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GENATLAS PHENOTYPE
last update : 13/10/2007
Symbol TRDF
Location 4q32.1
Name thrombosis, recurrent, dysfibrinogenemic type (fibrinogen A, B or G defect)
Corresponding gene FGA , FGB , FGG
Main clinical features
  • clot formation was diminished, but unexpectedly, fibrinolysis was also delayed ; when clot lysis was assayed with trypsin substituted for plasminogen, a significant delay was also observed
  • Genetic determination
    Function/system disorder hematology
    Type disease
    Gene product
    Name fibrinogen, alpha, beta or gamma polypeptide (FGA, FGB, FGG)
    Remark(s)