Citations for
1LIG1, UHRF1
Methylation of DNA Ligase 1 by G9a/GLP Recruits UHRF1 to Replicating DNA and Regulates DNA Methylation.
Ferry L, Fournier A, Tsusaka T, Adelmant G, Shimazu T, Matano S, Kirsh O, Amouroux R, Dohmae N, Suzuki T, Filion GJ, Deng W, de Dieuleveult M, Fritsch L, Kudithipudi S, Jeltsch A, Leonhardt H, Hajkova P, Marto JA, Arita K, Shinkai Y, Defossez PA.
Mol Cell 67(4):550-565.e5. doi: 10.1016/j.molcel.2017.07.012. Epub 2017 Aug 10. 2017
2LIG1, LIG3
Kinetic analyses of single-stranded break repair by human DNA ligase III isoforms reveal biochemical differences from DNA ligase I.
McNally JR, O'Brien PJ.
J Biol Chem 292(38):15870-15879. doi: 10.1074/jbc.M117.804625. Epub 2017 Jul 27. 2017
3LIG1
Relationship between genetic polymorphisms of DNA ligase 1 and non-small cell lung cancer susceptibility and radiosensitivity.
Tian H, He X, Yin L, Guo WJ, Xia YY, Jiang ZX.
Genet Mol Res 14(2):7047-52. doi: 10.4238/2015.June.26.14. 2015
4LIG1, LIG3, LIG4
DNA ligase I is not essential for mammalian cell viability.
Han L, Masani S, Hsieh CL, Yu K.
Cell Rep 7(2):316-20. doi: 10.1016/j.celrep.2014.03.024. Epub 2014 Apr 13. 2014
5LIG1, LIG3
DNA ligases I and III cooperate in alternative non-homologous end-joining in vertebrates.
Paul K, Wang M, Mladenov E, Bencsik-Theilen A, Bednar T, Wu W, Arakawa H, Iliakis G.
PLoS One 8(3):e59505. doi: 10.1371/journal.pone.0059505. Epub 2013 Mar 28. 2013
6LIG1, LIG3
Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells.
Arakawa H, Bednar T, Wang M, Paul K, Mladenov E, Bencsik-Theilen AA, Iliakis G.
Nucleic Acids Res 40(6):2599-610. doi: 10.1093/nar/gkr1024. Epub 2011 Nov 29. 2012
7LIG1, RFC1
Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair.
Peng Z, Liao Z, Dziegielewska B, Matsumoto Y, Thomas S, Wan Y, Yang A, Tomkinson AE.
J Biol Chem 287(44):36711-9. doi: 10.1074/jbc.M112.383570. Epub 2012 Sep 4. 2012
8LIG1, RFC1
Phosphorylation of serine 51 regulates the interaction of human DNA ligase I with replication factor C and its participation in DNA replication and repair.
Peng Z, Liao Z, Dziegielewska B, Matsumoto Y, Thomas S, Wan Y, Yang A, Tomkinson AE.
J Biol Chem 287(44):36711-9. doi: 10.1074/jbc.M112.383570. Epub 2012 Sep 4. 2012
9LIG1, LIG3
DNA ligase III promotes alternative nonhomologous end-joining during chromosomal translocation formation.
Simsek D, Brunet E, Wong SY, Katyal S, Gao Y, McKinnon PJ, Lou J, Zhang L, Li J, Rebar EJ, Gregory PD, Holmes MC, Jasin M.
PLoS Genet 7(6):e1002080. doi: 10.1371/journal.pgen.1002080. Epub 2011 Jun 2. 2011
10LIG1, LIG3
Disconnecting XRCC1 and DNA ligase III.
Katyal S, McKinnon PJ.
Cell Cycle 10(14):2269-75. Epub 2011 Jul 15. 2011
11LIG1, LIG3
DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair.
Gao Y, Katyal S, Lee Y, Zhao J, Rehg JE, Russell HR, McKinnon PJ.
Nature 471(7337):240-4. doi: 10.1038/nature09773. 2011
12LIG1
Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency.
Taylor MR, Conrad JA, Wahl D, O'Brien PJ.
J Biol Chem 286(26):23054-62. doi: 10.1074/jbc.M111.248831. Epub 2011 May 10. 2011
13LIG1
Phosphorylation of human DNA ligase I regulates its interaction with replication factor C and its participation in DNA replication and DNA repair.
Vijayakumar S, Dziegielewska B, Levin DS, Song W, Yin J, Yang A, Matsumoto Y, Bermudez VP, Hurwitz J, Tomkinson AE.
Mol Cell Biol 29(8):2042-52. doi: 10.1128/MCB.01732-08. Epub 2009 Feb 17. 2009
14LIG1
DNA ligase I and Nbs1 proteins associate in a complex and colocalize at replication factories.
Vago R, Leva V, Biamonti G, Montecucco A.
Cell Cycle 8(16):2600-7. Epub 2009 Aug 24. 2009
15LIG1, LIG3
Human DNA ligases I and III, but not ligase IV, are required for microhomology-mediated end joining of DNA double-strand breaks.
Liang L, Deng L, Nguyen SC, Zhao X, Maulion CD, Shao C, Tischfield JA.
Nucleic Acids Res 36(10):3297-310. Epub 2008 Apr 24. 2008
16LIG1
Human DNA ligase I completely encircles and partially unwinds nicked DNA.
Pascal JM, O'Brien PJ, Tomkinson AE, Ellenberger T.
Nature 432(7016):473-8. 2004
17LIG1
Human DNA ligase I efficiently seals nicks in nucleosomes.
Chafin DR, Vitolo JM, Henricksen LA, Bambara RA, Hayes JJ.
EMBO J 19(20):5492-501. 2000
18PCNA, LIG1
Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen.
Jonsson ZO, et al.
EMBO J 17(8):2412-25. 1998
19LIG1
DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability.
Bentley DJ, et al.
Nat Genet 13 : 489-491. 1996
20LIG1
Assignment of the gene encoding DNA ligase I to human chromosome 19q13.2-13.3.
Barnes DE, et al.
Genomics 12 : 164-166. 1992
21LIG1
Mutations in the DNA ligase I gene of an individual with immunodeficiencies and cellular hypersensitivity to DNA-damaging agents.
Barnes DE, et al.
Cell 69 : 495-503. 1992
22LIG1
Growth retardation and immunodeficiency in a patient with mutations in the DNA ligase I gene.
Webster ADB, et al.
Lancet 339 : 1508-1509. 1992
23LIG1
A new sequence variant of the human DNA ligase type I gene (LIG I).
Montecucco A, et al.
Nucleic Acids Res 19 : 6347. 1991
24LIG1
Human DNA ligase I cDNA: cloning and functional expression in saccharomyces cerevisiae.
Barnes DE, et al.
Proc Natl Acad Sci U S A 87 : 6679-6683. 1990