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GENATLAS PHENOTYPE

last update : 5/09/2006

Symbol	PTNS
Location	11p15.5
Name	personality trait of novelty seeking
Corresponding gene	DRD4
Main clinical features	characterized as impulsive, exploratory, fickle, excitable, quick-tempered, and extravagant, whereas those who score lower than average tend to be reflective, rigid, loyal, stoic, slow-tempered, and frugal
Genetic determination	multigenic
Function/system disorder	psychiatric disorder
Type	susceptibility factor

Remark(s)

associated with a polymorphism in exon 3 of DRD4, accounting for about 10% of the genetic variation of the trait, in some series but inconsistent results in others