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GENATLAS PHENOTYPE

last update : 24-01-2022

Symbol	TCF3
Location	19p13.3, 1q23
Name	pre-B cell acute lymphoblastic leukemia, LAL1, LAL pre B
Corresponding gene	TCF3 , PBX1
Main clinical features	with translocation t(1;19)(q23;p13)
Genetic determination	other
Function/system disorder	hematology
Type	malignancy

Gene product

Name	chimeric fusion protein 5'-TCF3-PBX1-3'

Mechanism(s)

Gene mutation	Chromosome rearrangement	Effect	Comments
	translocation		with somatic, tumoral translocation t(1;19)(q23;p13)

Remark(s)