| 1 | FGF8, FGFR1, KAL6, NIHH |
| Nonsense mutations in FGF8 gene causing different degrees of human gonadotropin-releasing deficiency. | |
| Trarbach EB, Abreu AP, Silveira LF, Garmes HM, Baptista MT, Teles MG, Costa EM, Mohammadi M, Pitteloud N, Mendonca BB, Latronico AC. | |
| J Clin Endocrinol Metab 95(7):3491-6. Epub 2010 May 12. 2010 | |
| 2 | FGF8, KAL6 |
| Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice. | |
| Falardeau J, Chung WC, Beenken A, Raivio T, Plummer L, Sidis Y, Jacobson-Dickman EE, Eliseenkova AV, Ma J, Dwyer A, Quinton R, Na S, Hall JE, Huot C, Alois N, Pearce SH, Cole LW, Hughes V, Mohammadi M, Tsai P, Pitteloud N. | |
| J Clin Invest 118(8):2822-31. 2008 | |