| 1 | DEL11QD, ETS1, HLHS2
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| Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.
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| Ye M, Coldren C, Liang X, Mattina T, Goldmuntz E, Benson DW, Ivy D, Perryman MB, Garrett-Sinha LA, Grossfeld P.
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| Hum Mol Genet 19(4):648-56. Epub 2009 Nov 26.
2010
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| 2 | DEL11QD, HLHS2, JAM3
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| Deletion of JAM-C, a candidate gene for heart defects in Jacobsen syndrome, results in a normal cardiac phenotype in mice.
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| Ye M, Hamzeh R, Geddis A, Varki N, Perryman MB, Grossfeld P.
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| Am J Med Genet A 149A(7):1438-43.
2009
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| 3 | GJA1, HAND1, HLHS1, HLHS2, HLHS3, NKX2-5, NOTCH1
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| Hypoplastic left heart syndrome: new genetic insights.
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| Grossfeld P, Ye M, Harvey R.
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| J Am Coll Cardiol 53(12):1072-4. No abstract available.
2009
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| 4 | FAVD1, FAVD2, HLHS1, HLHS2
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| Hypoplastic left heart syndrome is heritable.
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| Hinton RB Jr, Martin LJ, Tabangin ME, Mazwi ML, Cripe LH, Benson DW.
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| J Am Coll Cardiol 50(16):1590-5. Epub 2007 Oct 1. 2007
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| 5 | DEL11QD, HLHS2, JAM3
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| Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis.
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| Phillips HM, Renforth GL, Spalluto C, Hearn T, Curtis AR, Craven L, Havarani B, Clement-Jones M, English C, Stumper O, Salmon T, Hutchinson S, Jackson MS, Wilson DI.
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| Genomics 79(4):475-8. 2002
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| 6 | HLHS2
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| Possible genes for left heart formation on 11q23.3.
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| Guenthard J, et al.
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| Ann Genet 37 : 143-146. 1994
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