Home Page |
Orphanet | References | OMIM | Gene | GeneReviews | HGMD | HGNC |
GENATLAS PHENOTYPE |
last update : 17-01-2009 |
Symbol | XPC | |||
Location | 3p25.1 | |||
Name | xeroderma pigmentosum, complementation group C | |||
Corresponding gene | XPC | |||
Other symbol(s) | XPCC | |||
Main clinical features | hypersensitivity to ultraviolet light.; the cells of xeroderma pigmentosum patients are defective in nucleotide excision repair, limiting their capacity to eliminate ultraviolet-induced DNA damage, and resulting in a strong predisposition to develop skin cancers | |||
Genetic determination
Function/system disorder
| dermatology | Type
| disease
| |
Remark(s) |
|