Home Page
References OMIM Gene GeneReviews HGMD HGNC
last update : 02-12-2013
Symbol XPDS
Location Xp11.4
Name Parkinsonism with spasticity, X-linked
Corresponding gene ATP6AP2
Main clinical features
  • parkinsonian features and variably penetrant spasticity with age at symptom onset ranged from 14 to 50 years
  • classic features of cogwheel rigidity, resting tremor, and bradykinesia, or spasticity with hyperreflexia and extensor plantar responses
  • Genetic determination sex linked
    Function/system disorder neurology
    Type disease