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References OMIM Gene GeneReviews HGMD HGNC
last update : 03-07-2009
Symbol SIADH
Location Xq28
Name inappropriate secretion of antidiuretic hormone
Corresponding gene AVPR2
Main clinical features
  • symptomatic hyponatraemia, intermittent or water load induced-hyponatraemia with unmeasurable circulating AVP concentrations
  • Genetic determination autosomal dominant
    Function/system disorder kidney and urinary tract
    Type disease
    Remark(s) activating mutation in the AVPR2 with resultant nephrogenic syndrome of inappropriate antidiuresis (Soule 2008)