Home Page
References OMIM Gene GeneReviews HGMD HGNC
last update : 04/11/06
Symbol SMAPA
Location 20q13.32
Name spinal muscular atrophy proximal, adult type
Other name(s) Finkel type of late-onset autosomal dominant spinal muscular atrophy
Corresponding gene VAPB
Main clinical features
  • degeneration of the anterior horn cells in the spinal cord, leading to symmetric muscle weakness and wasting, age at disease onset >30 years, slowly progressive spinal muscular atrophy
  • Genetic determination autosomal dominant
    Function/system disorder neuromuscular
    Type disease