006 Nov 6. 2006
|
48 | ACTN4, CD2AP, NPHS1, NPHS2, SRN1, SRN4, WT1
|
| Mutations in the Wilms' tumor 1 gene cause isolated steroid resistant nephrotic syndrome and occur in exons 8 and 9.
|
| Mucha B, Ozaltin F, Hinkes BG, Hasselbacher K, Ruf RG, Schultheiss M, Hangan D, Hoskins BE, Everding AS, Bogdanovic R, Seeman T, Hoppe B, Hildebrandt F; Members of the APN Study Group.
|
| Pediatr Res 59(2):325-31. 2006
|
49 | CTCF, H19, IGF2, BWS, WT1
|
| Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.
|
| Prawitt D, Enklaar T, Gartner-Rupprecht B, Spangenberg C, Oswald M, Lausch E, Schmidtke P, Reutzel D, Fees S, Lucito R, Korzon M, Brozek I, Limon J, Housman DE, Pelletier J, Zabel B.
|
| Proc Natl Acad Sci U S A 102(11):4085-90. Epub 2005 Mar 2. 2005
|
50 | WT1, EP300
|
| Histone acetyltransferase p300 promotes the activation of human WT1 promoter and intronic enhancer.
|
| Shao Y, Lu J, Zhang G, Liu C, Huang B.
|
| Arch Biochem Biophys 436(1):62-8. 2005
|
51 | WT1
|
| Genomic imprinting at the WT1 gene involves a novel coding transcript (AWT1) that shows deregulation in Wilms' tumours.
|
| Dallosso AR, Hancock AL, Brown KW, Williams AC, Jackson S, Malik K.
|
| Hum Mol Genet 13(4):405-15. Epub 2003 Dec 17. 2004
|
52 | WT1, SRD5A2, AR, PPSH
|
| Mutation analysis of five candidate genes in Chinese patients with hypospadias.
|
| Wang Y, Li Q, Xu J, Liu Q, Wang W, Lin Y, Ma F, Chen T, Li S, Shen Y.
|
| Eur J Hum Genet 12(9):706-12. 2004
|
53 | BASP1, WT1
|
| BASP1 is a transcriptional cosuppressor for the Wilms' tumor suppressor protein WT1.
|
| Carpenter B, Hill KJ, Charalambous M, Wagner KJ, Lahiri D, James DI, Andersen JS, Schumacher V, Royer-Pokora B, Mann M, Ward A, Roberts SG.
|
| Mol Cell Biol 24(2):537-49. 2004
|
54 | WT1, ETV4
|
| Activation of the WT1 tumor suppressor gene promoter by Pea3.
|
| Discenza MT, Vaz D, Hassell JA, Pelletier J.
|
| FEBS Lett 560(1-3):183-91. 2004
|
55 | WT1
|
| Overexpression of the Wilms' tumor gene WT1 in human bone and soft-tissue sarcomas.
|
| Ueda T, Oji Y, Naka N, Nakano Y, Takahashi E, Koga S, Asada M, Ikeba A, Nakatsuka S, Abeno S, Hosen N, Tomita Y, Aozasa K, Tamai N, Myoui A, Yoshikawa H, Sugiyama H.
|
| Cancer Sci 94(3):271-6. 2003
|
56 | DDS, WT1
|
| Murine Denys-Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.
|
| Patek CE, Fleming S, Miles CG, Bellamy CO, Ladomery M, Spraggon L, Mullins J, Hastie ND, Hooper ML.
|
| Hum Mol Genet 12(18):2379-94. Epub 2003 Jul 22. 2003
|
57 | WT1
|
| The complex life of WT1.
|
| Wagner KD, Wagner N, Schedl A.
|
| J Cell Sci 116(Pt 9):1653-8. Review.PMID: 12665546 2003
|
58 | WT1
|
| WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis.
|
| Guo JK, Menke AL, Gubler MC, Clarke AR, Harrison D, Hammes A, Hastie ND, Schedl A.
|
| Hum Mol Genet 11(6):651-9. 2002
|
59 | COL1A1, DDIT3, EWSR1, SUZ12, JAZF1, NR4A3, WT1
|
| Cytogenetics and molecular genetics of bone and soft-tissue tumors.
|
| Sandberg AA.
|
| Am J Med Genet 115(3):189-93. 2002
|
60 | GBGT1, WT1
|
| An unusual phenotype of Frasier syndrome due to IVS9 +4C>T mutation in the WT1 gene: predominantly male ambiguous genitalia and absence of gonadal dysgenesis.
|
| Melo KF, Martin RM, Costa EM, Carvalho FM, Jorge AA, Arnhold IJ, Mendonca BB.
|
| J Clin Endocrinol Metab 87(6):2500-5. Review. 2002
|
61 | WT1
|
| A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development.
