| 1 | ASIP, CDK4, CDKN2A, CMM1, CMM2, CMM20, CMM3, CMM4, MC1R, TYR, TYRP1
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| Genetic risk factors for melanoma.
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| Meyle KD, Guldberg P.
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| Hum Genet 126(4):499-510. Epub 2009 Jul 8. Review.
2009
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| 2 | CMM2, CDKN2A, DEL9P
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| Multiple primary tumors associated with chromosome 9p deletion.
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| Lindor NM, Jalal SM, Kumar S, Lteif AN.
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| Am J Med Genet A 143(1):95-7. No abstract available. 2007
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| 3 | CDKN2A ,CMM2
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| Features associated with germline CDKN2A mutations: a GenoMEL study of melanoma-prone families from three continents.
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| Goldstein AM, Chan M, Harland M, Hayward NK, Demenais F, Timothy Bishop D, Azizi E, Bergman W, Bianchi-Scarra G, Bruno W, Calista D, Cannon Albright LA, Chaudru V, Chompret A, Cuellar F, Elder DE, Ghiorzo P, Gillanders EM, Gruis NA, Hansson J, Hogg D, Holland EA, Kanetsky PA, Kefford RF, Teresa Landi M, Lang J, Leachman SA, Mackie RM, Magnusson V, Mann GJ, Newton Bishop J, Palmer JM, Puig S, Puig-Butille JA, Stark M, Tsao H, Tucker MA, Whitaker L, Yakobson E.
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| J Med Genet 44(2):99-106. Epub 2006 Aug 11. 2007
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| 4 | CMM2
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| Impact of E27X, a novel CDKN2A germ line mutation, on p16 and p14ARF expression in Italian melanoma families displaying pancreatic cancer and neuroblastoma.
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| Ghiorzo P, Gargiulo S, Pastorino L, Nasti S, Cusano R, Bruno W, Gliori S, Sertoli MR, Burroni A, Savarino V, Gensini F, Sestini R, Queirolo P, Goldstein AM, Scarra GB.
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| Hum Mol Genet 15(18):2682-9. Epub 2006 Aug 7. 2006
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| 5 | CMM2
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| Mutation screening of the CDKN2A promoter in melanoma families.
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| Harland M, Holland EA, Ghiorzo P, Mantelli M, Bianchi-Scarra G, Goldstein AM, Tucker MA, Ponder BA, Mann GJ, Bishop DT, Newton Bishop J.
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| Genes Chromosomes Cancer 28(1):45-57. 2000
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| 6 | CDKN2A, CMM2
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| Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma.
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| Liu L, Dilworth D, Gao L, Monzon J, Summers A, Lassam N, Hogg D.
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| Nat Genet 21 : 128-132. 1999
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| 7 | CDKN2A, CMM2
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| CDKN2A mutations in multiple primary melanomas.
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| Monzon J, et al.
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| N Engl J Med 338 : 879-887. 1998
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| 8 | CDKN2A, CDKN2B, CMM2, TSG9A
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| Mutations of p16 and p15 tumor suppressor genes and replication errors contribute independently to the pathogenesis of sporadic malignant melanoma.
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| Matsumura Y, et al.
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| Arch Dermatol Res 290 : 175-180. 1998
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| 9 | CDKN2B, CMM2
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| Homozygous deletions at chromosome 9p21 involving p16 and p15 are associated with histologic progression in follicle center lymphoma.
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| Elenitoba-Johnson KS, et al.
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| Blood 91 : 4677-4685. 1998
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| 10 | CDKN2A, CDKN2B, CMM2
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| Affected members of melanoma-prone families with linkage to 9p21 but lacking mutations in CDKN2A do not harbor mutations in the coding regions of either CDKN2B or p19ARF.
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| Liu L, et al.
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| Genes Chromosomes Cancer 19 : 52-54. 1997
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| 11 | CDKN2A, CMM2, TSG9A
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| Loss of expression of the p16INK4/CDKN2 gene in cutaneous malignant melanoma correlates with tumor cell proliferation and invasive stage.
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| Talve L, Sauroja I, Collan Y, Punnonen K, Ekfors T.
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| Int J Cancer 74(3):255-9. 1997
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| 12 | CMM1, CMM2
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| Two-locus linkage analysis of cutaneous malignant melanoma/dysplastic nevi.
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| Goldstein AM, et al.
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| Am J Hum Genet 58 : 1050-1056. 1996
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| 13 | CDK4, CDKN2A, CMM2, TSG9A
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| Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma : analysis of a clinic-based population.
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| Fitzgerald MG, et al.
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| Proc Natl Acad Sci U S A 93 : 8541-8545. 1996
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| 14 | CDKN2A, CDKN2B, CMM2, TSG9A
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| Chromosome 9 related aberrations and deletions of the CDKN2 and MTS2 putative tumor suppressor genes in human chondrosarcomas.
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| Jagasia AA, et al.
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| Cancer Lett 105 : 91-103. 1996
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| 15 | CDKN2A, CMM2, TSG9A
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| Infrequent mutation of p16INK4 in sporadic melanoma.
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| Healy E, et al.
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| J Invest Dermatol 107 : 318-321. 1996
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| 16 | TSG9A, CDKN2A, CMM2
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| Frequency of homozygous deletion at p16/CDKN2 in primary human tumours.
