Home Page
References OMIM Gene GeneReviews HGMD HGNC
last update : 05-12-2008
Symbol PPNAD2
Location 2q31.2
Name primary pigmented nodular adrenocortical disease-2
Corresponding gene PDE11A
Main clinical features
  • Cushing syndrome and adrenocortical hyperplasia
  • at histology of adrenal gland, diffuse cortical hyperplasia with mostly nonpigmented nodules, multiple capsular deficits, and massive circumscribed and infiltrating extraadrenal cortical excrescences with micronodules
  • Genetic determination autosomal dominant
    Function/system disorder endocrinology
    Type disease