| 1 | SLC2A1, SLC2A8
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| GLUT1 and GLUT8 support lactose synthesis in Golgi of murine mammary epithelial cells.
|
| Villagrán M, Muñoz M, Inostroza E, Venegas C, Ruminot I, Parra-Valencia E, Maldonado M, Del Pozo R, Rivas CI, Vera JC, Mardones L.
|
| J Physiol Biochem 75(2):209-215. doi: 10.1007/s13105-019-00679-3. Epub 2019 Apr 24.
2019
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| 2 | G6PD, SLC2A1
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| Heat shock induces the cellular antioxidant defenses peroxiredoxin, glutathione and glucose 6-phosphate dehydrogenase through Nrf2.
|
| Tchouagué M, Grondin M, Glory A, Averill-Bates D.
|
| Chem Biol Interact 310:108717. doi: 10.1016/j.cbi.2019.06.030. Epub 2019 Jun 21.
2019
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| 3 | CYGB, HK2, SLC2A1
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| The epigenetically downregulated factor CYGB suppresses breast cancer through inhibition of glucose metabolism
|
| Feng Y, Wu M, Li S, He X, Tang J, Peng W, Zeng B, Deng C, Ren G, Xiang T.
|
| J Exp Clin Cancer Res. Dec 13;37(1):313. doi: 10.1186/s13046-018-0979-9. 2018
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| 4 | PPARD, SLC1A5, SLC2A1
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| PPARδ promotes tumor progression via activation of Glut1 and SLC1-A5 transcription.
|
| Zhang W, Xu Y, Xu Q, Shi H, Shi J, Hou Y.
|
| Carcinogenesis 38(7):748-755. doi: 10.1093/carcin/bgx035.
2017
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| 5 | SLC2A1, TBC1D5
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| Autophagy-Dependent Shuttling of TBC1D5 Controls Plasma Membrane Translocation of GLUT1 and Glucose Uptake.
|
| Roy S, Leidal AM, Ye J, Ronen SM, Debnath J.
|
| Mol Cell. Jul 6;67(1):84-95.e5. doi: 10.1016/j.molcel.2017.05.020. Epub 2017 Jun 8. 2017
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| 6 | HK2, SLC2A1, TRAF3
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| TRAF3 deficiency promotes metabolic reprogramming in B cells
|
| Mambetsariev N, Lin WW, Wallis AM, Stunz LL, Bishop GA
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| Sci Rep. Oct 18;6:35349. doi: 10.1038/srep35349. 2016
|
| 7 | DYT10, DYT69, DYT8, PNKD, PRRT2, SLC2A1
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| The clinical and genetic heterogeneity of paroxysmal dyskinesias.
|
| Gardiner AR, Jaffer F, Dale RC, Labrum R, Erro R, Meyer E, Xiromerisiou G, Stamelou M, Walker M, Kullmann D, Warner T, Jarman P, Hanna M, Kurian MA, Bhatia KP, Houlden H.
|
| Brain 138(Pt 12):3567-80. doi: 10.1093/brain/awv310. Review.
2015
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| 8 | SLC2A1
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| Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization.
|
| Foran E, Rosenblum L, Bogush A, Pasinelli P, Trotti D.
|
| Glia 62(8):1241-53. doi: 10.1002/glia.22677. Epub 2014 Apr 21.
2014
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| 9 | SLC2A1, SLC2A10, SLC2A12, SLC2A9
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| Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and -12, in vascular smooth muscle cells.
|
| Pyla R, Poulose N, Jun JY, Segar L.
|
| Am J Physiol Cell Physiol 304(6):C574-89. doi: 10.1152/ajpcell.00275.2012. Epub 2013 Jan 9.
2013
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| 10 | DYT18, DYT9, SLC2A1
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| Paroxysmal choreoathetosis/spasticity (DYT9) is caused by a GLUT1 defect.
|
| Weber YG, Kamm C, Suls A, Kempfle J, Kotschet K, Schüle R, Wuttke TV, Maljevic S, Liebrich J, Gasser T, Ludolph AC, Van Paesschen W, Schöls L, De Jonghe P, Auburger G, Lerche H.
|
| Neurology 77(10):959-64. Epub 2011 Aug 10.
2011
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| 11 | FGF21, KLB, SLC2A1
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| Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes.
|
| Ge X, Chen C, Hui X, Wang Y, Lam KS, Xu A.
|
| J Biol Chem 286(40):34533-41. Epub 2011 Aug 16.
2011
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| 12 | SLC2A1
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| Stomatin-deficient cryohydrocytosis results from mutations in SLC2A1: a novel form of GLUT1 deficiency syndrome.