|
| Natoli TA, Liu J, Eremina V, Hodgens K, Li C, Hamano Y, Mundel P, Kalluri R, Miner JH, Quaggin SE, Kreidberg JA.
|
| J Am Soc Nephrol 13(8):2058-67. 2002
|
62 | WT1
|
| Downregulation of Wilms' tumor 1 protein inhibits breast cancer proliferation.
|
| Zapata-Benavides P, Tuna M, Lopez-Berestein G, Tari AM.
|
| Biochem Biophys Res Commun 295(4):784-90. 2002
|
63 | GBGT1, WT1
|
| Molecular analysis of Frasier syndrome: mutation in the WT1 gene in a girl with gonadal dysgenesis and nephronophthisis.
|
| Perez de Nanclares G, Castano L, Bilbao JR, Vallo A, Rica I, Vela A, Martul P.
|
| J Pediatr Endocrinol Metab 15(7):1047-50. 2002
|
64 | WT1
|
| The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells.
|
| Ellisen LW, Carlesso N, Cheng T, Scadden DT, Haber DA.
|
| EMBO J 20(8):1897-909. 2001
|
65 | DDS, GBGT1, WT1
|
| Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation.
|
| Hammes A, Guo JK, Lutsch G, Leheste JR, Landrock D, Ziegler U, Gubler MC, Schedl A.
|
| Cell 106(3):319-29. 2001
|
66 | WT1
|
| Mutations/deletions of the WT1 gene, loss of heterozygosity on chromosome arms 11p and 11q, chromosome ploidy and histology in Wilms' tumors in Japan.
|
| Nakadate H, Yokomori K, Watanabe N, Tsuchiya T, Namiki T, Kobayshi H, Suita S, Tsunematsu Y, Horikoshi Y, Hatae Y, Endo M, Komada Y, Eguchi H, Toyoda Y, Kikuta A, Kobayashi R, Kaneko Y.
|
| Int J Cancer 94(3):396-400. 2001
|
67 | IDMS, WT1
|
| Constitutional WT1 correlate with clinical features in children with progressive nephropathy.
|
| Takata A, Kikuchi H, Fukuzawa R, Ito S, Honda M, Hata J.
|
| J Med Genet 37(9):698-701. No abstract available. 2000
|
68 | GBGT1, WT1
|
| The same mutation affecting the splicing of WT1 gene is present on Frasier syndrome patients with or without Wilms' tumor.
|
| Barbosa AS, et al.
|
| Hum Mutat 13 : 146-153. 1999
|
69 | PAX2, WT1
|
| WT1 and PAX-2 podocyte expression in Denys-Drash syndrome and isolated diffuse mesangial sclerosis.
|
| Yang Y, et al.
|
| Am J Pathol 154(1):181-92. 1999
|
70 | NR0B2, WT1
|
| The Wilms' tumor suppressor gene (wt1) product regulates Dax-1 gene expression during gonadal differentiation.
|
| Kim J, et al.
|
| Mol Cell Biol 19(3):2289-99. 1999
|
71 | WT1
|
| The Wilms' tumor gene WT1 is a good marker for diagnosis of disease progression of myelodysplastic syndromes.
|
| Tamaki H, et al.
|
| Leukemia 13(3):393-9. 1999
|
72 | WT1, TSG11G
|
| Induction of rat WT1 gene expression correlates with human chromosome 11p11.2-p12-mediated suppression of tumorigenicity in rat liver epithelial tumor cell lines.
|
| Coleman WB, et al.
|
| Int J Oncol 14(5):957-63. 1999
|
73 | WT1
|
| WT1 and GATA1 expression in myelodysplastic syndrome and acute leukemia.
|
| Patmasiriwat P, et al.
|
| Leukemia 13(6):891-900. 1999
|
74 | WT1
|
| Initial differentiation of the metanephric mesenchyme is independent of WT1 and the ureteric bud.
|
| Donovan MJ, et al.
|
| Dev Genet 24(3-4):252-62 1999
|
75 | WT1
|
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76 | GBGT1, WT1
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77 | GBGT1, WT1
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78 | WT1
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79 | GBGT1, WT1
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80 | WT1
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81 | GBGT1, WT1
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82 | IDMS, WT1
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83 | IDMS, WT1
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84 | NR0B2, DDS, NR5A1, WT1
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85 | APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
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86 | GUD, WT1
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87 | WT1
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88 | PAX6, WT1
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89 | NPHS4, WT1
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| Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database.
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90 | WT1
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91 | WT1
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92 | GBGT1, WT1, FS
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| Donor splice-site mutations in WT1 are responsible for Frasier syndrome.
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93 | DDS, GBGT1, WT1
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94 | WT1
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95 | WT1
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96 | TSG11A, WT1
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97 | SLC26A4, WT1
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98 | WT1
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99 | WT1
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100 | DSRCT, EWSR1, WT1
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101 | SLC26A4, WT1
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| DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome WT1 point mutations.
