1 | CR2, CVID7
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| Genetic CD21 deficiency is associated with hypogammaglobulinemia.
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| Thiel J, Kimmig L, Salzer U, Grudzien M, Lebrecht D, Hagena T, Draeger R, Völxen N, Bergbreiter A, Jennings S, Gutenberger S, Aichem A, Illges H, Hannan JP, Kienzler AK, Rizzi M, Eibel H, Peter HH, Warnatz K, Grimbacher B, Rump JA, Schlesier M.
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| J Allergy Clin Immunol 129(3):801-810.e6. Epub 2011 Oct 27. 2012
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2 | CR2
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| A crystal structure of the complex between human complement receptor 2 and its ligand C3d.
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| van den Elsen JM, Isenman DE.
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| Science. 332(6029):608-11. 2011
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3 | CR2
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| Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus.
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| Wu H, Boackle SA, Hanvivadhanakul P, Ulgiati D, Grossman JM, Lee Y, Shen N, Abraham LJ, Mercer TR, Park E, Hebert LA, Rovin BH, Birmingham DJ, Chang DM, Chen CJ, McCurdy D, Badsha HM, Thong BY, Chng HH, Arnett FC, Wallace DJ, Yu CY, Hahn BH, Cantor RM, Tsao BP.
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| Proc Natl Acad Sci U S A 104(10):3961-6. Epub 2007 Feb 22. 2007
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4 | CR2
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| Factor I-mediated processing of complement fragments on HIV immune complexes targets HIV to CR2-expressing B cells and facilitates B cell-mediated transmission of opsonized HIV to T cells.
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| Banki Z, Wilflingseder D, Ammann CG, Pruenster M, Mullauer B, Hollander K, Meyer M, Sprinzl GM, van Lunzen J, Stellbrink HJ, Dierich MP, Stoiber H.
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| J Immunol 177(5):3469-76. 2006
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5 | IFNA1, CR2
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| Characterization of human complement receptor type 2 (CR2/CD21) as a receptor for IFN-alpha: a potential role in systemic lupus erythematosus.
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| Asokan R, Hua J, Young KA, Gould HJ, Hannan JP, Kraus DM, Szakonyi G, Grundy GJ, Chen XS, Crow MK, Holers VM.
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| J Immunol 177(1):383-94. 2006
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6 | CR2
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| Complement receptor 1 and 2 deficiency increases coxsackievirus B3-induced myocarditis, dilated cardiomyopathy, and heart failure by increasing macrophages, IL-1beta, and immune complex deposition in the heart.
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| Fairweather D, Frisancho-Kiss S, Njoku DB, Nyland JF, Kaya Z, Yusung SA, Davis SE, Frisancho JA, Barrett MA, Rose NR.
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| J Immunol. 176(6):3516-24. 2006
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7 | CFHR4, CR1, CR2, CR1L, CFHR1, CFHR2, CFHR3, CFHR5
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| FHR-4A: a new factor H-related protein is encoded by the human FHR-4 gene.
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| Jozsi M, Richter H, Loschmann I, Skerka C, Buck F, Beisiegel U, Erdei A, Zipfel PF.
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| Eur J Hum Genet 13(3):321-9. 2005
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8 | CR1, CR2
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| Complement receptor 1 polymorphisms associated with resistance to severe malaria in Kenya.
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| Thathy V, Moulds JM, Guyah B, Otieno W, Stoute JA.
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| Malar J 4:54. 2005
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9 | CR2
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| Gill MB, Roecklein-Canfield J, Sage DR, Zambela-Soediono M, Longtine N, Uknis M, Fingeroth JD.
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| Gill MB, Roecklein-Canfield J, Sage DR, Zambela-Soediono M, Longtine N, Uknis M, Fingeroth JD.
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| J Cell Sci. 117(Pt 13):2709-20 2004
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10 | CR2
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| Functional analysis of the human complement receptor 2 (CR2/CD21) promoter: characterization of basal transcriptional mechanisms.
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| Ulgiati D, Pham C, Holers VM.
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| J Immunol 168(12):6279-85. 2002
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11 | CR2
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| CR2/CD21 proximal promoter activity is critically dependent on a cell type-specific repressor.
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| Ulgiati D, Holers VM.
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| J Immunol 167(12):6912-9. 2001
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12 | CR2
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| Kinetic analysis of the interactions of complement receptor 2 (CR2, CD21) with its ligands C3d, iC3b, and the EBV glycoprotein gp350/220.
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| Sarrias MR, Franchini S, Canziani G, Argyropoulos E, Moore WT, Sahu A, Lambris JD.
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| J Immunol 167(3):1490-9. 2001
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13 | CR2
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| Structure of complement receptor 2 in complex with its C3d ligand.
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| Szakonyi G, Guthridge JM, Li D, Young K, Holers VM, Chen XS.
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| Science. 292(5522):1725-8. 2001
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14 | CR2
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| CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21.
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| Aubry JP, Pochon S, Gauchat JF, Nueda-Marin A, Holers VM, Graber P, Siegfried C, Bonnefoy JY.
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| J Immunol. 152(12):5806-13. 1994
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15 | CR2
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| Interaction of iC3b with recombinant isotypic and chimeric forms of CR2.
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| Kalli KR, Ahearn JM, Fearon DT.
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| J Immunol. 147(2):590-4. 1991
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16 | CR2
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| Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.
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| Matsumoto AK, Kopicky-Burd J, Carter RH, Tuveson DA, Tedder TF, Fearon DT.
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| J Exp Med. 173(1):55-64. 1991
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17 | CR2
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| Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.
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| Tuveson DA, Ahearn JM, Matsumoto AK, Fearon DT.
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| J Exp Med. 173(5):1083-9. 1991
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18 | CR2
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| Epstein Barr virus/complement C3d receptor is an interferon alpha receptor.
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| Delcayre AX, Salas F, Mathur S, Kovats K, Lotz M, Lernhardt W.
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| EMBO J. 10(4):919-26. 1991
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19 | CR2
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| Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes.
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| Moore MD, Cooper NR, Tack BF, Nemerow GR.
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| Proc Natl Acad Sci U S A 84 : 9194-9198. 1987
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20 | RCA@, CR2
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| Quantitative variations of the C3b/C4b receptor (CRI) in human erythrocytes are controlled by genes within the regulator of complement activation (RCA) gene cluster.
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| Rodriguez de Cordoba S, et al.
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| J Exp Med 164 : 1274-1283. 1986
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