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| Flatt JF, Guizouarn H, Burton NM, Borgese F, Tomlinson RJ, Forsyth RJ, Baldwin SA, Levinson BE, Quittet P, Aguilar-Martinez P, Delaunay J, Stewart GW, Bruce LJ.
|
| Blood 118(19):5267-77. doi: 10.1182/blood-2010-12-326645. Epub 2011 Jul 26.
2011
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| 13 | SLC2A1
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| Uncovering microdeletions in patients with severe Glut-1 deficiency syndrome using SNP oligonucleotide microarray analysis.
|
| Levy B, Wang D, Ullner PM, Engelstad K, Yang H, Nahum O, Chung WK, De Vivo DC.
|
| Mol Genet Metab 100(2):129-35. Epub 2010 Mar 17.
2010
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| 14 | SCD, SLC2A1
|
| Adipose-specific deletion of stearoyl-CoA desaturase 1 up-regulates the glucose transporter GLUT1 in adipose tissue.
|
| Hyun CK, Kim ED, Flowers MT, Liu X, Kim E, Strable M, Ntambi JM.
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| Biochem Biophys Res Commun 399(4):480-6. Epub 2010 Jul 22. 2010
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| 15 | GPC3, SLC2A1
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| Glypican 3 binds to GLUT1 and decreases glucose transport activity in hepatocellular carcinoma cells.
|
| Cho HS, Ahn JM, Han HJ, Cho JY.
|
| J Cell Biochem 111(5):1252-9. doi: 10.1002/jcb.22848.
2010
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| 16 | GIPC1, SLC2A1
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| An essential role for the Glut1 PDZ-binding motif in growth factor regulation of Glut1 degradation and trafficking.
|
| Wieman HL, Horn SR, Jacobs SR, Altman BJ, Kornbluth S, Rathmell JC.
|
| Biochem J 418(2):345-67. 2009
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| 17 | SLC2A1
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| GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis.
|
| Amann T, Maegdefrau U, Hartmann A, Agaimy A, Marienhagen J, Weiss TS, Stoeltzing O, Warnecke C, Schölmerich J, Oefner PJ, Kreutz M, Bosserhoff AK, Hellerbrand C.
|
| Am J Pathol 174(4):1544-52. Epub 2009 Mar 12.
2009
|
| 18 | SLC2A1
|
| Facilitative glucose transporter type 1 is differentially regulated by progesterone and estrogen in murine and human endometrial stromal cells.
|
| Frolova A, Flessner L, Chi M, Kim ST, Foyouzi-Yousefi N, Moley KH.
|
| Endocrinology 150(3):1512-20. Epub 2008 Oct 23.
2009
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| 19 | SLC2A1
|
| Glucose transporter-1 expression and prognostic significance in pancreatic carcinogenesis.
|
| Pizzi S, Porzionato A, Pasquali C, Guidolin D, Sperti C, Fogar P, Macchi V, De Caro R, Pedrazzoli S, Parenti A.
|
| Histol Histopathol 24(2):175-85.
2009
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| 20 | SLC2A1
|
| Expression of Glut-1 is a prognostic marker for oral squamous cell carcinoma patients.
|
| Eckert AW, Lautner MH, Taubert H, Schubert J, Bilkenroth U.
|
| Oncol Rep 20(6):1381-5.
2008
|
| 21 | SLC2A1
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| Apigenin inhibits the GLUT-1 glucose transporter and the phosphoinositide 3-kinase/Akt pathway in human pancreatic cancer cells.
|
| Melstrom LG, Salabat MR, Ding XZ, Milam BM, Strouch M, Pelling JC, Bentrem DJ.
|
| Pancreas 37(4):426-31.
2008
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| 22 | SLC2A1
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| Expression of glucose transporter 1 is associated with loss of heterozygosity of chromosome 1p in oligodendroglial tumors WHO grade II.
|
| Stockhammer F, von Deimling A, Synowitz M, Blechschmidt C, van Landeghem FK.
|
| J Mol Histol 39(5):553-60. Epub 2008 Aug 26.
2008
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| 23 | SLC2A1
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| Paroxysmal exercise-induced dyskinesia and epilepsy is due to mutations in SLC2A1, encoding the glucose transporter GLUT1.
|
| Suls A, Dedeken P, Goffin K, Van Esch H, Dupont P, Cassiman D, Kempfle J, Wuttke TV, Weber Y, Lerche H, Afawi Z, Vandenberghe W, Korczyn AD, Berkovic SF, Ekstein D, Kivity S, Ryvlin P, Claes LR, Deprez L, Maljevic S, Vargas A, Van Dyck T, Goossens D, Del-Favero J, Van Laere K, De Jonghe P, Van Paesschen W.
|
| Brain 131(Pt 7):1831-44. Epub 2008 Jun 24.
