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References OMIM Gene GeneReviews HGMD HGNC
last update : 27-12-2017
Location 10q23.31
Name Proteus-like syndrome
Other name(s)
  • SOLAMEN syndrome (Segmental overgrowth, Lipomatosis, Arteriovenous Malformation and Epidermal Nevus)
  • Corresponding gene PTEN
    Other symbol(s) PROTS, SOLAMEN
    Main clinical features
  • gigantism, partial, of hands and feet, nevi, hemihypertrophy, and macrocephaly
  • Genetic determination autosomal dominant
    Function/system disorder osteo-articular
    connective tissue
    Type disease
    Gene product
    Name phosphatase and tensin homolog
    Remark(s) grouped with its allelic disorders Bannayan-Zonana syndrome (BZS) and Cowden syndrome and classified as the PTEN hamartomas syndrome (PHTS)