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References OMIM Gene GeneReviews HGMD HGNC
last update : 12-05-2014
Symbol PUPSO
Location 2q36.1
Name Pustular Psoriasis
Other name(s) generalized pustular psoriasis
Corresponding gene AP1S3
Other symbol(s) GPP
Main clinical features
  • severe autoinflammatory skin disorder
  • often manifest with concomitant plaque psoriasis; generalized pustular psoriasis is the most severe form of the disease and is characterized by acute, potentially life-threatening episodes of skin pustulation and systemic inflammation
  • Genetic determination not applicable
    Function/system disorder defense and immunity
    Type disease