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| GENATLAS PHENOTYPE |
| last update : 29-01-2009 |
| Symbol | PTC1 |
| Location | 10q21.2 and 10q11.2 |
| Name | PTC1 chimeric oncogene |
| Other name(s) | H4/RET oncogene |
| Corresponding gene | CCDC6 , RET |
| Main clinical features | somatic fusion gene, in papillary thyroid carcinoma |
| Genetic determination | somatic |
| Function/system disorder | endocrinology |
| Type | malignancy |
| Mechanism(s) |
| Gene mutation | Chromosome rearrangement | Effect | Comments |
| other
| inversion
|
| somatic paracentric inv(10)(q11.2q21)
| |
| Remark(s) | PTC1 oncogene occurs in as many as 30% of papillary thyroid carcinomas |