| 1 | ALS10, TARDBP
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| Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis
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| Prasad A, Bharathi V, Sivalingam V, Girdhar A, Patel BK.
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| Front Mol Neurosci. Feb 14;12:25. doi: 10.3389/fnmol.2019.00025. 2019
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| 2 | ALS10, TARDBP, TTBK1, TTBK2
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| The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43.
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| Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC.
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| PLoS Genet LoS Genet. 2014 2014
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| 3 | ALS10, TARDBP
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| The ALS disease protein TDP-43 is actively transported in motor neuron axons and regulates axon outgrowth.
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| Fallini C, Bassell GJ, Rossoll W.
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| Hum Mol Genet 21(16):3703-18. doi: 10.1093/hmg/dds205. Epub 2012 May 28.
2012
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| 4 | ALS10, TARDBP
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| Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo.
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| Kabashi E, Lin L, Tradewell ML, Dion PA, Bercier V, Bourgouin P, Rochefort D, Bel Hadj S, Durham HD, Vande Velde C, Rouleau GA, Drapeau P.
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| Hum Mol Genet 19(4):671-83. Epub 2009 Dec 3.PMID: 19959528 2010
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| 5 | ALS10, ALS6, FUS, TARDBP
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| ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.
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| Ling SC, Albuquerque CP, Han JS, Lagier-Tourenne C, Tokunaga S, Zhou H, Cleveland DW.
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| Proc Natl Acad Sci U S A 107(30):13318-23. Epub 2010 Jul 12.PMID: 20624952 2010
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| 6 | ALS1, ALS10, ALS6, ALS8, ALS9, ANG, FUS, SOD1, TARDBP, VAPB
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| SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations.
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| Millecamps S, Salachas F, Cazeneuve C, Gordon P, Bricka B, Camuzat A, Guillot-Noël L, Russaouen O, Bruneteau G, Pradat PF, Le Forestier N, Vandenberghe N, Danel-Brunaud V, Guy N, Thauvin-Robinet C, Lacomblez L, Couratier P, Hannequin D, Seilhean D, Le Ber I, Corcia P, Camu W, Brice A, Rouleau G, LeGuern E, Meininger V.
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| J Med Genet 47(8):554-60. Epub 2010 Jun 24.PMID: 20577002 2010
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| 7 | ALS10, ATXN2, TARDBP
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| Neurodegeneration: An expansion in ALS genetics.
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| Lagier-Tourenne C, Cleveland DW.
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| Nature 466(7310):1052-3. No abstract available. 2010
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| 8 | ALS10, TARDBP
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| Contribution of TARDBP mutations to sporadic amyotrophic lateral sclerosis.
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| Daoud H, Valdmanis PN, Kabashi E, Dion P, Dupré N, Camu W, Meininger V, Rouleau GA.
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| J Med Genet 46(2):112-4. Epub 2008 Oct 17.
2009
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| 9 | ALS10, FTLD, TARDBP
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| Mutations in TDP-43 link glycine-rich domain functions to amyotrophic lateral sclerosis.
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| Pesiridis GS, Lee VM, Trojanowski JQ.
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| Hum Mol Genet 18(R2):R156-62. Review.PMID: 19808791 2009
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| 10 | TARDBP, ALS10
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| TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis.
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| Sreedharan J, Blair IP, Tripathi VB, Hu X, Vance C, Rogelj B, Ackerley S, Durnall JC, Williams KL, Buratti E, Baralle F, de Belleroche J, Mitchell JD, Leigh PN, Al-Chalabi A, Miller CC, Nicholson G, Shaw CE.
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| Science 319(5870):1668-72. Epub 2008 Feb 28. 2008
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| 11 | TARDBP, ALS10
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| TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis.
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| Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, Vande Velde C, Bouchard JP, Lacomblez L, Pochigaeva K, Salachas F, Pradat PF, Camu W, Meininger V, Dupre N, Rouleau GA.
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| Nat Genet 40(5):572-4. Epub 2008 Mar 30. 2008
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| 12 | ALS10, TARDBP, TDP-43, TDP43
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| TDP-43: an emerging new player in neurodegenerative diseases
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| I-Fan Wang*, Lien-Szu Wu* and C-K. James Shen
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| Trends in Molecular Medicine 14(11):479-85 2008
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| 13 | ALS10, TARDBP
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| TDP-43 A315T mutation in familial motor neuron disease.
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| Gitcho MA, Baloh RH, Chakraverty S, Mayo K, Norton JB, Levitch D, Hatanpaa KJ, White CL 3rd, Bigio EH, Caselli R, Baker M, Al-Lozi MT, Morris JC, Pestronk A, Rademakers R, Goate AM, Cairns NJ.
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| Ann Neurol 63(4):535-8.PMID: 18288693 2008
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| 14 | ALS10, FTLD, TARDBP
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| TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations.
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| Seelaar H, Schelhaas HJ, Azmani A, Küsters B, Rosso S, Majoor-Krakauer D, de Rijik MC, Rizzu P, ten Brummelhuis M, van Doorn PA, Kamphorst W, Willemsen R, van Swieten JC.
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| Brain 130(Pt 5):1375-85. Epub 2007 Mar 14.
2007
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| 15 | ALS10, ALSPD, FTLD, TARDBP
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| TDP-43 is deposited in the Guam parkinsonism-dementia complex brains.
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| Hasegawa M, Arai T, Akiyama H, Nonaka T, Mori H, Hashimoto T, Yamazaki M, Oyanagi K.
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| Brain 130(Pt 5):1386-94. Epub 2007 Apr 17. 2007
|