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102 | WT1
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103 | WT1
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104 | GBGT1, WT1
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105 | WT1
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| Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing.
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| Cell 81(3):391-401 1995
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106 | WT1, SLC26A4
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107 | WT1
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108 | WT1
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| Infrequent mutation of the WT1 gene in 77 Wilms' tumors.
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109 | WT1, TSG11A
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110 | SLC26A4, WT1
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| WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion.
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| Genomics 21 : 663-665. 1994
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111 | EWSR1, WT1
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112 | WT1, WT2
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| Br J Cancer 69 : 1072-1077. 1994
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113 | AN, WT1, WAGR
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| Hum Genet 94 : 331-338. 1994
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114 | WT1, WAGR
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| The Wilms tumour (WT1) gene is mutated in a secondary leukaemia in a WAGR patient.
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| Hum Mol Genet 3 : 1633-1637. 1994
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115 | WT1
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| Novel replication inhibitory function of the developmental regulator/transcription repressor protein WT1 encoded by the Wilms'tumor gene.
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116 | WT1, WT2
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117 | WT1
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| Kidney Int 46 : 1264-1279. 1994
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118 | WT1
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119 | WT1
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120 | WT1, SLC26A4
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| Hum Mol Genet 2 : 259-264. 1993
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121 | WT1, SLC26A4
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| A point mutation found in the WT1 gene in a sporadic Wilms' tumor without genitourinary abnormalities is identical with the most frequent point mutation in Denys-Drash syndrome.
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122 | WT1, SLC26A4
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123 | WT1, SLC26A4
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124 | WT1
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| PCR detection of 9 polymorphisms in the WT1 gene.
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125 | TSG11A, WT1
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126 | WT1, WAGR
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127 | SLC26A4, FS, WT1
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128 | WT1
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| Proc Natl Acad Sci U S A 90 : 1416-1419. 1993
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129 | WT1, SLC26A4
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| Exon skipping due to a mutation in a donor splice site in the WT-1 gene is associated with Wilms' tumor and severe genital malformations.
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| Hum Genet 91 : 599-604. 1993
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130 | TSG11A, WT1
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| The Wilms tumour gene WT1 is expressed in murine mesoderm-derived tissues and mutated in a human mesothelioma.
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131 | WT1
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| Insertional inactivation of the WT1 gene in tumour cells from a patient with WAGR syndrome.
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| Hum Genet 92 : 83-86. 1993
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132 | WT1, WT2, TSG11A, ST5
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| Deletion of WT1 and WIT1 genes and loss of heterozygosity on chromosome 11p in Wilms tumors in Japan.
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| Jpn J Cancer Res 84 : 616-624. 1993
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133 | WT1, SLC26A4
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| J Med Genet 30 : 767-772. 1993
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134 | WT1
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| Low frequency of mutations in the WT1 coding region in Wilms' tumor.
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| Genes Chromosomes Cancer 8 : 74-79. 1993
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135 | SLC26A4, WT1
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| A novel insertional mutation at the third zinc finger coding region of the WT1 gene in Denys-Drash syndrome.
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136 | WT1
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137 | WT1
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| WT-1 is required for early kidney development.
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| Cell 74(4):679-91 1993
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138 | WT1
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| Sequence of the WT1 upstream region including the Wit-1 gene.
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139 | WT1
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| The genomic organization and expression of the WT1 gene.
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140 | WT1
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| Intragenic homozygous deletion of the WT1 gene in Wilms' tumor.
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141 | WT1
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142 | WT1, SLC26A4
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143 | WT1
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144 | WT1, SLC26A4
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145 | WT1, WAGR
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146 | WT1
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147 | WT1
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148 | WT1
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149 | WT1
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150 | WT1, WT2, TSG11A, ST5
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| Loss of heterozygosity mapping in Wilms tumor indicates the involvement of three distinct regions and a limited role for nondisjunction or mitotic recombination.
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151 | WT1
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152 | WT1
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153 | WT1
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| A tumor chromosome rearrangement further defines the 11p13 Wilms tumor locus.
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154 | WT1
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| Direct pulsed field gel electrophoresis of Wilms' tumors shows that DNA deletions in 11p13 are rare.
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155 | WT1
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| Familial predisposition to Wilms tumor does not segregate with the WT1 gene.
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156 | WT1
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157 | WAGR, WT1
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158 | WT1
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159 | WT1
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160 | WT1
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161 | WT1
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162 | WT1
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163 | WT1
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164 | WAGR, WT1
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165 | TSG16B, WT1
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166 | WT1, WT2
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167 | WT1
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168 | WT1
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169 | WT1
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170 | WT1
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171 | WT1
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172 | WT1, D11S378
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173 | WT1
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174 | WT1
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175 | WT1
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176 | WT1, LMO2, TRD@
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177 | WT1, WT2
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178 | D11S87, TRA@, WT1
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