| 1 | AD6, PSEN1
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| A presenilin-1 mutation identified in familial Alzheimer disease with cotton wool plaques causes a nearly complete loss of gamma-secretase activity.
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| Heilig EA, Xia W, Shen J, Kelleher RJ 3rd.
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| J Biol Chem 285(29):22350-9. Epub 2010 May 11.PMID: 20460383 2010
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| 2 | AD1, AD10, AD15, AD16, AD17, AD18, AD19, AD2, AD22, AD23, AD24, AD25, AD3, AD4, AD5, AD6, AD7, AD8, AD9
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| Genome-wide association studies in Alzheimer's disease.
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| Bertram L, Tanzi RE.
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| Hum Mol Genet 18(R2):R137-45. 2009
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| 3 | AD1, AD2, AD3, AD4, AD5, AD6, AD9, PARK1, PARK11, PARK3, PARK4, PARK5, PARK6, PARK7, PARK8, PARK9, PRKN
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| Chasing genes in Alzheimer's and Parkinson's disease.
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| Bertoli-Avella AM, Oostra BA, Heutink P.
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| Hum Genet 114(5):413-38. Epub 2004 Mar 04. 2004
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| 4 | AD6
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| Evidence for genetic linkage of Alzheimer's disease to chromosome 10q.
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| Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi RE.
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| Science 290(5500):2302-3. 2000
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| 5 | AD6
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| Susceptibility locus for Alzheimer's disease on chromosome 10.
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| Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM.
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| Science 290(5500):2304-5. 2000
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| 6 | AD6
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| Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees.
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| Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG.
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| Science 290(5500):2303-4. 2000
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