| 1 | C8A, C8B, C8G
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| Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
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| Lovelace LL, Cooper CL, Sodetz JM, Lebioda L.
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| J Biol Chem 286(20):17585-92. Epub 2011 Mar 25.
2011
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| 2 | C8A, C8B, C8G
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| Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
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| Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM.
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| J Mol Biol 379(2):331-42. Epub 2008 Apr 3.
2008
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| 3 | C8A
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| Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense.
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| Hadders MA, Beringer DX, Gros P.
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| Science 317(5844):1552-4. 2007
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| 4 | C8A, C8B, C8G, C9
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| Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.
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| Slade DJ, Chiswell B, Sodetz JM.
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| Biochemistry 45(16):5290-6. 2006
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| 5 | C8A, C8B, C8G
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| Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential.
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| Parker CL, Sodetz JM.
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| Mol Immunol 39(7-8):453-8. 2002
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| 6 | C8A, C8B, C8G
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| Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.
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| Musingarimi P, Plumb ME, Sodetz JM.
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| Biochemistry 41(37):11255-60. 2002
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| 7 | C8A, C9
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| Binding of human complement C8 to C9: role of the N-terminal modules in the C8 alpha subunit.
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| Scibek JJ, Plumb ME, Sodetz JM.
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| Biochemistry 41(49):14546-51. 2002
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| 8 | C8A, C8B, C8G
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| An indel within the C8 alpha subunit of human complement C8 mediates intracellular binding of C8 gamma and formation of C8 alpha-gamma.
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| Plumb ME, Sodetz JM.
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| Biochemistry 39(42):13078-83. 2000
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| 9 | C8A
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| Genetic basis of human complement C8 alpha-gamma deficiency.
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| Kojima T, et al.
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| J Immunol 161 : 3762-3766. 1998
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| 10 | C8A, C8B
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| Physical linkage and orientation of the human complement C8alpha and C8beta genes on chromosome 1p32.
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| Platteborze PL, et al.
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| Hum Genet 98 : 443-446. 1996
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| 11 | C8A, C8B
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| Genomic organization of human complement protein C8alpha and further examination of its linkage to C8beta.
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| Michelotti GA, et al.
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| Hum Genet 95 : 513-518. 1995
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| 12 | C8A
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| The eighth component of human complement : molecular basis of C8A (C81) polymorphism.
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| Zhang L, et al.
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| Hum Genet 96 : 281-284. 1995
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| 13 | C8A
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| Human complement C81 (C8 A) polymorphism : detection and segregation of new variants.
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| Rittner C, et al.
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| Hum Genet 92 : 413-416. 1993
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| 14 | C8A, C8B
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| Regional chromosomal assignment of genes encoding the alpha and beta subunits of human complement protein C8 to 1p32.
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| Theriault A, et al.
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| Hum Genet 88 : 703-704. 1992
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| 15 | C8A, C8B
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| Linkage and association studies with C8A and C8B RFLPs on chromosome 1.
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| Rogde S, et al.
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| Ann Hum Genet 56 : 233-242. 1992
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| 16 | C8A
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| A BamHI RFLP of the C8A gene.
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| Rogde S, et al.
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| Nucleic Acids Res 19 : 3762. 1991
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| 17 | D1S2, C8A, PGM1
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| D1S2 is close to C8A and distal to PGM1 in Norwegian families.
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| Hyheim B, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 1855. 1991
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| 18 | C8A, C8B
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| Evidence of close physical linkage between loci encoding human complement proteins C8-alpha and C8-beta.
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| Snider JV, et al.
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| FASEB J 3 : A802. 1989
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| 19 | C8A, C8B, C8G
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| Chromosomal assignment of genes encoding the alpha, beta, and gamma subunits of human complement protein C8 : identification of a close physical linkage between the alpha and the beta loci.
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| Kaufman KM, et al.
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| Genomics 5 : 475-480. 1989
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| 20 | C8A, C8B, C8G
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| The eighth component of human complement (C8): Evidence that it is an oligomeric serum protein assembled from products of three different genes.
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| Ng SC, Rao AG, Howard OM, Sodetz JM.
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| Biochemistry 26 : 5229-5233. 1987
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| 21 | C8A, C8B
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| The C8A and C8B loci are closely linked on chromosome 1.
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| Rogde S, et al.
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| Ann Hum Genet 50 : 139-144. 1986
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| 22 | C8A
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| Human C81 (alpha-gamma) polymorphism : Detection in the alpha-gamma subunit on SDS-PAGE, formal genetics and linkage relationship.
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| Rittner C, et al.
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| Am J Hum Genet 38 : 482-491. 1986
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| 23 | C8A
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| Structural gene(s) for complement factor C8 (C8) on chromosome 1.
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| Rogde S, et al.
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| (HGM7) Cytogenet Cell Genet 37 : 571. 1984
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| 24 | C8A
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| Genetic polymorphism of complement component C8.
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| Mevag B, et al.
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| Proc 10th Congr Haematogenet Munchen 1983
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| 25 | C8A
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| Genetic polymorphism in C8 beta-chains : Evidence for two unlinkedgenetic loci for the eighth component of human complement (C8).
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| Alper CA, et al.
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| J Clin Invest 72 : 1526-1531. 1983
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