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| Cairns P, Polascik TJ, Eby Y, Tokino K, Califano J, Merlo A, Mao L, Herath J, Jenkins R, Westra W, et al.
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| Nat Genet 11 : 210-212. 1995
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| 17 | CDKN2A, CMM2, TSG9A
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| Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations.
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| Goldstein AM, Fraser MC, Struewing JP, Hussussian CJ, Ranade K, Zametkin DP, Fontaine LS, Organic SM, Dracopoli NC, Clark WH Jr, et al.
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| N Engl J Med 333 : 970-974. 1995
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| 18 | CDKN2A, CMM2, TSG9A
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| A familial syndrome of pancreatic cancer and melanoma with a mutation inthe CDKN2 tumor-suppressor gene.
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| Whelan AJ, Bartsch D, Goodfellow PJ.
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| N Engl J Med 333 : 975-977. 1995
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| 19 | CMM2, CDKN2A
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| Mutations associated with familial melanoma impair p16ink4 function.
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| Ranade K, et al.
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| Nat Genet 10 : 114-116. 1995
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| 20 | CDKN2A, CMM2
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| Germline p16INK4A mutation and protein dysfunction in a family with inherited melanoma.
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| Liu L, et al.
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| Oncogene 11 : 405-412. 1995
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| 21 | CDKN2A, TSG9A, CMM2
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| Chromosome 9p deletions in cutaneous malignant melanoma tumors : The minimal deleted region involves markers outside the p16 (CDKN2) gene.
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| Puig S, et al.
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| Am J Hum Genet 57 : 395-402. 1995
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| 22 | CMM2, CDKN2A
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| Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds.
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| Gruis NA, et al.
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| Nat Genet 10 : 351-353. 1995
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| 23 | CMM2, CDKN2A
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| Mutation frequency of the p16/CDKN2 gene in primary cancers in the upper digestive tract.
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| Igaki H, et al.
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| Cancer Res 55 : 3421-3423. 1995
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| 24 | TSG9A, CMM2
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| Refined localization of the melanoma (MLM) gene on chromosome 9p by analysis of allelic deletions.
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| Walker GJ, et al.
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| Oncogene 9 : 819-824. 1994
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| 25 | CMM2
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| Linkage of cutaneous malignant melanoma/dysplastic nevi to chromosome 9p, and evidence for genetic heterogeneity.
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| Goldstein AM, et al.
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| Am J Hum Genet 54 : 489-496. 1994
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| 26 | CMM2, TSG9A
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| Loss of heterozygosity and homozygous deletions on 9p21-22 in melanoma.
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| Holland EA, et al.
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| Oncogene 9 : 1361-1365. 1994
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| 27 | CDKN2A, CMM2
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| Germline p16 mutations in familial melanoma.
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| Hussussian CJ, et al.
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| Nat Genet 8 : 15-21. 1994
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| 28 | CMM2
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| Genetic heterogeneity in familial malignant melanoma.
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| MacGeoch C, et al.
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| Hum Mol Genet 3 : 2195-2200. 1994
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| 29 | CMM2
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| Incidence of familial melanoma and MLM2 gene.
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| Battistutta D, et al.
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| Lancet 344 : 1607-1608. 1994
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| 30 | CDKN2A, CMM2
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| Penetrance and expressivity of the chromosome 9p melanoma susceptibility locus (MLM).
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| Cannon-Albright LA, et al.
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| Cancer Res 54 : 6041-6044. 1994
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| 31 | CDKN2A, TSG9A, CMM2
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| P16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma.
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| Cheng JQ, et al.
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| Cancer Res 54 : 5547-5551. 1994
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| 32 | CMM2, CDKN2A
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| Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus.
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| Kamb A, et al.
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| Nat Genet 8 : 22-26. 1994
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| 33 | TSG9A, CMM2
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| Localization of the 9p melanoma susceptibility locus (MLM) to a 2-cM region between D9S736 and D9S171.
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| Cannon-Albright LA, et al.
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| Genomics 23 : 265-268. 1994
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| 34 | CMM2, TSG9A
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| Molecular definition of a chromosome 9p21 germ-line deletion in a woman with multiple melanomas and a plexiform neurofibroma : implications for 9p tumor-suppressor gene(s).
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| Petty EM, et al.
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| Am J Hum Genet 53 : 96-104. 1993
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| 35 | CMM2
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| Cutaneous malignant melanoma and atypical moles associated with a constitutional rearrangement of chromosomes 5 and 9.
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| Petty EM, et al.
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| Am J Med Genet 45 : 77-80. 1993
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| 36 | CMM2
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| Confirmation of chromosome 9p linkage in familial melanoma.
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| Nancarrow DJ, et al.
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| Am J Hum Genet 53 : 936-942. 1993
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| 37 | CMM2
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| Assignment of a locus for familial melanoma MLM, to chromosome 9p13-p22.
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| Cannon-Albright LA, et al.
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| Science 258 : 1148-1151. 1992
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| 38 | CMM2, TSG9A
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| Homozygous deletions within human chromosome band 9p21 in melanoma.
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| Fountain JW, et al.
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| Proc Natl Acad Sci U S A 89 : 10557-10561. 1992
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| 39 | CMM2
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| Linkage mapping of melanoma (MLM) using 172 microsatellite markers.
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| Nancarrow DJ, et al.
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| Genomics 14 : 939-947. 1992
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