2008
|
| 24 | DYT18, SLC2A1
|
| GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesias and induce hemolytic anemia by a cation leak.
|
| Weber YG, Storch A, Wuttke TV, Brockmann K, Kempfle J, Maljevic S, Margari L, Kamm C, Schneider SA, Huber SM, Pekrun A, Roebling R, Seebohm G, Koka S, Lang C, Kraft E, Blazevic D, Salvo-Vargas A, Fauler M, Mottaghy FM, Münchau A, Edwards MJ, Presicci A, Margari F, Gasser T, Lang F, Bhatia KP, Lehmann-Horn F, Lerche H.
|
| J Clin Invest 118(6):2157-68.
2008
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| 25 | SLC2A1, SLC2A4, SGK1
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| Role of SGK1 kinase in regulating glucose transport via glucose transporter GLUT4.
|
| Jeyaraj S, Boehmer C, Lang F, Palmada M.
|
| Biochem Biophys Res Commun 356(3):629-35. Epub 2007 Mar 12. 2007
|
| 26 | DEL1P34,SLC2A1
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| A novel microdeletion in 1(p34.2p34.3), involving the SLC2A1 (GLUT1) gene, and severe delayed development.
|
| Vermeer S, Koolen DA, Visser G, Brackel HJ, van der Burgt I, de Leeuw N, Willemsen MA, Sistermans EA, Pfundt R, de Vries BB.
|
| Dev Med Child Neurol 49(5):380-4. 2007
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| 27 | SLC2A1
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| Disease-associated Glut1 single amino acid substitute mutations S66F, R126C, and T295M constitute Glut1-deficiency states in vitro.
|
| Wong HY, Law PY, Ho YY.
|
| Mol Genet Metab 90(2):193-8. Epub 2006 Oct 18. 2007
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| 28 | PACSIN3, SLC2A1
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| PACSIN3 overexpression increases adipocyte glucose transport through GLUT1.
|
| Roach W, Plomann M.
|
| Biochem Biophys Res Commun 355(3):745-50. Epub 2007 Feb 12.
2007
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| 29 | SLC2A1
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| Atypical GLUT1 deficiency with prominent movement disorder responsive to ketogenic diet.
|
| Friedman JR, Thiele EA, Wang D, Levine KB, Cloherty EK, Pfeifer HH, De Vivo DC, Carruthers A, Natowicz MR.
|
| Mov Disord 21(2):241-5. 2006
|
| 30 | SLC2A1
|
| Ultrastructure of human erythrocyte GLUT1.
|
| Graybill C, van Hoek AN, Desai D, Carruthers AM, Carruthers A.
|
| Biochemistry 45(26):8096-107. 2006
|
| 31 | SLC2A1
|
| Association between the GLUT1 gene polymorphism and the risk of diabetic nephropathy: a meta-analysis.
|
| Zintzaras E, Stefanidis I.
|
| J Hum Genet 50(2):84-91. Epub 2005 Jan 29. 2005
|
| 32 | SLC2A1
|
| The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV.
|
| Manel N, Kim FJ, Kinet S, Taylor N, Sitbon M, Battini JL.
|
| Cell 115(4):449-59.
2003
|
| 33 | SLC2A1
|
| Clinical significance of glucose transporter 1 (GLUT1) expression in human breast carcinoma.
|
| Kang SS, Chun YK, Hur MH, Lee HK, Kim YJ, Hong SR, Lee JH, Lee SG, Park YK.
|
| Jpn J Cancer Res 93(10):1123-8. 2002
|
| 34 | SLC2A1
|
| Autosomal dominant transmission of GLUT1 deficiency.
|
| Klepper J, Willemsen M, Verrips A, Guertsen E, Herrmann R, Kutzick C, Florcken A, Voit T.
|
| Hum Mol Genet 10(1):63-8. 2001
|
| 35 | SLC2A1, WRN
|
| Association of impaired phosphatidylinositol 3-kinase activity in GLUT1-containing vesicles with malinsertion of glucose transporters into the plasma membrane of fibroblasts from a patient with severe insulin resistance and clinical features of Werner syndrome.
|
| Kausch C, Hamann A, Uphues I, Niendorf A, Muller-Wieland D, Joost HG, Algenstaedt P, Dreyer M, Rudiger HW, Haring HU, Eckel J, Matthaei S.
|
| J Clin Endocrinol Metab 85(2):905-18. 2000
|
| 36 | SLC2A1
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| Mutational analysis of GLUT1 (SLC2A1) in Glut-1 deficiency syndrome.
|
| Wang D, Kranz-Eble P, De Vivo DC.
|
| Hum Mutat 16(3):224-31. 2000
|
| 37 | DYT18, SLC2A1
|
| A new family with paroxysmal exercise induced dystonia and migraine: a clinical and genetic study.
|
| Münchau A, Valente EM, Shahidi GA, Eunson LH, Hanna MG, Quinn NP, Schapira AH, Wood NW, Bhatia KP.
|
| J Neurol Neurosurg Psychiatry 68(5):609-14.
