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References OMIM Gene GeneReviews HGMD HGNC
last update : 24-01-2009
Symbol SSCA
Location 18q12.1
Name amyloidosis, senile, systemic/cardiac (TTR deposit)
Corresponding gene TTR
Main clinical features
  • senile systemic amyloidosis, also referred to as senile cardiac amyloidosis, involves the lungs, liver, and kidneys as well as the heart
  • primary structure of the amyloid protein in this disorder is similar to that of human prealbumin
  • Genetic determination multigenic
    Function/system disorder connective tissue
    Type susceptibility factor
    Gene product
    Name transthyretin (prealbumin)