2000
|
| 38 | SLC2A1
|
| GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier.
|
| Seidner G, Alvarez MG, Yeh JI, O'Driscoll KR, Klepper J, Stump TS, Wang D, Spinner NB, Birnbaum MJ, De Vivo DC.
|
| Nat Genet 18(2):188-91. 1998
|
| 39 | SLC2A1
|
| High frequency of polymorphism but no mutations found in the GLUT1 glucose transporter gene in NIDDM and familial obesity by SSCP analysis.
|
| Baroni MG, et al.
|
| Hum Genet 102 : 479-482. 1998
|
| 40 | SLC2A1
|
| The ketogenic diet revisited: back to the future.
|
| Nordli DR, De Vivo DC.
|
| Epilepsia 38(7):743-9. Review. No abstract available. 1997
|
| 41 | SLC2A1, SLC2A2, SLC2A3, SLC2A4, SLC2A5, SLC2A6
|
| Structure, function and biosynthesis of GLUT1.
|
| Mueckler M, Hresko RC, Sato M.
|
| Biochem Soc Trans 25(3):951-4. Review. No abstract available. 1997
|
| 42 | SLC2A1, SLC2A4
|
| Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations.
|
| Pontirolli AE, et al.
|
| Acta Diabetol 33 : 193-197. 1996
|
| 43 | SLC2A1
|
| Affected sib-pair analysis of the SLC2A1 glucose transporter gene locus in non-insulin-dependent diabetes mellitus (NIDDM) : evidence for no linkage.
|
| Baroni MG, et al.
|
| Hum Genet 93 : 675-680. 1994
|
| 44 | SLC2A1
|
| Polymorphisms at the SLC2A1 (HepG2) and SLC2A4 (muscle/adipocyte) glucose transporter genes and non-insulin-dependent diabetes mellitus (NIDDM).
|
| Baroni MG, et al.
|
| Hum Genet 88 : 557-561. 1992
|
| 45 | SLC2A1, SLC2A2, SLC2A3, SLC2A3P1, SLC2A4, SLC2A5
|
| Facilitative glucose transporters : an expanding family.
|
| Gould GW, et al.
|
| Trends Biochem Sci 15 : 18-23. 1990
|
| 46 | SLC2A1, SLC2A2, SLC2A3, SLC2A3P1, SLC2A4, SLC2A5
|
| Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6).
|
| Kayano T, et al.
|
| J Biol Chem 265 : 13276-13282. 1990
|
| 47 | SLC2A1
|
| Stu I RFLP at the human Hep G2/erythrocyte glucose transporter (GLUT) gene locus.
|
| Li S, et al.
|
| Nucleic Acids Res 17 : 3330. 1989
|
| 48 | SLC2A1
|
| Identification of a novel gene encoding an insulin-responsive glucose transporter protein.
|
| Birnbaum MJ.
|
| Cell 57 : 305-315. 1989
|
| 49 | ALPL, FUCA1, D1S15, D1S16, D1S17, D1S18, D1S19, D1S20, D1S21, D1S22, D1S57, D1S9, D1S10, D1S11, D1S12, D1S13, D1S14, SLC2A1
|
| A genetic linkage map of 27 loci from PND to FY on the short arm of human chromosome 1.
|
| Dracopoli NC, Stanger BZ, Ito CY, Call KM, Lincoln SE, Lander ES, Housman DE.
|
| Am J Hum Genet 43 : 462-470. 1988
|
| 50 | SLC2A1, SLC2A3
|
| Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.
|
| Kayano T, et al.
|
| J Biol Chem 263 : 15245-15248. 1988
|
| 51 | SLC2A1
|
| Polymorphic human glucose transporter gene (GLUT) is on chromosome 1p31.3-p35.
|
| Shows TB, et al.
|
| Diabetes 36 : 546-549. 1987
|
| 52 | ALPL, RAB3IL1, RH, SLC2A1
|
| Multipoint linkage relationships of 6 loci on 1p (ALPL,GLUT,PGD,PGM1, PND,RH).
|
| Ardinger RH, et al.
|
| Am J Hum Genet 41 : A154. 1987
|
| 53 | SLC2A1
|
| Bgl II RFLP at the human erythrocyte/HepG2-type glucose transporter (GLUT) locus on chromosome 1.
|
| Xiang K, et al.
|
| Nucleic Acids Res 15 : 9101. 1987
|